Clinical trials: Pre Diabetic
Pre Diabetes, Insulin Resistance
Precision Diets for Diabetes Prevention
With this study the investigators want to understand the physiological differences for people developing pre-diabetes and diabetes.
- Conditions
- Pre Diabetes, Insulin Resistance, Diabetes Mellitus, Type 2
- Trial name
- NCT03919877
- Testing
- Dietary, Oral Food Challege
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sedentary Lifestyle, Physical Activity
A Mobile Based Diabetes Prevention Program
The goals of the study are to: 1. Assess effect sizes of our mDPP intervention on weight loss, physical activity, dietary intake, and fasting plasma glucose (FPG) levels from baseline to 5 months as compared to a control group.
- Conditions
- Sedentary Lifestyle, Physical Activity, Pre-Diabetic
- Trial name
- NCT01579292
- Testing
- Mobile phone based physical activity with intervention, Pedometer Only
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes and Healthy Control, FTO Gene Expression
Effects of Exercise Intervention and Confounding Factors on Type II Diabetic Muscles
The aim of the first year of this three-year plan is to analyze and compare the muscle quality of lower limb muscle (microcirculation, muscle performance and mechanical characteristics) and maximal aerobic exercise capacity in…
- Conditions
- Diabetes and Healthy Control, FTO Gene Expression, Aerobic Exercise Intervention or Home Exercise, Pre-training and Post-training
- Trial name
- NCT03869411
- Testing
- supervised aerobic exercise or home-based aerobic exercise
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy
To Identify Anytime Hyperglycaemia in Subjects With Normoglycaemia and Prediabetes
To test these hypotheses, The Investigators will recruit 100 overweight and obese adolescents with HbA1c ranging across the ADA classification spectrum from normal to prediabetes,(nearly 40:normoglycemi, 30: IFG, 30:1GT) measure…
- Trial name
- NCT05939895
- Testing
- Medtronic G3 sensor
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
PreDiabetes, Obesity, Childhood
Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance
The purpose of this study is to evaluate the longitudinal test performance of an array of conventional biomarkers of glycemia, including Hemoglobin A1c (HbA1c), and novel metabolomic biomarkers for identifying progression of…
- Trial name
- NCT05055219
- Where
- United States
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Prediabetic State
Effects of Whey Protein Pre-meals on Post-prandial Glucose
The aim of this project was to determine if an administration of either 10 g of whey protein isolate or 10 g of whey protein microgels 30 or 10 min before a standard meal could reduce postprandial glucose response in obese…
- Trial name
- NCT05112146
- Testing
- Whey protein isolate, Whey protein microgel, Water
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Normoglycemia, Prediabetes
Effect of Chronic Exposure to Nextida GC-B on Glycemic Control in Adults With Normoglycemia or Prediabetes
The goal of this clinical trial is to investigate the safety and efficacy of Nextida GC-B on glycemic control in adults with normoglycemia and prediabetes.
- Conditions
- Normoglycemia, Prediabetes, Glycemic Control
- Trial name
- NCT07149064
- Testing
- Nextida GC-B
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Type 2 Diabetes
Quantitative 18F-AV-133 PET Imaging in Subjects With Diabetes and Healthy Controls
To evaluate 18F-AV-133 imaging of the pancreas in patients with early type 2 diabetes, late type 2 diabetes, subjects with pre-diabetes and in healthy overweight/obese control subjects.
- Trial name
- NCT01710371
- Testing
- 18F-AV-133, 10% Arginine Hydrochloride-R-Gene 10
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
Prediabetes, Type 2 Diabetes
RISE Pediatric Medication Study
The RISE Pediatric Medication Study is a 2-arm, 4-center, clinical trial of children with prediabetes and early type 2 diabetes to address the hypothesis that aggressive glucose lowering will lead to recovery of beta-cell…
- Trial name
- RISE Peds (NCT01779375)
- Testing
- Metformin, Glargine
- Where
- 4 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- RISE Study Group
Sedentary Time, Cardiovascular Diseases
WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time
The purpose of this study is to determine the feasibility, acceptability, efficacy, and participant adherence in using home-based technologies and wearable devices and simple, practical strategies to reduce the negative impact…
- Conditions
- Sedentary Time, Cardiovascular Diseases, Prediabetes, Obesity
- Trial name
- NCT06963736
- Testing
- Blue light, Eating, Standing
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Prediabetes
Continuous Glucose Monitoring in Prediabetes With Health Education Videos Among Community Health Workers
The objective of this project is to deliver a behavior health education video series that combines wearable continuous glucose monitoring (CGM) with smartphone feedback and video clips generated by artificial intelligence (AI)…
- Trial name
- G2 (NCT06883812)
- Testing
- CGM
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- David S Black, PhD
Diabetes Mellitus, Pre Diabetes
Development and Validation of DM and Pre-DM Risk Prediction Model
Many DM and pre-DM remain undiagnosed. The aim is to develop and validate a risk prediction function to detect DM and pre-DM in Chinese adults aged 18-84 in primary care (PC). The objectives are to: 1.
- Trial name
- NCT04881383
- Testing
- OGTT and HbA1c
- Where
- Hong Kong
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pre-diabetes
Motivational Instant Messaging and E-diabetes Prevention Programme for High Risk of Type 2 Diabetes
The overall aim of this feasibility trial is to assess the effectiveness of a wearable technology and an e-diabetes prevention programme delivered via a smartphone application, including motivational messaging, in reducing weight…
- Trial name
- NCT02919397
- Testing
- Wearable technology, Diabetes Prevention Programme educational material, Motivational messaging
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King's College London
Pre Diabetes, Vascular Stiffness
Dietary Exchanges With Avocado and Mango in Pre-diabetes
The research is designed as a randomized, 2-arm, parallel, controlled, human clinical trial to investigate the effects of avocado and mango consumption for 8 weeks on indices of macro- and micro- vascular function in individuals…
- Conditions
- Pre Diabetes, Vascular Stiffness, Vascular Dilation, Cognitive Change
- Trial name
- AVMa (NCT05353790)
- Testing
- Meals + snacks: control, Meals + snacks: Avocado mango
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
PreDiabetes, Overweight and Obesity
Effect of a Probiotic on the Glycemic Profile and the Fecal Microbiota of Prediabetic Subjects (PREDIABETCARE)
According to the data from the Di@bet.es study, which is part of the National Diabetes Strategy, the prevalence of type 2 diabetes among Spanish population is 13.8%.
- Trial name
- PREDIABETCAR (NCT04863313)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Coronary Heart Disease, Susceptibility to, 5, Prediabetic State
Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease
The purpose of this study is to examine whether the use of genetic test information and/or health coaching in patient risk counseling for heart disease and diabetes affect health behaviors and health outcomes in active-duty Air…
- Trial name
- NCT01884545
- Testing
- Health coaching, Genetic risk counseling, Standard risk assessment
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Duke University
Pre-diabetes
More Health Less Diabetes
The "More Health, Less Diabetes" project is a hybrid randomized controlled trial to prevent type 2 diabetes in individuals at risk through structured exercise and lifestyle education.
- Trial name
- MHLD (NCT07079722)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease
Healthy Liver - Healthy Brain
People with liver disease report difficulties with attention and problem-solving skills. Diet plays an important role in the development of liver disease and/or pre-diabetes.
- Conditions
- Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease, NAFLD, Pre-diabetes
- Trial name
- NCT05216796
- Testing
- Diet Intervention
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Weight Loss, PreDiabetes
Diabetes Prevention Program to Treat Overweight and Obesity
The purpose of this study is to demonstrate the efficacy of the diabetes prevention program for the treatment of overweight and obesity within the community pharmacy setting.
- Trial name
- DPP-TOO (NCT05640869)
- Testing
- Modified Diabetes Prevention Program Curriculum
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Auburn University
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto