Clinical trials: PrEP Uptake
PrEP Uptake Experiences, PrEP Adherence Experiences
Trans STAIR: Implementing an Evidence Based Trauma Treatment With Community Led PrEP Navigation
This pilot trial will leverage "PrEP Well," an ongoing multi-level implementation strategy for providing PrEP in transgender/gender diverse (TGD)-serving contexts by integrating peer-led PrEP navigation with programming that…
- Conditions
- PrEP Uptake Experiences, PrEP Adherence Experiences, Mental Health Symptoms
- Trial name
- NCT06724965
- Testing
- Trans STAIR, PrEP Well
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- San Diego State University
Drug Use Disorders, PrEP Uptake
Reducing Co-occurring Substance Use and HIV Risk Among Stimulant-using Men at High Risk for HIV in the United States of America.
This intervention will focus on stimulant-using men at high risk for HIV who are in need of tailored behavioral interventions to mitigate co-occurring stimulant use and HIV risk in the era of pre-exposure prophylaxis (PrEP).
- Conditions
- Drug Use Disorders, PrEP Uptake, PrEP Adherence, HIV Risk Behavior
- Trial name
- NCT07281378
- Testing
- Tailored Positive Affect Intervention, Contingency Management
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Florida
PrEP Uptake
Mixed-methods Protocol for the WiSSPr Study
WiSSPr is a prospective observational cohort study grounded in community-based participatory research principles with a community advisory board (CAB) of key population (KP) civil society organi sations (KP-CSOs) and the Ministry…
- Trial name
- WiSSPr (NCT06898112)
- Testing
- PrEP
- Where
- Zambia
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
HIV Prevention, PrEP Awareness
Leveraging Chatbot to Improve PrEP in the Southern United States
The purpose of this study is to develop a chatbot intervention to promote PrEP awareness and uptake among Black men who have sex with men (MSM) in the Southern United States.
- Conditions
- HIV Prevention, PrEP Awareness, PrEP Uptake
- Trial name
- NCT05968755
- Testing
- A chatbot designed to promote PrEP awareness and uptake for Black MSM, General educational messages
- Where
- 4 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Yale University
Gonorrhea Female, Chlamydia Females
The Integrated Female Sexually Transmitted Infection Testing for HIV Epidemic Control Through PrEP (IN-STEP) Study
Globally, new HIV infections are concentrated in eastern and southern Africa where the infections are largely acquired by women outside of known key populations.
- Conditions
- Gonorrhea Female, Chlamydia Females, Syphilis Female, Trichomonas Vaginalis
- Trial name
- IN-STEP (NCT06743204)
- Testing
- Self-Reported Risk Screening for PrEP and Diagnostic STI testing, Self-reported risk screening for PrEP and syndromic management for STIs
- Where
- Uganda
- Volunteers
- 5,560 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV Testing, PrEP Uptake
P3 Trial: Estimating the Impact of a Multilevel, Multicomponent Intervention to Increase Uptake of HIV Testing and Biomedical HIV Prevention
The major goal of this study is to evaluate a multi-component, multilevel HIV prevention intervention that targets theoretically-informed and empirically-identified barriers to and facilitators of both HIV testing and PEP/PrEP…
- Trial name
- P3 (NCT06785376)
- Testing
- DIY (Do It Yourself), TRUST, SOC
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Columbia University
Alcohol Consumption, PrEP Uptake
Enhancing HIV Prevention and Reducing Alcohol Use Among People Receiving STI Care in Lilongwe, Malawi
Purpose: To evaluate short-term efficacy and implementation of Treat4All, an alcohol reduction evidence-based intervention, for decreasing heavy drinking and optimizing HIV outcomes (viral suppression among People with HIV (PWH)…
- Conditions
- Alcohol Consumption, PrEP Uptake, Recent Heavy Drinking, HIV Prevention
- Trial name
- Treat4All (NCT06668363)
- Testing
- Treat4All, Standard of care (control arm)
- Where
- Malawi
- Volunteers
- 130 people
- Sponsor
- University of North Carolina, Chapel Hill
PrEP, PrEP Adherence Experiences
PrEP-LANA (Pre-exposure Prophylaxis- Long-acting Novel Antiviral Agent)
The goal of this 12-month implementation science study is to generate the evidence required to ensure long-acting cabotegravir (LA CAB) as pre-exposure prophylaxis (PrEP) can be delivered in an equitable manner within the NHS.
- Conditions
- PrEP, PrEP Adherence Experiences, PrEP Adherence Perspectives, PrEP Uptake
- Trial name
- PrEP-LANA (NCT07620730)
- Volunteers
- 220 people
- Sponsor
- Queen Mary University of London
PrEP Uptake
PrEP Optimization Among Women to Enhance Retention and Uptake
Black women experience one of the highest incidences of HIV among all subpopulations in the United States, but pre-exposure prophylaxis (PrEP) use among Black cisgender women is very limited.
- Trial name
- POWER Up (NCT05626452)
- Testing
- PrEP Education, Provider training, EMR Optimization
- Where
- United States
- Volunteers
- 724 people, healthy volunteers welcome
- Sponsor
- University of Chicago
HIV Self-testing, Male Partners of HIV-negative Postpartum Women
HIV Self-testing for Partners of HIV-uninfected Postpartum Women
The purpose of this study is to test the feasibility and acceptability of a combination intervention to promote HIV self-testing (HIVST) for Partners and PrEP uptake for HIV-uninfected Postpartum Women ("H4P").
- Conditions
- HIV Self-testing, Male Partners of HIV-negative Postpartum Women, PrEP Uptake, Feasibility
- Trial name
- NCT07194902
- Testing
- HIVST for Partners and PrEP uptake for HIV-uninfected Postpartum Women ("H4P").
- Where
- South Africa
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
HIV, PrEP
PrOTECT AL: PrEP Optimization Through Enhanced Continuum Tracking
The purpose of this study is to enhance and evaluate the implementation of a PrEP Care Continuum data dashboard across seven distinct clinical sites in Alabama.
- Conditions
- HIV, PrEP, PrEP Uptake, HIV Prevention
- Trial name
- PrOTECT AL (NCT07231640)
- Testing
- PrOTECT AL Implementation Strategy
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Alabama at Birmingham
PrEP Uptake
PrEP US NoW: PrEP Utilization Through Increasing Social Capital Among YBMSM Networks With Women
This project is a randomized intervention looking at PrEP uptake among young, black men who identify as gay, bisexual, or same gender loving, utilizing black females within the community to help deliver study related topics.
- Trial name
- NCT07024745
- Testing
- Intervention Group, Control (Standard treatment)
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
PrEP Uptake, HIV
Implementation of PrEP Care Among Women in Family Planning Clinics
This study will evaluate implementation strategies to address barriers and increase uptake of PrEP among Black cisgender women in Planned Parenthood of Illinois (PPIL) health centers.
- Conditions
- PrEP Uptake, HIV, Prevention
- Trial name
- NCT06335121
- Testing
- POWER Up strategies -
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
HIV Antibody Positivity, PrEP Uptake
PrEP for Prevention of HIV Transmission Among People Who Inject Drugs in Nairobi, Kenya
The investigators broadly aim at determining barriers and facilitators to PrEP uptake and adherence and retention among the study participants.
- Trial name
- NCT05465265
- Testing
- Navigation into prEP by use of PrEP-UP intervention (provision of PrEP information through 5 counselling sessions, peer support, booking of appointments for PWIDs)
- Where
- Kenya
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Washington
PrEP Uptake Perspectives, PrEP Uptake Experiences
Exploring the Perspectives and Experiences of PrEP-eligible Black Women in Texas in Relation to Readiness for PrEP Uptake and Adherence
The aim is to conduct two virtual focus groups (10 participants in each group) with 20 pre-exposure prophylaxis (PrEP)-eligible Black women in Houston and Austin, TX.
- Conditions
- PrEP Uptake Perspectives, PrEP Uptake Experiences, PrEP Adherence Perspectives, PrEP Adherence Experiences
- Trial name
- NCT05530993
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
PrEP Uptake
MI-based PrEP Intervention
Gay, bisexual and other men who have sex with men (MSM) are the group at highest risk of HIV infection in the United States. Pre-exposure prophylaxis (PrEP) has demonstrated high efficacy in preventing HIV infection among MSM.
- Trial name
- NCT03313765
- Testing
- Motivational interviewing (MI), Standard-of-care
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
PrEP Uptake, HIV Seronegativity
Pre-exposure Prophylaxis Accessibility Research and Evaluation 2
This study is a controlled, un-blinded, two-arm, randomized (1:1) clinical trial to determine if providing high-risk subjects with a calculated risk score changes the likelihood of pre-exposure prophylaxis (PrEP) uptake.
- Trial name
- PrEPARE2 (NCT02125773)
- Testing
- Informed Risk Score
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
HIV Prevention, PrEP Uptake
Social Media Based Peer-Led Intervention for HIV Prevention
The purpose of this study is to test the feasibility, acceptability, and preliminary efficacy of E-PrEP on reaching young men of color who have sex with men (YMCSM) at high-risk of HIV infection to reduce HIV acquisition.
- Trial name
- NCT03213366
- Testing
- E-PrEP- Peer-Led Intervention about PrEP, BxNow - General Health Campaign
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
PrEP Uptake, Stimulant Abuse
Pepped on Pre-exposure Prophylaxis (PrEP): A Counseling and Problem-Solving PrEP Adherence Intervention for Stimulant Using Men Who Have Sex With Men (MSM).
Pepped on PrEP is an innovative pilot RCT designed by an interdisciplinary team to develop a counseling and problem-solving PrEP adherence intervention with a Behavioral Activation (BA) approach that aims to re-engage…
- Conditions
- PrEP Uptake, Stimulant Abuse, Adherence, Medication
- Trial name
- NCT03137342
- Testing
- Pepped on PrEP Package
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Brown University