Clinical trials: Pregnancy Early
Effects of Chemotherapy
Assessing Fertility Potential in Female Cancer Survivors
Hypothesis: Girls and women exposed to chemotherapy and/or radiation therapy experience endocrine changes more similar to women in their late reproductive years than to same-age peers.
- Trial name
- NCT01143844
- Where
- 2 sites in United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pregnancy Complications Affecting Fetus (Diagnosis)
Maternal Serum Pentraxin 3 in Early Pregnancy to Predict Gestational Diabetes Mellitus
To investigate the association of maternal serum concentrations of pentraxin 3 in early pregnancy with gestational diabetes mellitus and to explore its potential value in the prediction of GDM.
- Trial name
- NCT03563638
- Testing
- 75gOGTT
- Volunteers
- 824 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Breast Neoplasms, Uterine Cervical Neoplasms
Early Detection of Cancers in Low Resource Countries
The purpose of this study is to implement a community-based combined program for early detection of breast, cervical, ovarian and endometrial cancer in low-resource countries delivered through a free standing or a mobile Well…
- Conditions
- Breast Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms
- Trial name
- NCT01178736
- Testing
- Breast Cancer Screening and Diagnosis, Cervical Cancer Screening and Diagnosis, Ovarian Cancer Screening and Diagnosis
- Where
- 3 sites in Brazil, Cambodia and 1 more
- Volunteers
- 36,000 people, healthy volunteers welcome
- Sponsor
- Woman's Cancer Foundation
Preterm Infant, Full-term Infant
A Novel Parent Education Program for Early Intervention
One in ten infants born in the USA is born preterm before 37 weeks of gestation and 50% of those will have motor and cognitive delays requiring intervention at school age.
- Trial name
- NCT04266717
- Testing
- Baby Play Intervention, Milestone Education
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Breast Cancer, Cervical Cancer
Community Clinic Model to Improve Early Detection of Breast and Cervical Cancers in Kenya
Kenya has a high incidence of breast and cervical cancers, and most women are diagnosed with late-stage disease. The investigators will conduct a study to assess the effectiveness and cost-effectiveness of strategies to increase…
- Trial name
- C3Link (NCT06572774)
- Testing
- C3Link Strategies
- Where
- Kenya
- Volunteers
- 5,400 people, healthy volunteers welcome
- Sponsor
- Implenomics
Fetal Growth Restriction, Placental Insufficiency
Patterns of Aortic Isthmus Doppler in Early Fetal Growth Restriction , and the Changes in Aortic Isthmus Doppler Parameters With Every Changes of Other Early Iugr Parameters Like EFW, Uterine Artery Doppler, Cerebroplacental Ratio and Ductus Venosus Doppler in Comparison With Normal Group .
This study aims to evaluate the patterns of aortic isthmus Doppler in fetuses diagnosed with early fetal growth restriction (FGR) and to correlate these findings with the severity of FGR and other Doppler parameters.
- Conditions
- Fetal Growth Restriction, Placental Insufficiency, Aortic Isthmus Doppler, Cerebroplacental Ratio
- Trial name
- NCT07676708
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preeclampsia
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9
Preeclampsia is a pregnancy related disease characterized by the new onset of hypertension and proteinuria after 20 weeks of gestation in previously normotensive women.
- Trial name
- NCT03258125
- Testing
- real time PCR (rPCR)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Perinatal Mortality, Cause of Neonatal Death
Verbal Autopsy to Assess Early Neonatal Death and Stillbirth
The NICHD Global Network (GN) for Women's and Children's Health Research, a multi-site, international research network, provides a unique infrastructure to implement an expanded perinatal verbal autopsy study using the FIRST…
- Conditions
- Perinatal Mortality, Cause of Neonatal Death, Cause of Stilbirth
- Trial name
- VA (NCT00640055)
- Testing
- Coordinator, Physician-assigned cause of death
- Where
- 4 sites in Guatemala, Pakistan and 2 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Endometriosis, Endometrioma
Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)
The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy
- Trial name
- NCT06847685
- Where
- 3 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure
Serum Phosphatemia Predictive Marker for AKI Diagnosis After Cardiac Surgery
Cardiac surgery associated acute kidney injury is an independent factor of morbidity and mortality . Despite its delayed elevation, serum creatinine (Cr) remains the goal standard to diagnose AKI.
- Conditions
- Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure, Complete Serum Creatinine Measure
- Trial name
- PhosphoIRA (NCT02900313)
- Testing
- cardiac surgery
- Where
- France
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Polycystic Kidney Disease
Early PKD Observational Cohort Study
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also…
- Trial name
- EPOC (NCT02936791)
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Infertility, Female
Randomized Trial Comparing Early "Trigger" Versus Delayed "Trigger" Timing in Cycles of Controlled Ovarian Stimulation.
This randomized trial will compare the efficacy of two different times of administration of medications for final oocyte maturation, commonly called a "trigger", in cycles of controlled ovarian stimulation (COS) for cycles in…
- Trial name
- NCT05498350
- Testing
- Ovulatory trigger timing
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Pediatric Obesity, Recruitment
The BEACH Interview Study- Pregnant and Breastfeeding Mothers
Interview pregnant and breastfeeding mothers in the Gainesville, FL area to optimize; clinical study recruitment and retention, patient-centered outcomes, and stool collection procedures.
- Trial name
- BEACH (NCT03036696)
- Testing
- Pregnant Mothers Interview, Breastfeeding Mothers Interview
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Florida
Congenital Adrenal Hyperplasia
Tweens to Teens Project at Penn State
The goal of this study is to help investigators to understand more about the development of characteristics related to being male or female (what is called gender development).
- Trial name
- T2T@PSU (NCT01184651)
- Testing
- Questionnaires/Interviews
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Penn State University
Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered
Preventing Childhood Obesity: A Two-pronged Approach Starting in Pregnancy and the First Year Postpartum
Our longitudinal aim is to reduce childhood obesity using our two-pronged intervention program, which includes healthy food choices and increased physical activity initiated during pregnancy and re-instated in the early period…
- Conditions
- Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered, Dietary Modification, Healthy Lifestyle Habits
- Trial name
- NCT01129505
- Testing
- Nutrition & Exercise Lifestyle Intervention Program (NELIP)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Stillbirth, Perinatal Death
A Feasibility Randomised Control Trial to Evaluate Early Perinatal Bereavement Counselling for Parents Who Have Experienced a Perinatal Death
The goal of this feasibility randomised control trial is to determine if a trial to evaluate perinatal bereavement counselling for parents who have experienced a perinatal death is feasible.
- Conditions
- Stillbirth, Perinatal Death, Psychological, Grief
- Trial name
- PEARL-C (NCT07494760)
- Testing
- Bereavement Counselling, Usual bereavement care
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Nurse's Role, Preterm Birth
The Effect of Kangaroo Father Care Transport on Preterm Infants
This study was planned to investigate the effect of paternal kangaroo care and transport on physiologic parameters, anxiety and paternal attachment in preterm infants.
- Conditions
- Nurse's Role, Preterm Birth, Fathers
- Trial name
- NCT06725914
- Testing
- kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zeynep Büşra GÜÇLÜ
Crohn Disease, Pregnancy
Modulating Early Life Microbiome Through Dietary Intervention in Crohn's Disease
The MELODY Trial: Modulating Early Life Microbiome through Dietary Intervention in Crohn's Disease, will test whether a non-invasive dietary intervention during pregnancy can improve the gut microbiota composition in both…
- Trial name
- NCT03850600
- Testing
- Diet-CD
- Where
- 2 sites in United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Vitamin D Deficiency
Nutritional Requirements for Vitamin D in Pregnant Women
Randomised, placebo-controlled dose-response intervention study with vitamin D3 in pregnant women.
- Trial name
- DMAT (NCT02506439)
- Testing
- 10 mcg Vitamin D3, 20 mcg Vitamin D3
- Where
- 2 sites in Ireland
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University College Cork
Preterm Birth
Progesterone to Prevent Preterm Delivery
Preterm birth (PTB) is a major challenge to perinatal health. It is defined as delivery before 37 completed gestational weeks. It accounts for 75% of perinatal deaths and more than 50% of long-term neurological disabilities, and…
- Trial name
- NCT03428685
- Testing
- Dydrogesterone Oral Tablet
- Where
- China
- Volunteers
- 1,714 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong