Clinical trials: Practice-based Evidence
CONTINUING MEDICAL EDUCATION
Development and Evaluation of Hygie, a New Serious Game for Continuing Medical Education of General Practitioners
We produced a prototype video game called Hygie on the 5 most common reasons of consultation in general practice using 9 articles from independent journals based on evidence (reviews by Prescrire and Minerva).
- Trial name
- NCT03486275
- Testing
- Hygie, Source articles
- Where
- France
- Volunteers
- 3,398 people, healthy volunteers welcome
- Sponsor
- Hygie
Autism
Autism Intervention Research Network for Behavioral Health (AIR-B II): Deployment Into Elementary Schools
The primary goal of this study is to identify efficacious and cost effective intervention strategies that can improve academic and psychological outcomes for children with ASD, and can be feasibly be implemented at fidelity by…
- Trial name
- AIR-B II (NCT01724047)
- Testing
- Playground Intervention, STAT Intervention
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Health Resources and Services Administration (HRSA)
Prescribing
Testing CDS in OSCAR EMR Using STOPP Criteria
This mixed methods study seeks to assess and understand the impact of using an advanced CDS tool to present the STOPP criteria to support prescribers at the point of decision-making.
- Trial name
- STOPP-RCT (NCT02130895)
- Testing
- STOPP Criteria Decision Support Content
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Delivery;Breech;Stillbirth
Investigation of the Effect of Supporting Nursing Care Provided in Line With During Intrapartum Period
Aim: The aim of the research was to examine the effect of supportive nursing care provided in line with evidence-based practices during the intrapartum period.
- Trial name
- Support (NCT06024811)
- Testing
- supporting nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Long-Term Care, Accidental Falls
Pragmatic Trial to Increase Quality of Care in State Veterans Homes
Background: State Veterans Home nursing homes (SVHs) care for 51% of all Veterans receiving VA-funded nursing home care. SVHs cost VA $1.2 billion yearly in per diem payments.
- Trial name
- TEAM EFFORT (NCT05906095)
- Testing
- LOCK Falls Program
- Where
- United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Human Papillomavirus Vaccines, Adolescent Health Services
HPV Vaccine Communication ECHO for Primary Care Clinics
The safe, highly-effective human papillomavirus (HPV) vaccine remains underused in the US; only 51% of 13- to 17-year-old girls and boys were up-to-date by 2018.
- Trial name
- NCT04587167
- Testing
- Project ECHO, Announcement Approach Training, Recall notices
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Opioid-use Disorder
Intervention to Expand Opioid Use Disorder Treatment Pharmacotherapy Prescribers
This is a cluster-randomized controlled trial designed to increase the availability of buprenorphine and extended-release naltrexone treatment capacity for opioid use disorder (OUD).
- Trial name
- NCT02926482
- Testing
- Prescriber Recruitment Bundle (PRB)
- Where
- 3 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Implementation Science
An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety Around Suicide Prevention
Study objectives are to design and pilot test a novel, exposure-based implementation strategy (EBIS) directly targeting clinician anxiety and low self-efficacy for use of evidence-based suicide screening, assessment, and…
- Trial name
- NCT05172609
- Testing
- Exposure Based Implementation Strategy (EBIS), Implementation as Usual (IAU)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dyslipidemia, Diabetes
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Fructose-containing sugars have been implicated in the epidemics of obesity, diabetes and related cardiometabolic disorders. This view is supported by lower quality evidence from ecological observations, animal models, and select…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT02716870
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Early Childhood Caries, Oral Hygiene
Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries
Few educational oral health applications, directed to the preschool children under the age of six years are available world-wide.
- Conditions
- Early Childhood Caries, Oral Hygiene, Oral Health
- Trial name
- FU-APP (NCT05515510)
- Testing
- FU-APP, Oral health recommendations
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Hypertension
VISN Collaborative for Improving Hypertension Management With ATHENA-HTN
This project is a VA HSR\&D-funded Quality Enhancement Research Initiative (QUERI) project to translate into practice evidence about clinical management of primary hypertension.
- Trial name
- HTN (NCT00374452)
- Testing
- ATHENA-CDS-HTN plus Guideline Link, Guideline Link Only
- Where
- 7 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Disease, Cancer
Evaluation of the Effectiveness and Implementation of the BETTER Women Peer Health Coaching Program
The Building on Existing Tools To improvE cancer and chronic disease pRevention and screening in primary care (BETTER) Program allows patients in primary care to have a dedicated visit with a prevention practitioner to discuss…
- Trial name
- NCT04746859
- Testing
- Prevention Visit, Peer health coaching
- Where
- 3 sites in Canada
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Health Knowledge, Attitudes, Practice
Randomised Trial of Two Educational Intervention for Improving Evidence-based Practice Knowledge, Atttitudes and Practice
This pragmatic randomised controlled trial (RCT) used a two-group parallel design with matched-pair stratification by type (clinician/manager) and knowledge score.
- Trial name
- OTEBP (NCT01512823)
- Testing
- Education
- Where
- South Africa
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Upper Respiratory Tract Infection, URTI
Translating Clinicians' Beliefs Into Implementation Interventions (TRACII)
Using a theory-based approach, the purpose of this study is to identify modifiable factors underlying professional behaviour in order to identify those processes to target with an implementation intervention and to gain an…
- Trial name
- NCT00376142
- Testing
- Psychological theory-based behaviour change interventions
- Where
- United Kingdom
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Depression
Remote Training in Evidence-based Practices for Clinicians Who Work With Migrant Workers
This study will compare training as usual to automated training using an intelligent tutoring system in training bachelors (BA) level social workers in cognitive behavioral therapy (CBT).
- Trial name
- NCT03515226
- Testing
- ITS based training, Traditional Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Washington
Clinical Decision-Making, Decision Making, Computer-assisted
A Study to the Impact of Accuracy Problem Lists in Electronic Health Records on Correctness and Speed of Clinical Decision-making Performed by Dutch Healthcare Providers
The primary objective of this study is to determine whether patient records with complete, structured and up-to-date problem lists ('accurate problem lists'), result in better clinical decision-making, compared to patient records…
- Conditions
- Clinical Decision-Making, Decision Making, Computer-assisted, Medical Records, Problem-Oriented, Quality of Health Care
- Trial name
- ADAM's APPLE (NCT05657002)
- Testing
- patient A with accurate problem list, patient B with inaccurate problem list, patient A with inaccurate problem list
- Where
- Netherlands
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Eva Klappe
Evidence-Based Practices, CBT
A Hybrid Type 2 Trial of Trauma-Focused Cognitive Behavioral Therapy and a Pragmatic Individual-Level Implementation Strategy
This research project is a hybrid type 2 effectiveness-implementation trial that simultaneously examines (1) the effectiveness of a trauma-focused intervention for youth in the education sector and (2) the impact of a…
- Conditions
- Evidence-Based Practices, CBT, School Health Services, Trauma, Psychological
- Trial name
- NCT04451161
- Testing
- Beliefs and Attitudes for Successful Implementation in Schools (BASIS), Trauma-Focused Cognitive-Behavioral Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Washington
Clinical Practice, Nursing Education
The Effect of QR Code-Supported Perioperative Education Material Used in Clinical Practice
This study is planned as a randomized controlled trial to examine the effects of the use of QR (Quick Response) Code-supported materials prepared for perioperative care by nursing students during clinical practice on the…
- Conditions
- Clinical Practice, Nursing Education, Nursing Students, Evidence Based Nursing
- Trial name
- NCT06889077
- Testing
- QR Code Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Mental Health
Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments
This study will visit 4 community mental health clinics in Washington state and work with clinic staff to find out if staff are regularly evaluating clinical outcomes using questionnaires (which is also called measurement-based…
- Trial name
- NIMBLE (NCT05644756)
- Testing
- IMPACT Methods to Identify and Prioritize Determinants (Challenge I), Challenge and Match strategies to Prioritized Determinants (Challenge II)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases
There is an urgent need for stronger evidence to support recommendations for the role of sugars in diabetes and related cardiometabolic diseases.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Hypertension, Cardiovascular Diseases
- Trial name
- NCT02702375
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto