Clinical trials: Pre-Diabetic
Type 2 Diabetes, Pre-Diabetes
Power-Up: An Effectiveness Trial of the Diabetes Prevention Program
The goal of this study is to address the risk of diabetes among men by creating a Diabetes Prevention Program (DPP) tailored to men.
- Trial name
- Power-Up (NCT04104243)
- Testing
- Men-Tailored DPP (Power-Up)
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- Albert Einstein College of Medicine
Type 1 Diabetes, Preeclampsia
Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes
This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in…
- Conditions
- Type 1 Diabetes, Preeclampsia, Preeclampsia (PE) Risk
- Trial name
- PREEATH-T1D (NCT07479329)
- Where
- 2 sites in Spain
- Volunteers
- 1,300 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Pre-diabetes, Pre-diabetic State
VA|PREVENTION: Randomized Controlled Trial of a Person-Centred Digital Intervention to Prevent Diabetes in High-Risk Adults
The goal of this clinical trial is to help prevent the development of type 2 diabetes (T2D) in adults who are at risk. The study will test a digital intervention called VA|PREVENTION, a web application designed to support and…
- Trial name
- VA|PREVENTION (NCT07021144)
- Testing
- VA|PREVENTION web application (digital intervention), Type 2 Diabetes Guidebook
- Where
- 16 sites in Portugal
- Volunteers
- 180 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Pre Diabetic
Effects of Intermittent Fasting Variations on Metabolic, Inflammatory, and Nutrigenomic Profiles in Prediabetes: A Randomized Controlled Trial
Prediabetes is a metabolic condition associated with increased risk of type 2 diabetes and cardiovascular disease. Intermittent fasting (IF) has emerged as a potential dietary intervention to improve metabolic health, yet…
- Trial name
- NCT07408791
- Testing
- Diet
- Where
- Indonesia
- Volunteers
- 120 people
- Sponsor
- DINA KEUMALA SARI
Obesity and Overweight, Pre-diabetic
Targeted Precision Nutrition Strategy To Prevent Chronic Metabolic Diseases
Nutrition is very important to keep blood sugar levels balanced. If blood sugar levels are too high, it can lead to diseases such as cardiovascular disease and type 2 diabetes (T2DM).
- Conditions
- Obesity and Overweight, Pre-diabetic, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- PRECINUT (NCT06923644)
- Testing
- Optimal Metabotype-specific diet, Sub-optimal diet
- Where
- 2 sites in Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pre Diabetes, Diabetes (DM)
Preventing Diabetes: Impact of an EMR-Based Intervention for Enhanced Pre-Diabetes Management in Primary Care
The goal of this study is to find out if adding electronic medical record (EMR) prompts helps prevent people with pre-diabetes from developing diabetes. It will also look at how these prompts affect doctor and patient behaviors.
- Trial name
- NCT07252700
- Testing
- Electronic Medical Record-Based Clinical Decision Support
- Where
- Singapore
- Volunteers
- 6,000 people
- Sponsor
- Lynette Goh
Screening, Pre Diabetic
Prediabetes in End Stage Renal Disease on Dialysis
Prediabetes is a highly prevalent condition, affecting about one-third of adults in the United States Patients with prediabetes have an increased risk for diabetes, with 2% to 10% progressing to diabetes each yea Although…
- Conditions
- Screening, Pre Diabetic, Chronic Renal Failure (CRF), Dialysis Patients
- Trial name
- NCT07337083
- Where
- 2 sites in Egypt
- Volunteers
- 262 people
- Sponsor
- Sohag University
Weight Loss Trial, Cardiometabolic Syndrome
Peau o le Vasa: Analysis of the Efficacy and Feasibility of the PILI Lifestyle Program (PLP) + Social Determinants of Health (SDOH) Intervention and Adaptation of SDOH Measures Pilot Study
Native Hawaiians and Pacific Islanders (NHPIs) are defined as the descendants of the original peoples of Polynesia (e.g., Hawai'i, Sāmoa, and Tonga), Melanesia (e.g., Fiji), and Micronesia (e.g., Guam, Chuuk, and Marshall…
- Conditions
- Weight Loss Trial, Cardiometabolic Syndrome, Hypertension, Dyslipidemia
- Trial name
- NCT06471595
- Testing
- Partnership for Improving Lifestyle Intervention (PILI) Lifestyle Program + Social Determinants of Health (SDOH) Component
- Where
- 4 sites in United States
- Volunteers
- 242 people
- Sponsor
- University of Hawaii
Type 2 Diabetes Mellitus, Pre-diabetes
Acute Effects of Cold-induced Shivering on 24-hour the Glucose Profile in Metabolically Compromised Populations
Type 2 Diabetes Mellitus (T2DM) and its associated comorbidities pose a major health concern worldwide. Although lifestyle strategies, such as exercise and diet-induced weight loss are effective interventions to counteract the…
- Trial name
- SHIVER (NCT05576025)
- Testing
- Lifestyle intervention (cold exposure)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Anemia of Pregnancy, Gestational Diabetes
SMART Health Pregnancy 2 - Intervention to Reduce Anaemia and Cardiometabolic Risk During Pregnancy and in the First Year Following Birth
The goal of this clinical trial is to determine if a complex intervention called SMARThealth Pregnancy can improve the detection and management of high-risk conditions during pregnancy and in the first year after birth in women…
- Conditions
- Anemia of Pregnancy, Gestational Diabetes, Gestational Hypertension, Pre-Eclampsia
- Trial name
- NCT05752955
- Testing
- SMARThealth Pregnancy
- Where
- India
- Volunteers
- 3,446 people
- Sponsor
- The George Institute
Preeclampsia, Preeclampsia (PE)
Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia
This study's primary purpose is to determine the relationship between aspirin metabolism and markers of metabolic dysfunction among patients at risk for preeclampsia.
- Conditions
- Preeclampsia, Preeclampsia (PE), Preeclampsia (PE) Risk, Obesity and Obesity-related Medical Conditions
- Trial name
- RAMP (NCT06802861)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Diabetes (DM), Pre Diabetes
FastForward: A Prospective Analysis of Long-term Fasting and Subsequent Food Reintroduction in Humans
This study explores what happens in the body and wellbeing during and after a period of long-term fasting. At the Buchinger Wilhelmi Clinic, participants follow a medically supervised fasting program lasting five or more days…
- Conditions
- Diabetes (DM), Pre Diabetes, Overweight (BMI > 25)
- Trial name
- FastForward (NCT07155993)
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Buchinger Wilhelmi Development & Holding GmbH
Type 1 Diabetes (T1D), Registry
UK Islet Autoantibody Registry
Type 1 diabetes (T1D) is a life-long condition where the immune system destroys part of the body (the pancreas) which makes the chemical, insulin. Insulin is needed to control blood sugar levels.
- Conditions
- Type 1 Diabetes (T1D), Registry, Pre-diabetes, Screening
- Trial name
- UKIAb Registry (NCT07125365)
- Where
- United Kingdom
- Volunteers
- 350 people
- Sponsor
- University of Oxford
Heart Diseases, Diabetes Mellitus, Type 2
Behavior Change Intervention for Cardiovascular Risk Reduction Among People Experiencing Homelessness
This single-arm trial of the Cardiovascular Risk Reduction Among People Experiencing Homelessness (CV-Homes) intervention alone (n=8) will test the perception and feasibility of anticipated study procedures.
- Conditions
- Heart Diseases, Diabetes Mellitus, Type 2, Pre-diabetes, Hypertension
- Trial name
- CV-Homes (NCT06025721)
- Testing
- Cardiovascular Risk Homeless Support
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Katherine Vickery
Pre-diabetes
More Health Less Diabetes
The "More Health, Less Diabetes" project is a hybrid randomized controlled trial to prevent type 2 diabetes in individuals at risk through structured exercise and lifestyle education.
- Trial name
- MHLD (NCT07079722)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Gestational Diabetes Mellitus, Pre-diabetes
A Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus
Our goal is to test whether shared decision making for diabetes prevention can help women with a history of gestational diabetes mellitus (GDM) who are at high risk of developing type 2 diabetes (T2DM) increase weight loss and…
- Conditions
- Gestational Diabetes Mellitus, Pre-diabetes, Diabetes Mellitus, Type 2
- Trial name
- NCT04897945
- Testing
- Shared decision-making for diabetes prevention
- Where
- 2 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gestational Complications, Body Mass Index
Antenatal Body Shape Index and Pregnancy Complications
Background/aim: Gestational diabetes (GDM), gestational hypertension (GHT) and preeclampsia are common complications of pregnancy.
- Conditions
- Gestational Complications, Body Mass Index, Waist Circumference, Gestational Hypertension
- Trial name
- NCT07022158
- Testing
- The patients participating in the study were between 6 and 16 weeks of pregnancy. Height, body weight, and waist circumference were measured at the first antenatal visit at 2 weeks.
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Diabetes, Pre Diabetes
Diabetes Prevention and Education
Type 2 diabetes mellitus is one of the fastest growing public health problems in developed and developing countries and imposes a large financial burden on health-care systems.
- Conditions
- Diabetes, Pre Diabetes, Fatty Liver, Body Weight Changes
- Trial name
- NCT05769127
- Testing
- Diabetes Prevention Program (DPP), Diabetes Self-Management Training (DSMT)
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Type 2 Diabetes, Muscular Atrophy
Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes
The purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest in older adults with pre-diabetes and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise
- Trial name
- RECOVER (NCT04057677)
- Testing
- Bed Rest Intervention, Exercise Program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Breastfeeding, Breastfeeding Initiation
Birth & Breastfeeding Support Study
The goal of this observational study is to learn about the effects of birth practices such as cesarean section and vacuum assisted birth and diseases such as gestational diabetes and preeclampsia on exclusive breastfeeding.
- Conditions
- Breastfeeding, Breastfeeding Initiation, Breastfeeding Duration, Birth
- Trial name
- BABSS (NCT06844019)
- Where
- Denmark
- Volunteers
- 1,628 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital