Clinical trials: Pregnancy; Infection
Endometriosis
ENDS (ENDometriosis & FuSobacterium) Unveiling the Contribution of Fusobacterium Infection to the Development of Endometriosis
This will be a clinical interventional longitudinal study, without pharmacological intervention/device evaluation. A control group would however be recruited for secondary objective 1 and 2.
- Trial name
- ENDS (NCT06368596)
- Testing
- Fusobacterium detection
- Where
- Italy
- Volunteers
- 845 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Urinary Tract Infection in Pregnancy
Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women
Prevalence of uro-genital infections during pregnancy move between 7% to 12% in developed countries, meanwhile in developing countries this figure moved between 14% and until 55%, such is the case of Mexico.
- Trial name
- UTIPregnant (NCT03362697)
- Testing
- Probiotics, Antibiotics
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
COVID-19
Covid 19 Vaccine Acceptance in Egyptian Pregnant Women
To determine vaccine acceptance and hesitancy attitudes toward coronavirus disease 2019 (COVID-19) vaccines in Egyptian pregnant women.
- Trial name
- NCT05258760
- Volunteers
- 1,100 people
- Sponsor
- Cairo University
Covid19
COVID-19 International Drug Pregnancy Registry
The objective of the COVID-19 International Drug Pregnancy Registry (COVID-PR) is to evaluate obstetric, neonatal, and infant outcomes among women treated with monoclonal antibodies or antiviral drugs indicated for mild…
- Trial name
- COVID-PR (NCT05013632)
- Testing
- Antiviral Agents, Monoclonal antibody
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Pregistry
HPV Infection, Cervical Cancers
Remote Resilience: Novel Applications of mHealth in Nicaragua's Cancer Control Program
The goal of this clinical trial is to test an mHealth intervention for cervical cancer prevention in under-screened women ages 25-64 on the Caribbean Coast of Nicaragua.
- Trial name
- NCT06921798
- Testing
- mHealth
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Type 2 Diabetes Mellitus (T2DM), Recurrent Urinary Tract Infections
Cranberry Proanthocyanidins and Lactobacilli for Recurrent UTI Prevention in Type 2 Diabetes
The purpose of this prospective, single-arm feasibility study was to evaluate the operational feasibility, tolerability, safety, and exploratory clinical outcomes of an oral supplement combining standardized cranberry…
- Trial name
- NCT07832409
- Testing
- Cranberry Proanthocyanidins and Lactobacilli
- Where
- Georgia
- Volunteers
- 100 people
- Sponsor
- National Institute of Endocrinology, Georgia
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Acute Kidney Failure, Acute Kidney Insufficiency
Kidney Precision Medicine Project (KPMP) - COVID-19 Protocol
Since its inception, KPMP has developed sophisticated protocols for collection and analysis of human kidney tissue, and for collection of biofluids.
- Conditions
- Acute Kidney Failure, Acute Kidney Insufficiency, Acute Renal Failure, Acute Renal Injury
- Trial name
- NCT05384899
- Where
- 4 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Washington
Infections, Cytomegalovirus, Cytomegalovirus Infections
Study of the Transmission of Cytomegalovirus (CMV) Infection From Mother to Foetus
This study is designed to evaluate maternal virological and immunological parameters to determine their ability to predict congenital cytomegalovirus (CMV) infection.
- Trial name
- NCT01251744
- Testing
- Blood sample, Cord blood sample, Saliva swab
- Where
- 9 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- GlaxoSmithKline
Pregnancy, Sexually Transmitted Disease
Performance and Safety Trial of an Innovative Female Condom (Wondaleaf®)
General objective: To assess the performance and safety profile of a novel innovative design of female condom (Wondaleaf®) among healthy married women.
- Trial name
- NCT02593214
- Testing
- Wondaleaf®
- Where
- Malaysia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
HIV Infections, Kidney Disease
A Study of Zidovudine in HIV-Infected Patients With Kidney Problems
To determine how zidovudine (AZT) for the treatment of HIV infection is metabolized and excreted or eliminated in patients with infected or diseased kidneys.
- Trial name
- NCT00000685
- Testing
- Zidovudine
- Where
- 2 sites in United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Shock, Septic
Comparison of Vasopressin and Other Pressors in Septic Shock
The purpose of this study is to compare the classical tactics in the treatment of septic shock (dopamine, noradrenalin and dobutamine) to the use of vasopressin as first choice pressor.
- Trial name
- NCT00269685
- Testing
- vasopressin
- Volunteers
- 20 people
- Sponsor
- Université de Sherbrooke
Urinary Tract Infections
Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis
This is a double-blind, randomized, double-dummy, comparative study in parallel groups of subjects presenting with recurrent cystitis (≥2 episodes within the past 6 months).
- Trial name
- NCT03379389
- Testing
- Methenamine + Methylthioninium, Methenamine + Methylthioninium + Acriflavine + Atropa belladona, Antibiotics
- Where
- Brazil
- Volunteers
- 284 people
- Sponsor
- Fundação Educacional Serra dos Órgãos
Vaginal Infection
Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users
To determine the effect of performing internal vaginal douching on the frequency and severity and type of vaginal infections in IUD users
- Trial name
- NCT03261804
- Testing
- relation between vaginal douching and vaginal infection
- Where
- Egypt
- Volunteers
- 604 people
- Sponsor
- Assiut University
Respiratory Viral Infections, Adverse Pregnancy Outcomes
APOs Associated With Respiratory Viral Infections Before and During Early Pregnancy
Adverse pregnancy outcomes (APOs) are a collection of conditions that have short-term and long-term effects of complications related to pregnancy and childbirth on pregnant women and their fetuses, including hypertensive…
- Trial name
- APO (NCT07257952)
- Volunteers
- 1,440 people
- Sponsor
- Shanghai General Hospital, China
Cervical Cancer, Cervical Dysplasia
Acceptability and Efficacy of Self-sampling for Cervical Cancer Screening: A Pilot Study
In Singapore, the current cervical cancer screening uptake among women in Singapore has remained at low 50% since its introduction in 2004.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- NCT03813576
- Testing
- Self-collected HPV vaginal swab
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Spinal Cord Injury, Neurogenic Bladder
Multifaceted Treatment of Catheter-related Urinary Tract Infection
The specific objective of this clinical trial is to demonstrate that a multifaceted approach for treatment for catheter-related urinary tract infection (UTI) in patients with spinal cord injury is effective and feasible.
- Conditions
- Spinal Cord Injury, Neurogenic Bladder, Urinary Tract Infection
- Trial name
- NCT00732238
- Testing
- Shortened course of antibiotic therapy, Standard Therapy
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- US Department of Veterans Affairs
Urinary Tract Infections
Measurement of Urinary Catabolites of PACs as Biomarkers of Consumption of Cranberry Extracts
The purpose of this cross over pilot study is to investigate the urinary catabolites of Proanthocyanidines (PACs) as biomarkers of cranberry extracts in healthy young women.
- Trial name
- CUPACS (NCT02087735)
- Testing
- Cranberry extract
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Laval University
Surgical Site Infection
Prevention of Surgical Site Infection After Cesarean Delivery
There are approximately 1.4 million cesarean deliveries in the United States each year, and an average of 1250 elective cesarean deliveries each year at the Brigham and Women's Hospital (BWH) in Boston, Massachusetts.
- Trial name
- CAPISSI (NCT02027324)
- Testing
- Chlorhexidine-alcohol group, Povidone-Iodine Group
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Common Infections, Urinary Tract Infections
VA Quality Enhancement Research Initiative (QUERI) CARRIAGE VAST
Antimicrobial-resistant and healthcare-associated pathogens are a global health threat. The goals of antimicrobial stewardship are to minimize unnecessary and inappropriate antimicrobial use as a means to combat antimicrobial…
- Conditions
- Common Infections, Urinary Tract Infections, Respiratory Tract Infections
- Trial name
- QUERI VAST (NCT07877662)
- Testing
- Videoconference Antimicrobial Stewardship Team
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Office of Research and Development