Clinical trials: Pre-diabetic State
Obesity, Adolescent, PreDiabetes
Unsweetened Sparkling Water and Changes in Sweetness Perception in Adolescents
The study design is a prospective observational study in adolescents who are at risk for developing Type 2 Diabetes (T2D), to evaluate the effectiveness of sparkling water to reduce dietary intake of added sugars and thereby…
- Trial name
- NCT05966870
- Testing
- Unsweetened flavored sparkling water
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Indiana University
Obesity, Cardiovascular Risk Factor
Coordinating Pragmatic Primary Care Population Management for Obesity
The C3PO pilot and feasibility study uses a rigorous, mixed-method research design to provide information needed to refine and implement a technology-mediated primary care outreach intervention approach before conducting a larger…
- Trial name
- C3PO (NCT03998046)
- Testing
- Outreach Support for Weight Loss Goal Setting and Self-Weighing, Outreach Decision Support to Encourage Linkages to Intensive Community Lifestyle Interventions, Adaptive Tailoring of Information Delivery and Intensity of Primary Care Outreach Support
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Prediabetes
Development of Smart Food /Nutraceutical Solutions Dedicated to Cardiometabolic Disorders in Ageing
Describe the anthropometric measurements and informations relating to body composition, blood chemistry tests, blood glucose monitoring, and dietary habits of the volunteers participating in the study before and after taking…
- Trial name
- NutriAge (NCT07817290)
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Diabetes Mellitus, Prediabetic State
Effect of Pravastatin in the Subjects With Prediabetes or Early Diabetes
An increased risk of incident diabetes with statin therapy have been reported in several studies. However, it is not recommended to limit the use of statin for this reason since the absolute risk increase was small, and the…
- Trial name
- NCT02754739
- Testing
- Pravastatin, Nutritional education only
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Samsung Medical Center
Prediabetes
Profile and Regulatory Network of Exercise in Improving Metabolic Phenotypes of Patients With Prediabetes
This study is a single-arm, self-control, single-center study to investigate the molecular mechanism under exercise improving metabolism of patients with prediabetes.
- Trial name
- NCT06633575
- Testing
- exercise intervention
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Zhongshan Hospital
Obesity, Prediabetes
Effect of Aerobic Exercise Program on Blood Glucose Level and Quality of Life in Pre-diabetic Overweight/Obese Adolescents
PURPOSE: The study aims to: Investigate the effect of the designed aerobic exercise program on the blood glucose level (fasting blood glucose and HbA1C) in overweight/ obese pre-diabetic adolescents.
- Trial name
- NCT06756425
- Testing
- aerobic exercise program, nutritional health awareness sessions
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pediatric Obesity, Prediabetic State
Health Outcomes of Teens Participating in Summer Employment Immersion Programs
This study is a collaboration between investigators and two community partners: a youth employment program and an urban farm. The community partners hire 300+ adolescents for summer jobs at various organizations.
- Trial name
- NCT02886208
- Testing
- Measurement
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Indiana University
Metabolic Syndrome, Insulin Resistance
Mechanisms Underlying Metabolic Syndrome in Obesity
The purpose of this study is to better understand the link between obesity and diabetes or pre-diabetes.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Prediabetes
- Trial name
- NCT00579813
- Testing
- Pioglitazone
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Philip Kern
Type 2 Diabetes
Dynamic Responsiveness of Insulin Secretory Parameters To Sitagliptin and Glimeperide Administration in Type 2 DM
A multi-year clinical study to improve tools for measuring the function of insulin-producing beta cells in people with type 2 diabetes mellitus.
- Trial name
- NCT02443922
- Testing
- Glimepiride, Sitagliptin, Metformin
- Volunteers
- 100 people
- Sponsor
- Foundation for the National Institutes of Health
Periodontitis Stage III, Periodontitis Stage IV
Blood Glucose Screening in Patients With Advanced Periodontits: the Role of Specialist Periodontal Care in Identifying Hyperglycaemia and Supporting Patient Centered Treatment
Periodontitis is a chronic inflammatory disease and individuals with advanced periodontitis have an increased risk of hyperglycaemia.
- Conditions
- Periodontitis Stage III, Periodontitis Stage IV, Diabetes (DM), Prediabetes
- Trial name
- NCT07426224
- Testing
- Selective screening of blood glucose/HbA1c
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Folktandvården Stockholms län AB
PreDiabetes
Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics
The goal of this clinical trial is to compare efficacy and safety of metformin versus apple cider vinegar in prediabetics . The main question[s] it aims to answer are: Efficacy of metformin versus apple cider vinegar in…
- Trial name
- BUHSCK (NCT05759442)
- Testing
- Metformin Hydrochloride (HCL), Apple cider vinegar
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Bahria University
Prediabetes
ForgIng New Paths to Prevent DIabeTes (FINDIT)
This study will evaluate the effects of screening for type 2 diabetes mellitus (T2DM) and brief counseling about screening test results on weight and key health behaviors among Veterans with risk factors for T2DM.
- Trial name
- FINDIT (NCT02747108)
- Testing
- Blood Test Group Intervention, Brochure Group Intervention
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prediabetic State, Dysglycemia
Clinical Trial to Evaluate the Efficacy and Safety of the Probiotic Strains Limosilactocillus Reuteri DSM 32910 and Lacticaseibacillus Paracasei DSM 32851 on Glucose Homeostatis in Prediabetic Adults
The aim of this international, randomized, parallel arms, double-blind, placebo-controlled clinical trial is to investigate the safety and efficacy of a combination of the two Lactobacillus strains (NZ-GHMH-01) on glucose and…
- Trial name
- NOVOGLUCOSE (NCT04767789)
- Testing
- NZ-GHMH-01
- Where
- 8 sites in France, Romania and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
PreDiabetes, Older Adults
Vivo Prediabetes Study: Online, Live, and Interactive Strength Training for Older Adults With Prediabetes
This research trial studies the effect of an online, live and interactive strength training program on physical function and strength in older adults with prediabetes.
- Conditions
- PreDiabetes, Older Adults, Muscle Loss, Muscle Weakness
- Trial name
- NCT05497960
- Testing
- Vivo workout
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eric Levian
Prediabetic State
Instrument Development of Screening Prediabetes Patients
It will be more effective if we can work on the primary prevention for the high risk groups of diabetes and prediabetes such as the early detection.
- Trial name
- NCT00308646
- Volunteers
- 3,000 people
- Sponsor
- China Medical University Hospital
Diabetes, Prediabetes
Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome
Tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios and walnuts) are an important source of unsaturated fatty acids, vegetable protein, and fibre, as well as minerals, vitamins, and…
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01630980
- Testing
- Tree nuts
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Over Age 60, Prediabetes or Overweight
Curcumin Supplementation for the Improvement of Diabetes-related Outcomes
The goal of this clinical trial is to learn about, test, and compare health outcomes of curcumin supplementation (400 mg). Two primary hypotheses are: 1.
- Trial name
- CUR-T2D (NCT06984640)
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
PreDiabetes, Abdominal Obesity
Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus
This multicenter, double-blinded, randomized controlled trial aims to evaluate the effect of berberine on preventing cardiovascular disease and diabetes mellitus among individuals with high cardiometabolic risk in China.
- Conditions
- PreDiabetes, Abdominal Obesity, Hypertension, Dyslipidemias
- Trial name
- ABCD (NCT05749874)
- Testing
- Berberine plus lifestyle intervention
- Where
- China
- Volunteers
- 2,024 people
- Sponsor
- China National Center for Cardiovascular Diseases
Type 2 Diabetes
Characterization of the Variability of Insulin Secretory Parameters in the Meal Tolerance and the Maximal Stimulation Tests of Subjects With Type 2 Diabetes Mellitus
A multi-year clinical study to improve tools for measuring the function of insulin-producing beta cells in people with type 2 diabetes mellitus.
- Trial name
- NCT01663220
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Foundation for the National Institutes of Health
Diabetes, Obesity & Overweight
Exercise and Tissue-Specific Insulin Sensitivity in South Asian and Nordic Women With Previous Gestational Diabetes
South Asian women have a high risk of developing type 2 diabetes, and the risk is particularly high after gestational diabetes. This study examined whether eight weeks of supervised vigorous exercise improves insulin sensitivity…
- Trial name
- DIASA-Ex (NCT07843082)
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 43 people
- Sponsor
- Oslo University Hospital