Clinical trials: Pregnancy Hemorrhage
Renal Stones, Nephrolithiasis
Efficacy of Tranexamic Acid on Blood Loss During Percutaneous Nephrolithotomy.
Efficacy of tranexamic acid on blood loss during percutaneous nephrolithotomy. a double-blind, placebo-controlled randomized clinical trial.
- Trial name
- NCT04367155
- Testing
- Tranexamic acid injection
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Perinatal Death, Respiratory Distress Syndrome, Newborn
Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities
Hyperoxygenation for resuscitation of abnormal fetal heart rate tracings has been routine obstetric practice. However, there have not been any studies to support this practice.
- Conditions
- Perinatal Death, Respiratory Distress Syndrome, Newborn, Hypoxic-Ischemic Encephalopathy, Neonatal Seizure
- Trial name
- NCT03996317
- Testing
- Room air
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Threatened Abortion, Pre-Eclampsia
Progesterone for First Trimester Vaginal Bleeding
The purpose of this study is to investigate whether treatment with progesterone for patients with first trimester vaginal bleeding will alter the rates of obstetrical complications and adverse pregnancy outcomes.
- Conditions
- Threatened Abortion, Pre-Eclampsia, Abruptio Placentae, Fetal Growth Retardation
- Trial name
- NCT01501890
- Testing
- dihydroxyprogesterone caproate
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Postmenopausal; Menorrhagia, Physical Inactivity
Effects of Dietary Nitrate Intake on Physical Performance of Middle-aged Women
Through a randomized, crossover, triple-blind, placebo-controlled clinical trial, 15 physically inactive hypertensive women will participate a 8-day trial, each with two intervention protocols: 1) placebo and 2) beetroot; in…
- Conditions
- Postmenopausal; Menorrhagia, Physical Inactivity, Motor Activity
- Trial name
- NCT05820321
- Testing
- Beetroot juice rich in nitrate, Beetroot juice NO3 depleted
- Where
- 2 sites in Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Hematuria, Benign Prostatic Hyperplasia
RADA16 for Aquablation Day Case
This is a pilot proof of concept single-arm study using PuraStat following Aquablation procedure to assess reduction of hematuria to allow for same day discharge.
- Conditions
- Hematuria, Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
- Trial name
- RAD (NCT06948331)
- Testing
- PuraStat
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
Obstetric Complication, Postpartum Hemorrhage
Antibiotics During Intrauterine Balloon Tamponade Placement
The goal of this study is to identify whether antibiotics given at the time of placement of an intrauterine balloon tamponade (IBT) will result in reduction of the risk of endometritis.
- Conditions
- Obstetric Complication, Postpartum Hemorrhage, Postpartum Endometritis
- Trial name
- NCT03478163
- Testing
- CeFAZolin 1000 MG, Clindamycin 900 MG in 6 ML Injection
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Cedars-Sinai Medical Center
Urologic Diseases, Prostate Cancer
Intravesical Antifibrinolytic for Patients With Hematuria and Clot Retention
A study looking at the feasibility of doing a full-scale RCT that investigates the use of tranexamic acid intravesically prior to continuous bladder irrigation treatment in the emergency department for urinary retention due to…
- Conditions
- Urologic Diseases, Prostate Cancer, Bladder Cancer, Urinary Retention
- Trial name
- NCT04555343
- Testing
- Tranexamic acid
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- Fraser Health
Immune Thrombocytopenia
Prednisone Plus IVIg vs. Prednisone for ITP During Pregnancy
This is a prospective, randomized, open-label, multicenter clinical trial study to compare the efficacy and safety of prednisone plus IVIg to prednisone monotherapy in the treatment of immune thrombocytopenia (ITP) in pregnancy.
- Trial name
- IVIg (NCT06577909)
- Testing
- Prednisone, IVIg
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Placenta Previa With Hemorrhage - Delivered, Placenta Accreta
A.Chohan Continuous Squeezing Suture (ACCSS) for Placenta Previa / Accreta
Placenta praevia and accreta spectrum disorders are rising in incidence due to increased rate of repeat caesarean sections. Peripartum hysterectomy remains the only definitive treatment of massive postpartum haemorrhage related…
- Trial name
- ACCSS (NCT04660578)
- Testing
- ACCSS
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- King Edward Medical University
Blood Loss, Surgical, Blood Loss, Postoperative
Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony
This research study is being done to learn what effect a single dose of calcium gluconate will have on blood loss at the time of cesarean delivery in pregnancy patients at high risk for uterine atony.
- Conditions
- Blood Loss, Surgical, Blood Loss, Postoperative, Uterine Atony
- Trial name
- NCT07217899
- Testing
- Calcium Gluconate, Saline
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Michigan
Polyvascular Disease, Atherosclerosis
Clinical Register Studying the therApeutic Patient Population With Multifocal Atherosclerosis
Аn international, multicenter, non-interventional real-life clinical practice Register studying the Actual therapeutic patient population with Multifocal Atherosclerosis in the Russian Federation and Eurasian countries
- Conditions
- Polyvascular Disease, Atherosclerosis, Atherosclerosis Generalized, Cardiovascular Diseases
- Trial name
- KAMMA (NCT05189847)
- Where
- Russia
- Volunteers
- 3,059 people
- Sponsor
- Eurasian Association of Therapists
Postpartum Hemorrhage
THUMB: Multi-centre Cluster Trial for Caesarean Section Haemorrhage
The quality improvement project evaluating the delivery of a perioperative care complex intervention to improve haemorrhage-related outcomes in patients undergoing caesarean section.
- Trial name
- NCT07005349
- Testing
- Quality improvement program
- Where
- South Africa
- Volunteers
- 2,400 people
- Sponsor
- Bruce Biccard
Thrombocytopenia, Postpartum Haemorrhage (PPH)
Prediction of Platelet Function Using Viscoelastic Test (ROTEM® Sigma) in Obstetric Anesthesia.
This prospective observational, non-interventional, single-center study aims to evaluate whether the viscoelastic parameter PLTEM, derived from ROTEM® sigma testing (EXTEM-A5 minus FIBTEM-A5), can accurately estimate platelet…
- Trial name
- NCT07616349
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- Nicolas Brogly
Uterine Atony, Uterine Atony With Hemorrhage
Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery
Postpartum hemorrhage (PPH) is the leading cause of maternal morbidity and mortality worldwide. Up to 80% of PPH is caused by uterine atony, the failure of the uterine smooth muscle to contract and compress the uterine…
- Conditions
- Uterine Atony, Uterine Atony With Hemorrhage, Postpartum Hemorrhage, Cesarean Section Complications
- Trial name
- CALBLOC (NCT05027048)
- Testing
- Calcium chloride
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Hysterectomy (MeSH nr: E04.950.300.399)
Transforming Global Surgery Capacity and Capability Through Affordable Virtual Reality
The goal of this randomized controlled trial was to evaluate whether Deliberate Virtual Reality (VR) training can improve surgical skills, knowledge, and confidence in performing postpartum hysterectomy among junior-level Zambian…
- Trial name
- NCT07403526
- Testing
- Deliberate Virtual Reality (VR) Training, Standard Clinical Training
- Where
- Zambia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Anemia
Menstruation and Anemia Research: A Community Health Study
This research is studying if a community-based, community health worker (CHW) led psychosocial intervention improves hemoglobin levels among Black/African American and/or Hispanic or Latino women with anemia compared to standard…
- Trial name
- MARCH (NCT07832526)
- Testing
- Standard of Care, Informational Series and follow-up support
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Mucositis, Graft-versus-host Disease
Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX
A comparative trial where all patients will receive daily doses of tacrolimus (TAC) until day +60 when tapering will begin, in the absence of graft-versus-host disease (GVHD), and discontinued by day +180.
- Trial name
- NCT00360685
- Testing
- Tac+MTX, TAC + MMF
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Uterine Fibroids, Heavy Menstrual Bleeding
Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids
The primary objective of this study is to demonstrate the superior efficacy versus placebo of OBE2109 alone and in combination with add-back therapy for the reduction of heavy menstrual bleeding associated with uterine fibroids…
- Trial name
- PRIMROSE 1 (NCT03070899)
- Testing
- OBE2109, Add-back
- Where
- 116 sites in United States
- Volunteers
- 526 people
- Sponsor
- ObsEva SA
Vaginal Bleeding, Loop Electrosurgical Excision
Use of Chitosan Powder in Loop Electrosurgical Excision Procedure
Early treatment of cervical intraepithelial neoplasia (CIN) II-III gives rise to a decrease in the incidence of invasive cervical cancer.
- Trial name
- NCT05661708
- Testing
- Chitosan
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
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