Clinical trials: Pre-diabetic State
Healthy
To Identify Anytime Hyperglycaemia in Subjects With Normoglycaemia and Prediabetes
To test these hypotheses, The Investigators will recruit 100 overweight and obese adolescents with HbA1c ranging across the ADA classification spectrum from normal to prediabetes,(nearly 40:normoglycemi, 30: IFG, 30:1GT) measure…
- Trial name
- NCT05939895
- Testing
- Medtronic G3 sensor
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Type 2 Diabetes, Prediabetes
A Mindfulness-based Intervention for Adolescents With Prediabetes or Type 2 Diabetes
The purpose of this study is to conduct a mindfulness-based intervention for adolescents referred for prediabetes or type 2 diabetes treatment to 1) evaluate feasibility and acceptability of the intervention for future research…
- Trial name
- L2BT2D (NCT07270900)
- Testing
- Mindfulness Based Group
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Prediabetes
Anti-diabetic Effects of Persimmon Leaf Extract
The investigators performed a 8-week, randomized, double-blind, placebo-controlled crossover human trial to evaluate the efficacy and safety of persimmon leaf extract on blood glucose.
- Trial name
- NCT02706821
- Testing
- Persimmon leaf extract
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
PreDiabetes
Social Prescription and Lifestyles Modification to Reduce Glycemia in People With Prediabetes (PREDIBAL)
This study aims to evaluate the effectiveness and cost-utility of an intervention based on the social prescription of health assets to modify lifestyles and reduce blood glucose values in prediabetic patients in primary care…
- Trial name
- PREDIBAL (NCT04328363)
- Testing
- Intervention
- Volunteers
- 232 people
- Sponsor
- University of the Balearic Islands
Hyperglycaemia (Non Diabetic), Prediabetes
Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults
We will be directly comparing a high-quality protein diet composed primarily of lean pork loin (PORK) to a lower-quality plant-based protein diet (PLANT) in individuals with prediabetes on muscle and whole-body protein turnover…
- Trial name
- PORK (NCT06025292)
- Testing
- Lean Pork vs Plant-Based Protein
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arkansas
Type 2 Diabetes Mellitus (T2DM), Hypertension (HTN)
Cohort Study of Metabolic Disease and Hypertension
The goal of this observational study is to learn how type 2 diabetes and high blood pressure develop over time in adults in Mexico.
- Trial name
- NCT07577063
- Testing
- Observational Study
- Where
- Mexico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
PreDiabetes, NAFLD
Effects of Almonds in Glucose-intolerant Adults (AGAMEMNON)
Tree nuts - such as almonds - contribute to beneficial effects of the Mediterranean diet on risk for cardiovascular events, type 2 diabetes, dyslipidemia, hypertension, inflammation and non-alcoholic fatty liver disease.
- Trial name
- AGAMEMNON (NCT06413069)
- Testing
- Raw whole almonds
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Charite University, Berlin, Germany
Hyperglycemias, Prediabetes
Efficacy of the pA1c®HI Postbiotic in Metabolic Regulation in Healthy Individuals With Hyperglycemia
This study will evaluate the effects of pA1c®HI, a heat-inactivated postbiotic derived from the bacterium Pediococcus acidilactici, on blood glucose regulation and other aspects of metabolic health in adults with elevated blood…
- Trial name
- CR2027 (NCT07903870)
- Testing
- Postbiotic
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genbioma Aplicaciones SL
Gestational Diabetes Mellitus (GDM)
Screening for Dysglycemia During Postpartum Period in Women With GDM
Gestational diabetes mellitus (GDM) is one of the most common clinical conditions in pregnancy, with an increasing incidence due to the rise in overweight women and the postponement of motherhood.
- Trial name
- NCT07489456
- Testing
- Whatsapp message
- Where
- Brazil
- Volunteers
- 182 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetes Mellitus, Type 2, Obesity
The Glycemic Effect of Added Sugar on Bake Beans
To investigate the effect of added sugar to bake beans on glycemic and insulinemic response.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, PreDiabetes
- Trial name
- GIF (NCT03868683)
- Testing
- Glucose Reference 1, Glucose Reference 2, Glucose reference 3
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Prediabetes
The Avoiding Diabetes Thru Action Plan Targeting Pilot Randomized Control Trial
The goal of this randomized control trial is to study the impact of an electronic health record embedded tool's ability to facilitate shared provider-patient goal setting to promote lifestyle behavior change and prevent diabetes…
- Trial name
- ADAPT (NCT01473654)
- Testing
- ADAPT tool
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston University
Prediabetes, Type 2 Diabetes
Effects of Dried Whole Fruits on Metabolism in Diabetes
Diabetes becomes epidemic in worldwide countries. Diabetes Canada indicated that 30% of adults in Manitoba are diabetes or prediabetes. Nine out of ten diabetic patients are type 2 diabetes (T2D).
- Trial name
- NCT07354386
- Testing
- Freeze dried whole Saskatoon berry, Freeze dried apple slice bulk
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- University of Manitoba
Prediabetes
Early Precise Identification and Intervention Strategies for Individuals at High Risk of Prediabetes
Prediabetes significantly increases the risk of developing diabetes, cardiovascular and cerebrovascular diseases, tumors, and dementia.
- Trial name
- NCT07386756
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Diabetes Mellitus, Type 2, PreDiabetes
T-UP: Engaging Vulnerable Students in Diabetes Prevention
The goal of this study is to enhance reach and uptake of diabetes prevention among young adults, with a focus on recruiting underserved and high-need students who face additional challenges, including food and financial…
- Trial name
- NCT06385015
- Testing
- Tailored DPP Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Prediabetes, Cardiovascular Disease
Cardioprotective Activities Of Whole Eggs On Vascular Endothelial Function In Prediabetic Adults
Cardiovascular disease (CVD) is largely a lifestyle-related condition that is the #1 killer of adults in the United States. Our work is aimed at understanding how short-term increases in blood sugar, like those that accompany…
- Trial name
- NCT02364570
- Testing
- Glucose (100g), Glucose (75g), Whole Eggs
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Prediabetic State, Insulin Resistance
United for Health: Type 2 Diabetes Prevention in Latino Teens
This study pilots the feasibility and acceptability of a family-based lifestyle intervention for decreasing diabetes risk called "Salud sin Barreras" (meaning, "Health without Barriers") delivered in the community to Latino teens…
- Conditions
- Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress
- Trial name
- UNITED (NCT03527641)
- Testing
- CookingMatters, Parent Education, Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Colorado State University
Prediabetes (Impaired Fasting Glucose and/or Impaired Glucose Tolerance)
Effect of Rubus Occidentalis Extract on Plasma Glucose Levels in Subject With Prediabetes
The purpose of this study is to determine whether Rubus occidentalis extract could improve fasting or postprandial serum glucose levels, and related metabolic markers among patients with prediabetes (impaired fasting glucose…
- Trial name
- NCT01964703
- Testing
- Rubus occidentalis extract
- Volunteers
- 29 people
- Sponsor
- Korea University Anam Hospital
Prediabetic State, Impaired Fasting Glucose
Evaluation of the Safety and Efficacy of SGLT2 Inhibitors in Pre-diabetic Patients
Pre-diabetes is a state characterized by subclinical impairment in glycemic variables that is intermediate between normal glucose tolerance (NGT) and diabetes.
- Conditions
- Prediabetic State, Impaired Fasting Glucose, Impaired Glucose Tolerance
- Trial name
- NCT05914857
- Testing
- Dapagliflozin 10mg Tab, lifestyle interventions
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yangjin
Prediabetes, Type 2 Diabetes
Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes
Given the data on the active ingredients of Totum-63, this research aims to evaluate the effect of its chronic consumption (24 weeks) on glucose and lipid homeostasis and especially on fasting plasma glucose in volunteers with…
- Conditions
- Prediabetes, Type 2 Diabetes, Hypertriglyceridemia, Obesity
- Trial name
- TOTUM-63 TWO (NCT02868177)
- Testing
- Totum-63
- Where
- 6 sites in France, Ireland and 2 more
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Prediabetic State, Insulin Resistance
Effect of Linagliptin + Metformin vs Metformin Alone in Patients With Prediabetes
Type 2 diabetes is a worldwide epidemic disease, and preventive strategies are needed to face this health problem. The goal of this clinical trial is to evaluate the effect of linagliptin + metformin vs metformin alone on…
- Trial name
- PRELLIM (NCT03004612)
- Testing
- Linagliptin + metformin, Metformin
- Where
- Mexico
- Volunteers
- 144 people
- Sponsor
- Universidad de Guanajuato