Clinical trials: Pregnancy, completed
Pregnancy, GBS
Clinical Evaluation of the ARIES Group B Streptococcus (GBS) Assay
The ARIES GBS Assay is a real-time PCR based qualitative test designed to detect Group B Streptococcus (GBS) nucleic acid from Lim Broth enriched vaginal-rectal specimen swabs obtained from pregnant women between 35 - 37 weeks…
- Trial name
- NCT02497430
- Where
- 5 sites in United States
- Volunteers
- 918 people, healthy volunteers welcome
- Sponsor
- Luminex Corporation
Infertility, Endometriosis
Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis
A Phase 3 clinical trial of oral GnRH antagonist pre-treatment for women with endometriosis who are undergoing IVF, with a primary outcome of live birth rate.
- Trial name
- PREGnant (NCT04173169)
- Testing
- Elagolix 200 MG
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- Yale University
Diabetic Nephropathy
Spironolactone in Diabetic Nephropathy
The aim of the study was to evaluate the renoprotective effect (i.e. albuminuria- and bloodpressure lowering effect) of spironolactone 25 mg o.d.
- Trial name
- NCT00317954
- Testing
- Spironolactone
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Steno Diabetes Center Copenhagen
Stress Urinary Incontinence
Trans-Obturator Tape Versus Trans-Vaginal Tape for Stress Urinary Incontinence in Women
Stress urinary incontinence (SUI) is a health concern for many women. The transvaginal tape (TVT) surgery has become a common procedure to address the problem. Another surgery is now available, trans-obturator tape (TOT).
- Trial name
- NCT00234754
- Testing
- TVT Surgery TOT Surgery
- Where
- Canada
- Volunteers
- 199 people
- Sponsor
- University of Calgary
Renal Failure
Crossover Study to Compare PK of Once Daily LCP-Tacro Tablets to Generic Tacrolimus Capsules Twice Daily.
Open label, prospective, single-center, randomized, two sequence, three period crossover study to compare the steady state pharmacokinetics of LCP-Tacro tables to generic tacrolimus capsules administered twice daily in stable…
- Trial name
- NCT01962922
- Testing
- LCP-Tacro, Tacrolimus -IR
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Veloxis Pharmaceuticals
Fallopian Tube Carcinoma, Fallopian Tube Carcinosarcoma
Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
This phase I trial studies the side effects and best dose of veliparib when given together with carboplatin, paclitaxel, and bevacizumab in treating patients with newly diagnosed stage II-IV ovarian epithelial, fallopian tube, or…
- Conditions
- Fallopian Tube Carcinoma, Fallopian Tube Carcinosarcoma, Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma
- Trial name
- NCT00989651
- Testing
- Bevacizumab, Carboplatin, Cisplatin
- Where
- 23 sites in United States
- Volunteers
- 431 people
- Sponsor
- National Cancer Institute (NCI)
Postpartum Hemorrhage
The Effect of Placental Cord Drainage on Postpartum Blood Loss
To determine if placental cord drainage decreases the blood loss after spontaneous vaginal delivery
- Trial name
- NCT05610345
- Testing
- Placental Blood Drainage, Placenta Blood Not Drained
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Clear Cell Renal Cell Carcinoma, Cervical Carcinoma
A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors
This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX131™ in subjects with relapsed or refractory solid tumors.
- Conditions
- Clear Cell Renal Cell Carcinoma, Cervical Carcinoma, Esophageal Carcinoma, Pancreatic Adenocarcinoma
- Trial name
- NCT05795595
- Testing
- CTX131
- Where
- 7 sites in United States
- Volunteers
- 19 people
- Sponsor
- CRISPR Therapeutics AG
Preterm Infant, Exposure to Radiofrequency
Impact of Chronic Exposure to Radiofrequency Electromagnetic Fields on Neurophysiological Development in the Preterm Neonate
The massive use of highly technological devices in Neonatal Intensive Care Units may expose preterm neonates to electromagnetic fields, especially radiofrequencies, at low doses but continuously and chronically.
- Trial name
- NeuroPrem-RF (NCT03928457)
- Testing
- Parental questionnaire, Daily continuous recording of radiofrequency exposure levels, Follow-up of daily infants environmental and clinical parameters
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Kidney Injury
Continuous Venovenous Hemodiafiltration Versus Sustained Low-efficiency Hemodialysis for Critically Ill Patients With Acute Kidney Injury in Intensive Care Unit
The investigators conducted a comparison trial between SLED and CRRT in critically ill patients to evaluate the outcome for all cause mortality at 30 day .
- Trial name
- NCT02879201
- Testing
- Slow efficiency dialysis
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Hemodialysis, End Stage Renal Disease
Eplerenone in Hemodialysis Trial
Forty percent of patients that require dialysis for kidney failure die within three years mostly due to heart disease. Heart failure and high blood pressure are common problems in patients that require dialysis and are key causes…
- Trial name
- PHASE (NCT01650012)
- Testing
- eplerenone
- Where
- 5 sites in Canada
- Volunteers
- 158 people
- Sponsor
- McMaster University
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
S0306, Irinotecan in Treating Patients With Recurrent or Refractory Advanced Transitional Cell Cancer of the Urothelium Previously Treated With Chemotherapy
RATIONALE: Drugs used in chemotherapy such as irinotecan use different ways to stop tumor cells from dividing so they stop growing or die.
- Conditions
- Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00066612
- Testing
- irinotecan hydrochloride
- Volunteers
- 45 people
- Sponsor
- SWOG Cancer Research Network
Pregnancy, Ectopic
Serum VEGF as a Tubal Pregnancy Marker
The aim of the present study was (i) to evaluate whether a single measurement of VEGF would allow us to distinguish between intrauterine pregnancy (normal and abnormal) and EP and (ii) to correlate the levels of VEGF with serum…
- Trial name
- NCT02973230
- Testing
- Dosage of VEGF serum concentration
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Contraception
RAPID EC - Rct Assessing Pregnancy With Intrauterine Devices for EC
This study is a randomized trial of two IUDs for emergency contraception: the copper IUD, the most effective method of emergency contraception vs.
- Trial name
- NCT02175030
- Testing
- Copper IUD, Levonorgestrel IUD
- Where
- 6 sites in United States
- Volunteers
- 711 people
- Sponsor
- University of Utah
IgA Nephropathy
Additive Renoprotective Effects of Oral Calcitriol in IgA Nephropathy Patients Taking Renin-Angiotensin System Blockers
This study will help to show the efficacy of vitamin D and address the optimal strategy to minimize renal injury in IgAN patients.
- Trial name
- NCT01237028
- Testing
- Calcitriol
- Where
- 7 sites in South Korea
- Volunteers
- 168 people
- Sponsor
- Yonsei University
Kidney Injury
Advance Targeted Transfusion in Anemic Cardiac Surgical Patients for Kidney Protection: A Proof of Concept Pilot Study
One of the major complications of heart surgery is kidney injury, which occurs in up to 30% of patients and is associated with poor outcomes including death.
- Trial name
- NCT00861822
- Testing
- Advanced red blood cell transfusion
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Renal Cell Carcinoma
BMS-936558 (MDX-1106) In Subjects With Advanced/Metastatic Clear-Cell Renal Cell Carcinoma (RCC)
The purpose of this study is to measure how active BMS-936558 (nivolumab) is against Renal Cell Carcinoma (RCC) as measured by the disease not progressing and whether a dose response relationship exists.
- Trial name
- NCT01354431
- Testing
- nivolumab
- Where
- 41 sites in United States, Canada and 2 more
- Volunteers
- 168 people
- Sponsor
- Bristol-Myers Squibb
Immune Thrombocytopenia, Pregnancy
A Multicenter Study on Recombinant Human Thrombopoietin in Management of ITP in Pregnancy
The project was undertaking by Qilu Hospital of Shandong University and other well-known hospitals in China. Aims at evaluating efficacy and safety of rhTPO in management of ITP in pregnancy.
- Trial name
- NCT02391272
- Testing
- rhTPO
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Shandong University
Unintended Pregnancy, Family Planning
Addressing Reproductive Coercion in HEalth Settings - Kenya
The primary purpose of this research is to conduct a small matched cluster control trial of an intervention designed to address reproductive coercion and unintended pregnancy (ARCHES - Addressing Reproductive Coercion within…
- Conditions
- Unintended Pregnancy, Family Planning, Intimate Partner Violence (IPV)
- Trial name
- ARCHES (NCT03534401)
- Testing
- ARCHES Kenya
- Where
- United States
- Volunteers
- 659 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Schizophrenia, Renal Impairment
A Study of the Pharmacokinetics of ER OROS Paliperidone in Volunteers With Normal or Impaired Renal Function
The purpose of this study is to evaluate the pharmacokinetics of a single oral dose of 3 mg extended release paliperidone (ER OROSÃ' paliperidone) in patients with varying degrees of renal impairment (mild, moderate, and severe)…
- Trial name
- NCT00791401
- Testing
- ER OROS Paliperidone
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
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