Clinical trials: Pre Eclampsia
Postpartum Preeclampsia
Management of Postpartum Preeclampsia
The aim of this study is to assess the effect of a lower treatment threshold for antihypertensive medication and tighter blood pressure control, using remote blood pressure monitoring, on reducing Emergency Room visits for our…
- Trial name
- MOPP (NCT05775744)
- Testing
- Tight postpartum blood pressure control
- Where
- 2 sites in United States
- Volunteers
- 392 people
- Sponsor
- Rutgers, The State University of New Jersey
Hypertension in Pregnancy, Preeclampsia
Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy
This is a pragmatic, open-label, randomised control trial of three oral anti-hypertensive regimens for women with severe hypertension in pregnancy.
- Trial name
- NCT01912677
- Testing
- Nifedipine, Labetalol, Methyldopa
- Where
- 2 sites in India
- Volunteers
- 894 people
- Sponsor
- Gynuity Health Projects
Preeclampsia
Racial Differences: Nitric Oxide(NO) and Endothelin-1(ET-1) in Preeclampsia (PreE)
The goal of this study is to examine the activation of markers of endothelial and cardiovascular dysfunctions, from women with high-risk pregnancies.
- Trial name
- NCT00653809
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Mississippi Medical Center
Preeclampsia
Serum LncRNAs as Early Potential Biomarkers for the Prediction of Preeclampsia
To identify lncRNAs differentially expressed at early stages of gestation in the serum of pregnant women, who later developed severe preeclampsia (sPE) in the third trimester of pregnancy compared to women with normal pregnancy .
- Trial name
- NCT03903393
- Where
- China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Preeclampsia
Proof-of-Concept Trial on Selective Removal of sFlt-1 in Pregnant Women With Preeclampsia Via Apheresis
This clinical investigation is a medical device trial to examine the safety and efficacy of TheraSorb sFlt-1 adsorber treatment of pregnant patients with preeclampsia.
- Trial name
- SAVE (NCT02923206)
- Testing
- TheraSorb sFlt-1 adsorber
- Where
- 4 sites in Germany, United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Miltenyi Biomedicine GmbH
Preeclampsia, Stress, Psychological
Stress Reduction in Formerly Preeclamptic Women; Sofa or Sports
The goal of this clinical trial is to evaluate stress and cardiovascular risk factors in women with preeclampsia in the medical history.
- Conditions
- Preeclampsia, Stress, Psychological, Stress, Physiological, Sports Physical Therapy
- Trial name
- SOS (NCT06402604)
- Testing
- Aerobic exercise training, Mindfulness Based Stress Reduction training
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Hypertensive Disorder of Pregnancy, Sleep Apnea, Obstructive
Positive Airway Pressure Treatment of Obstructive Sleep-disordered Breathing in Hypertensive Disorders of Pregnancy
The purpose of this study is to conduct a pilot randomized, controlled trial to evaluate the feasibility and obtain pilot outcome data for a subsequent definitive trial evaluating the effects of postitive airway pressure (PAP)…
- Trial name
- NCT03309826
- Testing
- Positive Airway Pressure, Nasal Dilator Strip
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Dr John Kimoff
Hypertension, Pre-eclampsia
Clinical Validation of the Blood Pressure Measuring Device Withings BPM Pro 2 in Pregnancy and Pre-Eclampsia
The aim of the study is to assess the accuracy of the automatic oscillometric BP measuring device at the brachial level, the WITHINGS BPM Pro 2, in pregnancy and pre-eclampsia
- Trial name
- WIHYP-PW (NCT07595016)
- Testing
- Blood pressure measurement
- Where
- Armenia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Withings
Pre-Eclampsia
Association Between Vitamin D Deficiency and Preeclampsia: A Case Control Study
To find out if lower levels of vitamin D is more prevalent in preeclamptic women
- Trial name
- NCT02677233
- Volunteers
- 90 people
- Sponsor
- Ain Shams Maternity Hospital
Gestational Complications, Body Mass Index
Antenatal Body Shape Index and Pregnancy Complications
Background/aim: Gestational diabetes (GDM), gestational hypertension (GHT) and preeclampsia are common complications of pregnancy.
- Conditions
- Gestational Complications, Body Mass Index, Waist Circumference, Gestational Hypertension
- Trial name
- NCT07022158
- Testing
- The patients participating in the study were between 6 and 16 weeks of pregnancy. Height, body weight, and waist circumference were measured at the first antenatal visit at 2 weeks.
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Antithrombin III Deficiency
Atenativ Effect on Uterine Blood Flow and Preeclampsia
The study will be an open controlled pilot study of 6 patients with early-onset severe preeclampsia. Patients will receive Atenativ in addition to conventional therapy The patients will be followed up within the study until three…
- Trial name
- NCT02278575
- Testing
- Atenativ
- Where
- Sweden
- Sponsor
- Vastra Gotaland Region
Preeclampsia, Heart Failure Preserved Ejection Fraction
Exercise Testing After Preeclampsia
Though cardiovascular disease (CVD) is the leading cause of mortality in women, traditional epidemiology in this area has focused on later life, when cardiometabolic risk has already exacted a cumulative toll on the vascular…
- Conditions
- Preeclampsia, Heart Failure Preserved Ejection Fraction, Hypertension
- Trial name
- NCT06741436
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pre-Eclampsia, Pregnancy Related
Study of Nicotinamide in Early Onset Preeclampsia
Phase II Study of 2.5 gm of nicotinamide, given daily in 3 divided doses, to measure effect on maternal blood pressure in women with early onset preeclampsia and to determine peak and trough levels of nicotinamide.
- Trial name
- NCT03419364
- Testing
- nicotinamide
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of North Carolina, Chapel Hill
Preeclampsia
Mechanistic Underpinnings of Preeclampsia
Preeclampsia is a dreadful disease with significant morbidity and mortality. Despite decades of research, we still need a proper diagnostic test or therapeutic option to treat this disorder.
- Trial name
- MUP (NCT06567899)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Anemia in Pregnancy, Pre-eclampsia
A Retrospective Analysis of Neevo® and NeevoDHA® Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
This study is a multi-site, retrospective chart review to determine the effect of Neevo® or NeevoDHA® (with higher folate and B12) versus standard prenatal vitamins on hemoglobin (Hgb) levels in pregnant women throughout the…
- Trial name
- NCT01193192
- Testing
- Neevo®, Prenatal vitamins
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pamlab, L.L.C.
Hypertension, Pregnancy-Induced, Hypertension
Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines
To better understand postpartum blood pressure changes, the investigators are proposing a study to monitor blood pressure after delivery in 100 patients who the investigators expect to have normal blood pressure (i.e.
- Conditions
- Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication
- Trial name
- NCT06576544
- Testing
- BP Watch
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Diego
Hypertension in Pregnancy, Gestational Diabetes
Reshaping Postpartum Follow-up
The aim of this study is to evaluate the impact of personalized postpartum follow-up cards on completion of postpartum health related tasks. The intervention will consist of a card given to patients at time of discharge.
- Conditions
- Hypertension in Pregnancy, Gestational Diabetes, Cervical Dysplasia
- Trial name
- NCT06054841
- Testing
- Postpartum follow up card, Control
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Pregnancy Induced Hypertension, Superimposed Preeclampsia
Phase I Study of Nicotinamide for Early Onset Preeclampsia
This is a Phase I study of vitamin B3-amide (nicotinamide) dietary supplementation in pregnant women with early onset preeclampsia.
- Conditions
- Pregnancy Induced Hypertension, Superimposed Preeclampsia, Hypertension
- Trial name
- NCT02213094
- Testing
- Nicotinamide 500 mg, Nicotinamide 1000 mg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Pre-eclampsia, Obesity
ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes
Obesity is a growing problem in East London and every other woman who enters pregnancy is obese or overweight. In addition to obesity, other metabolic risk factors such as raised lipids, high blood pressure and diabetes increase…
- Conditions
- Pre-eclampsia, Obesity, Raised Lipids, High Blood Pressure
- Trial name
- ESTEEM (NCT02218931)
- Testing
- Targeted ESTEEM diet, Non-randomised cohort
- Where
- United Kingdom
- Volunteers
- 3,442 people
- Sponsor
- Queen Mary University of London
Pre-Eclampsia
Safety and Efficacy of Twelve Hours Duration of MgSO4 in the Treatment of Eclampsia in Low Resource Setting in Sudan
the investigators assume that magnesium sulphate for treating eclampsia can be safely reduced from 24 hours to shorter duration of therapeutic anticonvulsant effect for 12 hours.
- Trial name
- NCT03112551
- Testing
- Adminstration of magnesium Sulphate for treatment of eclampsia
- Where
- Sudan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gadarif University