Clinical trials: Pregnancy Hemorrhage
Blood Loss
Validating a New Point-of-care Device for Estimation of Blood Count in Pregnant Women
Postpartum hemorrhage is a well-known complication of delivery and the leading cause of maternal mortality worldwide. In developed nations, a complete blood count (CBC) is commonly collected as a means to assess or base treatment…
- Trial name
- NCT05012202
- Testing
- Hemi device
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Post-partum Hemorrhage
Mostafa Maged Maneuver in Comparison With Bimanual Uterine Compression to Control Post-partum Hemorrhage
The current study aimed to investigate the effectiveness of the Mostafa Maged maneuver compared to Bimanual uterine compression in controlling postpartum hemorrhage during vaginal delivery.
- Trial name
- NCT06002256
- Testing
- Mostafa Maged maneuver, Bimanual uterine compression
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ministry of Health and Population, Egypt
Postpartum Hemorrhage, Carbetocin
Timing of Carbetocin Administration in Postpartum Hemorrhage
Postpartum haemorrhage (PPH) is one of the major contributors to maternal mortality and morbidity worldwide. Active management of the third stage of labour has been proven to be effective in the prevention of PPH.
- Trial name
- NCT06776926
- Testing
- Carbetocin
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mehmet Mete Kırlangıç
Metrorrhagia
An Open-Label Study to Compare the Bleeding Profile of Norelgestromin/Ethinyl Estradiol in an Extended Regimen to Norelgestromin/Ethinyl Estradiol Given in a Traditional Regimen
The purpose of this study is to compare the bleeding profile of norelgestromin/ethinyl estradiol given in an extended continuous regimen to norelgestromin/ethinyl estradiol given in a traditional cyclic regimen
- Trial name
- NCT00320580
- Testing
- norelgestromin/ethinyl estradiol
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Leiomyoma (Uterine Fibroids), Adenomyoma of Uterus
The Effect of Uterine Manipulator Use During Abdominal Hysterectomy on Postoperative Sexual Function
This prospective, single-center, randomized controlled trial aims to evaluate the effect of uterine manipulator use during total abdominal hysterectomy on postoperative female sexual function at 3 months, assessed by the Female…
- Conditions
- Leiomyoma (Uterine Fibroids), Adenomyoma of Uterus, Uterine Bleeding
- Trial name
- UMAH (NCT07431788)
- Testing
- Uterine Manipulator, Conventional Abdominal Hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erkan Gol
Very Low Birth Weight Infants, Premature Infants
Delayed Cord Clamping in Very Low Birth Weight Infants
The purpose of this study is to determine if there is a difference in neonatal outcomes with delayed umbilical cord clamping at 30 versus 60 seconds.
- Conditions
- Very Low Birth Weight Infants, Premature Infants, Intraventricular Hemorrhage
- Trial name
- DCC (NCT02337088)
- Testing
- Delayed cord clamping at 30 seconds, Delayed cord clamping at 60 seconds
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Chicago
Menorrhagia, Pelvic Pain
Randomized Clinical Trial Comparing Conventional Laparoscopic and Robot-Assisted Laparoscopic Hysterectomy
Robotic-assisted surgery is becoming more prominent within the specialty of Gynecologic surgery with little direct evidence that it is if not better than traditional laparoscopic surgery, at least equivalent.
- Conditions
- Menorrhagia, Pelvic Pain, Hysterectomy
- Trial name
- NCT02118974
- Testing
- Hysterectomy
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Milton S. Hershey Medical Center
Menorrhagia
Study of a Levonorgestrel 52 mg Intrauterine System for the Treatment of Heavy Menstrual Bleeding
To assess the efficacy of a levonorgestrel 52 mg intrauterine system as a treatment for heavy menstrual bleeding.
- Trial name
- NCT03642210
- Testing
- Levonorgestrel 52 mg intrauterine system
- Where
- 29 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Medicines360
Asymptomatic Microscopic Hematuria
Vaginal Estrogen for Asymptomatic Microscopic Hematuria
The specific aim of this protocol is to determine whether vaginal estrogen is an effective treatment for asymptomatic microscopic hematuria in postmenopausal women.
- Trial name
- NCT03033160
- Testing
- Estradiol Ring
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Boston Urogynecology Associates
Vaginal Bleeding
Long-Term Outcome Following Laparoscopic Supracervical Hysterectomy Performed With and Without Excision of the Endocervix in a Reverse Cone Pattern
The occurrence of persistent vaginal bleeding following laparoscopic supracervical hysterectomy (LSH) is reported in the wide range of 0 % - 25 %.
- Trial name
- LSH-LAPCONE (NCT00921778)
- Testing
- Lapcone, laparoscopic supracervical hysterectomy
- Where
- Norway
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Postpartum Hemorrhage
Effect of Prophylactic Administration of Oxytocin in Uniject™ on Postpartum Hemorrhage at Home Births in Ghana
This study is designed to test the hypothesis that the intramuscular administration of 10 IU of oxytocin in Uniject™ during the third stage of labor by a Community Health Officer (CHO) at home births in Ghana will reduce the risk…
- Trial name
- NCT01108289
- Testing
- Oxytocin in Uniject
- Where
- Ghana
- Volunteers
- 1,586 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Dysfunctional Uterine Bleeding
Effects of Tranexemic Acid Versus Norethisterone Acetate on Endometrial Vasculature .
Heavy periods is a significant problem in reproductive age .It affects about a third of women in the childbearing period Any of the following is considered to be heavy menstrual bleeding (Bleeding that lasts more than 7…
- Trial name
- NCT04290013
- Testing
- norethisterone acetate, tranexamic acid tablets
- Volunteers
- 120 people
- Sponsor
- Cairo University
Renal Insufficiency, Chronic, Heart Failure
Clinical Validation Through Analytical Study With Urine Samples to Compare the Effectiveness and Security of an Intelligent Device
The objectives of the Clinical Validation Through Analytical Study With Urine Samples to Compare the Effectiveness and Security of an Intelligent Device are: 1.To evaluate the performance of S-There Device in comparison to the…
- Conditions
- Renal Insufficiency, Chronic, Heart Failure, Diabete Mellitus, Diabetes; Nephropathy (Manifestation)
- Trial name
- STSD-2019-001 (NCT03965975)
- Testing
- Lab Gold Standard, S-There
- Where
- Spain
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- S-There Technologies SL
Urothelial Carcinoma
Investigation and Detection of Urological Neoplasia in Patients Referred With Suspected Urinary Tract Cancer:
Bladder cancer is common in the UK and can kill. A common sign of bladder cancer is blood in the urine (haematuria). GPs will refer to a specialist (Urologist) for further investigation of haematuria if they suspect cancer.
- Trial name
- IDENTIFY (NCT03548688)
- Where
- United Kingdom
- Volunteers
- 11,059 people
- Sponsor
- British Urology Researchers in Surgical Training
Postpartum Haemorrhage
Carbetocin Versus Syntometrine for the Third Stage of Labour
Intramuscular carbetocin is as effective as intramuscular syntometrine for the prevention of postpartum haemorrhage
- Trial name
- NCT00499005
- Testing
- Syntommetrine and Carbetocin
- Where
- Singapore
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Postpartum Hemorrhage, Vaginal Delivery
Reducing Postpartum Hemorrhage After Vaginal Delivery
Postpartum hemorrhage is the primary cause threatening the life safety of pregnant women in the world and China, and also the main cause of hysterectomy for women giving birth.
- Trial name
- NCT05501106
- Testing
- Integrated Improvement strategies
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Anovulatory Infertility, Abnormal Uterine Bleeding-Ovulatory Disorders
Effectiveness and Safety of Bushen Culuan Decoction for Anovulatory Infertility
This study is to evaluate the effectiveness and safety of Bushen Culuan Decoction in the treatment of anovulatory infertility, including anovulatory abnormal uterine bleeding, polycystic ovarian syndrome, hyperprolactinemia…
- Conditions
- Anovulatory Infertility, Abnormal Uterine Bleeding-Ovulatory Disorders, Polycystic Ovarian Syndrome, Hyperprolactinemia
- Trial name
- NCT03709849
- Volunteers
- 528 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Contraception
Mirena Extension Trial
The study is performed to assess if Mirena is effective and safe as a birth control method beyond 5 years of use. Further the menstrual blood loss (in women that had Mirena inserted for the indication heavy menstrual bleeding…
- Trial name
- MET (NCT02985541)
- Testing
- Levonorgestrel IUS (Mirena, BAY86-5028)
- Where
- 49 sites in United States
- Volunteers
- 364 people
- Sponsor
- Bayer
Postpartum Haemorrhage
Towards Better Prognostic and Diagnostic Strategies for Haemostatic Changes During Major Obstetric Haemorrhage
Major obstetric haemorrhage (MOH) remains a cause of significant maternal morbidity and mortality worldwide. By identifying women with a higher a priori risk of major haemorrhage during their pregnancy or early during postpartum…
- Trial name
- TeMpOH-2 (NCT02149472)
- Where
- Netherlands
- Volunteers
- 1,649 people, healthy volunteers welcome
- Sponsor
- Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research
Pain in Endometrial Biopsy, Abnormal Uterine Bleeding
The Effect of the Valsalva Maneuver in Endometrial Biopsy: A Randomized Controlled Trial
Endometrial sampling with a pipelle is a common procedure used to collect a small sample from the lining of the uterus. During the procedure, the cervix is sometimes held with a surgical instrument called a tenaculum, which may…
- Trial name
- NCT07496905
- Testing
- endometrial biopsy, Tenaculum Application, Valsalva Maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
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