Clinical trials: Preconditioning
Rheumatic Valve Disease
Clinical Trial of Electro-Acupuncture Preconditioning in Patients Underwent Heart Valve Replacement Surgery
The purpose of this study is to investigate the protective effect of electro-acupuncture preconditioning in patients underwent cardiac surgery.
- Trial name
- NCT00732459
- Testing
- Electro-acupuncture preconditioning
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Ischemia Reperfusion Injury
The Effect of Remote Ischemic Preconditioning in Patients Undergoing Major Liver Surgery
The project has been designed to determine whether a brief period of leg ischemia will reduce the I/R injury sustained by the liver during liver surgery and liver transplantation.
- Trial name
- NCT00796588
- Testing
- remote preconditioning
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- Royal Free Hampstead NHS Trust
Obliterating Arteriopathy of the Lower Limbs
Protection of Arteritic Patients by Remote Preconditioning
Prospective, monocentric, randomised, double-blind study with 20 patients enrolled to be explored twice through a Cross-over strategy to determine whether remote preconditioning improves arteritic patients' ability to walk.
- Trial name
- PARADIS (NCT01971879)
- Testing
- Remote ischemic preconditioning, Control
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Esophageal Malignant Neoplasm Primary, Anastomotic Leak
Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak
The main purpose of this study is to look at how often anastomotic leaks happen in participants who are at high risk of these leaks and are eligible to receive gastric preconditioning by percutaneous angioembolization before an…
- Trial name
- NCT07449208
- Testing
- Esophagectomy
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Ischemia-Reperfusion Injury, Free Flap
Non-invasive Remote Ischemic PreConditioning (RIPC) in Free Flaps for Breast Reconstruction
This prospective randomized clinical study investigates the effects of Remote Ischemic Conditioning (RIC) on tissue perfusion and ischemia-reperfusion injury in patients undergoing free flap reconstruction in reconstructive…
- Conditions
- Ischemia-Reperfusion Injury, Free Flap, Conditioning Therapy
- Trial name
- RIPC (NCT07487220)
- Testing
- Remote ischemic preconditiong
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- Ruhr University of Bochum
Carotid Stenosis, Endarterectomy, Carotid
Remote Ischemic Preconditioning for Carotid Endarterectomy
This is a randomized controlled trial designed to test an intervention (Remote ischemic preconditioning) in patients undergoing carotid endarterectomy (CEA) for carotid artery stenosis (CAS).
- Trial name
- RIP-CEA (NCT02808754)
- Testing
- Remote Ischemic Preconditioning
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Pittsburgh
Ischemia
Inspired Helium for Ischemic Protection During Knee Replacement Surgery
The purpose of this study is to determine whether breathing in helium reduces indications of injury to the skeletal muscle seen in blood tests after knee replacement surgery.
- Trial name
- NCT02012361
- Testing
- Control Group, Single-Dose Heliox Group, Muscle Biopsy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Ischemic Preconditioning
A Trial Comparing the Ischemic Preconditioning Effects of Ticagrelor and Clopidogrel in Humans
Antiplatelet therapy remains a cornerstone in the treatment of acute and chronic coronary artery disease. Aspirin was the first such therapy to prove its benefits in acute myocardial infarction.
- Trial name
- ETCH (NCT01743937)
- Testing
- Coronary occlusion with balloon inflation
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- University of Texas Southwestern Medical Center
Lower Extremity Explosive Power Deficit, Sports Recovery
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period
This study aimed to evaluate the effects of ischemic preconditioning on lower limb explosive power and post-exercise recovery in basketball players during a 6-week post-season recovery training period.
- Conditions
- Lower Extremity Explosive Power Deficit, Sports Recovery, Basketball Performance, Muscle Fatigue
- Trial name
- NCT07604948
- Testing
- Ischemic Preconditioning
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Guangzhou Sport University
Hypertension
Long-term of Remote Ischemic Preconditioning and Mindfulness in Patients With Mild Hypertension
According to the latest survey data of China hypertension annual meeting, there are about 300 million patients with hypertension in China, with 10 million new cases of hypertension each year, and there is an obvious trend of…
- Trial name
- NCT04753840
- Testing
- CRIC, MFT
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Myocardial Injury, Cardiac Surgery
Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery
The study aimed to evaluate the combined effects of cyclosporine and remote ischemic preconditioning on MDA, calcium cytosol concentration, and mitochondrial edema in tetralogy Fallot patients undergoing corrective surgery.
- Trial name
- NCT05691764
- Testing
- Cyclosporin, remote ischemic preconditioning
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Congenital Heart Disease
Remote Preconditioning and Myocardial Protection
Remote ischemic preconditioning (RIPC) of the myocardium by limb ischemia/reperfusion may mitigate cardiac damage, but its interaction with the anesthetic regimen is unknown.
- Trial name
- NCT02877238
- Testing
- Sevoflurane plus remote ischemic preconditioning, Total intravenous anesthesia plus remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Assiut University
Ischaemic Heart Diseases
The Effect of Ischaemic-Reperfusion and Ischaemic Preconditioning on the Endogenous Fibrinolysis in Man
Heart attacks are usually caused by a blood clot blocking an artery supplying blood to the heart. Current treatments are designed at relieving this blockage as quickly as possible to minimise damage to the heart muscle.
- Trial name
- NCT00789243
- Testing
- Forearm vascular study
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Liver Diseases
Ischemic Preconditioning at a Distance in Liver Surgery
During hepatic transection, it exists a high risk of perioperative blood loss. The haemorrhage and its consequences (hypovolemia and blood transfusion) might impact the short and long term morbidity The vascular control by…
- Trial name
- HEPATOPROTECT (NCT04181502)
- Testing
- pneumatic tourniquet, No inflation
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Hepatocellular Cancer
Effect of Remote Ischaemic preConditioning on Liver Injury in Patients Undergoing LIVER Resection Surgery
Liver resection has improved health outcomes in patients with hepatocellular carcinoma (HCC) in Singapore and worldwide. However, due to acute ischaemia/reperfusion injury (IRI) to the liver at the time of surgery, patients still…
- Trial name
- NCT03594929
- Testing
- Active RIC
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Chronic Kidney Disease
Reducing Hemodialysis Induced Recurrent Brain Injury to Improve Patients' Lives
Patients who receive dialysis for kidney failure suffer severe cognitive impairment. Hemodialysis causes circulatory stress and ischemia, which causes severe brain injury.
- Trial name
- NCT03342183
- Testing
- Intervention Arm, Control Arm
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stem Cell Transplant Complications, Relapse Leukemia
Decitabine Plus mBU/CY Preconditioning for Relapse/Refractory Acute Leukemia
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) remains one of the currently available curative therapies for acute leukemia (AL). Leukemia relapse is one of the mainly causes of transplant failure.
- Conditions
- Stem Cell Transplant Complications, Relapse Leukemia, Refractory Leukemia
- Trial name
- NCT03799224
- Testing
- Decitabine, mBU/CY and ATG, mBU/CY
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Peking University People's Hospital
Congenital Heart Disease, Cardiopulmonary Bypass
Seattle Cardiorenal Remote Ischemic Preconditioning Trial
Remote Ischemic Preconditioning (RIPC) is a treatment that may be associated with improved outcomes after cardiac surgery. It can be elicited noninvasively by using a tourniquet to elicit transient ischemia over a lower…
- Conditions
- Congenital Heart Disease, Cardiopulmonary Bypass, Myocardial Injury, Acute Kidney Injury
- Trial name
- SCRIPT (NCT01260259)
- Testing
- RIPC, Control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Seattle Children's Hospital
NK T-Cell Lymphoma
Preconditioning With a Combination of Thiotepa, Cyclophosphamide, and Busulfan for Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of NK/T-Cell Lymphoma
Evaluation of the efficacy and safety of Thiotepa combined with Cyclophosphamide and Busulfan as conditioning regimen before allo-HSCT for the treatment of NK/T cell lymphoma
- Trial name
- NCT07276737
- Testing
- Thiotepa
- Volunteers
- 37 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Stress Reaction, Stress Related Disorder
Research on the Effects of Combined Neurostimulation Protocols on Stress
The study examines the effects of the combined use of two different non-invasive brain stimulation (NIBS) techniques targeting the DLPFC on stress reactivity and recovery.
- Conditions
- Stress Reaction, Stress Related Disorder, Major Depressive Disorder
- Trial name
- NCT03722095
- Testing
- active tDCS, iTBS
- Where
- Belgium
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Ghent