Clinical trials: Practice-based Evidence
Suicide Prevention
Adjunctive Team Enhanced Intervention to Improve Suicide Prevention Evidence-Based Practices in Primary Care
The purpose of the proposed study is to evaluate the feasibility and acceptability of a brief educational intervention (TEACH) that includes evidence-based strategies designed to improve task-specific teamwork and its impact (vs.
- Trial name
- NCT04606173
- Testing
- Team Education for Adopting Changes in Healthcare (TEACH)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Syracuse VA Medical Center
Suicide
Implementing Evidence Informed Practices in Schools to Address LGBTQ Adolescent Suicide
Reducing youth suicide in the U.S. is a national public health priority. Sexual and gender minority adolescents are at elevated risk for suicide. Safer school environments, however, can decrease this risk.
- Trial name
- RLAS (NCT02875535)
- Testing
- RLAS
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Emotional/Behavioral Function, Academic Performance
Efficacy of a Brief Intervention for School Clinicians (BRISC)
Research shows that the majority of all mental health (MH) treatment for children is delivered in schools. Unfortunately, however, school mental health (SMH) providers rarely use evidence-based approaches and are often poorly…
- Trial name
- BRISC (NCT03939208)
- Testing
- BRISC, SAU
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Washington
Evidence-Based Medicine, Physician-Nurse Relations
Advancing Research and Clinical Practice Through Close Collaboration (ARCC): A Pilot Test of an Intervention to Improve Evidence-Based Care and Patient Outcomes
The primary aim of this pilot study is to evaluate the effects of two variations of the ARCC Intervention Program on nursing processes and outcomes (job satisfaction, group cohesion, EBP knowledge, EBP implementation, EBP…
- Trial name
- NCT00635869
- Testing
- ARCC standard information, ARCC enhanced
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Myocardial Infarction (MI)
Patient Characteristics, Persistence to Treatment and Outcome Events in Patients Treated With Ticagrelor 60 mg After Myocardial Infarction in Real-world Clinical Practice
This is an observational study based on secondary data extracted from multiple register-based data sources in the US and Europe (Sweden, United Kingdom, Italy, Germany).
- Trial name
- ALETHEIA (NCT04568083)
- Where
- 6 sites in United States, Germany and 3 more
- Volunteers
- 7,035 people
- Sponsor
- AstraZeneca
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Diabetes Mellitus, Type 2
Efficacy of an Electronic System to Support Clinical Decisions in Adults With Type 2 Diabetes Mellitus.
To assess the efficacy of an electronic system to support clinical decisions based on an evidence-based clinical practice guide for metabolic control of adults with Type 2 Diabetes Mellitus through Clinical and cluster-randomized…
- Trial name
- OSI-DM (NCT03160196)
- Testing
- Clinical Decision Support System, Usual care based on clinical practice guideline
- Volunteers
- 1,768 people
- Sponsor
- Sanitas University
Evidence-Based Practice, Leadership
Online Training Course to Improve Evidence-based Leadership
The goal of this cluster clinical trial is to evaluate the effectiveness of online training course, targeted to unit leaders to improve staff's evidence-based skills (individual outcomes), EBP implementation (team-based…
- Trial name
- EVILEAD (NCT06886581)
- Testing
- Evidence-based leadership training
- Where
- Finland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Turku
Pleural Effusion
Clinical Implementation of the Use of Positive Pressure in Chest Drainage
Background: Scientific evidence appoints that the use of non-invasive positive airway pressure in pleural effusion drainage patients is associated with a reduction in these complications, as well as with other benefits.
- Trial name
- NCT03896672
- Testing
- Continuous Positive Airway Pressure
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Universidade Cidade de Sao Paulo
Dietary Intakes, Physical Activity
Implementing Modified Practices to Leverage Evidence for Movement, Engagement, and Nutrition Topics in Early Childcare and Education
The goal of this cluster-randomized, controlled trial is to learn if a professional development program for childcare educators, called the Boston Healthy Child Care Initiative, can help improve the nutritional quality of…
- Conditions
- Dietary Intakes, Physical Activity, Child Care, Early Education
- Trial name
- IMPLEMENT (NCT07874295)
- Testing
- Boston Healthy Child Care Initiative
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
ADHD
Web-based Professional Development for SMHPs in Evidence-Based Practices for Attention and Behavior Challenges
This study develops a web-based PD (CLS-R) to provide SSWs with remote training in EBPs for attention and behavior problems. CLS-R is designed to be usable, feasible, portable, accessible, and acceptable - ingredients which have…
- Trial name
- CLS-R (NCT05713331)
- Testing
- CLS-R
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Surveys and Questionnaires, Evaluation of Processes and Results
Survey Stroke Units in Argentina
Introduction Patients who receive care from stroke units are more likely to survive their stroke, become independent, and return home.
- Conditions
- Surveys and Questionnaires, Evaluation of Processes and Results, Healthcare, Evidence-based Clinical Practice
- Trial name
- NCT06623253
- Testing
- not aplicable
- Where
- Argentina
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospital de Rehabilitacion Manuel Rocca
Evidence-Based Nursing
EBP Educational Programme in Nursing Students' EBP Beliefs and Knowledge, and the Extent of Their EBP Implementation
Evidence-based practice (EBP) prevents unsafety/inefficiency and improves healthcare quality. However, EBP implementation and sustainment are challenging for healthcare organizations and providers considering gaps between…
- Trial name
- NCT03411668
- Testing
- EBP Educational Programme
- Where
- Portugal
- Volunteers
- 149 people
- Sponsor
- Escola Superior de Enfermagem de Coimbra
Pain, Incontinence, Urinary
Sumamos Excelencia 2022
There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices.
- Conditions
- Pain, Incontinence, Urinary, Obesity, Childhood, Breastfeeding
- Trial name
- NCT05466656
- Testing
- Continuous quality improvement cycle model
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Teresa Moreno Casbas
Substance Use Disorders, Chronic Mental Disorder
Phase II Motivational Interviewing: An Experiential Online Training Tool
Clinical social workers, doctors, outreach workers, and all other staff providing direct care to vulnerable populations face multiple challenges in obtaining and maintaining training and implementing evidence based practices in…
- Conditions
- Substance Use Disorders, Chronic Mental Disorder, HIV/AIDS
- Trial name
- NCT02264327
- Testing
- Motivational Interviewing Simulator (SIM), Motivational Interviewing eBook (eBook), Motivational Interviewing Training (MI Training)
- Where
- United States
- Volunteers
- 3,816 people
- Sponsor
- Center for Social Innovation, Massachusetts
Evidence-Based Practices, CBT
A Hybrid Type 2 Trial of Trauma-Focused Cognitive Behavioral Therapy and a Pragmatic Individual-Level Implementation Strategy
This research project is a hybrid type 2 effectiveness-implementation trial that simultaneously examines (1) the effectiveness of a trauma-focused intervention for youth in the education sector and (2) the impact of a…
- Conditions
- Evidence-Based Practices, CBT, School Health Services, Trauma, Psychological
- Trial name
- NCT04451161
- Testing
- Beliefs and Attitudes for Successful Implementation in Schools (BASIS), Trauma-Focused Cognitive-Behavioral Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dyslipidemia, Diabetes
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Fructose-containing sugars have been implicated in the epidemics of obesity, diabetes and related cardiometabolic disorders. This view is supported by lower quality evidence from ecological observations, animal models, and select…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT02716870
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Psychological Distress
Practice-Based Evidence in Psychotherapy in Ecuador
This is a naturalistic study implementing a routine outcome monitoring system to track clients' change and outcomes at the Centro de Psicología Aplicada (CPA) of the Universidad de Las Américas in Quito, Ecuador
- Trial name
- NCT05343741
- Testing
- Psychological Intervention
- Where
- Ecuador
- Volunteers
- 340 people
- Sponsor
- Universidad de las Americas - Quito
Diabetes, Prediabetes
Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome
Tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios and walnuts) are an important source of unsaturated fatty acids, vegetable protein, and fibre, as well as minerals, vitamins, and…
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01630980
- Testing
- Tree nuts
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Prostate Cancer, Evidence Based Medicine
A Cluster Package Intervention to Promote an Evidence-based Use of PSA-tests in General Practice
It is widely acknowledged that prostate specific antigen (PSA) testing can lead to false-positives, overdiagnosis and overtreatment of prostate cancer.
- Conditions
- Prostate Cancer, Evidence Based Medicine, Prostate Specific Antigen
- Trial name
- NCT06748456
- Testing
- Podcast, Cluster meeting, Hand-out material 1
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Copenhagen