Clinical trials: Predialysis
Anemia in Pre-Dialysis Patients
Clinical Study of R744 to Predialysis Patients
This study will assess the efficacy and safety of subcutaneous or intravenous R744 in renal anemia patients on Predialysis.
- Trial name
- NCT00433615
- Testing
- R744
- Where
- 6 sites in Japan
- Volunteers
- 124 people
- Sponsor
- Chugai Pharmaceutical
Renal Failure
Two Schedules of Hepatitis B Vaccination in Predialysis Chronic Renal Failure Patients
Patients with chronic renal disease have to be vaccinated as soon as dialysis is forestalled and this could improve seroconversion rate of hepatitis B vaccination.
- Trial name
- NCT01468051
- Testing
- four doses of Euvax B vaccine, 20 μg (1 ml) three doses of Euvax B vaccine
- Volunteers
- 51 people
- Sponsor
- Tehran University of Medical Sciences
Hypertension
VALID: Study to Compare the Reduction of Predialysis Systolic Blood Pressure With Valsartan Compared to Irbesartan in Patients With Mild to Moderate Hypertension on Long-term Hemodialysis
The purpose of the study is to compare the efficacy, safety and tolerability of valsartan 80 mg (with a starting dose of 40 mg) to irbesartan 150 mg (with a starting dose of 75 mg) in patients on long-term haemodialysis with mild…
- Trial name
- NCT00171080
- Testing
- valsartan, irbesartan
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 86 people
- Sponsor
- Novartis
Anemia
A Study of Once-Monthly Subcutaneous Mircera for the Treatment of Chronic Renal Anemia in Pre-Dialysis Patients Not Currently Treated With ESA.
This single arm study will assess the efficacy and safety of subcutaneous Mircera for the correction and maintenance of hemoglobin levels in predialysis patients with renal anemia who are not currently treated with ESA.
- Trial name
- NCT00680563
- Testing
- methoxy polyethylene glycol-epoetin beta [Mircera]
- Where
- 22 sites in Argentina, Brazil and 8 more
- Volunteers
- 4 people
- Sponsor
- Hoffmann-La Roche
Anemia
A Study of Monthly Subcutaneous Mircera for the Treatment of Chronic Renal Anemia in Predialysis Patients Not Treated With ESA.
This single arm study will assess the efficacy and safety of subcutaneous methoxy polyethylene glycol-epoetin beta (Mircera) for the correction and maintenance of hemoglobin levels in predialysis patients with renal anemia who…
- Trial name
- NCT00661388
- Testing
- methoxy polyethylene glycol-epoetin beta [Mircera]
- Where
- 9 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Hoffmann-La Roche
Chronic Kidney Disease
Chronic Kidney Disease at Northeast Taiwan: Biomarker and Multidisciplinary Care
CKD is a global endemic disease with increased comorbidities and mortality. The prevalence and the incidence of the end-stage renal disease (ESRD) are extremely high in Taiwan.
- Trial name
- NCT04300387
- Testing
- multidisciplinary care
- Where
- Taiwan
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Anemia
A Study of Monthly Subcutaneous Continuous Erythropoietin Receptor Activator (CERA) in Predialysis Participants With Chronic Renal Anemia
This single arm study will assess the long term maintenance of hemoglobin (Hb) levels, safety and tolerability of once monthly subcutaneous methoxy polyethylene glycol-epoetin beta (CERA) in predialysis participants with chronic…
- Trial name
- ORION (NCT00773968)
- Testing
- Methoxy Polyethylene Glycol-Epoetin Beta
- Where
- 34 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Hoffmann-La Roche
Chronic Kidney Disease, Anemia
Study of Roxadustat in Non-Dialysis Chronic Kidney Disease Participants With Anemia
The primary purpose of this study is to evaluate efficacy and safety of roxadustat in the correction of anemia in participants with non-dialysis chronic kidney disease.
- Trial name
- NCT01244763
- Testing
- Roxadustat
- Where
- 38 sites in United States, Puerto Rico
- Volunteers
- 145 people
- Sponsor
- Kyntra Bio
Chronic Kidney Disease
Effect of Exercise on Renal Function in Predialysis
The proposed research aims to examine whether regular aerobic exercise can preserve renal function, improve aerobic capacity, physical and psychosocial function, strength, cardiovascular function, general well-being and quality…
- Trial name
- NCT02155036
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College Hospital NHS Trust
Hepatitis B Virus Infection
Hepatitis B Vaccine Predialysis/Dialysis Study (V232-060)
To describe the immunogenicity and safety of modified process hepatitis B vaccine administered to renal predialysis and dialysis patients
- Trial name
- NCT00440297
- Testing
- Comparator: modified process hepatitis B vaccine, Comparator: ENGERIX-B™
- Volunteers
- 277 people
- Sponsor
- Merck Sharp & Dohme LLC
Chronic Kidney Disease
Low Protein Renal Formula as Meal Replacement in Predialysis CKD Patients
A high energy and low protein renal formula tailored for the specific needs of pre-dialysis CKD patients.
- Trial name
- NCT05330663
- Testing
- Low protein diet with Fresubin® renal, Low protein diet with normal food
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- Taichung Veterans General Hospital
Stage 2-5 Chronic Kidney Disease, Predialysis
Vitamin D Insufficiency and Deficiency in Chronic Kidney Disease (CKD) Patients in Singapore
Vitamin D insufficiency and deficiency is common in chronic kidney disease (CKD) patients and is associated with elevated parathyroid hormone (PTH) concentration and mineral and bone disorder (MBD).
- Trial name
- NCT01102179
- Where
- Singapore
- Volunteers
- 196 people
- Sponsor
- National University of Singapore
Predialysis Patients
Clinical Study of R744 to Predialysis Patients( Phase III, Comparative Study in Comparison With Epoetin Beta)
This study used as the comparative drug (epoetin beta) will assess the efficacy and safety of subcutaneous R744 in renal anemia patients on Predialysis.
- Trial name
- NCT00492427
- Testing
- R744, Epoetin beta
- Where
- 6 sites in Japan
- Volunteers
- 187 people
- Sponsor
- Chugai Pharmaceutical
Chronic Kidney Disease
Effect of a Phosphate Modified Diet on Phosphate Balance and Phosphate Metabolism in Predialysis Patients Stage 3-4
Patients with chronic kidney disease struggle to eliminate phosphate as the renal function deteriorates, which results in accumulation of phosphate in the body.
- Trial name
- NCT02073136
- Testing
- Diet with phosphate containing additives, Diet without phosphate containing additives
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- University of Copenhagen
Anemia, Chronic Renal Insufficiency
Randomized, Controlled, Double-blind Multicenter Safety Study to Evaluate the Safety and Immunogenicity of Subcutaneous EPO HEXAL vs. ERYPO® in the Treatment of Anemia Associated With Chronic Renal Insufficiency in Predialysis Patients
This is a randomized, controlled, double-blind, multicenter multinational safety study involving about 300 predialysis patients aged 18 years or above suffering from anemia. Symptomatic anemia will be corrected by s.c.
- Trial name
- NCT00701714
- Testing
- HX575 recombinant human erythropoietin alfa, ERYPO
- Where
- 123 sites in Austria, Bulgaria and 8 more
- Volunteers
- 337 people
- Sponsor
- Sandoz
Vascular Calcification
Oral Alfacalcidol and Coronary Artery Calcification in Predialysis Chronic Kidney Disease
Active vitamin D at therapeutic dose may prevent vascular calcification but in supraphysiologic dose may precipitate it.
- Trial name
- NCT01364688
- Testing
- oral alfacalcidol, no drug
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Ramathibodi Hospital
Telenurse, CKD Stage 3/4
EFFECTS OF TELENURSING IN PREDIALYSIS PATIENTS
This study aims to evaluate the effect of tele-nursing practices on quality of life and clinical outcomes in predialysis patients with chronic kidney disease.
- Trial name
- Telenurse-CKD (NCT07669142)
- Testing
- Structured Telenursing Education, Counseling, and Follow-up Program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Kidney Disease, Predialysis
Educational Program on Dietary Adherence and Nutritional Knowledge in Chronic Kidney Disease Patients (EPAK)
A fundamental strategy to improve adherence to nutritional treatment in patients with chronic kidney disease is the implementation of educational programs.
- Conditions
- Chronic Kidney Disease, Predialysis, Peritoneal Dialysis, Hemodialysis
- Trial name
- EPAK (NCT06351007)
- Testing
- Nutritional education and psychological intervention, Standard care
- Where
- Mexico
- Volunteers
- 63 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Chronic Kidney Disease
Intensive Dietary Education to Lower Serum Phosphorus in Patients With Chronic Kidney Disease
A low phosphorus diet is recommended for patients with chronic kidney disease who exhibit high levels of phosphorus. The purpose of this study is to determine the effects of a more intensive, innovative dietary phosphorus…
- Trial name
- NCT00656279
- Testing
- Intensive dietary phosphorus education
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Unity Health Toronto
Chronic Kidney Disease Predialysis
Effects of Combination Exercise on Fatigability in Veterans With Chronic Kidney Disease
The VA health care system uses a health promotion-focused model which aims to provide longitudinal care through a patient-aligned care team for Veterans with chronic kidney disease.
- Trial name
- NCT04397159
- Testing
- Combination Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development