Clinical trials: Pre-Term
Premature, Thermoregulation
Delaying First Bathing and Skin Barrier Function on Infant
It is still unknown when the first bath should be done in premature newborns. Investigators think that delaying the time of the first bath compared to the time in the clinic will show some positive changes in preterm newborns.
- Trial name
- TEWL (NCT04231799)
- Testing
- Bathing
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Pregnancy, Stillbirth
Zambian Preterm Birth Prevention Study
This prospective non-intervention cohort study will enroll women in the first or early second trimester of pregnancy and follow them through delivery (or end of pregnancy) and 1 year postpartum.
- Conditions
- Pregnancy, Stillbirth, Preterm Birth
- Trial name
- ZAPPS (NCT02738892)
- Where
- 2 sites in Zambia
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Preterm Labor Without Delivery, Pregnancy Preterm
The Treatment of Magnesium Sulfate and Nifedipine in Preterm Labor Threat
Comparison of the effects of Nifedipine and MgSO4 therapies on maternal and fetal blood flow.
- Trial name
- MgSO4 (NCT05520021)
- Testing
- Nifedipine, Magnesium sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Psoriasis, Coronary Artery Disease
Premature Coronary Artery Disease (CAD) in Severe Psoriasis
The purpose of this study is to compare the prevalence and severity of CAD (coronary artery disease) in patients with and without severe psoriasis, otherwise matched for cardiovascular risk factors.
- Trial name
- NCT00893126
- Testing
- CCTA Scan (Coronary CT Angiogram)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pain
Breast Feeding Analgesia in Preterm Infants
The purpose of this study is to compare the effects of mothers' breastfeeding with the effects of pacifier sucking on preterm infant biobehavioural responses during and immediately after a painful procedure Hypothesis: 1.
- Trial name
- NCT00175409
- Testing
- Blood collection
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy
An Observational Study to Assess Respiratory Syncytial Virus (RSV) Respiratory Events Among Premature Infants
The primary objective is to assess the burden of respiratory disease in outpatient settings among 32 to 35 weeks' gestational age (wGA) infants in the USA who did not receive RSV prophylaxis during the infants' first RSV season.
- Trial name
- NCT00983606
- Where
- 222 sites in United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Premature Infants
Infant Formula Supplemented With a Special Fat Formulation for Premature Infants Following Discharge From Hospital
The purpose of this study is to compare the efficacy and nutritional suitability of 2 infant formulas supplemented with different levels of LCPUFA, for premature infants following discharge from Hospital.
- Trial name
- NCT01140243
- Testing
- LCPUFA
- Where
- 2 sites in Israel
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Materna Laboratories
Infection, Bacterial, Infection, Fungal
Point-of-care Tests for Bacterial Vaginosis and Candidosis
Vaginal infection in early pregnancy is associated with an increased risk of spontaneous preterm delivery and late miscarriage. Most studies presume that vaginal infections are responsible for up to 40% of preterm birth.
- Conditions
- Infection, Bacterial, Infection, Fungal, Preterm Birth
- Trial name
- NCT04287504
- Testing
- SavvyCheck Vaginal Yeast Test, OSOM BVBLUE Test
- Where
- Austria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Ventricular Premature Complexes
CBT for Premature Ventricular Contractions
The purpose of the present interdisciplinary research program is to develop and evaluate a disease-specific cognitive behavior therapy (CBT) protocol to increase quality of life (QoL) and reduce symptom burden in patients with…
- Trial name
- PVC-CBT (NCT05087238)
- Testing
- CBT
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Bronchopulmonary Dysplasia (BPD), Hypertension, Pulmonary
Predictors of Pulmonary Hypertension Risk in Premature Infants With Bronchopulmonary Dysplasia
A lung condition called bronchopulmonary dysplasia (BPD) is a major cause of poor outcomes and death for premature infants. Infants with BPD are also at high risk for pulmonary hypertension (PH)-an important contributor to their…
- Trial name
- NCT01516398
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Episiotomy; Complications, Episiotomy Extended by Laceration
Outcomes Following Pre-marking of Episiotomy Location
To compare short- and long-term outcomes of women following episiotomy during the second stage of labor, following marking of episiotomy location during the first stage of labor with those of women who underwent episiotomy…
- Conditions
- Episiotomy; Complications, Episiotomy Extended by Laceration, Episiotomy Infection
- Trial name
- NCT04719533
- Testing
- Pre-marking of episiotomy location
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sharon Davidesko MD
Pre-diabetes
Short-term Health Effects of Wild Blueberry Juice Consumption
Researchers at the University of Prince Edward Island want to learn about the health effects of wild blueberry juice.
- Trial name
- NCT02139878
- Testing
- Wild blueberry juice
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Prince Edward Island
Genomic and Metabolomic Variations, Preterm Birth
Effects of Genomic and Metabolomic Variations of Choline on Risk of Preterm Birth and Clinical Outcomes in Preterms
The incidence of preterm birth increases annually. Premature delivery has become the leading cause of neonatal illness and death.
- Conditions
- Genomic and Metabolomic Variations, Preterm Birth, Total Parenteral Nutrition
- Trial name
- NCT02841813
- Testing
- No intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Premature Ovarian Insufficiency, Metabolomics
Effect and Mechanism of Jiajian Guishen Formulation on Premature Ovarian Insufficiency Based on Metabolomics
1. Identify differential metabolites in POI patients. 2. Analysis of differential metabolites and their involved mechanism pathways.
- Conditions
- Premature Ovarian Insufficiency, Metabolomics, Traditional Chinese Medicine, Mechanism
- Trial name
- JJGS and POI (NCT06102655)
- Testing
- Jiajian Guishen Formulation
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Shi Yun
Preterm Delivery
Neonatal Outcome by Reason for Delivery
To determine the rate of Composite Neonatal Morbidity for very preterm babies delivered secondary to preterm labor (PTL) vs. prelabor rupture of membranes (PROM).
- Trial name
- NCT01818518
- Where
- 10 sites in United States
- Volunteers
- 995 people, healthy volunteers welcome
- Sponsor
- Obstetrix Medical Group
Fetal Membranes, Premature Rupture
Myometrial Thickness as a Predictor for the Latency Interval in PPROM
100 women divided into 3 groups: Group I: included 50 women with preterm premature rupture of membranes (PPROM, n=50) with gestational age from 24 to 34 weeks.
- Trial name
- NCT02380560
- Testing
- Ultrasonographic examination
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteopenia Of Prematurity
A Preliminary Study of Bone Density in Neonates
The study is to measure how dense or solid the infant's bones are using a new ultrasound machine and how that density changes over time.
- Trial name
- NCT00631397
- Testing
- Ultrasound machine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Breastfeeding, Exclusive, Position
Facilitated Tucking Position's Effect on Comfort and Breastfeeding
This study investigated the effect of facilitated tucking in the early postpartum period on preterm neonate comfort and breastfeeding performance.
- Conditions
- Breastfeeding, Exclusive, Position, Preterm Birth
- Trial name
- NCT04704180
- Testing
- Facilitation Tuchking Position
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Threaten Preterm, Prethrem Labour
The Effects of Adjunctive Therapy With Vaginal Tablets Lactobacillus Acidophilus and a Low Dose Estriol (Gynoflor®) to Prolong Pregnancy Time in Preterm Labor, A Randomized Controlled Trial
The study aim to study The Adjunctive therapy with vaginal tablets containing Lactobacillus acidophilus KS400 and low-dose Estriol (Gynoflor®) in addition to standard tocolytic treatment administered once daily for 6 days…
- Conditions
- Threaten Preterm, Prethrem Labour, Bacterial Vaginitis
- Trial name
- NCT07344064
- Testing
- Gynoflor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Neutropenia
Late Neutropenia in VLBW Preterm Babies
There are rare reports regarding late neutropenua in very low birth weight preterm infants. The investigators wish to characterize it among our population, and assess its consequenses and the postnatal menagement of the infants.
- Trial name
- NCT04217811
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
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