Clinical trials: Preconditioning
Ischemic Stress, Transient Non-Lethal Ischemia
The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress
Many studies have shown that if the human body is stressed by a lack of blood flow for a short period of time, the body develops defenses to make the body more resistant to a future stress from lack of blood flow.
- Trial name
- NCT00250185
- Testing
- Sodium Nitrate, Acetylcholine
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Tourniquets
Ischemic Preconditioning and Thiol-disulfide Balance
Various strategies have been proposed to prevent or mitigate the effects of ischemia-reperfusion injury following the use of tourniquets in orthopedic surgery cases.
- Trial name
- NCT05082207
- Testing
- Remote Ischemic Preconditioning
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Healthy Subjects (HS)
Aftereffects of PES Preconditioned with RTMS on the Human Pharyngeal Motor Cortex
The goal of this interventional study is to optimize the excitatory brain effects of combined neuromodulatory therapies on swallowing areas of the brain.
- Trial name
- NCT06884488
- Testing
- repetitive transcranial magnetic stimulation (Magstim Super Rapid stimulator, The Magstim Company Ltd, Whitland, UK), pharyngeal electrical stimulation (Digitimer model DS7; Welwyn-Garden City, Herts, UK)
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Cerebrovascular Disease, Stroke
Remote Ischemic Limb Preconditioning In Healthy Volunteers
The investigators would like to determine if remote ischemic leg preconditioning in healthy volunteers improves cerebral vasomotor reactivity as measured by breath holding and transcranial doppler vasomotor reactivity.
- Trial name
- NCT02553655
- Testing
- 4x 5min Limb Preconditioning, 3x 10min Limb Preconditioning
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Miami
Peripheral Vascular Disease
RCT to Evaluate the Renal Protective Effects of Remote Ischaemic Preconditioning in Peripheral Angioplasty
This study aims to demonstrate if remote ischaemic preconditioning (RIPC) may confer renal protection in patients undergoing peripheral angioplasty.
- Trial name
- NCT02054871
- Testing
- RIPC
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mid Western Regional Hospital, Ireland