Clinical trials: Prediction
Intrahepatic Cholestasis of Pregnancy
Unraveling the Pathogenesis of Pruritus in Intrahepatic Cholestasis of Pregnancy
This study hopes identify the main pruritogens of ICP pruritus and provide new insights for the diagnosis, prediction, and treatment of ICP.
- Trial name
- NCT06366659
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking University
COVID-19, Long COVID
CORona (COVID-19) Follow Up Study: Epidemiology, Pathophysiology, Prediction, and Communication
The CORFU study, funded by ZonMW, is a prospective, multiple, cohort study with a maximum follow-up of 24 months after COVID-19.
- Conditions
- COVID-19, Long COVID, Post COVID-19 Condition
- Trial name
- CORFU (NCT05240742)
- Testing
- no intervention, the CORFU study conducts analyses based on data which has been prospectively collected (and aggregated when possible) in 7 existing cohorts
- Where
- Netherlands
- Volunteers
- 4,291 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pre-Eclampsia, Severe, HELLP Syndrome
Promising Bimarker Prediction of Outcome of HELLP Syndrome.
HELLP syndrome is a life-threatening obstetric complication usually considered to be a variant or complication of pre-eclampsia.
- Conditions
- Pre-Eclampsia, Severe, HELLP Syndrome, Microangiopathy
- Trial name
- NCT03246542
- Testing
- shistocytes percentage
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AYMAN ABDELKADER MOHAMED ABDELKADER
Fetal Growth Restriction (FGR), Preterm Birth
Enhancing Prediction of Adverse Pregnancy Outcomes in Africa Through Partnerships and Innovation
Pregnancy complications such as pre-eclampsia (high blood pressure during pregnancy), poor fetal growth, unexplained stillbirth, and spontaneous preterm birth are major causes of illness and death for mothers and babies in…
- Conditions
- Fetal Growth Restriction (FGR), Preterm Birth, Still Births, Abruptio Placentae
- Trial name
- EPAPOA (NCT07844876)
- Where
- 2 sites in Uganda
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Makerere University
Seizures, Epilepsy
Ear-Seizure Detection (EarSD) Study
The proposed study is an investigator-initiated study that aims to measure the accuracy of a wearable seizure detection and prediction device (Ear-Seizure Detection Device (EarSD)) by simultaneous recording with conventional…
- Trial name
- EarSD001 (NCT06598189)
- Testing
- Ear-SD, Electroencephalogram
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Felicia Chu
Adrenal Insufficiency, Inflammatory Lung Diseases
The Significance of Defensin Alpha 4 in the Pathophysiology of the Adrenal Insufficiency in Inflammatory Lung Diseases
The pathophysiology of the adrenal insufficiency of patients with critical diseases remains unclear. In a prior exploratory study investigating patients with exacerbation of chronic obstructive pulmonary disease (COPD), the…
- Trial name
- NCT01703013
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Preeclampsia/Toxemia
The Prediction of Preeclampsia/Toxemia in Twin Pregnancy
The purpose of this study is to finout whetere uterinae artery flow , PP13 and endogolin levels in the serum and kongo red in the urine can predict preeclamsia toxemia in twin pregnancies.
- Trial name
- NCT01255202
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Patient Safety
Machine Learning Prediction of Parameters of Early Warning Scores in Intensive Care Units
A large number of different organ functions are recorded in real time for patients being monitored in an intensive care unit. On the one hand, the measured values collected are used for continuous monitoring of vital parameters…
- Trial name
- AIM-PEW-ICU (NCT06259812)
- Testing
- Parameters of Early Warning Scores
- Where
- Austria
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Kepler University Hospital
Spinal Cord Injuries (SCI), Blood Pressure
AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury
The goal of this clinical trial is to determine if perfusion index (PI) can reliably predict changes in systolic blood pressure (SBP) in persons with spinal cord injury (SCI) during a cool temperature challenge.
- Conditions
- Spinal Cord Injuries (SCI), Blood Pressure, Thermoregulation, Perfusion Index
- Trial name
- NCT07699094
- Testing
- Controlled Cool Thermal Challenge (18°C)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Healthy Aging, Lifestyle Risk Reduction
Biological Age Applied at Ubberup
In a previous study the investigators have developed a novel biological age model. Assessing biological age is the assessment of the present health status and functional capacity/physiological reserve of that person in comparison…
- Trial name
- NCT04279366
- Testing
- Lifestyle intervention
- Where
- 2 sites in Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Uterine Cervical Neoplasms
Clinical Study on the Evaluation of the Efficacy of Cervical Cancer
The main objectives of this study are to construct a multi-omics-based prognostic and side-effect prediction model for cervical cancer based on pre-treatment imaging, digital pathology, genomics, proteomics, molecular biology…
- Trial name
- EECC (NCT06254729)
- Testing
- Observational study
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Infectious Disease
Antibiotic Outbreak, Risk Factors for Never Event, Prediction of Inappropriate Use
In order to decrease inappropriate antibiotic use, drivers of inappropriate use must be identified locally. This study will focus on the MOST inappropriate use, which are defined as 'never events'.
- Trial name
- NCT03489330
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Dyspnea, Breathlessness
Breathlessness During Exercise: Experience and Memory
Breathlessness during exertion is a major limiting factor for patients' physical capacity and activity. Increased exertional breathlessness often results in impaired activity, spiraling deconditioning and further worsening of…
- Trial name
- NCT03458182
- Testing
- Added exercise
- Where
- Sweden
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Magnus Ekström
Mycosis Fungoides, Sezary Syndrome
Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome.
A translational study for identification of prognostic and treatment-predictive biomarkers in Mycosis fungoides and Sézary syndrome.
- Trial name
- BIO-MUSE (NCT04904146)
- Testing
- Blood tests and testing of analysis of the lymphoma microenvironment in skin, skin barrier and skin microbiology profile.
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Lund University Hospital
Alzheimer Disease, Battery
Prediction of Cognitive Properties of New Drug Candidates for Neurodegenerative Diseases in Early Clinical Development
The early assessment of new drugs for Alzheimer's disease remains difficult because of the lack of predictive end-point. The use of a battery including different parameters could improve this early development of new drugs.
- Trial name
- PharmacogWP3 (NCT01487395)
- Testing
- Donepezil .
- Where
- 3 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Colorectal Polyp
Prediction of Diminutive/Small Polyp Histology: Didactic vs. Computer-based Training
Bowel cancer is one of the most common cancers and the best method of diagnosing it is through endoscopic examination of the bowel (colonoscopy).
- Trial name
- NCT03843567
- Testing
- Endoscopic characterisation training
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Rectal Cancer, Low Anterior Resection Syndrome
Feasibility and Impact of a Prehabilitation and Rehabilitation Program for the Continuity of Care in Severe Low Anterior Resection Syndrome.
Patients with sphincter saving procedures of rectal cancer usually experience intestinal dysfunction, including difficulty emptying the bowel and faecal incontinence, leading to a detriment in the quality of life.
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, Faecal Incontinence
- Trial name
- PRELARS (NCT04612569)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Donostia
Preterm Labor
Uterocervical Angle in Idiopathic Polyhydramnios
To evaluate the performance of uterocervical angle (UCA) in the prediction of preterm labor in isolated polyhydramnios
- Trial name
- NCT03828695
- Testing
- uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL
Liver Fibrosis
Prediction of Significant Liver Fibrosis
The deep learning method based on convolutional neural network (CNN) was used to extract the relevant features of liver fibrosis classification from the multi-modal information of digital pathological sections, clinical…
- Trial name
- PSLF (NCT06509230)
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Huang Haijun
Knowledge, Attitudes, Practice
Determinants of Knowledge About and Use of Dietary Supplements
This study aims to evaluate (1) the level of knowledge about dietary supplements (KaDS) among people potentially interested in health issues in Poland and (2) the fraction of these people using dietary supplements (UoDS).
- Trial name
- NCT04184219
- Where
- Poland
- Volunteers
- 7,632 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz