Clinical trials: Pregnancy Hemorrhage
Total Laparoscopic Hysterectomy, Laparoscopic Supracervical Hysterectomy
Long Term Outcomes Following Total Laparoscopic Hysterectomy and Laparoscopic Supracervical Hysterectomy
Objective: To compare the occurrence and intensity of pelvic pain as well as patient satisfaction and quality of life after total laparoscopic and laparoscopic supracervical hysterectomy. Design: Prospective randomised trial.
- Conditions
- Total Laparoscopic Hysterectomy, Laparoscopic Supracervical Hysterectomy, Fibromas, Abnormal Uterine Bleeding
- Trial name
- NCT01289314
- Testing
- TLH, Laparoscopic supracervical hysterectomy
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- Oslo University Hospital
Postpartum Hemorrhage
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Vaginal Delivery
Postpartum hemorrhage is one of the leading causes of maternal morbidity following childbirth. Even when excessive bleeding is not clinically recognized, some women experience a significant decrease in hemoglobin levels after…
- Trial name
- NCT07714902
- Testing
- calcium gluconate
- Where
- Israel
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Immune Thrombocytopenia
Prednisone Plus IVIg vs. Prednisone for ITP During Pregnancy
This is a prospective, randomized, open-label, multicenter clinical trial study to compare the efficacy and safety of prednisone plus IVIg to prednisone monotherapy in the treatment of immune thrombocytopenia (ITP) in pregnancy.
- Trial name
- IVIg (NCT06577909)
- Testing
- Prednisone, IVIg
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Placenta Accreta, Post Partum Hemorrhage
Conservative Management of Placenta Accreta Spectrum
The resective-constructive surgery, detailed in prior research by Palacios-Jaraquemada JM, involves excising the placenta and its attachment on the myometrium, with modifications including the systematic use of a double JJ probe…
- Conditions
- Placenta Accreta, Post Partum Hemorrhage, Blood Loss Massive
- Trial name
- NCT06253832
- Testing
- conservative surgery for placenta accreta spectrum, hysterectomy
- Where
- Tunisia
- Volunteers
- 36 people
- Sponsor
- Tunis University
Myomectomy; Surgical Blood Loss
Rectal Misoprostol as a Hemostatic Agent During Abdominal Myomectomy
Purpose is to identify if misoprostol in addition to local vasopressin decreases blood loss when compared to vasopressin alone, which is our current practice at this time.
- Trial name
- NCT03064568
- Testing
- Misoprostol 200Mcg Tab
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Postpartum Hemorrhage
Pharmacokinetics of Oxytocin at Cesarean Delivery
The primary objective is to obtain data to inform the design of a population pharmacokinetic study of oxytocin after administration at CD as per standard institutional practice.
- Trial name
- Peacocks (NCT03898882)
- Testing
- oxytocin, Shore durometer
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Dysfunctional Uterine Bleeding
COMPARISON OF A NEW FORMULATION OF GOSERELIN (Pepti 3.6 mg) to Zoladex® 3.6 mg
The comparator drug (Zoladex 3.6 mg) is approved for use as a thinning agent for the endometrium prior to endometrial ablation. The dosing recommendation is one or two depots with each depot given four weeks apart.
- Trial name
- NCT04428684
- Testing
- Pepti 3.6 mg
- Where
- 5 sites in Ukraine
- Volunteers
- 80 people
- Sponsor
- Peptigroupe Inc.
Blood Loss
Maternal-fetal Outcomes of Genital Blood Loss Beyond 18 Weeks of Pregnancy
The primary objective is to assess in terms of frequency the adverse outcomes (premature birth, maternal-fetal haemorrhage, maternal fetal-neonatal death) of pregnancies of women attending the obstetric-gynaecological emergency…
- Trial name
- PEG18 (NCT06802874)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Quality of Life, Stroke, Acute
Cerebrovascular Disease: Quality of Life (CODE: QoL)
The goal of this observational study is to learn about quality of life, stress and caregiver burden in patients with stroke and their caregivers.
- Conditions
- Quality of Life, Stroke, Acute, Sexual Behavior, Stress
- Trial name
- CODE:QoL (NCT06443268)
- Testing
- questionnaire, hair samples, blood samples, clinical exam
- Where
- Switzerland
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Intraventricular Hemorrhage, Sepsis
Placental Transfusion Project for Preterm Infants
The American College of Obstetrics and Gynecology, American Academy of Pediatrics and the World Health Organization have recently published recommendations related to placental transfusions in preterm infants.
- Conditions
- Intraventricular Hemorrhage, Sepsis, Necrotizing Enterocolitis
- Trial name
- NCT02400697
- Testing
- <30 wks gestation or 1500 grams
- Where
- United States
- Volunteers
- 2,856 people
- Sponsor
- Indiana University
Postpartum Hemorrhage
IV vs IM Oxytocin in the Third Stage of Labor for Prevention of Postpartum Hemorrhage
The study will evaluate whether prophylactic oxytocin administered in the third stage of labor via IV infusion results in a lower mean blood loss compared to IM injection.
- Trial name
- NCT01608958
- Testing
- Oxytocin
- Where
- 3 sites in Ecuador, Turkey (Türkiye) and 1 more
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Myoma, Uterine Bleeding, Dysfunctional
Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy
A prospective observational study on italian women undergoing ulipristal acetate (uPa) therapy for symptomatic myomas and its impact on symptomatology and moreover on myomas architecture.
- Conditions
- Myoma, Uterine Bleeding, Dysfunctional, Uterine Bleeding Heavy, Dysmenorrhea
- Trial name
- NCT03972917
- Testing
- Transvaginal ultrasonographic examination
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- University of Campania Luigi Vanvitelli
Placenta Previa
Effect of a Cervical Pessary on the Rate of Bleeding in Placenta Praevia
This study evaluates whether use of a cervical pessary can reduce vaginal bleeding and prolong pregnancy in women with placenta previa or a low-lying placenta.
- Trial name
- NCT07667777
- Testing
- Cervical pessary
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- Asklepios proresearch
Ovarian Cancer, Perioperative Blood Loss
Comparison of Single-Dose Tranexamic Acid Vs. Placebo in Ovarian Cancer Surgery
This study evaluated the effectiveness of a single dose of tranexamic acid compared to a placebo in reducing blood loss and the need for blood transfusions in women undergoing surgery for ovarian cancer.
- Conditions
- Ovarian Cancer, Perioperative Blood Loss, Blood Transfusion Events
- Trial name
- NCT06879353
- Testing
- Tranexamic Acid (TXA)
- Where
- Pakistan
- Volunteers
- 372 people
- Sponsor
- Sheikh Zayed Medical College
Uterine Fibroids, Heavy Menstrual Bleeding
Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women
This study seeks to evaluate the efficacy, safety and tolerability of elagolix alone and in combination with estradiol/norethindrone acetate for the management of heavy menstrual bleeding associated with uterine fibroids in…
- Trial name
- NCT02654054
- Testing
- Elagolix, Estradiol/Norethindrone Acetate
- Where
- 96 sites in United States, Canada and 1 more
- Volunteers
- 413 people
- Sponsor
- AbbVie
Prematurity, Bronchopulmonary Dysplasia
Inhaled Nitric Oxide and Neuroprotection in Premature Infants
The purpose of this study is to determine whether inhaled nitric oxide improves the neurological outcome for premature infants.
- Conditions
- Prematurity, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Periventricular Leukomalacia
- Trial name
- NOVA2 (NCT00515281)
- Testing
- inhaled nitric oxide, oxygen
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- University of Chicago
Postpartum Hemorrhage \(PPH\)
Comparison of the Effect of Carbetocin Versus Oxytocin in the Prevention of Postpartum Hemorrhage After Emergency Caesarean Section in Antenatal Low-risk Patients
This study will be conducted to compare the effects of pabal and oxytocin administered to prevent postpartum hemorrhage in patients who were followed in the delivery room due to vaginal labor but underwent cesarean section due to…
- Trial name
- EMERGE-CS (NCT07380529)
- Testing
- Carbetocin, Oxytocin
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Endometrial Cancer, Atypical Hyperplasia
OSCAR ENDO One Stop Assessment of Risk for Endometrial Hyperplasia and Cancer
It is to be achieved that in postmenopausal women through the combination of Hysteroscopy and intraoperative rapid section a positive predictive value (PPV) regarding the objective illness like endometrial cancer or adenomatous…
- Trial name
- NCT01961102
- Testing
- hysteroscopy/curettage in case of suspicious aspect will be done a rapid section
- Where
- Austria
- Volunteers
- 300 people
- Sponsor
- Krankenhaus Barmherzige Schwestern Linz
Anti-Glomerular Basement Membrane Disease, Anti-Glomerular Basement Membrane Antibody Disease
A Study With Imlifidase in Anti-GBM Disease
An open-label, controlled, randomised, multi-centre Phase 3 trial evaluating renal function in patients with severe anti-GBM disease comparing imlifidase and standard of care (SoC) with SoC alone.
- Conditions
- Anti-Glomerular Basement Membrane Disease, Anti-Glomerular Basement Membrane Antibody Disease, Goodpasture Syndrome, Good Pasture Syndrome
- Trial name
- GOOD-IDES-02 (NCT05679401)
- Testing
- Imlifidase, Plasma exchange (PLEX), Cyclophosphamide (CYC)
- Where
- 48 sites in United States, Austria and 11 more
- Volunteers
- 50 people
- Sponsor
- Hansa Biopharma AB
Postpartum Hemorrhage, Pain
Do Elastic Abdominal Binders Reduce Post Operative Pain and Blood Loss?
This is a pilot study investigating the use of abdominal binders after cesarean sections. The researchers are testing whether elastic abdominal binders improve postoperative pain control and reduce postoperative blood loss.
- Trial name
- NCT01786330
- Testing
- Procare abdominal binder, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zachary Kuhlmann, DO
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