Clinical trials: Pre Eclampsia
Preeclampsia (PE)
Different Regimens of Magnesium Sulphate in Patients With Severe Preeclampsia
The goal of this observational study is to learn about the effects of the different drug regimens of magnesium sulphate in treatment of (severe pre-eclampsia).
- Trial name
- NCT06791668
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Ain Shams Maternity Hospital
Pre-Eclampsia, Hypertension in Pregnancy
Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida
To compare the incidence of preeclampsia in obese pregnant women (BMI greater than 30) with a singleton gestation at less than 20 weeks and either a history of preeclampsia in a prior pregnancy or stage I hypertension or…
- Conditions
- Pre-Eclampsia, Hypertension in Pregnancy, Obesity
- Trial name
- ASPREO (NCT03961360)
- Testing
- Aspirin 81 mg, Aspirin 162 mg
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- The University of Texas Health Science Center, Houston
Preeclampsia, Obstetric Labor Complications
Pravastatin to Prevent Preeclampsia
This study is a double-blind randomized placebo-controlled trial of 1,550 high-risk women to assess whether daily treatment with pravastatin administered early in pregnancy reduces the rate of a composite outcome of preeclampsia…
- Conditions
- Preeclampsia, Obstetric Labor Complications, Hypertension in Pregnancy
- Trial name
- Pravastatin (NCT03944512)
- Testing
- Pravastatin
- Where
- 12 sites in United States
- Volunteers
- 102 people
- Sponsor
- The George Washington University Biostatistics Center
Hypertension, Pregnancy-Induced
A Clinical Study of Fundus Findings in Toxaemia of Pregnancy
Toxemia of pregnancy is a recognized entity for over 2000 years with its known complications and fatality. Nowadays, a most accepted terminology for the following defined syndrome is "hypertensive disorders in pregnancy" given by…
- Trial name
- NCT03076619
- Testing
- clinical ophthalmoscopy
- Where
- India
- Volunteers
- 300 people
- Sponsor
- B. J. Medical College, Ahmedabad
Preeclampsia
Magnesium and Vanadium Levels in Preeclampsia
Introduction: Vanadium important pollutants produced from anthropogenic activities, has been suggested to be embryotoxic and fetotoxic in a lot of studies.
- Trial name
- V-Mg&PrE (NCT04387565)
- Testing
- magnesium and vanadium measurements and compare
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Cengiz Gokcek Women's and Children's Hospital
Puerperal Sepsis, Postpartum Hemorrhage
Assessing Childbirth-related Complications at the Community Level in Kenya
Kenya is one of the countries in sub-Saharan Africa that still experience high maternal mortality. For instance, in 2008/09 maternal mortality ratio was estimated to be 488/100,000 live births.
- Conditions
- Puerperal Sepsis, Postpartum Hemorrhage, Preeclampsia and Eclampsia, Retained Placenta, Without Hemorrhage
- Trial name
- NCT01665456
- Where
- Kenya
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- Wilson Liambila
Preeclampsia, Pregnancy
Aspirin Role for Preventing Clinical Risks Related to High Risk Pregnancy
Preeclampsia and its related consequences significantly contribute to maternal and neonatal morbidity and mortality, particularly in high-risk pregnancies.
- Trial name
- NCT07087067
- Testing
- Aspirin 75 mg
- Where
- Egypt
- Volunteers
- 87 people
- Sponsor
- Galala University
Preeclampsia
Mild Preeclampsia Near Term: Deliver or Deliberate?
Preeclampsia with new-onset hypertension and proteinuria is a pregnancy-specific disease that affects 5-7% of gestations usually after the 20th week.
- Trial name
- NCT00789919
- Testing
- Delivery of infant
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- University of Mississippi Medical Center
Pregnancy, Prolonged, Pre Eclampsia
Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor
PURPOSE: The purpose of this study is to determine the effectiveness of balloon dilatation (Foley) with vaginal misoprostol for cervical ripening and induction of labor.
- Conditions
- Pregnancy, Prolonged, Pre Eclampsia, Oligohydramnios
- Trial name
- NCT01140971
- Testing
- Misoprostol, Foley
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Municipal Hospital Vila Nova Cachoeirinha
Midazolam, Pre-eclampsia
Midazolam Efficacy/Safety in Pre-Eclamptic C-Section Sedation
This study will compare four different doses of midazolam (0 mg/kg, 0.01 mg/kg, 0.02 mg/kg, and 0.03 mg/kg) administered intravenously to women with pre-eclampsia undergoing cesarean section.
- Conditions
- Midazolam, Pre-eclampsia, Cesarean Section, Efficacy
- Trial name
- NCT07021521
- Testing
- 0 mg/kg Midazolam (Control Group), 0.01 mg/kg Midazolam Group, 0.02 mg/kg Midazolam Group
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Zhuji People's Hospital of Zhejiang Province
Pre-Eclampsia, Hypertension, Pregnancy-Induced
Remifentanil for General Anesthesia in Preeclamptics
The purpose of this study is to determine whether remifentanil use in preeclamptic patients may blunt hemodynamic response to intubation during general anesthesia for cesarean section.
- Conditions
- Pre-Eclampsia, Hypertension, Pregnancy-Induced, Pregnancy Complications
- Trial name
- NCT00567957
- Testing
- Remifentanil, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Pregnancy Complications, Pregnancy Outcome
BioThrax® (Anthrax) Vaccine in Pregnancy Registry
The purpose of this study is to determine if inadvertent receipt of the BioThrax vaccine during pregnancy is independently associated with adverse maternal, pregnancy, or infant health outcomes.
- Conditions
- Pregnancy Complications, Pregnancy Outcome, Congenital Abnormalities
- Trial name
- NCT01653392
- Testing
- Observational Intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Preeclampsia, Nursing Care
The Effect of Augmented Reality Based Training on Preeclampsia Case
However, no study has been found in the care of preeclampsia, which is highly effective on maternal and fetal health. Therefore, this study was planned to determine the effect of augmented reality-based training on the diagnosis…
- Conditions
- Preeclampsia, Nursing Care, Pregnancy, Augmented Reality
- Trial name
- preeclamside (NCT06730048)
- Testing
- Experimental Group
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Inonu University
Preeclampsia, Maternal
A Comparison of BNP Levels Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women
Primary Endpoint: Quantify the hemodynamic changes in preeclampsia using the non-invasive Nexfin device. Secondary Endpoint: Determine if measurable hemodynamic changes are statistically correlated with B-type natriuretic peptide…
- Conditions
- Preeclampsia, Maternal, Hypertension, Pregnancy
- Trial name
- NCT02527018
- Testing
- Sphygmomanometer
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Severe Preeclampsia
Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine
Pre-eclampsia (PE) is one of the most frequent pregnancy complications and is one of the main causes of maternal and fetal morbidity and mortality in its severe form.control of blood pressure is of crucial importance to avoid…
- Trial name
- NCT06265415
- Testing
- Labetalol, Nitroglycerine, Nifedipine
- Volunteers
- 60 people
- Sponsor
- Sohag University
Postpartum Preeclampsia
Efficacy of Diltiazem for the Control of Blood Pressure in Puerperal Patients With Severe Preeclampsia
Both preeclampsia and eclampsia are important health problems, being an important cause of maternal death in the world. Nifedipine has been used as the drug of choice for the treatment of hypertension during puerperium for more…
- Trial name
- NCT04222855
- Testing
- Diltiazem
- Volunteers
- 42 people
- Sponsor
- Hospital de la Mujer
Preeclampsia, Eclampsia
Vitamin D Supplementation Among Pregnant Women in Uganda for the Prevention of Hypertensive Disorders in Pregnancy, and Other Adverse Maternal and Foetal Outcomes
The goal of this randomised controlled trial is to investigate if vitamin D supplementation among pregnant women in Uganda prevents adverse maternal and foetal outcomes, with special emphasis on preeclampsia.
- Conditions
- Preeclampsia, Eclampsia, HELLP Syndrome
- Trial name
- MAMA (NCT07510568)
- Testing
- oral 2.000 IU vitamin D3 (cholecalciferol) daily, in addition to routine ANC supplementations
- Volunteers
- 1,980 people
- Sponsor
- St Mary's Hospital, Lacor
Preeclampsia
Detection of Epileptiform Activity in Severe Preeclampsia
The primary aim of this pilot study is to prospectively quantify epileptiform activity in a cohort of preeclamptic patients before and after intravenous magnesium administration.
- Trial name
- NCT03494517
- Testing
- Magnesium Sulfate
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- Pascal Vuilleumier
Preeclampsia
Combined Multi-marker Screening and Treatment With Aspirin for Pre-eclampsia Prevention
Phase III two arm double-blinded randomised controlled trial to examine the effect of prophylactic low-dose aspirin from the first-trimester of pregnancy in women at increased risk for PET on the incidence and severity of the…
- Trial name
- ASPRE (NCT02301780)
- Testing
- Aspirin
- Where
- Israel
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Hypertension Induced by Pregnancy, Pre-Eclampsia
Placental Growth and Adverse Pregnancy Outcomes
The purpose of this study to determine if measurement of maternal serum biomarkers and evaluation of the placenta by ultrasound can improve prediction of adverse pregnancy outcomes.
- Conditions
- Hypertension Induced by Pregnancy, Pre-Eclampsia, IUGR
- Trial name
- NCT01669525
- Where
- United States
- Volunteers
- 1,043 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania