Clinical trials: PreDiabetes, completed
Diabetes Mellitus, Type 2, Schizophrenia
Metformin in Co-morbid Diabetes or Prediabetes and Serious Mental Illness
Schizophrenia is associated with a lifespan shortened by 20 years, due to cardiovascular disease (CVD), with antipsychotic (AP) medications understood to contribute to this risk through associated metabolic side-effects.
- Trial name
- NCT02167620
- Testing
- Metformin
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Centre for Addiction and Mental Health
PreDiabetes, Obesity
Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents
The study aims to investigate possible effects of per os Crocus Kozanis administration in children and adolescents with obesity
- Conditions
- PreDiabetes, Obesity, Dyslipidemias
- Trial name
- NCT05572749
- Testing
- Crocus Kozanis, Metformin
- Where
- Greece
- Volunteers
- 75 people
- Sponsor
- Aristotle University Of Thessaloniki
Pre-diabetes
Pre-Diabetes Cardiovascular (CV) Care (Pre-Diabetes Wizard)
Nearly one in three adults has prediabetes, a condition that substantially increases the risk of heart attacks and stroke. The increased cardiovascular risk associated with prediabetes can be effectively managed by lifestyle…
- Trial name
- NCT02759055
- Testing
- Clinical Decision Support
- Where
- United States
- Volunteers
- 21,664 people
- Sponsor
- HealthPartners Institute
Prediabetes, Obesity
Healthy Living Partnership to Prevent Diabetes
The Healthy Living Partnership to Prevent Diabetes (HELP PD) is a 300-participant randomized trial designed to test the effectiveness of a lay-health counselor led community-based diabetes prevention program in reducing blood…
- Trial name
- HELP PD (NCT00631345)
- Testing
- Group-Based Lifestyle Intervention (Phases 1 and 2), Individual Education Program (All Phases), Self-Directed Maintenance (Phase 3)
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pre-Diabetes, Diabetes
A1c FIT TEST: An Epidemiological Study Correlating Hemoglobin A1c With Results of the Air Force Physical FITness TEST.
The purpose of this study is to evaluate the prevalence of pre-diabetes and diabetes among those Air Force personnel who have not passed the Air Force physical fitness test (AFPT) and to evaluate the usefulness of the AFPT as a…
- Conditions
- Pre-Diabetes, Diabetes, Cardiovascular Risks
- Trial name
- NCT01301339
- Where
- United States
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
PreDiabetes
PreDM Clinical Decision Support Intervention
Clinical practice guidelines recommend intensive lifestyle interventions and metformin to prevent or delay type 2 diabetes; yet these treatments are not routinely used among the 86 million U.S.
- Trial name
- PreDM_CDS (NCT04335331)
- Where
- United States
- Volunteers
- 7,424 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pre-Diabetes
Community-based Adolescent Diabetes Prevention Program
The number of youth with type 2 diabetes is predicted to quadruple by 2050, with a disproportionate increase among minority youth.
- Trial name
- NCT02458131
- Testing
- TEEN HEED
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
PreDiabetes
The Effect of Lifestyle Modification on the Risk of Prediabetes Among Patients Attending Outpatient Clinic.
Diabetes mellitus is a major global health challenge, with type 2 diabetes (T2DM) accounting for nearly 90% of all cases worldwide.
- Trial name
- NCT07462078
- Testing
- Lifestyle modification
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Overactive Bladder, Insulin Resistance
Genomics and Epigenomics for New Insights in fEmale OAB (GENIE) Study
Millions of women suffer from overactive bladder, and the changes in bladder function affect their quality of life. The study team believes that it needs to be better understand why women get overactive bladder in the first place…
- Trial name
- GENIE (NCT03057158)
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Duke University
Diabetes, Neuropathy
Improving Autonomic Function and Balance in Diabetic Neuropathy
Type 2 diabetes (DM2) affects nearly 20 million people in the United States while impaired glucose regulation (IGR), which includes impaired glucose tolerance (IGT), impaired fasting glucose (IFG), and early diabetes affects a…
- Conditions
- Diabetes, Neuropathy, Impaired Glucose Tolerance
- Trial name
- IMABIN (NCT01864460)
- Testing
- lifestyle modification
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- VA Office of Research and Development
Type 2 Diabetes Mellitus, Pre-diabetes
Acute Effects of Cold-induced Shivering on 24-hour the Glucose Profile in Metabolically Compromised Populations
Type 2 Diabetes Mellitus (T2DM) and its associated comorbidities pose a major health concern worldwide. Although lifestyle strategies, such as exercise and diet-induced weight loss are effective interventions to counteract the…
- Trial name
- SHIVER (NCT05576025)
- Testing
- Lifestyle intervention (cold exposure)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Overweight, Obesity
Effect of Dietary Habits on Metabolic Health
The goal of this application is to understand the connection between people's eating habits and the risk for developing diabetes, obesity, and cardiovascular disease.
- Conditions
- Overweight, Obesity, Prediabetes, Meals
- Trial name
- NCT02298790
- Testing
- Meal schedule
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Glycemic Response
Study of a Carbohydrate Drink in Adults
The objective of this study is to determine the postprandial glycemic response and rates of gastric emptying in healthy subjects and those with pre-diabetes and type 2 diabetes following oral ingestion of carbohydrate.
- Trial name
- NCT04313920
- Testing
- Nutritional Supplement
- Where
- 3 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
PreDiabetes, Aging
Safety and Efficacy of KH-1 for Stimulating Autophagy in Non-diabetic Adults With Elevated Blood Glucose Concentration
Aging significantly impacts overall health and is a risk factor for developing diabetes. An estimated 50% of U.S. adults aged ≥65 years were reported to have prediabetes (defined as having a fasting glucose concentration of…
- Trial name
- NCT06445569
- Testing
- KH-1
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kalin Health, LLC
Pre-diabetes
The Insulin Sensitivity Using Aerobic Interval Conditioning
The Insulin Sensitivity using Aerobic Interval Conditioning (ISAIC) trial will compare traditional aerobic training (AER) to interval training (INT) in sedentary, overweight/obese men at risk for pre-diabetes.
- Trial name
- ISAIC (NCT01286922)
- Testing
- Behavioral: exercise
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes Mellitus
A Diabetes Prevention Study Targeting High Risk Individuals With Education and Ongoing Support
The study aims to identify people at high diabetes risk within the local population and then implement and evaluate a pragmatic and low-cost diabetes prevention programme containing structured education on lifestyle, physical…
- Trial name
- PREVENTION (NCT00677937)
- Testing
- Modified DESMOND education and ongoing support
- Where
- United Kingdom
- Volunteers
- 748 people
- Sponsor
- University Hospitals, Leicester
Insulin Resistance, Impaired Glucose Tolerance
Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight and Prediabetes (DISTAL)
The purpose of this study is to investigate the effects of a fibre mixture added to a high-protein diet on metabolic, gut and brain health.
- Conditions
- Insulin Resistance, Impaired Glucose Tolerance, PreDiabetes, Overweight and Obesity
- Trial name
- DISTAL (NCT05354245)
- Testing
- Fibre supplement (potato-pectin), High-protein diet
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Prediabetes
Prevention of Type 2 Diabetes With Vitamin D
The work plan will have the following S\&T components. Component 1: Cross-sectional Study Cross-sectional study will be of 1.5 years where 400 women from rural will be screened randomly for the vitamin D deficiency and its…
- Trial name
- PREVENT-WIN (NCT02513875)
- Testing
- vitamin D
- Where
- India
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Screening, Pre Diabetic
Prediabetes in End Stage Renal Disease on Dialysis
Prediabetes is a highly prevalent condition, affecting about one-third of adults in the United States Patients with prediabetes have an increased risk for diabetes, with 2% to 10% progressing to diabetes each yea Although…
- Conditions
- Screening, Pre Diabetic, Chronic Renal Failure (CRF), Dialysis Patients
- Trial name
- NCT07337083
- Where
- 2 sites in Egypt
- Volunteers
- 262 people
- Sponsor
- Sohag University
Type 2 Diabetes
The Effect of Vinegar on Glucose and Lipid Metabolism in Subjects With Impaired Glucose Tolerance or Type 2 Diabetes
This open, randomized, cross-over, placebo-controlled study aims to investigate the effects of vinegar on glucose metabolism, endothelial function and circulating lipid levels in subjects with impaired glucose tolerance or type 2…
- Trial name
- NCT02309424
- Testing
- Vinegar
- Volunteers
- 20 people
- Sponsor
- Attikon Hospital