Clinical trials: Pregnancy, Physical Activity
Hypertension, Pregnancy
Exercise in Pregnancy for Reduction of Blood Pressure in Obese Patients
Preeclampsia and other high blood pressure disorders of pregnancy are a significant cause of both maternal and fetal complications of pregnancy.
- Conditions
- Hypertension, Pregnancy, Preeclampsia, Exercise
- Trial name
- NCT01261884
- Testing
- Exercise support, Exercise intervention
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Solid Organ Transplant Rejection, Chronic Kidney Failure
Exercise Training and Kidney Transplantation
The goal of this clinical trial is to investigate the physiological and molecular effects of exercise training in transplant recipients. The main questions it aims to answer are: 1.
- Conditions
- Solid Organ Transplant Rejection, Chronic Kidney Failure, Quality of Life, Inflammation
- Trial name
- EXTRA (NCT06216015)
- Testing
- Exercise training, Continue exercising, Discontinue exercising
- Volunteers
- 345 people
- Sponsor
- Hugo de Luca Correa
Hypertension, Cardiovascular Risk Factor
Activity Trackers for Improving BP
The study aims to determine if use of physical activity trackers coupled with provider feedback will increase awareness of young adults of their physical fitness and improve blood pressure levels.
- Conditions
- Hypertension, Cardiovascular Risk Factor, Physical Activity, Chronic Kidney Diseases
- Trial name
- NCT03325426
- Testing
- FitBit
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of California, San Francisco
Breast Cancer
Pregnant Exposure to Persistent Organic Pollutants
Breast cancer, the first female cancer, affects one in eight women in her lifetime. The increase and uneven distribution of its prevalence throughout the world cannot be fully explained either by the increase in life expectancy…
- Trial name
- NCT03419026
- Where
- France
- Volunteers
- 155 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Metabolic Syndrome, CKD
Exercise Intervention in Patients With Metabolic Syndrome and Renal Disease: a Prospective Study
INTRODUCTION: Obesity (OB) and metabolic syndrome (MetS) are risk and progression factors for chronic kidney disease (CKD). However, the effect of OB/MetS intervention with exercise on renal function progression and proteinuria…
- Trial name
- EXRED (NCT06576518)
- Testing
- Therapeutic exercise
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of La Laguna
Postmenopausal; Menorrhagia, Physical Inactivity
Effects of Dietary Nitrate Intake on Physical Performance of Middle-aged Women
Through a randomized, crossover, triple-blind, placebo-controlled clinical trial, 15 physically inactive hypertensive women will participate a 8-day trial, each with two intervention protocols: 1) placebo and 2) beetroot; in…
- Conditions
- Postmenopausal; Menorrhagia, Physical Inactivity, Motor Activity
- Trial name
- NCT05820321
- Testing
- Beetroot juice rich in nitrate, Beetroot juice NO3 depleted
- Where
- 2 sites in Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Bladder Cancer, Quality of Life
Impacts and Testing of the "Multi-domains Active-living Program" in Operable Non-Muscle Invasive Bladder Cancer Patients
Among bladder cancer, the majority of them (70%) are non-muscle-invasive bladder cancer (NMIBC). The survival time is even longer in NMIBC. Patients with NMIBC receive surgery or transurethral resection of bladder tumor (TURBT).
- Trial name
- NCT05739968
- Testing
- Usual care + oncology case manager (OCM) care, Multi-domains Active-living Program (MAP) with e-health enhanced intervention + usual care + oncology case manager (OCM) care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Prostate Cancer
A Study of a Pelvic Floor Muscle Exercise Program Before and After Radical Prostatectomy
The researchers are doing this study to find out if a PFME program to reduce urinary incontinence after radical prostatectomy is feasible for people with prostate cancer.
- Trial name
- NCT06671782
- Testing
- Kegel exercises, Pelvic Floor Muscle Exercise Program with biofeedback, Questionnaires
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cardiovascular Disease, Chronic Kidney Disease
Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease
Introduction: Chronic kidney disease (CKD) is now an important public health issue. While 0.1% of the population is on dialysis, approximately 4.5% of subjects have renal dysfunction (glomerular filtration rate <60 ml/min/1.73…
- Conditions
- Cardiovascular Disease, Chronic Kidney Disease, Chronic Renal Disease, Hypertension
- Trial name
- NCT01155128
- Testing
- exercise aerobic
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Federal University of Pelotas
Neoplasms
An Open-label, Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK3326595 in Participants With Solid Tumors and Non-Hodgkin's Lymphoma
This first time in human (FTIH) open-label, dose escalation study will assess the safety, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical activity of GSK3326595 in participants with advanced or recurrent…
- Trial name
- Meteor 1 (NCT02783300)
- Testing
- GSK3326595, Pembrolizumab
- Where
- 15 sites in United States, Canada and 2 more
- Volunteers
- 297 people
- Sponsor
- GlaxoSmithKline
Obesity, Pregnancy Related
The Role of Physical Activity During Pregnancy on Metabolic Function, Inflammation, and Maternal and Neonatal Outcomes
Maternal obesity during pregnancy is a serious public health concern as it contributes to inflammation, insulin resistance, and excessive gestational weight gain- all of which negatively impact maternal and neonatal health.
- Trial name
- NCT03504319
- Testing
- Exposure to high-fat smoothie
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Acute Kidney Injury
Effects of Rehydration During Physical Exercise on Acute Kidney Injury Biomarkers
Rehydration during and after physical exercise is essential to avoid acute kidney injury. Soft drinks are commonly used during exercise. High intake of carbohydrates is leading to obesity and metabolic disorders.
- Trial name
- NCT04310514
- Testing
- Fructose/glucose/xylitol/saccharose
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Urinary Tract Infection
Cipro® XR in Therapeutic Response and Activity (eXtRa) - Assessing Symptom Relief in Urinary Tract Infections
The primary objective of this clinical trial was to determine the time to improvement of the signs and symptoms (eg, dysuria, frequency, urgency, gross hematuria, suprapubic pain, hesitancy, low back pain) of acute…
- Trial name
- NCT00676533
- Testing
- Cipro XR (Ciprofloxacin, BAYQ3939)
- Where
- 40 sites in United States
- Volunteers
- 276 people
- Sponsor
- Bayer
Pregnancy Related
Effects of Progressive Resistance Training on Physical State Energy and Fatigue During Pregnancy.
The purpose of this study is to compare the effects of progressive resistance training on physical state energy and fatigue during pregnancy.
- Trial name
- NCT06086847
- Testing
- progressive resistant exercises
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Postpartum Sexual Dysfunction, Postpartum Depression
POSH-Ex: Physiotherapist-Led Telerehabilitation Exercise Programme for Postpartum Sexual Health
Postpartum women frequently experience impairments in sexual function, pelvic floor dysfunction, fatigue, and depressive symptoms, all of which may adversely affect their quality of life during the postpartum period.
- Conditions
- Postpartum Sexual Dysfunction, Postpartum Depression, Fatigue, Physical Activity
- Trial name
- POSH-Ex (NCT07747285)
- Testing
- POSH-Ex (Postpartum Sexual Health Exercise)
- Where
- Croatia
- Volunteers
- 84 people
- Sponsor
- University Medical Centre Ljubljana
HSV-2 Infection, HIV Infections
Impact Evaluation of a School-Based Sexuality and HIV Prevention Education Activity in South Africa
The purpose of this study is to evaluate the impact of the new South African Department of Basic Education (DBE) sexuality and HIV education program that uses scripted lesson plans and supporting activities and will be…
- Conditions
- HSV-2 Infection, HIV Infections, Pregnancy Related
- Trial name
- NCT04205721
- Testing
- School-based sexuality and HIV prevention scripted lesson plans
- Where
- South Africa
- Volunteers
- 23,061 people
- Sponsor
- University of North Carolina, Chapel Hill
Stress Urinary Incontinence
Neuromuscular Re-eduaction, Exercise and Electric Dry Needling vs. Neuromuscular Re-education and Exercise for Stress Urinary Incontinence
The purpose of this research is to compare two different approaches for treating patients with stress urinary incontinence: neuromuscular re-education, impairment-based exercise and electric dry needling versus neuromuscular…
- Trial name
- NCT03238716
- Testing
- Electric DN, NM Re-ed, Exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Lupus Nephritis
Disease Activity Biomarkers in Patients With Systemic Lupus Erythematosus
The aim of this research project is to better understand the origin and clinical significance of two lupus-specific "genetic signatures" (IFN signature and plasma cell signature) in patient subgroups with well-defined clinical…
- Trial name
- JD001 (NCT05443516)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Pregnancy
Promoting Appropriate Weight Gain Pregnant Women
The purpose of this study is to learn if engaging in group based phone counseling (GBPC) and an interactive physical activity monitoring system can help pregnant women gain an appropriate amount of weight during pregnancy.
- Trial name
- GRUVE (NCT04180878)
- Testing
- Intervention, Intervention 2
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
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