Clinical trials: Pre-menopause
Depression, Healthy
Bone Loss in Premenopausal Women With Depression
The purpose of this study is to determine whether women with major depression lose bone mass at a faster rate than women without depression.
- Conditions
- Depression, Healthy, Osteopenia, Osteoporosis
- Trial name
- NCT00006180
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Sleep Disturbance
Kneipp Water Applications for Insomnia
The purpose of this study is to ascertain whether warm footbathes are effective on sleep disturbances in women before climacteric.
- Trial name
- KWAI (NCT03114189)
- Testing
- footbath, care of sleep
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universität Duisburg-Essen
Physical Inactivity, Obesity
Preliminary Efficacy of a Strength Training Intervention on Exercise Adherence and Weight Among Pre-Menopausal Women
The purpose of this study is to examine the feasibility and acceptability of a strength training-based intervention on exercise adherence among low active (defined as engaging in physical activity 90 minutes or less per week)…
- Trial name
- NCT05426070
- Testing
- Strength training-based exercise
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Vasomotor Symptoms (VMS) Associated With Menopause
An Observational Study to Learn More About Vasomotor Symptoms Burden and Treatment Patterns in Menopausal Women Before and After Participating in OASIS Studies
This is an observational study to learn more about vasomotor symptoms (VSM) burden and treatment patterns in menopausal women before and after participating in OASIS studies.
- Trial name
- OASIS STAR (NCT06949553)
- Testing
- No study intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Dry Eye Syndromes
Difference of Tear Ferning Between Women with and Without Menopausal.
Application of tear ferning test for clinical dry eye diagnosis and menopause
- Trial name
- NCT06848829
- Testing
- Pre-manepausal women
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Bariatric Surgery, Osteoporosis
Skeletal Health in Bariatric Surgery Patients
The investigators propose a prospective cohort trial that will help to understand the impact of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in pre- and post-menopausal female bariatric patients.
- Conditions
- Bariatric Surgery, Osteoporosis, Fractures, Bone, Roux En-Y Gastric Bypass
- Trial name
- NCT03331536
- Testing
- Roux en Y Gastric Bypass Pre-menopausal, Roux en Y Gastric Bypass Post-menopausal, Sleeve Gastrectomy Pre-menopausal
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Menopause, Cardiovascular Health
Acute Physiological Effects of Greek Traditional Dancing
In Greece, people of different age groups, including young children to older adults, are involved in traditional dance. To date, the well-know benefits of dancing include entertainment, socialization and increased physical…
- Conditions
- Menopause, Cardiovascular Health, Body Composition, Physical Performance
- Trial name
- NCT06260124
- Testing
- Slow tempo, Moderate tempo, Fast tempo
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Iron Deficiency Anaemia Due to Dietary Causes
Measuring Iron Bioavailability From Oral Iron Supplements in Healthy Pre-menopausal Women Using Stable Isotopes
In this study the investigators will compare iron absorption from 3 doses of iron (5, 10, 15 mg, given as either Spatone™ or ferrous sulphate).
- Trial name
- BOIs (NCT07563686)
- Testing
- 5mg Spatone, 10mg Spatone, 15mg Spatone
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- King's College London
Contraception
A Study to Compare 3 Doses of a Hormonal Intra-uterine Device Containing Levonorgestrel and Indomethacin With a Hormonal Intra-uterine Device Containing Only Levonorgestrel to Assess the Effect and Safety of the Combined Components
This study is the first study investigating the combined intrauterine administration of LNG (levonorgestrel) and IND (indomethacin). It is a combined proof-of-concept (PoC) and dose finding (DF) study in pre-menopausal women.
- Trial name
- INDessa (NCT03562624)
- Testing
- BAY98-7443, Levonogestrel (Skyla, BAY86-5028)
- Where
- 7 sites in Germany, United Kingdom
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Bayer
Overweight and Obesity
Betaine Supplementation and Lipid Metabolism in Overweight and Obese Pre-menopausal Women
Obesity represents a serious global health issue with significant consequences, including an increased risk of chronic diseases.
- Trial name
- NCT06344377
- Testing
- Betaine
- Where
- Poland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Infertility
Effects of Hormonal Infertility Treatment on Cognition in Pre-Menopausal Women
The purpose of this study is to examine the effects of marked alterations in ovarian steroid hormones on cognitive functions in women.
- Trial name
- NCT00113867
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Healthy Subjects
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ESN364 in Healthy Japanese Male and Pre- and Post-menopausal Female Subjects
The purpose of this study is to evaluate the safety and tolerability of single and multiple oral doses of ESN364 in healthy Japanese male and pre- and post-menopausal female subjects.
- Trial name
- NCT03436849
- Testing
- ESN364
- Where
- Japan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Obesity, Cardiovascular Disease
The WORLD (Weight Optimization: Revamping Lifestyles Using the Dietary Guidelines) Study - Developing, Implementing, and Testing an Education Program
The WORLD study is a single-center, year-long randomized controlled trial in free-living women. Participants were randomly assigned to follow either a lower-fat (LF) diet or a moderate-fat (MF) diet for weight management in a…
- Trial name
- WORLD (NCT00847574)
- Testing
- Moderate-fat, Lower-fat
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Penn State University
Breast Cancer
Acolbifene in Preventing Cancer in Premenopausal Women at High Risk of Breast Cancer
This phase II trial is studying how well acolbifene works in preventing cancer in premenopausal women at high risk of breast cancer. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT00853996
- Testing
- acolbifene hydrochloride
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Focus of the Study is Insulin Sensitivity
Effects of Dietary Fiber on Insulin Sensitivity
This study will examine the effects of a dietary fiber on insulin sensitivity in overweight and obese women. The fiber will be added to snack foods and women will consume the foods for four weeks.
- Trial name
- NCT01521806
- Testing
- Dietary Fiber
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ingredion Incorporated
Vitamin D Deficiency, Calcium
Resistive Exercise Versus HIIT on Calcium and Vitamin D
A comparison between resistive exercise and high intensity interval trainig on calcium and vitamin d in premenopausal women.
- Conditions
- Vitamin D Deficiency, Calcium, Premenopause
- Trial name
- NCT05795504
- Testing
- resistive exercise, high intensity interval training, calcium and vitamin D
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Density, Body Composition
Effects of an Exercise Program on Bone Density
Physical inactivity and low adherence to the Mediterranean diet cause alterations in body composition, which increases the risk factors for cardiovascular and metabolic diseases.
- Trial name
- NCT03308292
- Testing
- Exercise
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Coronary Artery Disease, Genetic Predisposition to Disease
Genetic Risk Stratification for Primary Prevention of CAD in Men and Pre & Post-menopausal Women
The investigators propose to genotype males and females at age 40 years and older, who are asymptomatic and without known heart disease (N=2000).
- Trial name
- NCT05169840
- Testing
- Genetic Risk Score for Coronary Artery Disease
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Metabolic Health, Mental Health
Health Benefits of Dance Exercise
In Greece, people of different age groups, including young children to older adults, participate in dance exercise training. Although it is well-known that regular participation in dancing is associated with benefits such as…
- Conditions
- Metabolic Health, Mental Health, Physical Performance
- Trial name
- NCT07615829
- Testing
- Exercise training, No exercise training
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Contraception
Dose-finding Study of MR-130A-01 Contraceptive Transdermal Patch
A single-center, randomized, open-label, parallel-group, multi-arm, phase II clinical trial in healthy women aged 18 to 35 years who have a documented ovulatory cycle prior to randomization.
- Trial name
- NCT06048536
- Testing
- MR-130A-01 Transdermal patch
- Where
- Germany
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc