Clinical trials: Pre-dialysis
Pre-Dialysis
Phase 2 Study of Darbepoetin Alfa Extended Dosing
Multicenter, open label single arm study in which 140 subjects with CRI who are currently receiving SC darbepoetin alfa once every other week will receive darbepoetin alfa once every 4 weeks for 24 weeks.
- Trial name
- NCT00527215
- Testing
- darbepoetin alfa
- Volunteers
- 98 people
- Sponsor
- Amgen
Kidney Failure,Chronic
Comparison of Oxidative Stress and Insulin Resistance Before and After Using Physioneal in Peritoneal Dialysis Patients
Patients affected by end-stage renal disease (ESRD) are subjected to enhanced oxidative stress, as a result of reduced anti-oxidant systems and increased pro-oxidant activity.
- Trial name
- NCT00172211
- Testing
- Physioneal
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Anemia
A Study of Subcutaneous C.E.R.A. for the Treatment of Anemia in Pre-Dialysis Patients.
This single arm study will assess the efficacy, safety and tolerability of subcutaneous C.E.R.A. for correction of anemia and maintenance of hemoglobin levels in patients with chronic kidney disease who are not on dialysis and…
- Trial name
- NCT00576628
- Testing
- methoxy polyethylene glycol-epoetin beta [C.E.R.A.]
- Where
- 19 sites in Russia
- Volunteers
- 133 people
- Sponsor
- Hoffmann-La Roche
Oral Disease, Chronic Kidney Diseases
Oral Findings in Chronic Kidney Disease
The patients with chronic kidney disease suffer from many oral problems affecting the quality of life. The aim of our study is to assess their oral health to provide the proper management and increase their awareness
- Trial name
- NCT03082365
- Volunteers
- 225 people
- Sponsor
- Maryam Ahmed Essam Abdel Salam
Anemia of Chronic Kidney Disease
Study of HEMAX PFS Versus EPREX/ ERYPO® in Predialysis Chronic Kidney Disease
Phase III, multicenter, randomized, open, controlled clinical trial. A study designed as phase III, in 120 patients with chronic renal failure in the pre-dialysis stage, evaluate efficacy and safety of Hemax PFS® (PFS: prefilled…
- Trial name
- NCT04036253
- Testing
- Erythropoietin alfa
- Where
- 11 sites in Argentina, Paraguay
- Volunteers
- 43 people
- Sponsor
- Bio Sidus SA
Kidney Failure, Chronic, Cognitive Dysfunction
Emotion and Cognitive Function and Brain Imaging Change in HD Patients
1. Observe the influence of entering hemodialysis treatment on the emotional and cognitive functions of ESRD patients. 2. Observe the influence of entering hemodialysis treatment on the brain structure imaging of ESRD patients.
- Conditions
- Kidney Failure, Chronic, Cognitive Dysfunction, Magnetic Resonance Imaging
- Trial name
- NCT05137470
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Chronic Kidney Disease, End Stage Renal Disease
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden.
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Hemodialysis, Peritoneal Dialysis
- Trial name
- TEACH-VET (NCT04064086)
- Testing
- Comprehensive Pre-ESRD Patient Education (CPE), Provision of the freely available resources for Kidney Disease Education
- Where
- United States
- Volunteers
- 656 people
- Sponsor
- VA Office of Research and Development
Delayed Function of Renal Transplant, Primary Nonfunction of Renal Transplant
The Effects of Pre-transplant Dialysis Modality on Post-transplant Events
This is a prospective, multicenter, comparative, parallel-group, observational study. There will be 2 cohorts according to pre-transplant dialysis modality (hemodialysis or peritoneal dialysis).
- Conditions
- Delayed Function of Renal Transplant, Primary Nonfunction of Renal Transplant, Acute Rejection of Renal Transplant
- Trial name
- PDMP (NCT01513707)
- Where
- South Korea
- Volunteers
- 1,040 people
- Sponsor
- Ha Young Oh
Renal Dialysis
Mannitol Use During Cadaveric Kidney Transplantation
We propose a placebo controlled randomized study on the use of mannitol as an agent to protect against delayed graft function, during the surgical procedure of kidney transplantation from a cadaver.
- Trial name
- NCT04705402
- Testing
- Mannitol, Saline
- Volunteers
- 32 people
- Sponsor
- Rabin Medical Center
Kidney Diseases, Metabolic Acidosis
Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5
This clinical trial aims to investigate and test the effect of an acid/base diet in chronic kidney disease (CKD) patients, CKD stage 4 and 5.
- Conditions
- Kidney Diseases, Metabolic Acidosis, Renal Insufficiency, CKD
- Trial name
- REMA-CKD (NCT05784389)
- Testing
- Low PRAL
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Renal Disease
Monocentric Retrospective Cohort Study of the Impact of Advanced Nursing Practice on the Follow-up of the End Stage Chronic Renal Disease Patient
With regard to the fields of competence of advanced practice defined by the Order of October 22, 2021 amending the Order of July 18, 2018 on the system of studies for the State diploma of advanced practice nurse mentioning renal…
- Trial name
- IPASIRC (NCT06036264)
- Testing
- Collected of Datas, semi-structured interview
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Chronic Kidney Disease
Flipped Classroom Approach in Continuous Ambulatory Peritoneal Dialysis Training
The goal of this single-blinded randomized controlled trial is to evaluate the effectiveness of an educational intervention for patient self-management and successful renal replacement therapy in Chronic Kidney Disease (CKD)…
- Trial name
- FCCAPD (NCT06221228)
- Testing
- Audio-visual assisted Flipped Classroom (FC) CAPD Training Programme
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Hyperkalemia
A Study to Test Whether ZS (Sodium Zirconium Cyclosilicate) Can Reduce the Incidence of Increased Blood Potassium Levels Among Dialized Patients.
The purpose of this study is to evaluate the efficacy of ZS in the treatment of hyperkalemia in patients on hemodialysis.
- Trial name
- DIALIZE (NCT03303521)
- Testing
- Sodium Zirconium Cyclosilicate (ZS)
- Where
- 53 sites in United States, Japan and 2 more
- Volunteers
- 196 people
- Sponsor
- AstraZeneca
Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4
Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis Chronic Kidney Disease (CKD) Patients
Aims: The investigators' primary objective is to assess both perceived and actual disease knowledge in local pre-dialysis Chronic Kidney Disease (CKD) patients.
- Conditions
- Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 5
- Trial name
- NCT01509716
- Where
- Singapore
- Volunteers
- 400 people
- Sponsor
- National University of Singapore
Chronic Kidney Disease
Patient INformation About Options for Treatment - PINOT
This prospective observational study is designed to find out what treatment options new patients with chronic kidney disease learn about from their renal unit.
- Trial name
- PINOT (NCT01298115)
- Where
- Australia
- Volunteers
- 721 people
- Sponsor
- University of Sydney
Kidney Failure, Arteriovenous Shunt
Maximizing Native Arteriovenous Fistulae Rates.
The purpose of our study is to compare physical examination alone to color Doppler ultrasonography (CDUS) vascular mapping and physical examination in terms of outcomes of vascular access and long-term patency.
- Conditions
- Kidney Failure, Arteriovenous Shunt, Hemodialysis
- Trial name
- NCT02705417
- Testing
- preoperative color Doppler ultrasonographic vascular mapping, physical examination, medical history
- Volunteers
- 136 people
- Sponsor
- Medifil AE
Anemia, Kidney Disease, Chronic
An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Patients With Chronic Kidney Disease in Pre-Dialysis or Dialysis
This prospective observational study will assess the efficacy and safety of Mircera (methoxy polyethylene glycol-epoetin beta) in clinical practice in patients with chronic kidney disease, in pre-dialysis or on dialysis…
- Trial name
- NCT01309295
- Where
- Albania
- Volunteers
- 250 people
- Sponsor
- Hoffmann-La Roche
Pre-dialysis, End Stage Renal Disease
NESP Pediatric Study
Open-label, randomized study of NESP in pediatric subjects 18 years of age or younger. Subjects will receive study drug (NESP or rHuEPO) for 28 weeks after a 2 week screening and baseline period.
- Trial name
- NCT00527137
- Testing
- darbepoetin alfa, rHuEPO
- Volunteers
- 120 people
- Sponsor
- Amgen
CKD, Renal Insufficiency Chronic
The CPH-MBD Cohort Dietary Substudy - Comparison of Methods for Dietary Registrations
The aim of the study is to assess the association between the calcium and phosphorus balance and the stage of kidney disease measured by creatinine clearence in patients with chronic kidney disease stage 4 and 5.
- Conditions
- CKD, Renal Insufficiency Chronic, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder, Pre-dialysis
- Trial name
- NCT07312981
- Where
- 2 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- University of Copenhagen
Anemia, Renal Insufficiency, Chronic
15141 Fixed Dose Correction / naïve and Pre Dialysis (Europe and Asia Pacific)
Anaemia is a condition in which blood has a lower than normal number of red blood cells. It can also occur if red blood cells do not contain enough haemoglobin, an oxygen carrying part of blood.
- Trial name
- DIALOGUE 1 (NCT02021370)
- Testing
- BAY85-3934
- Where
- 56 sites in Australia, Bulgaria and 12 more
- Volunteers
- 121 people
- Sponsor
- Bayer