Clinical trials: Pregabalin
Fibromyalgia
Pregabalin In Adolescent Patients With Fibromyalgia
The main purpose of this study is to evaluate the long-term safety of pregabalin in adolescent patients who participated in the previous fibromyalgia study (A0081180) and who wish to recieve open-label pregabalin
- Trial name
- NCT01020526
- Testing
- pregabalin
- Where
- 26 sites in United States, Czechia and 1 more
- Volunteers
- 63 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Non-diabetic Painful Peripheral Polyneuropathy, Postherpetic Neuralgia (PHN)
A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment
This study is comparing the efficacy and tolerability of Qutenza with that of pregabalin in patients suffering from peripheral neuropathic pain.
- Conditions
- Non-diabetic Painful Peripheral Polyneuropathy, Postherpetic Neuralgia (PHN), Peripheral Nerve Injury (PNI)
- Trial name
- ELEVATE (NCT01713426)
- Testing
- Qutenza, Pregabalin
- Where
- 98 sites in Armenia, Austria and 20 more
- Volunteers
- 568 people
- Sponsor
- Astellas Pharma Europe Ltd.
Healthy
Non-interaction Study Between Pregabalin and Tramadol, Administered Individually or Combination, in Healthy Subjects
The study was carried out in the Clinical Unit and Analytical Unit of the Department of Pharmacology and Toxicology of the Faculty of Medicine of the Universidad Autónoma de Nuevo León, with the aim of comparing the…
- Trial name
- NCT05389150
- Testing
- Fixed dose combination Pregabalin 150 mg / Tramadol 50 mg, Pregabalin 150mg, Tramadol 50 mg
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Inguinal Hernia, Postoperative Pain
Efficacy of Pre-operative Oral Pregabalin in Ambulatory Inguinal Hernia Repair for Post Operative Pain
The study carry out is to determine whether the use of oral pregabalin premedication to assess the analgesic efficacy, opiod sparing, adverse effect and clinical value in post-operative pain management.
- Trial name
- NCT01450345
- Testing
- Pregabalin
- Where
- Malaysia
- Volunteers
- 72 people
- Sponsor
- University of Malaya
Peripheral Neuropathic Pain
Post-marketing Surveillance (PMS) to Observe the Safety and Effectiveness of Lyrica CR Extended Release Tablets
This is an open-label, non-comparative, non-interventional, prospective, and multi-center PMS study to observe safety and effectiveness of Lyrica CR (82.5mg, 165mg, 330mg) in Korean subjects under the actual condition of use.
- Trial name
- NCT04171453
- Testing
- Lyrica CR (Pregabalin)
- Where
- 3 sites in South Korea
- Volunteers
- 600 people
- Sponsor
- Viatris Korea
Overactive Bladder
Investigation of Tolterodine, Pregabalin and a Tolterodine - Pregabalin Combination for the Treatment of Overactive Bladder
Tolterodine is approved for use in the treatment of overactive bladder (OAB). The study is designed to a investigate whether pregabalin may have efficacy in OAB and whether the efficacy is altered when it is combined with…
- Trial name
- NCT00746681
- Testing
- Tolterodine & Pregabalin, Tolterodine, Pregabalin
- Where
- 23 sites in Czechia, Lithuania and 4 more
- Volunteers
- 188 people
- Sponsor
- Pfizer
Healthy
An Investigation of the Effects of Erythromycin on the Pharmacokinetics of the Pregabalin Controlled Release Tablet
The purpose of this study is to 1) evaluate the extent of absorption of a single dose of a pregabalin controlled release tablet with and without coadministration of erythromycin and 2) evaluate the safety and tolerability of a…
- Trial name
- NCT01342198
- Testing
- Pregabalin controlled release, 330 mg, erythromycin
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
Bioequivalence Study of Two Formulations of Pregabalin CR(Controlled-release) Table 300 mg
The purpose of this clinical trial is to (1) evaluate the bioequivalence(BE) of GLA5PR GLARS-NF3 tablet 300mg administered regular diet relative to GLA5PR GLARS-NF1 tablet 300mg administered regular diet and (2) determine the…
- Trial name
- NCT02952937
- Testing
- GLA5PR GLARS-NF3 tablet 300mg, GLA5PR GLARS-NF1 tablet 300mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Dacryocystitis
Analgesic Efficacy of Pre-operative Oral Pregabalin in Dacryocystorhinostomy Surgery
This study is conducted to evaluate the effects of preoperative oral pregabalin on postoperative pain and analgesic requirements in patients undergoing DCR surgery.
- Trial name
- NCT05455944
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
Neuropathic Pain, Insomnia
Sleep and Neuropathic Pain - Intervention Study on Pregabalin
The goal of this clinical study is to study sleep and its microstructure in neuropathic pain patients who have or who do not have a clinically significant sleep disturbance, before and during (after 1-month stabile dosage)…
- Conditions
- Neuropathic Pain, Insomnia, Sleep Disorder
- Trial name
- NCT06155916
- Testing
- Pregabalin
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Helsinki University Central Hospital
Diabetic Peripheral Neuropathic Pain
Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain Who Had an Inadequate Response to Pregabalin
Investigate the efficacy and safety of HSK16149 capsule in Chinese patients with Diabetic Peripheral Neuropathic Pain (DPNP) who had an inadequate response to Pregabalin, following 4 weeks treatment in comparison to Pregabalin
- Trial name
- NCT06490484
- Testing
- HSK16149 20mg BID, Pregabalin 150mg BID
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Chemotherapy-induced Peripheral Neuropathy
Memantine XR and Pregabalin for Chemotherapy-Induced Peripheral Neuropathy
Study is designed to assess the efficacy and safety of memantine XR and pregabalin in reducing neuropathic pain in patients with chemotherapy-induced peripheral neuropathy (CIPN) caused by prior treatment with any chemotherapy as…
- Trial name
- NCT03709888
- Testing
- Memantine XR-pregabalin combination therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Saint John's Cancer Institute
Neuralgia
P4 (Pregabalin for Peripheral Posttraumatic Pain)
To evaluate the efficacy of pregabalin compared to placebo in the treatment of posttraumatic peripheral neuropathic pain
- Trial name
- P4 (NCT00292188)
- Testing
- pregabalin
- Where
- 44 sites in Belgium, Canada and 9 more
- Volunteers
- 255 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Generalized Anxiety Disorder
Pregabalin in the Treatment of Patients With Generalized Anxiety Disorder (GAD).
The primary objective of this study is to evaluate the efficacy of pregabalin as compared to placebo in the treatment of patients with general anxiety disorder (GAD).
- Trial name
- NCT00413010
- Testing
- pregabalin
- Where
- 68 sites in United States, Czechia and 6 more
- Volunteers
- 356 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Chronic Pain
Chronic Pain Management After Herniorraphy
Nowadays, chronic pain mainly as a result of iatrogenic nerve damage is generally considered as the most frequent complication after inguinal hernia surgery.
- Trial name
- pregabalin (NCT00772291)
- Testing
- pregabalin
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- Erasmus Medical Center
Anesthesia
The Efficacy of Pregabalin on the Duration of the Spinal Anesthesia and the Early Postoperative Pain After Total Knee Arthroplasty
the purpose of this study is to evaluate the effectiveness of administration of pregabalin 2 hours preoperatively on the onset and the duration of the spinal anesthesia in total knee arthroplasty and the role of pregabalin in…
- Trial name
- NCT05071118
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Partial Seizures
Pregabalin In Partial Seizures (PREPS): An Open-Label, Multicenter Add On Therapy Trial
The purpose of this study is to assess the clinical improvement by partial seizures reduction, safety and tolerability of subjects having partial epilepsy related to the adjunction of pregabalin BID (75 to 300mg day titration…
- Trial name
- PREPS MEXICO (NCT00407797)
- Testing
- Pregabalin
- Where
- 8 sites in Mexico
- Volunteers
- 136 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuralgia, Postherpetic
A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgia
The purpose of this study is to evaluate efficacy and safety of pregabalin in the treatment of postherpetic neuralgia in a dose-ranging manner.
- Trial name
- NCT00394901
- Testing
- Pregabalin
- Where
- 39 sites in Japan
- Volunteers
- 372 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy Male and Female Subjects
Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in Chinese Healthy Subject
Y-4 is a new fixed-dose combination drug product containing two active ingredients of pregabalin and riluzole. The objective of the trial is to compare pharmacokinetic characteristics of Y-4 tablets with pregabalin capsules…
- Trial name
- NCT06935721
- Testing
- Y-4 tablet, Pregabalin capsule, Riluzole tablet
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Neuropathic Pain
Crisugabalin for Radiotherapy-Related Neuropathic Pain
The purpose of this study is to evaluate whether Crisugabalin has similar efficacy compared to Pregabalin in reducing radiotherapy-related neuropathic pain (RRNP) in patients with head and neck cancers.
- Trial name
- CRYSTAL (NCT06766916)
- Testing
- Crisugabalin, Pregabalin
- Where
- 11 sites in China
- Volunteers
- 172 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University