Clinical trials: Pregnancy Abnormal
Placenta Accreta, Placenta Previa
Placenta Accreta New Detection Procedure by Rapid Assessment of Serum BNP
The placenta accreta is defined as a placenta that is abnormally adherent to the myometrium. It can thus invade the entire thickness of the myometrium (placenta increta) or even exceed the serosa and invade neighboring organs…
- Conditions
- Placenta Accreta, Placenta Previa, Normal Pregnancy
- Trial name
- PANDORA (NCT04215484)
- Testing
- serum BNP assessment
- Where
- Tunisia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ben marzouk Sofiene
Fetal Conditions, Maternal; Procedure
A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures
In this research study, the investigators want to learn more about the role of new innovative surgical devices, the Karl Storz Curved and Straight Fetoscopes for in-utero surgery.
- Conditions
- Fetal Conditions, Maternal; Procedure, Pregnancy Related, Twin to Twin Transfusion Syndrome
- Trial name
- NCT06056635
- Testing
- Karl Storz Curved Scope, Karl Storz Straight Scope
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Cervical Intraepithelial Neoplasia Grade 2/3, High-risk HPV (Any Strain)
Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3)
This phase I research protocol is designed to assess immunogenicity and clinical endpoints in patients with human papillomavirus (HPV) 16 cervical intraepithelial neoplasia (CIN)2/3.
- Trial name
- NCT02354534
- Testing
- Artesunate Suppositories
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Abnormal Labor, Complication of Delivery
Clinical Application of Intrapartum Ultrasound
Intrapartum ultrasound monitoring is to be compared with conventional labor monitoring to clarify the accuracy of this technology, and then provide a basis for later related research.
- Trial name
- IPUS (NCT06442735)
- Testing
- intrapartum ultrasound, vaginal examination
- Where
- China
- Volunteers
- 455 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Placenta Accreta
Creatine Kinase Versus 3D Doppler for Antenatal Diagnosis of Abnormal Adherent Placenta.
Placenta accreta is a potentially life-threatening obstetric condition that requires a multidisciplinary approach to management.Diagnosis of placenta accreta before delivery minimizes potential maternal or neonatal morbidity and…
- Trial name
- NCT03224780
- Testing
- maternal serum creatine kinase, 3D Doppler ultrasound
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Pregnancies of Unknown Location (PUL)
A Prospective Study of Misoprostol Administration in Asymptomatic Patients With Pregnancies of Unknown Location
A randomized prospective double blind study of misoprostol administration in asymptomatic patients with pregnancies of unknown location.
- Trial name
- amalis (NCT02581761)
- Testing
- CYTOTEC
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
IgA Nephropathy
Prospective Study of TW in Treatment of IgAN With Asymptomatic Abnormal Urinalysis
The purpose of this study is to: 1. To evaluate the latest effects of TW for IgA nephropathy (IgAN) with asymptomatic abnormal urinalysis. 2. To evaluate the safety and tolerability of TW.
- Trial name
- NCT00885547
- Testing
- tripterygium wilfordii (TW)
- Volunteers
- 90 people
- Sponsor
- Nanjing University School of Medicine
Endometrial Disease
Intrauterine Saline Washing for Detection Endometrial Disease in Patients With Abnormal Uterine Bleeding
Investigator will examined the diagnostic effect of the endometrial washing by saline. Because this technique more less painful and easier compared to endometrial curettage. Participants will separate into two groups.
- Trial name
- NCT02691715
- Testing
- Endometrial saline plus curettage, Endometrial curettage
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease
The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital
This prospective observational study aims to evaluate the learning curve of obstetrics and gynecology residents performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) hysterectomy in a university hospital…
- Conditions
- Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease, Adenomyosis of Uterus, Uterine Leiomyomas
- Trial name
- LC of V-NOTES (NCT07465822)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Cukurova University
Adenomyosis, Abnormal Uterine Bleeding
Adenomyosis: Genomic Mechanisms and Biological Response
Examination of genomic and biologic responses to LNG-IUS in patients with adenomyosis.
- Trial name
- NCT03428854
- Testing
- LNG-IUS
- Sponsor
- University of Texas Southwestern Medical Center
Asherman Syndrome, Atrophic Endometrium
Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium
This study will assess the use of autologous bone marrow stem cells mobilization using 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane (PLERIXAFOR) as an effective medical therapy for the treatment of…
- Conditions
- Asherman Syndrome, Atrophic Endometrium, Recurrent Implantation Failure
- Trial name
- NCT05343572
- Testing
- Plerixafor
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hugh Taylor
Postpartum Hemorrhage
RUBY Post-Market Registry on the Jada® System
The RUBY Study is a multicenter, observational, post-market registry designed to collect observational data on patients treated with the Jada System in the post-market setting.
- Trial name
- RUBY (NCT04995887)
- Testing
- Jada® System
- Where
- 16 sites in United States
- Volunteers
- 809 people
- Sponsor
- Alydia Health
Infertility, Female
The Potential Effects of Inofolic Plus on Abnormal Ovarian Reserve Parameters in Subfertile Women
Dr. Roseff and his colleagues are conducting a study to evaluate the effectiveness of a novel substance (Inofolic Plus®) in improving oocyte (egg) parameters in subfertile female patients, as measured through Anti-Mullerian…
- Trial name
- NCT01290432
- Testing
- Inofolic Plus
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Palm Beach Center for Reproductive Medicine
Abnormal Labor, Failed Induction of Labor
Enhanced vs. Routine Clear Liquid Intake in Labor
The goal of the study is to see if the addition of a carbohydrate- and protein-enhanced gel during labor speeds labor and reduces the rate of cesarean delivery.
- Conditions
- Abnormal Labor, Failed Induction of Labor, Ketosis
- Trial name
- NCT02524002
- Testing
- Accel Gel, Usual clear diet
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Temple University
Endometrial Cancer
Detection of Endometrial Cancer Through Risk Modelling
The study goal is to investigate a non-invasive approach to predict endometrial cancer (EC) risk, better understand disease progression and identify opportunities for intervention.
- Trial name
- DETECTR (NCT06268626)
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pregnancy
Advanced Fetal Imaging - Phase II
The goal of Advanced Fetal Imaging - Phase II is to advance fetal MRI imaging by designing MRI coils specifically for pregnant women and testing recently developed MRI image acquisition techniques.
- Trial name
- NCT02840019
- Testing
- Investigational MRI coil designed for pregnant women, MRI Scan
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Abnormal Uterine Bleeding, Postmenopausal Bleeding
Use of Nitrous Oxide During Office Hysteroscopy
The goal of this clinical trial is to assess the use of inhaled nitrous oxide during office hysteroscopy. The main questions it aims to answer are: Does it reduce pain during the procedure? Does it increase the success rate? Does…
- Conditions
- Abnormal Uterine Bleeding, Postmenopausal Bleeding, Endometrial Polyps, Retained Products of Conception
- Trial name
- NCT07074795
- Testing
- Inhalation of Nitrous Oxide (N₂O) during Office Operative Hysteroscopy, inhalation of ambient air during office hysteroscopy
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Maaynei Hayesha Medical Center
Uterine Fibroid
UA Versus UAE in Treatment of Fibroids
Study objective: To prove that Ulipristal acetate is an effective line of management for uterine fibroids by causing a significant decline in fibroid volumes resulting in a substantial relief of fibroid-related symptoms, and to…
- Trial name
- NCT04832906
- Testing
- Ulipristal Oral Tablet, Uterine artery embolization
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams Maternity Hospital