Clinical trials: Pre Diabetic
Over Age 60, Prediabetes or Overweight
Curcumin Supplementation for the Improvement of Diabetes-related Outcomes
The goal of this clinical trial is to learn about, test, and compare health outcomes of curcumin supplementation (400 mg). Two primary hypotheses are: 1.
- Trial name
- CUR-T2D (NCT06984640)
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Prediabetes, Normal Plasma Glucose
The Effects of Nextida-GC and Whey Protein on Postprandial Glycemic and Insulinemic Responses When Given 30min Before, 10min Before or With a Standardized Breakfast Test-meal in Healthy Adults With and Without Prediabetes
The goals of this clinical trial are to learn if Nextida-GC (a peptide derived from collagen) will reduce postprandial glucose responses when taken 30 minutes before, 10 minutes before or with the first bite of a breakfast…
- Conditions
- Prediabetes, Normal Plasma Glucose, Normoglycemia
- Trial name
- NCT07174323
- Testing
- Peptide derived from collagen protein, Whey protein isolate
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- INQUIS Clinical Research
Type 2 Diabetes Mellitus
Prolactin Levels in Type 2 Diabetic Patients With Stage III Periodontitis
evaluate the role of prolactin hormone in the pathogenesis of periodontitis by assessing its local gingival levels and assess clinical parameters in patients who have type two diabetes
- Trial name
- prolactin (NCT06941246)
- Testing
- Non Surgical Periodontal Treatment, paper points, ELISA Kits
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Obesity, Pre Diabetes
Inulin and Acetate Production and Human Substrate Metabolism
Based on our hypothesis that orally administered resistant starch and inulin/beta glucan will be fermented into a SCFA pattern high in acetate and that this will lead to beneficial effects on human substrate and energy…
- Trial name
- NCT03711383
- Testing
- Inulin and Resistant Starch, Inulin
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Prediabetic State
Evaluation of a Community Health Program for the Prevention of Type 2 Diabetes and Other Cardio-metabolic Risk Factors in Adults: Districts of Barranquilla and Bogota, Colombia - January 2017 - December 2019
The main aim of this study is to evaluate the feasibility and effectiveness of a program for modifying lifestyles for diabetes prevention type 2 and control cardio-metabolic risk factors in adults with different categories of…
- Trial name
- PREDICOL (NCT03049839)
- Testing
- Intervention_ S, Intervention_ I, Intervention_ C
- Where
- 2 sites in Colombia
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Universidad del Norte
Pre-biabetes
Effects of Milk Probiotics Intervention on Blood Glucose Control Middle-aged and Elderly People With Pre-diabetes
This study aims to conduct a 8-week probiotics intervention involving for middle-aged and elderly individuals with pre-diabetes, assessing its impact on blood glucose control in comparison to placebo
- Trial name
- NCT06972524
- Testing
- a special probiotics from Mengniu Group, supplemented with milk powder, regular milk powder does not contain any additional supplementation, and the color, flavor, shape, taste, and weight are same with the probiotic milk powder
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Huilian Zhu
PreDiabetes, Nutrition
Zinc, Chromium, Vitamin C, and Copper Combination Supplement for Prediabetes Progression
Currently, the incidence of diabetes mellitus is increasing worldwide. People with prediabetes have higher risk to develop diabetes mellitus type 2.
- Trial name
- CHANGE (NCT04511468)
- Testing
- Zinc, Chromium, Vitamin C, and Copper Supplementation, Standard healthy lifestyle intervention
- Where
- Indonesia
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Continuous Glucose Monitoring, Prediabetic State
Effect of Real-time Continuous Glucose Monitoring System in Overweight or Obese Adults With Prediabetes
In Korea, 5 million adults aged 30 years or older have diabetes. The development and expansion of Korea's economy and society, has led to dramatic chances in people's lifestyle and diet habits, and an increase in life expectancy.
- Conditions
- Continuous Glucose Monitoring, Prediabetic State, Obesity
- Trial name
- NCT04099550
- Testing
- RT-CGM, SMBG
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Prediabetes, Obesity
Diabetes Prevention Program in Adults of the Yaqui Tribe of Hermosillo, Sonora at Risk of Diabetes
Diabetes is a major non communicable chronic diseases in the world. It occupies the fourth or fifth leading cause of death in most high-income countries and there is strong evidence that has epidemic proportions in many…
- Conditions
- Prediabetes, Obesity, Overweight
- Trial name
- NCT02899390
- Testing
- Lifestyle Intervention
- Where
- 3 sites in Mexico
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Centro de Investigación en Alimentación y Desarrollo A.C.
Healthy, PreDiabetes
Efficacy of Milk Product Supplemented With Bioactives in Lowering Post Meal Glucose Response
This is a monocentric, randomized controlled, open-label, 2x2 cross-over study. The main objective of the study is to Evaluate the efficacy of Nestle YIYANG TangLv milk powder in lowering the Post Prandial Glucose Response (PPGR)…
- Conditions
- Healthy, PreDiabetes, Adult, Asian
- Trial name
- NCT05570435
- Testing
- Blood collection
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Obese, Normal Body Weight
Cold Induced Changes in White Adipose
An adaptation to a cold environment is a tendency to generate heat within our body. Some of this heat comes from our fat tissue.
- Conditions
- Obese, Normal Body Weight, Prediabetes, Metabolic Syndrome
- Trial name
- NCT02596776
- Testing
- Fat biopsy, Propranolol and fat biopsy, heavy water and fat biopsy
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Philip Kern
Type 2 Diabetes, Prediabetes
Seum Bile Acid Profile in Type 2 Diabetes and Association Between Bile Cid Profile and Adipokine or Oxidative Stress
"The goal of this work is to critically test the hypothesis that there exists a different profile of bile acids (BAs) in patient with type 2 diabetes mellitus (T2DM) compared with normal controls.
- Conditions
- Type 2 Diabetes, Prediabetes, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome
- Trial name
- NCT02650830
- Where
- South Korea
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Occupational Stress, Gender Related Stress
Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women
The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and community resource navigation intervention improves psychological well-being, addresses non-biologic drivers of…
- Conditions
- Occupational Stress, Gender Related Stress, Social Isolation, Hypertension
- Trial name
- NCT07111026
- Testing
- Sisters for Heart Health, Basic intervention
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Emory University
PreDiabetes
Is Teaching People to be Self-compassionate Feasible and Acceptable for People Who Are Pre-diabetic
The investigators plan to examine the feasibility and acceptability of an online, two arm intervention ([self-compassion intervention + ideal care] versus [health information + ideal care]) designed to increase physical activity…
- Trial name
- NCT04402710
- Testing
- Self-compassion, Control Group
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Type 2 Diabetes, PreDiabetes
Bialystok Exercise Study in Diabetes
The "Bialystok Exercise Study in Diabetes" (BESD), is an exercise intervention study, conducted by the Department of Endocrinology, Diabetology and Internal Medicine and Clinical Research Centre of the Medical University of…
- Conditions
- Type 2 Diabetes, PreDiabetes, Overweight, Obesity
- Trial name
- BESD (NCT04634890)
- Testing
- Exercise intervention
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Prediabetes
Chinese Diabetes Prevention Program (Chinese DPP)
This study is being conducted in two phases. The first phase was a pilot implementation of the study protocol, which provided preliminary data from seeking funding for a larger scale trial.
- Trial name
- NCT02277509
- Testing
- Chinese DPP, Minimal Intervention Control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Prediabetic State, Insulin Resistance
Macronutrient Effects on Alzheimer's Disease (MEAL-2)
This study compares the effects of a one-month diet high in saturated fat (SF), glycemic index (GI), and salt (Na+) to a diet low in these nutritional parameters on memory and other cognitive functions, on MRI measures of brain…
- Conditions
- Prediabetic State, Insulin Resistance, Middle Age, Prehypertension
- Trial name
- MEAL-2 (NCT02463084)
- Testing
- Low Diet, High Diet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Prediabetes
Effect of a Nutritional Product Containing Carob Extract on Carbohydrate Metabolism in Glucose-intolerant Subjects
Randomized, controlled, double-blind clinical trial with two parallel arms based on the product consumed (experimental product and placebo product) and conducted at a single center, to measure the efficacy of the liquid NUTIFOOD…
- Trial name
- NUTIFOOD (NCT07420998)
- Testing
- Experimental Product, Control product
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Diabetes
Study of the Prevalence of Diabetes and Pre-diabetes in Réunion Island
In view of the new priority given to diabetes in Réunion and the implementation of an ambitious plan to combat the disease at regional level, which includes the identification and management of pre-diabetes, the need for…
- Trial name
- PREVADIABRUN (NCT06473584)
- Testing
- Diabetes detection
- Where
- Reunion
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Diabetes Mellitus, Type 2, PreDiabetes
Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial
The objective of this study is to compare two metabolically distinct diets, WFKD vs Med-Plus, in order to examine the potential benefits, and unintended consequences, of going beyond a focus on maximally avoiding added sugars and…
- Trial name
- NCT03810378
- Testing
- Mediterranean Diet (Med-Plus), Well-Formulated Ketogenic Diet (WFKD)
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University