Clinical trials: Pregnancy, Physical Activity
Gestational Diabetes Mellitus in Pregnancy, Anxiety in Pregnancy
The Effect of Model-Based PMR Training on Anxiety and Blood Sugar Levels to Women With Gestational Diabetes
This research is a randomized controlled experimental study to evaluate the effects of PMR application based on HBM in terms of blood sugar and anxiety levels in women with GDM.
- Trial name
- GDM (NCT05611541)
- Testing
- Diet therapy, Progressive Muscle Relaxation training, Progressive Muscle Relaxation group, The group who received diet therapy and practiced their daily activities.
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ege University
Labor
Evaluation of Laborpro - a New Device for the Assessment of Progress of Labor
A clinical study was conducted to demonstrate the accuracy of the LaborPro System in measuring fetal head station (from the pelvic inlet), cervical dilatation, and fetal head position against manual/digital examination.
- Trial name
- NCT00827229
- Testing
- Labor Monitor
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Trig Medical Inc
Non-small-cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck
Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors
This is a first-in-human, Phase 1, open label, multicenter, multiple dose, dose escalation and dose expansion study intended to evaluate the safety, pharmacokinetic, pharmacodynamic, and potential clinical benefit of PF-07209960…
- Conditions
- Non-small-cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Renal Cell Carcinoma, Urothelial Carcinoma
- Trial name
- NCT04628780
- Testing
- PF-07209960
- Where
- 13 sites in United States
- Volunteers
- 37 people
- Sponsor
- Pfizer
Gestational Diabetes
Autonomic Nervous Activity in Women With Gestational Diabetes
Through complex hormonal pathways, insulin resistance can lead to the activation of the sympathetic nervous system, and vice versa. Schobel et al.
- Trial name
- NCT00867022
- Where
- Finland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Pregnancy Related
Response of Pulmonary Functions to Deep Breathing Exercise in Twin Pregnancy
this study is to investigate the response of pulmonary function to deep breathing exercise in twin pregnancy
- Trial name
- NCT06031220
- Testing
- deep breathing exercise inform of diaphragmatic and costal breathing
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Badr University
Mixed Urinary Incontinence, Stress Urinary Incontinence (SUI)
Augmenting Urinary Reflex Activity Study 4 (Including eXtended Indications)
Exploratory safety and feasibility study of personalized adaptive pudendal neuromodulation for mixed urinary incontinence and extended indications using an implanted (Picostim™ II) system.
- Conditions
- Mixed Urinary Incontinence, Stress Urinary Incontinence (SUI), Chronic Pelvic Pain, Urge Urinary Incontinence
- Trial name
- AURA-4X (NCT06885931)
- Testing
- Pudendal neuromodulation
- Where
- 7 sites in Belgium, Netherlands and 1 more
- Volunteers
- 86 people
- Sponsor
- Amber Therapeutics Ltd
Renal Cell Carcinoma, Cardiotoxicity
A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect)
While sunitinib can be very helpful to treat kidney cancer, these medications can also cause side effects, including heart damage.
- Conditions
- Renal Cell Carcinoma, Cardiotoxicity, Heart Failure, Hypertension
- Trial name
- SUPER (NCT01014065)
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- AHS Cancer Control Alberta
Gestational Hypertension, Prematurity
Effects of Exercise During Pregnancy on Maternal and Child Health: a Randomized Clinical Trial
The Pamela Study is a clinical trial carried out during pregnancy to assess the potential effects of physical activity during pregnancy among previously inactive women.
- Conditions
- Gestational Hypertension, Prematurity, Maternal Post-partum Depression, Maternal Post-partum Weight Retention
- Trial name
- PAMELA (NCT02148965)
- Testing
- Physical Exercise / Physical Activity
- Where
- Brazil
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Membranous Nephropathy
Interferon Alfa Therapy Based on Th17 Profile in Membranous Nephropathy
Membranous Nephropathy (MN) is a renal autoimmune disease mediated by autoantibodies. Current management is based on the use of immunosuppressive therapies.
- Trial name
- ALPHAGEM (NCT05941845)
- Testing
- Peginterferon Alfa-2A 180 MCG/ML Injectable Solution
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Disability Physical, Urinary Incontinence
Transversus Abdominis and Pelvic Floor Muscle Strengthening Exercise Program In Patients With Grade 1 Cystocele
Cystocele, a protrusion of the bladder, happens while the bladder descends into the vagina. There are more than one underlying causes for the development of cystocele ensuing in weak point of the muscles and the connective tissue…
- Conditions
- Disability Physical, Urinary Incontinence, Prolapse
- Trial name
- NCT05474495
- Testing
- Pelvic floor muscle training, Transverse abdominas strength training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Pregnancy
The Effectiveness of The Breathing Exercise On The Nausea, Vomiting And Breathing Exercise In Pregnancy
Aim: This study aimed to investigate the effectiveness of the breathing exercise on pregnancy-related nausea and vomiting and the quality of life in the early pregnancy period.
- Trial name
- NCT05780112
- Testing
- breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Inonu University
Kidney Diseases
Effects of Virtual Reality and Breathing Exercises on Hemodialysis Patients' Symptoms and Quality of Life
Purpose: This study aims to examine the effects of virtual reality glasses and breathing exercises on symptoms and quality of life in patients receiving hemodialysis treatment.
- Trial name
- NCT06968130
- Testing
- routine hemodialysis, Breathing Exercise, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Trakya University
Preterm Birth
Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm
Young adults born very preterm (32 weeks gestation or earlier) do not respond well to aerobic exercise training, meeting the recommendations set by the Physical Activity Guidelines for Americans, where they do not increase their…
- Trial name
- NCT06334107
- Testing
- Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Colorectal Cancer, Pancreatic Cancer
IDOV-Immune for Advanced Solid Tumors
This is a Phase I clinical trial evaluating an investigational treatment called IDOV-Immune, a type of oncolytic virus therapy, for adults with advanced solid tumors that have not responded to standard treatments.
- Conditions
- Colorectal Cancer, Pancreatic Cancer, Melanoma, Ovarian Cancer
- Trial name
- NCT06910657
- Testing
- IDOV-Immune (oncolytic vaccinia virus)
- Where
- 5 sites in United States, Australia
- Volunteers
- 78 people
- Sponsor
- ViroMissile, Inc.
Heart Failure With Preserved Ejection Fraction, Chronic Kidney Diseases
Enhancing the Natriuretic Peptide System in HFpEF
The purpose of this study is to look at the differences in how individuals with heart failure with preserved ejection fraction in the presence of chronic kidney disease (HFpEF-CKD) and exercise induced dyspnea without objective…
- Trial name
- NCT05279742
- Testing
- MANP, Sacubitril/Valsartan
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Horng Chen
Diabetes, Gestational
Effect of Strength-resistance Exercise in the Reduction of Gestational Diabetes in Pregnant Women with Overweight or Obesity
The aim of this trial is to test the efficacy of regular resistance exercise in early pregnancy to prevent gestational diabetes mellitus in overweight/ obese pregnant women.
- Trial name
- NCT05840497
- Testing
- Resistance exercise
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacion Miguel Servet
Urinary Incontinence, Muscle Strength
Combined Effects of Swiss Ball Exercises and Diaphragmatic Breathing in Pregnant Females
30 to 60 percent of the pregnant females experience stress urinary incontinence depending on various factors like trimester, parity and body weight.
- Conditions
- Urinary Incontinence, Muscle Strength, Quality of Life
- Trial name
- NCT07520396
- Testing
- kegels exercises, Diaphragmatic breathing
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Peritoneal Malignancy, Ovarian Cancer
Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy
People who are diagnosed with cancer of the colon/rectum/appendix/ovaries that spreads into the lining of the tummy and some ovarian cancers or people with pseudomyxoma peritonei can often undergo intensive treatment including…
- Conditions
- Peritoneal Malignancy, Ovarian Cancer, Rectum Cancer, Appendix Cancer
- Trial name
- PANO (NCT05305820)
- Testing
- Exercise, Nutrition
- Where
- 3 sites in Ireland
- Volunteers
- 36 people
- Sponsor
- Dublin City University
Healthy, Lupus Nephritis
Functional MRI in Lupus Nephritis
The primary objectives of the study are as follows: To develop and optimize a renal functional magnetic resonance imaging (MRI) protocol consisting of Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI), Blood-Oxygen…
- Trial name
- NCT01731054
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Biogen
Postpartum Disorder
Bladder Displacement During Abdominal and Pelvic Floor Exercises
This study evaluates the bladder base displacements during abdominal and pelvic floor exercises in postpartum women comparing to nulliparous women
- Trial name
- NCT04154527
- Testing
- Pelvic Floor and Abdominal Exercises
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Castilla-La Mancha
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