Clinical trials: Prediction Model
NAFLD, Cardiovascular Diseases
Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: the Correlation Analysis and Risk Prediction Model Study
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the world. NAFLD is associated with a lot of comorbidity, such as diabetes, metabolic syndrome, coronary heart disease and chronic…
- Trial name
- NCT03534908
- Where
- China
- Volunteers
- 5,000,000 people, healthy volunteers welcome
- Sponsor
- Wuhan University
Head and Neck Cancer
Prediction of Outcome After Chemoradiotherapy for Head and Neck Cancer Using Functional Imaging and Tumor Biology
Despite uniform histopathological definition the response of locally advanced squamous cell carcinomas of the head and neck (HNSCC) to ionizing radiation differs greatly with locoregional recurrences burdening this patient…
- Trial name
- NCT01829646
- Testing
- functional MRI, Hypoxia gene expression profile., Functional MRI before start of treatment.
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke
Development of a Genomics-based Multimodal Prediction Model for Post-stroke Vascular Dementia
To collect large-scale multimodal data, including genomic information, neuroimaging, neurophysiological measures, cognitive assessments, and clinical characteristics from stroke survivors and healthy controls.
- Trial name
- NCT07660263
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Seyoung Shin
Gastric Cancer (GC), Premalignant Lesion
AI-Based Risk Prediction Model for Upper Digestive Tract Cancer
Upper digestive tract cancers are often preceded by pre-malignant lesions, but there is limited evidence regarding optimal risk prediction models and screening strategies for disease progression and cancer development.
- Conditions
- Gastric Cancer (GC), Premalignant Lesion, Gastric Intestinal Metaplasia, Atrophic Gastritis
- Trial name
- NCT07605312
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Genotype
AI-Driven Genotype Prediction Using EHR and Multimodal Data
The goal of this clinical study is to explore the potential of using electronic health records (EHR) and multimodal data (such as imaging, lab results, and clinical history) to predict a patient's genotype.
- Trial name
- NCT06791421
- Testing
- AI-Predictng Model
- Where
- 4 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Moyamoya Disease, Intracranial Hemorrhages
5T MRI and Metabolomics-Based Hemorrhage Risk Prediction in Moyamoya Disease
Intracranial hemorrhage is a leading cause of death and disability in patients with moyamoya disease (MMD), yet clinically available tools for predicting long-term hemorrhage risk are lacking.
- Conditions
- Moyamoya Disease, Intracranial Hemorrhages, Stroke
- Trial name
- NCT07781579
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Sport Injury, Hamstring Injury
System Dynamics Model for Acute Non-contact Lower Extremity Injuries Prediction
Despite the extensive research on prevention and prediction strategies, hamstrings strains injury (HSI) persists at a high rate in team sports and specifically in football.
- Conditions
- Sport Injury, Hamstring Injury, Risk Factors, Interaction
- Trial name
- SDLE (NCT05425303)
- Testing
- Exposure to risk for injury
- Where
- Greece
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Patras
Atherosclerosis, Prediction Model
Metabolomics Characterization of Biomarkers of ASCVD and Prediction Model
1. Describe the risk factors and metabonomics characteristics of atherosclerotic cardiovascular disease in Chinese patients. 2. Establish accurate prediction model of atherosclerotic heart disease.
- Trial name
- MEAL (NCT05148182)
- Where
- 2 sites in China
- Volunteers
- 1,869 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Age-related Hearing Loss
Prediction of Age-Related Hearing Loss Based on Comprehensive Risk Factors
This study aims to develop a predictive model for age-related hearing loss (ARHL) based on multi-source risk factors and artificial intelligence techniques.
- Trial name
- NCT07612618
- Testing
- Not applicable- observational study
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Infertility, Female, First Trimester Spontaneous Abortion
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.
This study will assess the predictive potential of circulating placental biomarkers for spontaneous miscarriage within the following month in an IVF setting.
- Trial name
- NCT04387994
- Testing
- Blood samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Left Ventricular Diastoic Dysfunction Cohort Study
Epidemic Profile of Left Ventricular Diastoic Dysfunction in the Community Elderly and Establishing Prediction Model: the Northern Shanghai Study
This study is one of the largest ongoing prospective population studies to evaluate target organ damages (TODs) and Left Ventricular Diastoic Dysfunction in the community-dwelling elderly Chinese, which is authorised and funded…
- Trial name
- ELITISM (NCT03735251)
- Testing
- Diuretic，Betaloc，antiplatelet drugs
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Ya-Wei Xu
Severe Early Childhood Caries, Caries
Construction of a Multidimensional Risk Prediction Model for Severe Early Childhood Caries
This study aims to address the high prevalence and recurrence rate of severe early childhood caries (S-ECC) by breaking away from the traditional single biological factor perspective and introducing the theories of "24-hour…
- Trial name
- NCT07335744
- Testing
- questionnaire survey
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Non-invasive Hepatocellular Carcinoma
Exploring the Knowledge, Attitudes, Behaviors and Perceived Barriers of Hepatologists Towards Non-invasive Hepatocellular Carcinoma Prediction Models in Hepatitis C Patients Who Achieved Sustained Virological Response Following Direct Acting Antivirals Therapy
This study aims to assess the knowledge, attitudes, and behaviors (KAB) of hepatologists regarding different models used to predict hepatocellular carcinoma (HCC) in patients with chronic hepatitis C (HCV) who achieved sustained…
- Trial name
- NCT06872047
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Placenta Praevia, Vaginismus
Transperineal Ultrasound to Assess the Progress of Labour
This is a prospective observational study of transperineal ultrasound between 24-42 weeks gestation and a prospective longitudinal observational study in all term (37-42 weeks) labouring women.
- Trial name
- NCT02430038
- Where
- United Kingdom
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Chronic Atrophic Gastritis
Objective Study on Tongue Diagnosis of Chronic Atrophic Gastritis
Chronic atrophic gastritis with intestinal metaplasia or dysplasia is called precancerous lesions of gastric cancer ( PLGC ). It is an important stage in the transformation of normal mucosa to gastric cancer and is significantly…
- Trial name
- NCT06489132
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Occupational Disidentification
Undergraduate Nursing Intern Cohort Study
This prospective observational cohort study aims to examine changes in occupational disidentification among undergraduate nursing interns during clinical internship and to identify factors associated with high-risk trajectories.
- Trial name
- NCT07682493
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Delirium
PROfylactic Haloperidol in Patients Defined as High Risk for DElirium With Delirium Risk mOdel
The hospital pharmacy at the Zuyderland Medical Centre developed the DElirium MOdel (DEMO) to predict which patients are at risk of developing a delirium in patients aged 60 or older.
- Trial name
- PRODEO (NCT03199950)
- Testing
- Haloperidol
- Where
- Netherlands
- Volunteers
- 1,366 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Anesthesiology, Anesthesiology Management
Machine Learning-Based Model for Individualized Drug Dose Prediction for Propofol
The goal of this observational study is to develop an individualized prediction model for drug dosage during propofol-induced loss of consciousness in anticipation of advances in research in this area.
- Trial name
- NCT06703879
- Testing
- Anesthesia induction with propofol
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Lipid Metabolism, Glucose Metabolism
Digital Twin - Modelling Postprandial Triglyceride and Glucose Responses
Giving personalised dietary advice will help mitigate the postprandial increases in TG and glucose levels, and will assist in the battle against the increase in nutrition-related diseases, such as cardiovascular diseases.
- Trial name
- NCT05313594
- Testing
- Mixed meal challenge test, MRI, DEXA
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Stroke, Acute Myocardial Infarction
Stroke Prediction Through Internet Search Queries
Cerebrovascular disease (stroke) is a leading cause of mortality and disability. Common risk assessment tools for stroke are based on the Framingham equation, which relies on traditional cardiovascular risk factors (e.g.…
- Trial name
- NCT04755959
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center