Clinical trials: Prediction Model
Cataracts
Low Cylinder Toric
Study evaluates the visual outcomes and patient satisfaction after implantation of a toric intraocular lens (IOL).
- Trial name
- NCT00732030
- Testing
- Toric IOL (SN60T3)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Alcon Research
Breast Cancer
Using Deep Learning Methods to Analyze Automated Breast Ultrasound and Hand-held Ultrasound Images, to Establish a Diagnosis, Therapy Assessment and Prognosis Prediction Model of Breast Cancer.
The purpose of this study is using a deep learning method to analyze the automated breast ultrasound (ABUS) and hand-held ultrasound(HHUS) images, establish and evaluate a diagnosis, therapy assessment and prognosis prediction…
- Trial name
- NCT04270032
- Testing
- ABUS and HHUS
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of the Fourth Military Medical University
Coronary Heart Disease (CHD), Heart Failure
a Foundational Model for Cardiovascular Disease Diagnosis and Prediction
The goal of this observational study is to develop and evaluate the efficacy of a foundational model that integrates multimodal medical data to improve the diagnosis and prediction of cardiovascular diseases in patients aged 18…
- Conditions
- Coronary Heart Disease (CHD), Heart Failure, Arrhythmias, Valvular Heart Disease
- Trial name
- NCT06591923
- Testing
- No Interventions
- Where
- China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Stomach Neoplasms, Aged
Prediction Model for Advanced Gastric Cancer in Elderly
This study aims to develop and validate a Nomogram (mCNS) model for predicting long-term survival in elderly patients following curative resection for advanced gastric cancer.
- Trial name
- NCT06467591
- Where
- China
- Volunteers
- 1,436 people
- Sponsor
- Chang-Ming Huang, Prof.
Atrial Fibrillation (AF)
Prediction of Atrial Fibrillation Using Polygenic Risk Score
The goal of this clinical trial is to learn whether a genetic risk score can help identify undiagnosed atrial fibrillation (AF) in adults who may have it.
- Trial name
- PREGENCE (NCT07641582)
- Testing
- 7-day continuous ECG patch monitor, Six-lead handheld electrocardiogram device, SNP array genotyping
- Where
- 5 sites in South Korea
- Volunteers
- 800 people
- Sponsor
- Seoul St. Mary's Hospital
Renal Neoplasms, Pathology
Optimising Renal Tumour Management Through Artificial Intelligence Modules
The goal of this observational study is to improve the management of people with renal tumour by multimodal artificial intelligence(AI). It will also measure the accuracy of the predictions from AI models.
- Conditions
- Renal Neoplasms, Pathology, Renal Cell Cancer
- Trial name
- NCT06714916
- Where
- China
- Volunteers
- 2,100 people
- Sponsor
- Shao Pengfei
Lung Adenocarcinoma
Radiomics Combined With Frozen Section Prediction Model for Spread Through Air Space in Lung Adenocarcinoma
a multifactorial model combining radiomics with frozen section analysis is a potential biomarker for assessing Spread Through Air Space during surgery, which can provide decision-making support to therapeutic planning for…
- Trial name
- NCT05400304
- Testing
- radiomics
- Volunteers
- 900 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Postoperative Delirium, Postoperative Neurocognitive Disorder
Risk Warning Model of Postoperative Delirium and Long-term Cognitive Dysfunction in Elderly Patients
The incidence of postoperative delirium in elderly patients is high, which can lead to long-term postoperative neurocognitive disorders. Its high risk factors are not yet clear.
- Conditions
- Postoperative Delirium, Postoperative Neurocognitive Disorder, Surgery
- Trial name
- NCT06423547
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Neonatology
Optimization and Clinical Study of Early Prediction Model for Neonatal Acute Respiratory Distress Syndrome
The goal of this observational study is to learn about neonatal acute respiratory distress syndrome in describe participant population.
- Trial name
- NCT05647850
- Testing
- No intervention
- Where
- 2 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University-Town Hospital of Chongqing Medical University
Organoid
Clinical Study on Drug Sensitivity Verification or Prediction of Therapy for Breast Cancer by Patient-Derived Organoid Model
This is a single center, single arm, open and exploratory clinical study, with 50 cases planned for a period of 2 years. The purpose of this study is to evaluate the consistency and accuracy of Patient-Derived Organoid Model of…
- Trial name
- NCT03544047
- Testing
- Paclitaxel
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College
Cervical Cancer, Radiotherapy
MRI-based Signatures for Survival Prediction in Cervical Cancer With Radiotherapy
This study aims to validate the value of tumor involvement features based on MRI in cervical cancer, facilitate the development of a more appropriate model for risk stratification, and help patients with varying risk profiles…
- Conditions
- Cervical Cancer, Radiotherapy, Prognostic Model, MRI
- Trial name
- NCT06197126
- Testing
- Treatment mainly composed of external pelvic beam radiotherapy (EBRT) followed by individualized high-dose-rate intracavitary brachytherapy (HDR-ICBT) .
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fujian Cancer Hospital
Rectal Cancer
Validation of a Predictive Model After Complete Response in Rectal Cancer
Background of the study: Prediction of rectal tumor response after chemoradiotherapy (CRT) might be helpful in individualizing treatment strategies, i.e., selecting patients who need less invasive surgery or another radiotherapy…
- Trial name
- Thunder (NCT00969657)
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Maastricht Radiation Oncology
Hypertensive Disorder of Pregnancy, Pregnancy Complications
The Investigation of the Prediction Model and Prevention Strategy of Serious Pregnancy Complications in Hypertensive Disorders of Pregnancy Based on the Chinese Population
1. Evaluation of the efficacy of aspirin in preventing preeclampsia and its serious complications during pregnancy and postpartum. 2.
- Trial name
- HDP-RPP (NCT05089175)
- Testing
- Low-dose aspirin
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Myocardial Infarction
Development and Validation of a Risk Prediction Model for Ischemic Stroke in Acute Myocardial Infarction Without Comorbid Atrial Fibrillation
Study Goal: This observational study aims to develop a tool to predict the risk of ischemic stroke(stroke caused by a blood clot) in people who survive a heart attack and do not have irregular heartbeats (atrial fibrillation) .
- Trial name
- NCT07171892
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Acute Kidney Injury, Liver Transplantation
Development and Validation of a Clinical Risk Prediction Model for Early Acute Kidney Injury Within 48 Hours After Liver Transplantation
Acute kidney injury (AKI) is a common complication after liver transplantation, with an incidence of 12.7-95%. The occurrence of acute kidney injury after transplantation is related to the poor prognosis of patients, which…
- Conditions
- Acute Kidney Injury, Liver Transplantation, Model
- Trial name
- NCT06750770
- Testing
- KDIGO CRITERIA
- Where
- China
- Volunteers
- 453 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Venous Thromboembolism, Critical Illness
Predicting the Risk of Venous Thromboembolism in Critically Ill Patients
Introduction: Venous thrombosis (VTE), including both deep vein thrombosis (DVT) and pulmonary embolism (PE) remains a frequent complication in patients admitted to the Intensive Care Unit (ICU).
- Trial name
- NCT05498142
- Volunteers
- 7,600 people
- Sponsor
- University Medical Center Groningen
Kidney Cancer
Risk-based Screen and Prognostic Analysis for Second Primary Malignancies in Kidney Cancer Patients
Second primary malignancy (SPM) significantly impacts the survival and prognosis of patients. This study endeavors to identify risk and prognostic factors associated with SPM after first primary kidney cancer and construct…
- Trial name
- NCT06531629
- Testing
- Surgery, radiation therapy and chemotherapy
- Where
- China
- Volunteers
- 72,408 people
- Sponsor
- Peking University First Hospital
Neuroblastoma (NB), Prognosis
Risk Model for Metastasis Detection of Neuroblastoma
Neuroblastoma (NB) is the most common extracranial solid tumor in children, accounting for about 15% of tumor-related mortality.
- Conditions
- Neuroblastoma (NB), Prognosis, Bone Marrow Metastasis, Bone Metastases
- Trial name
- NB (NCT06703944)
- Testing
- risk model in diagnosis and prognosis
- Where
- 3 sites in China
- Volunteers
- 500 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Orthopedic Procedures, Pain, Postoperative
Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care…
- Conditions
- Orthopedic Procedures, Pain, Postoperative, Surgery, Nerve Block
- Trial name
- NCT05018104
- Testing
- This is not an interventional study
- Where
- Canada
- Volunteers
- 1,270 people
- Sponsor
- University of British Columbia
Muscle Injury, Sprains and Strains
The Role of Periodic Health Examination in Determining Indirect Muscle Injury Risk in Elite Football (Soccer)
Preseason periodic health examination (PHE) is used routinely in elite football (soccer) and can be used to inform injury prevention strategies. Indirect muscle injuries (IMI) are a considerable burden to elite teams.
- Trial name
- NCT03782389
- Testing
- Preseason Periodic Health Examination Completion
- Volunteers
- 321 people
- Sponsor
- Manchester United Football Club