Clinical trials: Pre-diabetic
Type2 Diabetes, PreDiabetes
Secular Trends in the Prevalence of Diabetes in India
Series of epidemiological studies have been carried out by the research team since 1988 studying the changes in the prevalence of type 2 diabetes, prediabetes and associated risk factors.
- Trial name
- STRiDE-I (NCT03490136)
- Where
- India
- Volunteers
- 9,848 people, healthy volunteers welcome
- Sponsor
- India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals
PreDiabetes, Aging
A Double-Blind, Placebo-Controlled Trial of Anti-Aging, Pro-Autophagy Effects of Metformin in Adults With Prediabetes
The goal of this pilot and feasibility study is to investigate the effects of a short course of metformin therapy on a surrogate marker of cellular senescence and autophagy among adult patients with prediabetes.
- Trial name
- NCT03309007
- Testing
- Metformin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of New Mexico
Normal Weight, Overweight and Obesity
Effect Cinnamon Spice on Postprandial Glucose and Insulin Responses
The objective of the proposed study is to investigate the effect of cinnamon on the postprandial glycemic response to a high glycemic index meal in normal and overweight/obese prediabetic subjects
- Trial name
- CINNI (NCT04686552)
- Testing
- cinnamon
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Diabetic Retinopathy
Augmenting Referral Pathway to Improve Uptake of Retinal Services by Diabetic Patients
Reiyukai Eiko Masunaga Eye Hospital (REMEH) is a non-profitable organization. Retina services were resumed from October 2019. Until this retinal service started, it has been mostly cataract-focused.
- Trial name
- NCT04829084
- Testing
- Pre-post educational intervention
- Where
- Nepal
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Seva Foundation
Metabolic Syndrome, Diabetes Mellitus, Type 2
Induced and Controlled Dietary Ketosis as a Regulator of Obesity and Metabolic Syndrome Pathologies
Original research article entitled Induced and Controlled Dietary Ketosis as a Regulator of Obesity and Metabolic Syndrome by Madeline Gibas for consideration for publication in a clinical journal.
- Conditions
- Metabolic Syndrome, Diabetes Mellitus, Type 2, Pre Diabetes
- Trial name
- NCT03047447
- Testing
- Dietary Ketosis: Regulator of Obesity and Metabolic Syndrome
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bristlecone Behavioral Health, Inc.
Kidney Failure, Chronic, Prediabetic State
The Effect of Liraglutide in Patients With Prediabetes and Kidney Failure
The present study will examine the effects of liraglutide treatment during 26 weeks on several cardiovascular risk factors in patients with prediabetes and end-stage renal disease (ESRD).
- Trial name
- LiRA2 (NCT02284230)
- Testing
- Liraglutide
- Where
- Denmark
- Sponsor
- Bo Feldt-Rasmussen
Pre Diabetes
Supplementation of Eriocitrin in Intestinal Microbiota
Pre-diabetes is characterized by high plasma concentration of glucose and glycated hemoglobin and is the main risk factor for the development of type 2 diabetes.
- Trial name
- NCT03925909
- Testing
- Eriocitrin
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- São Paulo State University
Elderly, Pre-diabetic
The Effect of Oral Carnitine Supplementation on MRS-derived Mitochondrial Function
This is a longitudinal study supported by Pfizer and is a collaboration between DMPI (Duke Molecular Physiology Institute) and DIAL (Duke Image Acquisition Laboratory) to measure the effects of acute exercise on carnitine and…
- Trial name
- NCT02124590
- Testing
- Acute Exercise
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Duke University
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Risk-informed Shared-decision Making Engagement Strategy for Patients With Prediabetes
The goal of this clinical trial is to learn if knowing risk for diabetes can help adult patients with prediabetes take steps to get care and prevent diabetes.
- Trial name
- RISE (NCT07553325)
- Testing
- Risk Informed Shared Decision-Making Strategy (RISE), Low Touch Messaging Strategy (LTM)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Johns Hopkins University
Healthy, Pre-diabetic
The Effect of Acute Lysine Administration on α-aminoadipic Acid
This study aims to assess the effect and breakdown of lysine administration, specifically examining whether it leads to increased plasma 2-AAA in healthy humans.
- Trial name
- NCT02756117
- Testing
- L-Lysine, Normal (0.9%) Saline
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Pharmacists' Delivery of Education to Prevent Diabetes in the New Orleans Hospitality Industry
This is a one-year pilot study focused on prediabetes among hospitality workers in New Orleans, Louisiana. The project will assess prediabetes rates among the target population, evaluate the impact of pharmacist led lifestyle…
- Conditions
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetic State &Amp; High Risk Individuals on the Basis of Diabetes Risk Score
- Trial name
- NCT07451314
- Testing
- Linkage to Care, Educational, Healthy Lifestyle Tools
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Prediabetes
Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans
This nested pilot Randomized Clinical Trial will determine whether the Diabetes Prevention Program (DPP) enhanced with evidence-based sleep health and time restricted eating interventions ("DPP++") is more effective than the DPP…
- Trial name
- NCT07450118
- Testing
- National Diabetes Prevention Program (DPP), Sleep Health Digital Application, Time-Restricted Eating (TRE)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Delaware
Prediabetes, Dietary Self-Management
Continuous Glucose Monitoring and Dietary Self-Management in Adults in Namwon
This study will test whether adding a continuous glucose monitoring (CGM) device, which shows personal glucose patterns, improves dietary self-management over the first 6 weeks.
- Conditions
- Prediabetes, Dietary Self-Management, Diabetes Mellitus, Type 2
- Trial name
- NCT07890740
- Testing
- Continuous Glucose Monitoring With Application-Based Biofeedback, Common Standardized Education and Behavioral Goal Setting, Common Digital Health Program and Basic Health Counseling
- Where
- 4 sites in South Korea
- Volunteers
- 860 people
- Sponsor
- Ji-Yeob Choi
Impaired Fasting Glucose, Pre Diabetes
Dietary Interventions in Prediabetes
Assessment of glucose metabolism and liver fat after 12 week dietary intervention in pre diabetes subjects. Subjects will be randomized to either high fat (olive oil supplemented),high carb/high fiber (beans supplemented) and…
- Conditions
- Impaired Fasting Glucose, Pre Diabetes, Liver Fat
- Trial name
- NCT01729078
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Mayo Clinic
Pre Diabetes, Diabetes
Comparing Diabetes Prevention Programs
The purpose of this study is to compare the effectiveness and costs of two programs,the Diabetes Prevention Program and the community-developed Healthy Living Program, delivered in an primary care practice.
- Trial name
- NCT01409889
- Testing
- Diabetes Prevention Program, Healthy Living Program
- Where
- 4 sites in United States
- Volunteers
- 92 people
- Sponsor
- University of Rochester
Prediabetes
Blood Sugar Take Care and Glucose Metabolism
This prospective international clinical trial is a two-arm, double-blind, randomized, placebo-controlled, parallel-group, multicenter study. 112 prediabetic subjects will be randomized to Blood Sugar Take Care or placebo.
- Trial name
- NCT01554020
- Testing
- Blood Sugar Take Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NewChapter, Inc.
Healthy, Prediabetic State (IGT)
Noninvasive Transcutaneous Glucometer Development
The objective of this study is to assist in the development of a noninvasive device for the accurate measurement of blood glucose levels.
- Conditions
- Healthy, Prediabetic State (IGT), Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NCT01168076
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- InLight Solutions
Pre-diabetes, Diabetes
RCT of SMS for Drivers With Pre-DM
The purpose of this study is to prevent the professional drivers from pre-diabetes to diabetes.
- Trial name
- NCT01556880
- Testing
- Short Message Service (SMS)
- Where
- 3 sites in Hong Kong
- Volunteers
- 104 people
- Sponsor
- The University of Hong Kong
Type 2 Diabetes, Cardiovascular Diseases
Pistachios Blood Sugar Control, Heart and Gut Health
A two-period randomized crossover study will be conducted to evaluate the effect of nighttime pistachio consumption (i.e., after dinner and before sleep) on fasting blood sugar levels, longer-term blood sugar control, and risk…
- Trial name
- NCT04056208
- Testing
- Pistachio, Usual care
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy
Glycemic and Insulinemic Index Determination of Two Products: Fructilight® and A Fruit Fructo-Oligosaccharides in Sweet Matrix
The aim of the study is to determine glycemic and insulinemic index of 2 sweet syrups : FructiLight® and fruit Fructo-oligosaccharides in sweet matrix compared to glucose.
- Trial name
- IGNUT (NCT01343797)
- Testing
- Glycemic and insulinemic index tests of a fruit fructose syrup and a fruit fructo-oligosaccharid syrup
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CRITT Bio-Industries
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