Clinical trials: Pre-term Delivery
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Preterm Birth, Preterm Labor
To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis
Implementation of prediction models of risk of spontaneous delivery within 7 days or of intra-amniotic infection in women with preterm labor and intact membranes
- Conditions
- Preterm Birth, Preterm Labor, Intra-amniotic Infection, Amniocentesis Affecting Fetus or Newborn
- Trial name
- OPTIM-PTL (NCT04831086)
- Testing
- Steroid Drug, Tocolytic Agents
- Where
- Spain
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Small for Gestational Age at Delivery, Low Birth Weight
Effect of a Fortified Balanced Energy-Protein Supplement on Birth Outcome and Child Growth in Houndé District, Burkina Faso.
The 2016 WHO antenatal care guidelines stated that pregnant women in undernourished populations should receive fortified balanced energy-protein (BEP) supplements to reduce the risk of stillbirth and small-for-gestational-age…
- Conditions
- Small for Gestational Age at Delivery, Low Birth Weight, Prematurity, Infant Malnutrition
- Trial name
- MISAME-3 (NCT03533712)
- Testing
- Fortified balanced energy-protein (BEP) supplement, Fe and folic acid supplement
- Where
- Burkina Faso
- Volunteers
- 1,788 people, healthy volunteers welcome
- Sponsor
- University Ghent
Parturition; Precipitate
Capturing Early Events in Human Parturition
This is a prospective observational study on normal singleton pregnant women who have no sign of labor at 40 weeks of gestation or pregnant women who admitted to hospital for any sign of labor at term, aiming to identify…
- Trial name
- NCT04411745
- Testing
- No intervention, observational study
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Preterm Birth, Preterm Delivery
Fitbit Activity Tracker to Predict Risk of Preterm Birth
Almost half of all deliveries in the United States are of nulliparous patients. They have been identified as an at-risk population for preterm birth.
- Trial name
- NCT03304782
- Testing
- Fitbit activity tracker
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Columbia University
Preterm Birth, Preterm Premature Rupture of Membrane
Cerclage After Full Dilatation Caesarean Section
CRAFT-OBS: Observational Study; To evaluate subsequent pregnancy risk of preterm birth in women with a history of previous caesarean in established labour.
- Conditions
- Preterm Birth, Preterm Premature Rupture of Membrane, Preterm Spontaneous Labor With Preterm Delivery
- Trial name
- CRAFT (NCT04110704)
- Testing
- Insertion of transvaginal cerclage
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Vaginosis, Bacterial, Abortion, Spontaneous
Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery
To determine whether screening of pregnant women with history of previous preterm delivery or with premature contractions for bacterial vaginosis using VS-SENSE, and treatment of positive women will reduce the risk of spontaneous…
- Conditions
- Vaginosis, Bacterial, Abortion, Spontaneous, Premature Birth
- Trial name
- NCT00491270
- Testing
- VS Sense
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Sleep Problem, Neurobehavioral Manifestations
NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood
The gut-brain axis plays a crucial role in the regulation and development of psychological and physical processes. The first year of life is a critical period for the development of the gut microbiome, which parallels important…
- Trial name
- NapBiome (NCT06396689)
- Testing
- Synbiotic
- Where
- 2 sites in Switzerland
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Petra Zimmermann
Healthy
Sonographic Prediction of Preterm Delivery Between 24-34 Weeks of Gestation
to evaluate if sonographic measure of short uterin cervix, sludge in amniotic fluid and abnormal doppler of the uterin artery can predict preterm labor
- Trial name
- NCT00613210
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Prematurity, Histologic Chorioamnionitis
Infant Immune Response to Bacterial Infection
This study will examine the response of white blood cells to bacterial infection in blood taken from the umbilical cords of newly delivered infants.
- Trial name
- NCT00546195
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diastolic Dysfunction, Neonatal Encephalopathy
Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
The goal of this single-centre longitudinal observational study is to create reference values for diastolic function parameters in neonates born at 35 weeks' gestation or above, and to assess the influence of pre-defined…
- Conditions
- Diastolic Dysfunction, Neonatal Encephalopathy, Small for Gestational Age at Delivery, Transient Tachypnea of the Newborn
- Trial name
- DiFuSE (NCT06200519)
- Where
- Ireland
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University College Cork
Preterm Birth, Short Cervical Length
The Impact of Vaginal and IM Progestins on the Cervix
The purpose of this study is to analyze how the body handles and responds to progesterone treatment in parous and nulliparous women at risk of pre-term birth.
- Trial name
- NCT01954095
- Where
- 4 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Prematurity; Decision Support
Decision Aid - Extreme Prematurity
The purpose of this study is to assess in a pilot randomized controlled trial the following PICOT question: In parents facing extreme premature delivery, does the use of an existing validated visual decision aid as compared to…
- Trial name
- NCT01713894
- Testing
- Decision Aid, Standard
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Pregnancy
Vaginal Progesterone to Reduce the Risk of Another Preterm Birth
This research study is being conducted at over 12 pregnancy research centers in the US. The study will compare an investigational treatment with a placebo (a treatment without medication).
- Trial name
- NCT00086177
- Testing
- 8% progesterone vaginal gel
- Where
- 45 sites in United States
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Juniper Pharmaceuticals, Inc.
Breastfeeding, Breastfeeding, Exclusive
Breastfeed a Better Youngster: the BABY Study
This research will investigate different aspects of the 'signalling' between mother and infant during breastfeeding in a stressful situation following late preterm and early term delivery, when breastfeeding is often challenging.
- Conditions
- Breastfeeding, Breastfeeding, Exclusive, Infant Behavior, Psychological Stress
- Trial name
- BABY (NCT03674632)
- Testing
- Relaxation meditation tape
- Where
- 2 sites in China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University College, London
Amblyopia, Child
Early Vision Screening in High-risk Children
To evaluate the effect of early vision screening with automated photorefraction device in high risk children
- Trial name
- NCT02678468
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Twin Pregnancy, Antepartum Condition or Complication, Twin to Twin Transfusion as Antepartum Condition
Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China
Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China (ChiTwiMC) is supported by National Key Research and Development Program of China - Reproductive Health and Women's and Children's Health Protection…
- Conditions
- Twin Pregnancy, Antepartum Condition or Complication, Twin to Twin Transfusion as Antepartum Condition, Pre-Term, Pre-Eclampsia
- Trial name
- ChiTwiMC (NCT06414655)
- Where
- 11 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Preterm Delivery
Biomechanics Based Prediction of Preterm Delivery
Quantitative information on the biomechanical properties of the ecto-cervix in mid-pregnancy will be compared between women with term vs. preterm delivery.
- Trial name
- Softcervix (NCT02037334)
- Testing
- Pregnolia System
- Where
- 13 sites in Belgium, Switzerland
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- David Scheiner
Caregiver Feeling
Feeling of Caregivers After a Palliative Management of Extreme Premature Babies in Delivery Room.
Introduction : The birth of a child is usually a happy event that caregivers working in delivery rooms share with families. Unfortunately, newborns sometimes need palliative care as soon as birth occurs.
- Trial name
- NCT06458114
- Testing
- Assessment of caregiver feeling
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2
Cerclage for Twins With Short Cervix
A prospective randomized control trial that will compare cervical cerclage plus vaginal progesterone to vaginal progesterone along in twin pregnancies complicate by a short cervix (</= 15.0mm) between 16w0d to 25w6d.
- Conditions
- Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2, Cervical Incompetence, Cervical Shortening
- Trial name
- NCT03077633
- Testing
- Cervical Cerclage placement, Vaginal Progesterone
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix