Clinical trials: Prebiotic
Behaviour
Oxford Study of Prebiotics in Children
Recently, there has been an emerging interest in how manipulating gut microbiota (which is composed by microorganisms living in our digestive system) can influence learning, memory and cognition.
- Trial name
- OxPiC (NCT02926508)
- Testing
- Bimuno (BGOS), Maltodextrin
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Infant Nutrition Sciences
Acceptability, Tolerance, Satiety and Prebiotic Effect of a New Infant Cereal
This study evaluates a new infant cereals on acceptability, tolerance, satiety and prebiotic effect in infants.
- Trial name
- ACER (NCT02781298)
- Testing
- New Infant Cereal, Multicereals Infant Cereal
- Where
- 4 sites in Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hero Institute for Infant Nutrition
Metabolomics
The Effect of Feeding Infant Formula Containing Prebiotics and/or Probiotics
The study is intended to evaluate the microorganisms found in infant stools when consuming study formulas containing prebiotics and/or probiotics compared to infants consuming mother's own breast milk.
- Trial name
- NCT02948114
- Testing
- Control: Cow milk-based infant formula, Experimental 1: Cow milk-based infant formula, Experimental 2: Cow milk-based infant formula
- Where
- China
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Prebiotics, Anxiety
Gut-brain Axis, Brain Function, and Behaviour.
The aim is to test if dietary supplementation with prebiotics reduces measures of anxiety in healthy human participants with high self-reported levels of anxiety.
- Conditions
- Prebiotics, Anxiety, Humans, Magnetic Resonance Imaging
- Trial name
- NCT03554694
- Testing
- Prebiotics
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Elderly, Bowel Symptoms
Effects of β-glucans on Gut Permeability and Microbiota in Elderly
The investigators aim was to compare healthy young adults, senior orienteers (model of healthy ageing) and elderly with gastrointestinal symptoms on intestinal permeability, microbiota compositions and well-being.
- Conditions
- Elderly, Bowel Symptoms, Prebiotics
- Trial name
- NCT05584254
- Testing
- yeast-beta glucan
- Where
- Sweden
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Lower Respiratory Tract Infection, Upper Respiratory Tract Infection
Antiviral Activity of Oral Probiotics
The aim of this study is to test saliva samples obtained from healthy human participants for anti-viral activity after they have consumed S. salivarius probiotic in a powder format.
- Trial name
- NCT05374070
- Testing
- Streptococcus salivarius K12 Powder 1 Billion colony forming units /g), Streptococcus salivarius K12 Powder (1 Billion colony forming units /g) with a prebiotic included, Streptococcus salivarius M18 Powder (1 Billion colony forming units /g)
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- John Hale
Quality of Life, Health, Subjective
Resistant Starch Blend Gastrointestinal Impact
This study aims to test the hypothesis that a unique blend of resistant starches and fiber will promote gastrointestinal health, as measured by an increase in short-chain fatty acids and improvement in quality of life measures in…
- Trial name
- NCT03983772
- Testing
- RS blend
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Intestinal Health
Safety, Tolerability, and Biosignature of Humanized Prebiotics in Healthy Adults
This study aims to establish the safety of a 15 g/day dose of pure prebiotics ß(1-4) galacto-oligosaccharides (GOS) and GOS enriched with N-Acetyl-D-lactosamine, a building block of gut glycoproteins and human milk…
- Trial name
- NCT06068894
- Testing
- "Humanized" galacto-oligosaccharides (hGOS), Galacto-oligosaccharides (GOS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hypertension, Hyperglycemia
Effect of Dietary Fiber on Metabolic Syndrome, Gastrointestinal Function, Mood and Sleep Quality in Obese People
Metabolic syndrome includes hypertension(high blood pressure), hyperglycemia(high blood suger), dyslipidemia(abnormal blood lipid level) and obesity.
- Conditions
- Hypertension, Hyperglycemia, Dyslipidemia, Obesity
- Trial name
- NCT06626867
- Testing
- Dietary Fiber Supplementation
- Where
- Taiwan
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Chien-Wen Hou
Gut Microbiota Dysbiosis and Nutrition
Inulin and the Gut Microbiota in Healthy Adults
In this study the effects of a fibre dietary supplement on the gut microbiome in healthy adults will be investigated. For this purpose, a 14-day dietary supplementation with inulin or placebo (maltodextrin) will be carried out in…
- Trial name
- INLITE (NCT05399316)
- Testing
- Inulin, Maltodextrin
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Experimental and Clinical Research Center
Gastrointestinal Problems
Assessment of Efficacy and Tolerance of a Follow-On Milk Containing a Mixture of Prebiotics Fed to Young Children in Salvador, Bahia, Brazil
This clinical study will evaluate the effect on incidence of diarrhea, respiratory illness, stool patterns and growth of two cow's milk-based beverages for children.
- Trial name
- NCT01177605
- Testing
- Nutritional vanilla flavored beverage - 1) Milk-based beverage containing prebiotics 2) Milk-based beverage containing no prebiotics
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Respiratory Tract Infections (RTI)
Impact of AHCC® Supplementation for Prevention of Respiratory Tract Infections Among Children Age 4-6 Years Old
This is a study to evaluate the effects of a prebiotic, AHCC, a standardized extract of cultured Lentinula edodes mycelia, on immunologic markers and the incidence of respiratory tract infections in children.
- Trial name
- NCT07479394
- Testing
- a prebiotic, that us a standardized extract of cultured Lentinula edodes mycelia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Healthy
Influence of Food Matrix on Prebiotic Efficacy in Inulin Type Fructans
The aim of the study is to investigate whether the food matrix has an influence on the prebiotic efficacy (bifidobacteria growth) of chicory-derived Orafti® inulin in healthy adult volunteers.
- Trial name
- NCT05581615
- Testing
- Inulin
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Gut -Microbiota, As a Preliminary Study, Healthy Population's Gut Microbiota is Studied to See if Cellobiose Supplementation is Altering the Microbial Community or Not
In Vivo Human Study on Commercial Cellobiose as a Potential Prebiotic Candidate
The goal of this project is to investigate whether cellobiose, a type of sugar, has a beneficial effect on gut health when consumed by humans.
- Trial name
- C-prebiotics (NCT07097389)
- Testing
- Cellobiose, Oligofructose P95
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Manxi Huang
Overweight, Obesity
Effect of Prebiotic Intake on Adiposity, Satiety and Gut Microbiota in Overweight and Obese Children
Currently, over one third of Canadian children and youth aged five to seventeen are overweight or obese. Childhood obesity leads to increased risks of co-morbidities such as type 2 diabetes, fatty liver disease, cardiovascular…
- Trial name
- NCT02125955
- Testing
- Prebiotic fiber
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Healthy
Coffee Consumption, the Gut Microbiome, and the Microbiota-Gut-Brain Axis
The aim of this study is to investigate the potential of coffee to act as a prebiotic to alter gut microbiota and improve mood, memory and cognitive performance.
- Trial name
- NCT05927038
- Testing
- Caffeinated coffee, Decaffeinated coffee
- Where
- Ireland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University College Cork
Eating Behavior, Stress
The Gut Microbiota in Stress, Mood and Eating Behaviours.
Diet has a considerable influence on microbiota composition and the intake of either prebiotics (microbiota-specific food or probiotics (live microbiota species) has been shown to induce positive effects in both anxiety and…
- Conditions
- Eating Behavior, Stress, Mood
- Trial name
- NCT03482258
- Testing
- Prebiotic, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Functional Constipation
Study for the Management of Chronic and Functional Constipation Through the Intake of Probiotics and Prebiotics
The goal of this clinical trial is to learn if supplementation with prebiotics and/or probiotics can lead to an improvement in symptoms of patients with functional constipation.
- Trial name
- NCT06381193
- Testing
- Probiotic, Prebiotic, Probiotic + Prebiotic
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centros de Investigación de Nutrición y Salud
Hypertension, Gastrointestinal Microbiome
Effect of Prebiotics on Blood Pressure Management
This survey is designed to investigate the effect of highland barley β-glucan supplementation on the regulatory of blood pressure, gut microbiota and cardiovascular risk fators in subjects with hypertention.
- Trial name
- NCT05364736
- Testing
- Highland barley β-glucan dietary supplement
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Immunosenescence, Inflammation
Effect of Milk Protein and Prebiotics in Combination With Vitamin D on Innate Immunity in Elderly People
Rationale: The immune system in the ageing population becomes compromised with age (termed "Immunosenescence"). Therefore, elderly people have a decreased ability to respond to infection and vaccination.
- Trial name
- NCT03026244
- Testing
- Milk protein, prebiotics, vitamin D
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research