Clinical trials: Prediabetes / Type 2 Diabetes
Cardiovascular Diseases, Obesity
Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility
SWIFT-CORE-101 is a single site survey study designed to assess potential participants' eligibility to screen for industry-sponsored clinical trials.
- Conditions
- Cardiovascular Diseases, Obesity, PreDiabetes, Diabetes Type 2
- Trial name
- SWIFT-CORE-101 (NCT06412536)
- Testing
- Blood work
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brooklyn Clinical Research
Type II Diabetes Mellitus
Effects of a Spiced Meat Patty on Inflammation in Men With Type 2 Diabetes
Polyphenols belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile…
- Trial name
- NCT01076829
- Testing
- Spice polyphenols
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Impaired Fasting Glucose, Impaired Glucose Tolerance
Type 2 Diabetes Mellitus Prevention Ukraine
Development, implementation and evaluation of the effectiveness of lifestyle recommendations for the prevention of type 2 diabetes in rural population of Ukraine
- Conditions
- Impaired Fasting Glucose, Impaired Glucose Tolerance, Type 2 Diabetes
- Trial name
- T2DPUA (NCT04283201)
- Testing
- Physical activity, Macronutrient modification
- Where
- Ukraine
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Komisarenko Institute of Endocrinology and Metobolism
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.
- Conditions
- Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female, Adult, Endothelial Function (Reactive Hyperemia)
- Trial name
- NCT06735651
- Testing
- Wild Blueberry
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgia State University
Breast Cancer, PreDiabetes
Diabetes Care for Breast Cancer Patients
The goal of this study is to find a new way to make diabetes care better for patients with breast cancer and diabetes who are currently receiving cancer treatment.
- Conditions
- Breast Cancer, PreDiabetes, Type 2 Diabetes
- Trial name
- NCT05565534
- Testing
- Nurse-practitioner led intervention
- Where
- 3 sites in United States
- Volunteers
- 74 people
- Sponsor
- Weill Medical College of Cornell University
Insulin Resistance, Type 2 Diabetes Mellitus
Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes
The purpose of this study is to examine the effects of treating insulin resistance on memory and attention, brain glucose utilization, and proteins in spinal fluid.
- Trial name
- NCT00212290
- Testing
- pioglitazone, nateglinide
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 2, PreDiabetes
iCan Diabetes Self-management and Prevention Program
The purpose of this study is to test the feasibility and preliminary efficacy of the iCan Diabetes Self-Management and Prevention Support Group using a single arm clinical trial.
- Trial name
- NCT05571436
- Testing
- iCan Diabetes Self-management and Prevention Support Group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Diabetes Mellitus, Type 2, Obesity
Microbiome and Health Indicators in People With Obesity, Prediabetes and Type 2 Diabetes Undergoing a Lifestyle Intervention
The incidence of type 2 diabetes worldwide is growing rapidly, being one of the fastest growing global health emergencies of the 21st century according to the International Diabetes Federation.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, PreDiabetes
- Trial name
- MicrobiAr (NCT05372445)
- Testing
- Non-intensive intervention, Intensive intervention
- Where
- Argentina
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Nutritional and Metabolic Diseases, Prediabetes
LIfestyle MEtabotype Study A
Glycemic responses vary significantly among individuals, even when consuming identical foods or meals, but the factors predicting individual glucose response to food intake remain poorly investigated.
- Conditions
- Nutritional and Metabolic Diseases, Prediabetes, Type 2 Diabetes
- Trial name
- LIME-A (NCT07868601)
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Type 1 Diabetes (T1D), Pre Diabetes
INNODIA Family & Friends Early-Stage T1D Detection Protocol
The purpose of INNODIA DETECT is to identify people who are at increased risk of developing T1D. Investigators are doing this by testing for markers in the blood (autoantibodies) that tell them an individuals risk of getting T1D…
- Trial name
- INNODIA DETECT (NCT07118098)
- Where
- 21 sites in Austria, Belgium and 6 more
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- INNODIA iVZW
PreDiabetes, Circadian Dysregulation
Morning Light Treatment to Improve Glucose Metabolism
The primary purpose of this pilot study is to test a novel head worn light device (Re-Timer®) as an intervention to improve glucose metabolism in people with prediabetes.
- Trial name
- ML (NCT03188263)
- Testing
- Bright Light, Dim Light
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Stroke Recurrence, Type 2 Diabetes
Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes
Objectives: This study aims to test whether a mobile app called PortionSize Ed can help adults who have had a recent stroke and also have prediabetes or type 2 diabetes improve their diet.
- Conditions
- Stroke Recurrence, Type 2 Diabetes, Prediabetes
- Trial name
- NCT07120334
- Testing
- PortionSize Ed + MedDiet Support, Standard of care for Stroke and Prediabetes or T2D
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Hawaii
Type 2 Diabetes, Muscular Atrophy
Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes
The purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest in older adults with pre-diabetes and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise
- Trial name
- RECOVER (NCT04057677)
- Testing
- Bed Rest Intervention, Exercise Program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Overweight, Obesity
Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)
Type 2 diabetes and prediabetes, which are mainly caused by a lack of physical activity and excess weight, put people at an increased risk of cardiovascular disease.
- Conditions
- Overweight, Obesity, Type 2 Diabetes, Prediabetes
- Trial name
- SHAPE3 (NCT00928005)
- Testing
- Weight loss diet, Weight loss diet plus exercise
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Type 2 Diabetes, PreDiabetes
Effect of Selenium Supplementation on Glycemic Control in Patients With Type 2 Diabetes or Prediabetes
Although it has been suggested that selenium (Se) increases the risk of T2DM, most evidence comes from observational studies that cannot prove causality.
- Trial name
- NCT05320510
- Testing
- Se-yeast
- Volunteers
- 130 people
- Sponsor
- Huazhong University of Science and Technology
Diabetes Mellitus, Type 2, Prediabetic State
Finding the Patient's Voice Diabetes Prevention Programs
This study uses patient engagement to develop a diabetes prevention program focused on adolescents and families.
- Trial name
- NCT02700503
- Testing
- Encourage 2.0
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Indiana University
Prediabetic State
Pilot Stair Climbing Study
This pilot study seeks to demonstrate feasibility to conduct data collection and illustrate potential for effect of fractionalized bouts of stair climbing on glucose control in adults at risk for type 2 diabetes.
- Trial name
- NCT02827383
- Testing
- Stair Climbing Frequency
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jennifer Gay
Food Insecurities, Cardiometabolic Comorbidities
Human Immunodeficiency Virus (HIV) Food Insecurities
The objectives of this study are to better understand how FI (food insecurities) contributes to the development of cardiometabolic comorbidities among PWH (People with HIV) and to test a novel bilingual FI intervention designed…
- Conditions
- Food Insecurities, Cardiometabolic Comorbidities, HIV, PreDiabetes
- Trial name
- NCT04943861
- Testing
- weCare/Secure, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University Health Sciences
Type 2 Diabetes, PreDiabetes
Recreational Basketball to Increase Participation in Diabetes Prevention
The purpose of this study is to assess the efficacy of adapting the National Diabetes Prevention Program (NDPP) to include recreational sports in effort to increase physical activity (PA) and promote lifestyle changes that can…
- Trial name
- DPPHoops (NCT05066542)
- Testing
- NDPP + Basketball (BB), NDPP Standard of Care SOC
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obesity, Uric Acid Stones
Phentermine/Topiramate for Uric Acid Stones
The investigator proposes an 18 month, feasibility pilot study, randomizing obese and diabetic individuals with pure uric acid nephrolithiasis (UAN) or mixed calcium oxalate (CO) UAN to either phentermine/topiramate or a…
- Conditions
- Obesity, Uric Acid Stones, Type 2 Diabetes Mellitus in Obese, Pre-Diabetes
- Trial name
- NCT04621929
- Testing
- Phentermine / Topiramate Oral Product, Citrate Salts, Allopurinol, Diet
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Florida