Clinical trials: Prediabetes
Prediabetes, Gestational Diabetes
Treating Prediabetes in the First Trimester
The investigators plan to study a sample of women with prediabetes (diagnosed by Hemoglobin A1c (HbA1c) 5.7-6.4% or fasting plasma glucose (FPG) 92-125 mg/dL) in the first trimester of pregnancy, and patients will be randomized…
- Trial name
- NCT01926457
- Testing
- Treatment of Prediabetes
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity
Physical Activity Following Surgery Induced Weight Loss
The primary objective of this study will be to determine the effects of physical activity in patients during substantial surgery-induced weight loss.
- Trial name
- NCT00692367
- Testing
- Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pediatric Obesity, Insulin Resistance
Study of Post-meal Blood Sugar Peaks in Association With Vascular Disease in Childhood Obesity
The main purpose of this study is to determine whether treatment with acarbose attenuates post-prandial glycemic excursions in non-diabetic/pre-diabetic obese children as determined by continuous glucose monitoring systems…
- Conditions
- Pediatric Obesity, Insulin Resistance, Impaired Glucose Tolerance, Cardiovascular Disease
- Trial name
- NCT00846521
- Testing
- Acarbose
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Yale University
PreDiabetes, Insulin Sensitivity
Exercise Intervention for the Prevention of Prediabetes in Overweight Chinese
Overweight/obese Chinese and prediabetes will be recruited and divided into three age-matched groups including high intensity exercise, moderate intensity exercise, and non-exercise groups.
- Trial name
- NCT03240978
- Testing
- exercise intervention
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment, Prediabetes
Piedmont Aging, Cognition & Exercise Study-2
The purpose of this research study is to examine the effects of high and low intensity exercise for those with mild memory loss and pre-diabetes.
- Trial name
- PACE-2 (NCT02312843)
- Testing
- Exercise/Aerobic, Exercise/Stretching
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Diabetes Mellitus, Type 2, Obesity
The Glycemic Effect of Added Sugar on Bake Beans
To investigate the effect of added sugar to bake beans on glycemic and insulinemic response.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, PreDiabetes
- Trial name
- GIF (NCT03868683)
- Testing
- Glucose Reference 1, Glucose Reference 2, Glucose reference 3
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Eating Almonds Before a Meal to Control Blood Sugar
The goal of this study is to learn whether eating a small serving of almonds before meals can improve blood sugar control in adults who have early signs of problems with blood sugar regulation.
- Conditions
- Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Precision Medicine, Nutrition
- Trial name
- NUTS (NCT07603739)
- Testing
- Premeal almond ingestion
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diabetes, Prediabetes
The Usefulness of Postprandial Triglyceride for Assessment of Cardiovascular Risk
The hypertriglyceridemia at fasting status has been known to be an important risk factor for cardiovascular disease (CVD). Recently, postprandial triglyceride (TG) levels draw an attention as a superior predictor of CVD because…
- Trial name
- NCT01972542
- Testing
- Oral fat tolerance test
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Diabetes Mellitus, Type 2, PreDiabetes
Sardine-enriched Diet for Prevention Type 2 Diabetes
The hypothesis formulated is that 200 g of sardine on a weekly basis will have a favourable impact avoiding the natural development of the pathology due to changes in the biochemical profile, the anthropometrics, inflammatory…
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Diet Habit, Diabetes
- Trial name
- NCT03557541
- Testing
- Sardine, Control
- Where
- Spain
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Adiposity, Insulin Sensitivity
Metabolic Adaptations to High-fat Diet
The purpose of this study is to understand how the body's response after a meal is influenced by insulin and sugar in the blood.
- Conditions
- Adiposity, Insulin Sensitivity, Impaired Glucose Tolerance, Metabolic Disturbance
- Trial name
- MetFlexHFD (NCT06537401)
- Testing
- Hypercaloric, High Fat Diet
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- George Washington University
PreDiabetes, Overweight
Night Owl Metabolism
The proposed study uses a novel and rigorous randomized cross-over study design in youth (18-23y) with late and non-late chronotype (n=35 per group) to assess the glycemic effect of "aligning" an oral glucose tolerance test…
- Conditions
- PreDiabetes, Overweight, Impaired Glucose Tolerance
- Trial name
- NCT06507722
- Testing
- Timing of OGTT, Timing of Standardized Meal
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity, Glucose Intolerance
Prevalence of Carbohydrate Intolerance in Lean and Obese Children
The prevalence of obesity in children is reaching epidemic proportions. Excess adiposity is more than just a cosmetic problem, having substantial metabolic consequences.
- Conditions
- Obesity, Glucose Intolerance, Diabetes, Acanthosis Nigricans
- Trial name
- NCT00000112
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Community-Based Participatory Research
Evaluating Family & Community-Based Interventions to Improve Treatment Adherence in Metabolic Health Among Negev Bedouins (EFIT-BED)
Background: The Bedouin community in the Negev faces high rates of type 2 diabetes, low treatment adherence, and increased disease complications.
- Trial name
- EFIT-BED (NCT06575465)
- Testing
- Healthy lifestyle nutrition, culture and physical activity workshops, Usual care
- Where
- Israel
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ariel University
Pre Diabetes, Obesity
MapTrek to Increase Activity Among Patients at Risk for Type 2 Diabetes
The overarching objective of our work is to provide an inexpensive and scalable m-health tool to increase both volume and intensity of physical activity and reduce sedentary behavior in patients at risk for type 2 diabetes.
- Trial name
- NCT03193229
- Testing
- MapTrek, Fitbit
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Philip Polgreen
Respiratory Disorder, Cardiovascular Diseases
Study of RE.DOCTOR Vitals® Software Accuracy
The purpose of this observational trial is to advance digital health monitoring through the analysis of Photoplethysmography (PPG) waveforms collected via RE.DOCTOR Vitals software.
- Conditions
- Respiratory Disorder, Cardiovascular Diseases, Diabetes, Pre-Diabetes
- Trial name
- RE-VITAL (NCT06237322)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- RE.DOCTOR LLC
PreDiabetes
Prediabetes and Metabolic Parameters Among Young Adults at Assiut University Hospital
Prediabetes is a major public health problem that increases the risk of developing type 2 diabetes mellitus and cardiovascular complications.
- Trial name
- NCT07259954
- Testing
- No intervention
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 2 Diabetes, Overweight and Obesity
Acute Timed Exercise and 24h Metabolism
The primary objective of this randomized controlled cross-over study is to investigate if an acute, glycogen lowering exercise bout performed either in the morning or late afternoon differentially affects the respiratory exchange…
- Trial name
- TIM (NCT05073068)
- Testing
- Timing of exercise, Control
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Diabetes, Hypertension
Mobile Phone-based Intervention for Promoting Healthy Habits and Weight Loss
A self administered 16 weeks plus follow up study to explore the efficacy of mobile phone driven apps for stress reduction coupled with guidance for healthy living among obese and overweight populations.
- Conditions
- Diabetes, Hypertension, Pre-diabetes, Overweight
- Trial name
- NCT02621008
- Testing
- Stress Reduction& Healthy living
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Eco Fusion
Dyslipidemia, Diabetes
Meta-analyses of Fructose and Cardiometabolic Risk
Diabetes and heart associations continue to discourage high intakes of dietary fructose, a constituent part of the sucrose molecule that is found in fruits and vegetables as a natural sugar and in some processed foods and…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01363791
- Testing
- Dietary fructose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Prediabetic State
DPP-4 Inhibition and TZD for DM Prevention
To determine whether treatment with the diabetes medication, Januvia (sitagliptin), with or without another diabetes medicine, Actos (pioglitazone), will improve insulin secretion and insulin response individuals with Impaired…
- Trial name
- DInT DM (NCT01006018)
- Testing
- Sitagliptin + Pioglitazone
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Emory University