Clinical trials: Pregnancy Hemorrhage
Anemia, Iron Deficiency, Heavy Menstrual Bleeding
IV Iron vs Oral Iron for Treatment of Anemia in Women With Abnormal Uterine Bleeding
This study investigates whether intravenous (IV) iron [Feraheme (ferumoxytol) injection)] is a better treatment than oral iron pills (ferrous sulfate) for correcting anemia in women who have heavy menstrual bleeding and anemia.
- Trial name
- NCT04205266
- Testing
- Ferumoxytol, Ferrous Sulfate
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Post Partum Hemorrhage
Predictability of Thromboelastography Parameters in Severe Post Partum Hemorrhage
The aim of the study is to determine if thromboelastography parameters can be predictive of severe post partum hemorrhage.
- Trial name
- NCT03449420
- Testing
- thromboelastography
- Volunteers
- 100 people
- Sponsor
- Hôpital Armand Trousseau
Uterine Leiomyoma
Comparison of Concentration of Vasopressin During Robot-assisted Laparoscopic Myomectomy
The purpose of this study is to compare the effect of the concentration of vasopressin, which is used as a method for reducing blood loss in robot-assisted laparoscopic myomectomy.
- Trial name
- VALENTINE (NCT04874246)
- Testing
- Vasopressin
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Seoul National University Hospital
Postpartum Hemorrhage, Uterine Atony
Exteriorization Versus In Situ Hysterotomy Repair During Cesarean: Effects on Uterine Tone
During standard cesarean deliveries, there are two ways that obstetricians repair the incision on the uterus (hysterotomy after delivery of the baby.
- Conditions
- Postpartum Hemorrhage, Uterine Atony, Uterine Atony With Hemorrhage, Cesarean Section
- Trial name
- NCT07606846
- Testing
- Test Intervention: In Situ Repair, Comparator Intervention: Exteriorization
- Volunteers
- 60 people
- Sponsor
- Stanford University
Menorrhagia
Pattern of Menorrhagic Female Attending the Hematology Unit in Assuit University Children Hospital
To Evaluate Causes of Menorrhagia in Adolescent FemalesSpecially Hematological causes to help in management of abnormal uterine bleeding.
- Trial name
- Menorrhagia (NCT06660459)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Dysmenorrhea, Metrorrhagia
Cooperative Adenomyosis Network
To set up a Cooperative Network by enrolling 5000 patients with Adenomyosis(AM) from multiple centers.Based on the Network platform and Database,the investigators try to explore the diagnostic strategies for AM and carry out…
- Conditions
- Dysmenorrhea, Metrorrhagia, Infertility, Female, Pathology
- Trial name
- CAN (NCT03230994)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Peking Union Medical College Hospital
Menorrhagia, Fibroid
Hysteroscopic Monopolar and Bipolar Resection
The aim of the study is to evaluate bipolar equipment versus monopolar, and to see if there is any differences between the two types of bipolar equipment espescially regading both safety and effect.
- Conditions
- Menorrhagia, Fibroid, Polyps
- Trial name
- NCT00323999
- Testing
- Hysteroscopic resection of fibroids, polyps and endometrium.
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Dysfunctional Uterine Bleeding
Study of a Progestin to Prevent Bleeding Associated With Initiation of Medical Menopause With GnRH Agonist
In this study, the investigators would like to see if giving medroxyprogesterone acetate for 3 weeks after Leuprolide acetate injection will help to decrease this amount of bleeding, decrease the amount of nausea, bloating and…
- Trial name
- NCT01776203
- Testing
- Medroxyprogesterone 17-Acetate
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Kaiser Permanente
Placenta Accreta, Blood Pressure
CNAP vs IABP in Pregnant Women With Placenta Accreta
The objective of this study is to investigate a technique to monitor blood pressure in women undergoing cesarean delivery with suspected placenta accreta spectrum.
- Conditions
- Placenta Accreta, Blood Pressure, Hemorrhage, Hemorrhage, Postpartum
- Trial name
- NCT04671680
- Testing
- LiDCO CNAP Monitoring Equipment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Postpartum Hemorrhage
Prevention of Postpartum Haemorrhage With Sublingual Misoprostol or Oxytocin
Sublingual misoprostol produces rapid peak concentration and is more effective than oral misoprostol for prevention of excessive postpartum bleeding.
- Trial name
- NCT01373359
- Testing
- Misoprostol, Oxytocin
- Where
- India
- Volunteers
- 652 people
- Sponsor
- Jawaharlal Nehru Medical College
Pregnancy, Hemorrhage
Post-Cesarean Wound Drainage is Not Necessary in Women at Increased Risk of Hemorrhage
Randomized controlled trial assessing the benefit of cesarean wound drainage in pregnant women at increased risk of hemorrhage. The pregnant women at increased risk of hemorrhage were randomised in two groups.
- Trial name
- NCT00779727
- Testing
- Placement of drainages
- Where
- Switzerland
- Sponsor
- University of Zurich
Menorrhagia, Abnormal Uterine Bleeding
Efficacy of Calcium Dobesilate Versus Tranexamic Acid for Treating Heavy Menstrual Bleeding
The goal of this clinical trial is to determine if calcium dobesilate is an effective alternative to tranexamic acid for treating menorrhagia in women aged 18 to 39 years.
- Trial name
- NCT06763094
- Testing
- Calcium dobesilate (Doxium), Tranexamic Acid
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Uterine Fibroids
Post Market TRUST Study
This Post Market study is being conducted to compare the direct and indirect cost of three approaches (GFA, myomectomy, and uterine artery embolization) for the treatment of symptomatic uterine fibroids.
- Trial name
- TRUST (NCT01563783)
- Testing
- Global Fibroid Ablation (GFA), Abdominal or Laparoscopic Myomectomy, Uterine Artery Embolization (UAE)
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Acessa Health, Inc.
Postpartum Hemorrhage (Primary)
Effect of Extracellular Calcium on Carbetocin Mediated Contractility in Human Myometrium
Postpartum hemorrhage (PPH) continues to be an increasing problem globally. Uterotonics play an essential role in the pharmacological management of uterine atony.
- Trial name
- NCT06930391
- Testing
- Oxytocin, Carbetocin, Calcium
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Midwifery Student
The Effect of Gamification-Based Instructional Design Developed
Turkish) Abstract: Purpose: Considering the importance of postpartum hemorrhage management in reducing preventable maternal deaths and the key role midwives play in providing this care, it is important to increase the knowledge…
- Trial name
- PPH-GamEd (NCT07207590)
- Testing
- web-based gamification application, control group: traditional classroom learning techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Immune Thrombocytopenia, Pregnancy Related
IVIg Plus Low Dose rhTPO for ITP in Pregnancy
Randomized, open-label, multicenter study to investigate the efficacy and safety of IVIg plus low-dose recombinant thrombopoietin in pregnant patients with corticosteroid or IVIg monotherapy-resistant ITP.
- Trial name
- NCT05634824
- Testing
- intravenous immunoglobulin plus low dose recombinant human thrombopoietin (rhTPO), intravenous immunoglobulin
- Volunteers
- 50 people
- Sponsor
- Peking University People's Hospital
Kidney Calculi, Nephrolithiasis
Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones.
- Trial name
- NCT07749807
- Testing
- Nebulized Glubran 2-Assisted Tubeless PCNL, Conventional PCNL With Nephrostomy Tube
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Post Partum Haemorrhage
Compare Efficacy of Oxytocin Administrations on Postpartum Uterine Contractility
This is a Phase I open-label, parallel-group clinical study in healthy term pregnant females undergoing a caesarean section. Two administrations of oxytocin will be tested, after which uterine contractility will be assessed.
- Trial name
- NCT02908126
- Testing
- Oxytocin
- Where
- Sweden
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Oxytone Bioscience BV
Acute Kidney Injury, Ischemia Reperfusion Injury
Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Liver Transplant Patients
The purpose of this study is to find out if a drug called valproic acid (VPA) will protect organs (like the kidneys) from harmful effects caused by the temporary drop and then rise of blood flow and oxygen (called ischemia…
- Trial name
- NCT04531592
- Testing
- Valproic acid, Isotonic saline solution
- Where
- 4 sites in United States
- Sponsor
- Westat
Postpartum Hemorrhage
Prevention of Postpartum Hemorrhage With Tranexamic Acid
Postpartum hemorrhage is a significant contributor to maternal morbidity and mortality and is worldwide. TXA has recently been proven to reduce mortality when given to women in setting of diagnosed PPH.
- Trial name
- NCT03287336
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- George Washington University
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