Clinical trials: Pregnancy, Ectopic
Non-Viable Pregnancy
Detection of Kisspeptins and miRNAs in Patients With Non-viable Pregnancy
Ectopic pregnancy (EP) is a pathology that affects 3%-16% of pregnancies in humans, being the main cause of morbidity and maternal mortality in the first trimester of pregnancy worldwide.
- Trial name
- TESTKM (NCT03877939)
- Testing
- Blood samples collection for analysis
- Where
- 2 sites in Spain
- Volunteers
- 433 people, healthy volunteers welcome
- Sponsor
- Vida Recoletas Sevilla
Ectopic Pregnancy, Laparoscopic
Cornual Wedge Resection Outcome
Cornual pregnancy is a rare form of ectopic pregnancy that accounts for 2% to 4% of ectopic pregnancies, with a mortality rate between 2.0% and 2.5%.
- Conditions
- Ectopic Pregnancy, Laparoscopic, Cornual Pregnancy
- Trial name
- NCT03974841
- Testing
- laparoscopic cornual resection
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pregnancy of Unknown Location
Hysteroscopy for the Diagnosis and Treatment of Pregnancy of Unknown Location
Infertility patients have a higher baseline risk of ectopic pregnancy compared to the general population. If an early pregnancy is not visible by ultrasound, patients with a pregnancy of unknown location (PUL) will undergo…
- Trial name
- NCT07469605
- Testing
- Hysteroscopy for diagnosis and treatment of pregnancy of unknown location
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Early Pregnancy, Ectopic Pregnancy
Kisspeptin Levels in Early Pregnancy
Kisspeptins are a family of neuropeptides that are critical for the puberty initiation and female fertility. The investigators aimed to investigate in this study kisspeptin levels in early pregnancy, ectopic pregnancy, and early…
- Trial name
- NCT04371991
- Testing
- blood test
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Semra Yuksel
Ectopic Pregnancy
The Effect of Different Treatment Modalities of Tubal Ectopic Pregnancy on Ovarian Reserve: a Prospective Cohort Study
Detect the effect of different treatment modalities of tubal ectopic pregnancy on ovarian reserve
- Trial name
- NCT06471166
- Testing
- Amh hormone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Tubal-preserving Treatment of Tubal Ectopic Pregnancy, Tubal Pregnancy
The Selection of Pregnancy for Patients After Tubal Ectopic Pregnancy Treatment
The incidence of re-ectopic pregnancy in patients with tubal ectopic pregnancy increases significantly, which may be related to the condition of the fallopian tubes, such as tubal inflammation, tubal obstruction and other…
- Conditions
- Tubal-preserving Treatment of Tubal Ectopic Pregnancy, Tubal Pregnancy, Pregnancy Preparation
- Trial name
- TSOPFPATEPT (NCT05498558)
- Testing
- No intervention.
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Persistent Pregnancy of Unknown Location, Ectopic Pregnancy
RCT for Women With a Persisting Pregnancy of Unknown Location
This is a randomized controlled trial to compare three currently available management strategies for women with a persisting pregnancy of unknown location (PPUL), which makes them at-risk for ectopic pregnancy.
- Trial name
- PPUL (NCT01800162)
- Testing
- Methotrexate, Uterine Evacuation, Expectant Management
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Pregnancy, Ectopic, Pregnancy, High Risk
Management of Pregnancies of Unknown Location (PUL)
In a randomized multicenter trial the investigators want to compare the ability of two hCG-based models in correctly classifying EPs as high risk among PULs and correctly classifying IUPs and failed PULs as low risk after two hCG…
- Conditions
- Pregnancy, Ectopic, Pregnancy, High Risk, Pregnancy Early
- Trial name
- NCT03461835
- Testing
- Risk classification of PUL by M4, Risk classification of PUL by NICE
- Where
- 3 sites in Sweden
- Volunteers
- 609 people
- Sponsor
- Göteborg University
Post-traumatic Stress Disorder, Miscarriage
Improving Mental Health Following Early PREgnancy Loss Using a Brief Cognitive Task
This is a randomised controlled trial designed to investigate the impact of a brief-cognitive task based intervention on intrusive memories, mental health symptoms and daily functioning, in women following an early pregnancy loss.
- Conditions
- Post-traumatic Stress Disorder, Miscarriage, Ectopic Pregnancy, Pregnancy Loss
- Trial name
- IMPREL (NCT05039853)
- Testing
- Brief cognitive task-based intervention
- Where
- United Kingdom
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pregnancy, Ectopic, Early Pregnancy Loss
Beta-HCG Levels in Uterine Cavity Lavage for Pregnancies of Unknown Location
The goal of this interventional study is to investigate the role of beta-hCG levels in uterine cavity lavage for differentiating between ectopic pregnancy and early pregnancy loss in female patients aged 18-45 years.
- Trial name
- BHCG-UCL-DEP (NCT07048587)
- Testing
- Beta-hCG levels in the uterine cavity lavage for differential diagnosis in pregnancy of unknown locations and ectopic pregnancy
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Pregnancy, Abdominal
Feasibility of a Non-invasive, Trans-abdominal, Low Cost Fetal Oximetry Probe on Pregnant Human Subjects
Three non-invasive, trans-abdominal fetal oximetry probes will be tested on pregnant human subjects, in order to obtain fetal heart rate.
- Trial name
- NCT03013842
- Testing
- Raydiant Oximetry Sensor System
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Davis
Ectopic Pregnancy
Reproductive Outcomes After a Previous Episode of Tubal Ectopic Pregnancy in Patients Managed Expectantly and Surgically
Although ectopic pregnancy was considered a leading cause of first-trimester maternal mortalities, current technological improvements allowed early diagnosis and opened a door for applying less invasive approaches.
- Trial name
- NCT05479786
- Testing
- Expectant management, Salpingectomy, Salpingostomy
- Volunteers
- 312 people
- Sponsor
- University of Palermo
Ectopic Pregnancy
Letrozole Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy
The aim of work is to study the effectiveness of letrozole in treatment of early undisturbed ectopic pregnancy in comparison with Methotrexate.
- Trial name
- NCT07624903
- Testing
- Methotrexate (drug), Letrozole 2.5Mg Tab
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Kafrelsheikh University
Pregnancy, Ovarian
Clinical and Live Birth Rates After Following Long Antagonist Protocol Versus Long Agonist Protocol
A prospective study of the evaluation of the clinical IVF (in vitro fertilization) results after following Long Antagonist protocol for Controlled Ovarian Stimulation (COS) versus following Long Agonist protocol
- Trial name
- NCT03693534
- Testing
- Clinical Pregnancy Rate
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Pregnancy, Ectopic
Serum VEGF as a Tubal Pregnancy Marker
The aim of the present study was (i) to evaluate whether a single measurement of VEGF would allow us to distinguish between intrauterine pregnancy (normal and abnormal) and EP and (ii) to correlate the levels of VEGF with serum…
- Trial name
- NCT02973230
- Testing
- Dosage of VEGF serum concentration
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Endstage Renal Disease
The Effect of Increasing Dialysate Magnesium on Calcification Propensity in Subjects on Haemodialysis
The purpose of this trial is to examine the effect of increasing dialyse magnesium on serum calcification propensity in subjects with end-stage renal disease treated with haemodialysis.
- Trial name
- NCT02977117
- Testing
- Dialysate magnesium (1.0 mmol/L), Dialysate magnesium (0.5 mmol/L)
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- Iain Bressendorff
Ectopic Pregnancy
Assessment of the Efficacy of Letrozole in the Treatment of Ectopic Pregnancy
In this study, about 150 women diagnosed with ectopic pregnancy who are referred to the Obstetrics and Gynecology Center of Valiasr Hospital are included in the study.
- Trial name
- NCT05918718
- Testing
- Letrozole, methotrexate
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Ectopic Pregnancy
Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications
Study Description (For Patients, Families, and Healthcare Providers) Purpose: The aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for…
- Trial name
- NCT07186127
- Testing
- Drug: Methotrexate (MTX) Patients received methotrexate treatment according to institutional protocols. Dosage and administration routes were recorded retrospectively. For patients who did not respond
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Bagcilar Training and Research Hospital
Genital Diseases, Female, Ectopic Pregnancy
Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-Up
The GYNAB study aims to compare patient satisfaction and clinical outcomes between dematerialized post-emergency gynecological follow-up using a connected health app and traditional in-person follow-up. Conducted by Drs.
- Conditions
- Genital Diseases, Female, Ectopic Pregnancy, Uncertain Viability of Pregnancy, Abortion, Missed
- Trial name
- GYNAB (NCT06615843)
- Testing
- Participants will receive post-emergency gynecological follow-up at home using a connected health app
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ectopic Pregnancy
Evaluation of Ipsilateral Tubal Patency After Conservative Medical or Surgical Treatment.
Ectopic Pregnancy is an entity in which a fertilized ovum is implanted outside its normal place, is considered a public health problem worldwide and is one of the main causes of maternal mortality in the first trimester.
- Trial name
- EENCBE (NCT05136274)
- Testing
- Medical treatment
- Where
- Angola
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- EDGREM Investimentos