Clinical trials: Practice-based Evidence
Evidence Based Practice
Facilitating Sustainment Through Implementation Feedback: The SIC Coaching Model
This study aims to test the impact of an empirically derived implementation strategy-under real-world conditions and across multiple child service systems-on successful adoption and sustainment of two evidence-based programs that…
- Trial name
- NCT03799302
- Testing
- SIC Coaching
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Oregon Social Learning Center
Information Dissemination, Evidence-Based Public Health
Disseminating Public Health Evidence to Support State Health Department Prevention of Cancer and Other Chronic Diseases
The purpose of this study is to identify and evaluate dissemination strategies to promote the uptake of evidence-based cancer and other chronic disease prevention among state-level public health practitioners.
- Trial name
- NCT01978054
- Testing
- Dissemination of public health knowledge
- Where
- United States
- Volunteers
- 1,703 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases
There is an urgent need for stronger evidence to support recommendations for the role of sugars in diabetes and related cardiometabolic diseases.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Hypertension, Cardiovascular Diseases
- Trial name
- NCT02702375
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dyslipidemia, Diabetes
Meta-analyses of Fructose and Cardiometabolic Risk
Diabetes and heart associations continue to discourage high intakes of dietary fructose, a constituent part of the sucrose molecule that is found in fruits and vegetables as a natural sugar and in some processed foods and…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01363791
- Testing
- Dietary fructose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Behavior Disorders
Evaluation of a Remote Training Strategy
An increasing number of schools in rural settings are employing the multi-tier positive behavioral interventions and supports (PBIS) framework to improve school-climate.
- Trial name
- NCT05039164
- Testing
- Coping Power Program (CPP), CBT for Anxiety Treatment in Schools (CATS), Check-in/Check-out (CI/CO)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection
Impact of Nurses' Behavior Change and Evidence-Based Practice Implementation on Quality Indicators in Intensive Care Units in Low- and Middle-Income Countries
Study title: Impact of nurses' behavior change and implementing evidence-based practice to improve quality indicators in intensive care units in low-and middle-income countries Background and Rationale: Quality care is crucial…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection, Pressure Ulcers (Hospital-acquired Pressure Injuries), Prolonged Intensive Care Unit Length of Stay
- Trial name
- NCT07397364
- Testing
- Evidence based practices bundles of care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Aging, Mild Cognitive Impairment
My Healthy Brain: Preserving and Promoting Brain Health Through Evidence-based Practices
The objective of this trial is to demonstrate early proof-of-concept for My Healthy Brain, an 8-week group program that directly targets multiple lifestyle factors associated with brain health and prevention of cognitive decline.
- Conditions
- Aging, Mild Cognitive Impairment, Dementia, Old Age; Dementia
- Trial name
- NCT04537728
- Testing
- My Healthy Brain Version 2
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Massachusetts General Hospital
Cardiovascular Disease, Diabetes
Meta-Analyses of Low-risk Lifestyle Behaviours and Patient Important Outcomes
Public health policy is universal in recommending the adoption of low risk low-risk lifestyle behaviors for health promotion and prevention of chronic or non-communicable diseases (NCDs).These behaviors generally include…
- Conditions
- Cardiovascular Disease, Diabetes, Cancer, Mortality
- Trial name
- NCT03234101
- Testing
- Low-risk lifestyle behaviours
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension
Improving Practice Patterns for the Treatment of Hypertension
To improve the quality of hypertension care in our facility, while concurrently, examining the relative contribution of each aspect of a multi-factorial intervention designed to improve hypertension care.
- Trial name
- NCT00265044
- Testing
- Provider Education, Hypertension Alert, Patient Education
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Migraine, Headache, Migraine
Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption
Observational analytic study with a prospective cohort design. Patients with episodic and chronic migraine that have responded to monoclonal antibodies (mAbs) versus calcitonin gene-related peptide (CGRP) or its receptor with…
- Trial name
- MADRE-MIA (NCT05232942)
- Testing
- Headache calendar completion
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Evidence Based Nursing, Leadership
Evidence-based Nursing Practice in Surgical Clinics
It is aimed to examine the leadership status and work environments of nurses working in surgical units during the integration of evidence-based practices into the institution.
- Trial name
- NCT06816472
- Where
- Turkey (Türkiye)
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Hand Hygiene Compliance
Tailor VHA HH Bundle for Acute Mental Health Care
Mental health settings are particularly vulnerable to outbreaks and transmission due to infectious pathogens like norovirus. This occurs since access to soap and water (sinks) is limited for safety reasons and alcohol hand rub is…
- Trial name
- NCT07607145
- Testing
- Tailored Hand Hygiene Bundle, Non-Alcohol Based Hand Sanitizer
- Where
- 4 sites in United States
- Volunteers
- 4 people
- Sponsor
- VA Office of Research and Development
Cocaine Use Disorder
Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project
The proposed work will investigate changes in brain signaling and cognitive functioning that support recovery from addiction, as well as use of pretreatment neurocognitive functioning to inform substance use treatment planning.
- Trial name
- WRAP (NCT03799341)
- Testing
- Prize-Based Contingency Management, Treatment As Usual Outpatient Substance Use Treatment
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Substance Abuse
Efficacy of Centervention-ATOD: An Implementation Tool for Dissemination of Evidence-based Programs for Substance Abuse
The pilot test of Centervention-ATOD, a customizable suite of online tools specifically designed to support quality implementation and sustainability of any ATOD-EBP within real-world service settings, will evaluate whether the…
- Trial name
- CV-ATOD (NCT03084406)
- Testing
- Centervention-ATOD (CV-ATOD)
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- 3-C Institute for Social Development
Cerebral Palsy
Evidence-based Physical Therapy in Children With Cerebral Palsy
The study aims to evaluate evidence-based practice behavior in usual care physical therapy in Flanders. Secondly, it aims to compare the effectiveness of a predefined physical therapy program based on evidence-based guidelines to…
- Trial name
- NCT02193386
- Testing
- No intervention, no follow-up, only registration, Intervention period
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Evidence Based Practice, Physical Therapy
EBP Confidence and Behavior Throughout PT Edu
This study aimed to describe changes in EBP confidence and behavior of students from four physical therapy education programs throughout their curriculum using the Evidence-Based Practice Confidence (EPIC) Scale and the…
- Conditions
- Evidence Based Practice, Physical Therapy, Education
- Trial name
- NCT05868018
- Testing
- Education
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
CRBSI - Catheter Related Bloodstream Infection, Evidence-based Nursing Practice
Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science
The goal of this type of study is to construct the continuous quality promotion project "ICU-NO CRBSI(Catheter-Related Bloodstream Infection , CRBSI)" based on improvement science, and to verify its effect in the prevention of…
- Conditions
- CRBSI - Catheter Related Bloodstream Infection, Evidence-based Nursing Practice, Central Venous Catheter Related Bloodstream Infection, Central Venous Catheter Associated Bloodstream Infection
- Trial name
- NCT06085690
- Testing
- evidence-based intervention Plan for the Prevention of CRBSI in ICU patients
- Where
- China
- Volunteers
- 8,050 people, healthy volunteers welcome
- Sponsor
- Fudan University
Body Weight, Obesity
Meta-analyses of Food Sources of Fructose-Containing Sugars and Obesity
Sugars have been implicated in the epidemics of overweight and obesity. This view is supported by lower quality evidence from ecological observations, animal models, and select human trials.
- Conditions
- Body Weight, Obesity, Overweight, Adiposity
- Trial name
- NCT02558920
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Atrial Fibrillation, Arterial Hypertension
Improvement Adherence to Clinical Practice Guidelines Using the Clinical Decision Support System in Patients With Hypertension and Atrial Fibrillation
The Clinical Decision Support Systems (CDSS) based on real clinical data and its own algorithms can help to make the right choice according to guidelines.
- Trial name
- INTELLECTII (NCT05367141)
- Testing
- CDSS ("MedicBK")
- Where
- Russia
- Volunteers
- 282 people
- Sponsor
- Samara Regional Cardiology Dispensary
Obesity, Pregnancy
Bringing NELIP for Obese Pregnant Women Into Clinical Practice
This is a pilot project in which investigators will recruit obese (pre-pregnancy BMI of ≥ 35 kg/m2) women from the newly developed "My Clinic" at London Health Sciences Centre as well as normal obstetrical care at London Health…
- Trial name
- NCT02155751
- Testing
- Nutrition Lifestyle Intervention Program (NLIP), Exercise Lifestyle Intervention Program (ELIP)
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's