Clinical trials: Pre-operative Bowel Prep
Bowel Cleansing Prior to Clinical Procedures, Colorectal Anastomosis
Oral Antibiotics vs. No Antibiotics in Pediatric Colorectal Surgery
This study aims to evaluate whether giving oral antibiotics before elective colorectal surgery can improve recovery and reduce complications in children.
- Trial name
- PEACO (NCT07713433)
- Testing
- oral antibiotics, No Oral Antibiotics
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Muhammad Zubair Shoukat
Colostomy, Hirschsprung Disease - Pull Through
Bowel Preparation in Elective Pediatric Colorectal Surgery
Infections after elective intestinal surgery remain a significant burden for patients and for the health care system. The cost of treating a single surgical site infection is estimated at approximately $27,000.
- Conditions
- Colostomy, Hirschsprung Disease - Pull Through, Necrotizing Enterocolitis, Inflammatory Bowel Diseases
- Trial name
- NCT03593252
- Testing
- Senna, Sodium Picosulfate, Magnesium Oxide and Citric Acid, Metronidazole Oral
- Volunteers
- 81 people
- Sponsor
- McMaster University
Colonoscopy, Bowel Preparation Quality
Effect of ChatGPT-Assisted Pre-Procedural Education on Bowel Preparation Quality and Anxiety in First-Time Colonoscopy Patients
Background and rationale: Colonoscopy is central to colorectal cancer screening and prevention, but its diagnostic yield depends heavily on adequate bowel preparation; inadequate cleansing lowers adenoma detection and often…
- Conditions
- Colonoscopy, Bowel Preparation Quality, Preoperative Anxiety, Patient Education
- Trial name
- NCT07732946
- Testing
- ChatGPT-assisted pre-procedural patient education, Standard pre-procedural information
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Gazi University
Pain, Postoperative, Analgesia
The Necessity of Preoperative Bowel Preparation
Hemorrhoidectomy is an common treatment for high-grade hemorrhoids. The necessity of preoperative bowel preparation (PBP) in hemorrhoidectomy is inconclusive.
- Trial name
- NCT05053542
- Testing
- Enema
- Where
- Taiwan
- Volunteers
- 273 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Pelvic Organ Prolapse, Prolapse
Pre-operative Bowel Preparation Prior to Minimally Invasive Sacral Colpopexy
Prior to surgery, gynecologists and urogynecologists have routinely prescribed preoperative mechanical bowel preparations in attempts to decrease the risk of infection, while also providing easier bowel manipulation and better…
- Trial name
- NCT01805310
- Testing
- Bowel preparation, No bowel preparation
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Halina M Zyczynski, MD
Surgical Wound Infection
Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis
Routine antibiotics for the intravenous and oral prophylaxis of colorectal surgery will be used. Experimental group: Patients undergoing elective colorectal surgery that involves, colonic resection.
- Trial name
- ORALEV (NCT02505581)
- Testing
- Extra dosage - cefuroxime (750mg) I.V, Colorectal Surgery, Ciprofloxacin 750 mg oral
- Where
- 3 sites in Spain
- Volunteers
- 536 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Bowel Preparation for Colonoscopy
Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose
The objective of this study is to compare the efficacy, safety and tolerability of two bowel preparations for colonoscopy - split dose Polyethylene Glycol-Based Lavage and Pico-Salax plus Bisacodyl - with a specific emphasis on…
- Trial name
- BP (NCT01415687)
- Testing
- Polyethylene Glycol-Based Lavage, Pico-Salax (Magnesium Citrate) plus Bisacodyl
- Where
- 2 sites in Canada
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colorectal Surgery, Pediatric
EFFECTIVENESS of PRE-OPERATIVE BOWEL PREPARATION VS NO BOWEL PREPARATION on OUTCOMES of PEDIATRIC COLORECTAL SURGERIES
To compare the effectiveness of pre-operative bowel preparation vs no bowel preparation on outcomes of pediatric colorectal surgeries.
- Conditions
- Colorectal Surgery, Pediatric, Bowel Preparation
- Trial name
- NCT06745505
- Testing
- Bowel Preparation
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Colonoscopy
Prospective Trial Of Osmolar Protocol Solution on Colonoscopy Outcomes and Patient Experience
Fasting is the current standard of care for colonoscopies. Recent changes to anesthesia guidelines have allowed for clear fluids to be provided up to 2 hours before procedures, including colonoscopies.
- Trial name
- POOPSCOPE (NCT05368792)
- Testing
- Complex Carbohydrate (PREcovery)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Health Centre Toronto
Anal Fistula, Fistula in Ano
Impact of Preoperative Bowel Preparation on Healing Outcomes in FiLaC
Background: Fistula tract laser closure (FiLaC) has emerged as a sphincter-preserving treatment for anal fistula (AF). However, the optimal role of preoperative bowel preparation (BP) in enhancing postoperative outcomes remains…
- Conditions
- Anal Fistula, Fistula in Ano, Laser, Anal Fistula Surgery
- Trial name
- FiLaC-PREP (NCT07800065)
- Testing
- Bowel preparation before fistula laser closure (FiLaC) surgery
- Volunteers
- 100 people
- Sponsor
- Acibadem Kent Hospital
Pre-operative Bowel Prep
Pre-op Bowel Prep Before Abdominal Surgery
Current management of elective bowel surgery typically involves performing a preoperative bowel preparation ("bowel prep") in many instances; however, this practice is not standardized at most institutions.
- Trial name
- NCT01512394
- Testing
- standard bowel prep, no bowel prep
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Elective Colon Surgery
Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery
The REaCT NSQIP will compare oral antibiotics vs. no antibiotics, which are two standards of care treatments for preoperative preparation of the bowel prior to colorectal surgery
- Trial name
- REaCT-NSQIP (NCT03663504)
- Testing
- No Preparation, Neomycin and Flagyl
- Where
- 6 sites in Canada
- Volunteers
- 630 people
- Sponsor
- Ottawa Hospital Research Institute
Value of the Bowel Preparation and Diet Change Versus no Intervention, Preoperative Bowel Regimen
Patient Experience and Bowel Preparation for Transvaginal Surgical Management of Vaginal Prolapse
Preoperative bowel preparation for surgical management of pelvic floor disorders is performed inconsistently, and includes no prep, the use of dietary changes or bowel altering interventions.
- Trial name
- NCT01431040
- Testing
- No bowel prep, Clear liquid diet and 2 Fleet's enemas
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Wounds and Injuries, Surgery--Complications
Preoperative Oral Antibiotics With vs Without Mechanical Bowel Preparation to Reduce Surgical Site Infections Following Colonic Resection: an International Randomized Controlled Trial.
The ORALEV Study found that preoperative oral antibiotics can reduce the incidence of surgical site infections after colonic resection, compared with no preparation.
- Trial name
- ORALEV2 (NCT04161599)
- Testing
- Cefuroxime (750mg) I.V, Colonic Surgery, Cefuroxime 750mg oral
- Where
- 10 sites in China, Greece and 4 more
- Volunteers
- 968 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Colonoscopy
Effect of Preoperative Automatic Reminder System on Colonoscopy
In this study, the investigators proposed an artificial intelligence-based preoperative automatic reminder system on colonocopy, which can improve the quality of bowel preparation and the rate of polyps and adenomas detection.
- Trial name
- NCT04996888
- Testing
- AI based preoperative automatic reminder system
- Where
- China
- Volunteers
- 829 people
- Sponsor
- Renmin Hospital of Wuhan University
Surgical Site Infection, Colorectal Cancer
Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs: A Propensity Analysis
Surgical site infections (SSIs) are a major postoperative complication after colorectal surgery. Current study aims to evaluate prophylactic function of oral antibiotic intake (OA) in combination with mechanical bowel preparation…
- Trial name
- NCT04258098
- Testing
- Oral antibiotics ( Streptomycin ,metronidazole )
- Volunteers
- 806 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Surgical Site Infection, Postoperative Complications
Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs
Surgical site infection (SSI) is a major postoperative complication after abdominal surgery especially in colorectal field, which significantly increases length of stay (LOS), readmission incidence and expense.
- Conditions
- Surgical Site Infection, Postoperative Complications, Bowel Preparation, Oral Antibiotics
- Trial name
- NCT03856671
- Testing
- Neomycin,metronidazole
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
POCD - Postoperative Cognitive Dysfunction, Mechanical Bowel Preparation
Investigation of the Effect of Preoperative Bowel Cleansing on Postoperative Cognitive Impairment
Cognitive impairment has been reported up to 54 % after colorectal surgeries. Mechanical bowel cleansing means that a system called the second brain in the body, which includes a wide variety of genetic and neuronal structures…
- Trial name
- NCT05942404
- Testing
- mechanical bowel preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- TC Erciyes University
Constipation, Ileus
Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery
This study investigated the effect of preoperative bowel preparations for patients undergoing spinal fusion surgery.
- Conditions
- Constipation, Ileus, Surgery
- Trial name
- NCT01879605
- Testing
- Docusate natrium and sorbitol, Bisacodyl
- Where
- Norway
- Volunteers
- 45 people
- Sponsor
- Oslo University Hospital