Clinical trials: Pregnancy Outcomes
Perinatal Outcomes, Social Determinants of Health (SDOH)
Rhode Island Community-based Maternal Support Services
The purpose of this project is to improve perinatal health outcomes in Rhode Island by bringing together the hospital, community health workers (CHWs), doulas, and community-based organizations to build a service delivery model…
- Conditions
- Perinatal Outcomes, Social Determinants of Health (SDOH), Health Disparity, Minority and Vulnerable Populations, Pregnancy
- Trial name
- RICOMSS (NCT07446374)
- Testing
- Perinatal health screening, Support services
- Where
- 7 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Pregnancy Outcome
NIH Intramural Research Program s Pregnancy Registry Protocol for Subjects and Their Partners
Background: In 2018, the NIH intramural research program had almost 23,000 people taking part in active clinical research studies. Half of those people were female. More than a third were of child-bearing age.
- Trial name
- NCT04977466
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Hypertensive Disorder of Pregnancy, Premature Preterm Rupture of Membranes
HOME: Home Monitoring of High-risk Pregnancies
High-risk pregnancies often require long-term hospitalization or outpatient maternal and/or fetal monitoring, placing a burden on patients, hospital resources and society.
- Conditions
- Hypertensive Disorder of Pregnancy, Premature Preterm Rupture of Membranes, Preeclampsia, High Risk Pregnancy
- Trial name
- NCT05763069
- Testing
- Home surveillance of pregnancies at risk
- Where
- Norway
- Volunteers
- 250 people
- Sponsor
- Oslo University Hospital
Pregnancy Outcome Trends in Low-resource Geographic Areas
Maternal Newborn Health Registry
The primary purpose of this population-based study is to quantify and understand the trends in pregnancy outcomes in defined low-resource geographic areas over time, in order to provide population-based data on stillbirths…
- Trial name
- MNH (NCT01073475)
- Testing
- There is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
- Where
- 15 sites in United States, Bangladesh and 5 more
- Volunteers
- 950,000 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Placental Insufficiency Hypertensive Disorders of Pregnancy Diabetes Mellitus in Pregnancy Thrombophilia in Pregnancy Adverse Perinatal Outcomes
Fetus Programming and Long Active Outcomes, Interaction Between Mother, Placenta and Fetus in Perinatal and Methabolic Disbalansces-focusing Diabetic Pregnancies
The placenta is a temporary but essential organ that develops during pregnancy and supports the growth and survival of the fetus.
- Trial name
- NCT07337759
- Testing
- No intervention (observational study)
- Where
- Serbia
- Volunteers
- 440 people
- Sponsor
- University of Belgrade
Food Insecurity, Pregnancy
An Agricultural Livelihood Intervention for Pregnant Women
Scarcity of food is a leading cause of sickness and death in mothers and their newborns in sub-Saharan Africa. Use of locally acceptable agricultural interventions including provision of agricultural supplies, training and having…
- Conditions
- Food Insecurity, Pregnancy, Birth Outcomes, Livelihood Interventions
- Trial name
- NCT07043647
- Where
- Kenya
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Perinatal and Neonatal Outcomes in Pregnancies With Type 2 Diabetes Mellitus (T2DM)
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
This feasibility pilot study aims to gather data that can guide the design of a larger, more comprehensive trial to establish the effects of myo-inositol supplementation on supporting healthy outcomes in pregnancies complicated…
- Trial name
- AMulet (NCT07241221)
- Testing
- Myo-inositol and folic acid supplement, Folic acid supplement
- Where
- Singapore
- Volunteers
- 182 people
- Sponsor
- National University Hospital, Singapore
Low Birth Weight Baby, Small for Gestational Age (SGA)
Biological Impacts of Rising Temperatures on Maternal, Fetal, and Newborn Health: A Cohort Study (BIRTH Cohort)
The goal of this study is to learn how being exposed to high environmental temperatures during pregnancy affects the health of pregnant women and their babies.
- Conditions
- Low Birth Weight Baby, Small for Gestational Age (SGA), Preterm Birth, Pregnancy Complications
- Trial name
- BIRTH (NCT06957769)
- Testing
- heat stress
- Where
- 3 sites in Pakistan
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Health Problems in Pregnancy, Pregnancy Outcomes
Peking University Birth Cohort in Weifang (PKUBC-WF)
The PKUBC-WF is a prospective cohort study carried out in Weifang city of Shandong, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal and…
- Conditions
- Health Problems in Pregnancy, Pregnancy Outcomes, Gestational Diabetes, Gestational Hypertension
- Trial name
- NCT06234332
- Testing
- No Interventions
- Where
- China
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Peking University
Sarcopenia, Gestational Diabetes Mellitus (GDM)
Sarcopenia in Gestational Diabetes
Sarcopenia is a syndrome characterized by loss of skeletal muscle mass and strength, and physical performance deterioration. Prevalence of sarcopenia in elderly people is remarkably high (prevalence of about 25% in 60+ years…
- Conditions
- Sarcopenia, Gestational Diabetes Mellitus (GDM), Pregnancy Complications, Adverse Maternal and Neonatal Outcomes
- Trial name
- SiGnal-D (NCT06876090)
- Testing
- Sarcopenia tests (for muscle mass, muscle function, physical performance), Oral Glucose Tolerance Test, Montreal Cognitive Assessment
- Where
- 3 sites in Austria, Italy
- Volunteers
- 200 people
- Sponsor
- Istituto di Neuroscienze Consiglio Nazionale delle Ricerche
Newborn Health, Multiple Micronutrient Deficiencies During Pregnancy
The MOM-CARE Trial : Evaluating Antenatal and Postnatal MMSPlus for Improved Infant Birth and Growth Outcomes
This clinical trial aims to learn if MMS Plus improves infant health compared to standard MMS during pregnancy and the postnatal period in women living in peri-urban areas of Karachi, Pakistan.
- Conditions
- Newborn Health, Multiple Micronutrient Deficiencies During Pregnancy, Nutrition During Pregnancy, Adaptive Trial
- Trial name
- MOM-CARE (NCT07029282)
- Testing
- MMS, MMS Plus, IFA
- Where
- Pakistan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Fetal Growth Restriction, Perinatal Outcome
Relationship of DV Doppler Parameters to Perinatal Outcomes in IUGR vs Non-IUGR
This observational study investigates whether blood flow in the ductus venosus, a small fetal vein measured by Doppler ultrasound, is related to pregnancy outcomes.
- Conditions
- Fetal Growth Restriction, Perinatal Outcome, Pregnancy, High Risk
- Trial name
- DV-FGR (NCT07190157)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Outcome, Adverse Birth, Childbirth Experience
Effects and Childbirth Experience Between Zhang and WHO Partograph
This study compared the labour outcomes and childbirth experience between Zhang and WHO partograph.
- Trial name
- NCT07121491
- Where
- Malaysia
- Volunteers
- 713 people
- Sponsor
- National University of Malaysia
Anxiety, Pregnancy Outcomes
Effect of Breathing Exercises on Embryo Transfer Outcomes
Breathing exercises are being used in many different clinical issues in the area of medicine. Also in gynecological practice, especially during labor, breathing exercises are encouraged by health professionals to aid the…
- Trial name
- BreathIVF (NCT07109544)
- Testing
- Breathing Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eurofertil IVF Health Center
Antenatal Care, Pregnancy Complications
A Culturally Adapted Digital Intervention to Promote Maternal Care Utilization Using Multifaceted Approaches
Maternal healthcare utilization is crucial for reducing maternal mortality, yet remains low in many underserved regions. The CALCIUM intervention, a culturally tailored, digital platform-integrated intervention, was developed to…
- Conditions
- Antenatal Care, Pregnancy Complications, Pregnancy Outcomes
- Trial name
- NCT07091188
- Testing
- Health education, capacity building and economic incentives
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Jiayao Xu
Pregnancy, Neurodevelopment
Maternal Risk, Fetal-Neonatal Brain Connectivity, and Early Neurodevelopment: A Longitudinal Observational Study
This study aims to understand how a pregnant woman's health, lifestyle, and psychological state-especially when associated with known risk factors-might influence the developing brain of her baby, both before and after birth.
- Conditions
- Pregnancy, Neurodevelopment, Brain Connectivity, Neurodevelopment Outcome
- Trial name
- MaMRI-NeUCogI (NCT07059286)
- Testing
- Maternal Frailty Inventory (MaFra) Questionnaire, Fetal Resting-State Functional MRI, Maternal Emotional Reactivity
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- IRCCS San Raffaele
Birth Outcome, Adverse
Knowledge, Attitudes, and Practices of Operative Vaginal Birth Among Obstetric Providers in Egypt
The goal of this observational study is to evaluate the knowledge, attitudes, and practices of operative vaginal birth among obstetric providers in Egypt.
- Trial name
- NCT06502119
- Testing
- Designed Questionnaire
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Early Pregnancy, Fasting Plasma Glucose
Effectiveness of a Lifestyle Intervention for Pregnant Women With Abnormal Glucose Metabolism in Early Pregnancy: EAGM Trial
This is a multicentre, parallel-group, open-label, pragmatic, randomised-control trial of early lifestyle intervention versus routine prenatal care by random allocation (1:1) in women with early abnormal glucose metabolism (EAGM)…
- Conditions
- Early Pregnancy, Fasting Plasma Glucose, Hemoglobin A1c Protein, Human, Lifestyle Intervention
- Trial name
- EAGM (NCT06767722)
- Testing
- Lifestyle intervention and self-monitoring of blood glucose
- Where
- China
- Volunteers
- 3,430 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Pregnancy, Mental Health
Life vs. Digital Music Interventions Performed by Professionals Throughout Pregnancy to Increase Mental Health for Mothers and Their Offspring
This prospective study was preceded by an extensive feasibility study between 2021-2024. Thereby, pregnant women were exposed to live music and a variety of creative workshops such as vibration, modelling, creative writing…
- Conditions
- Pregnancy, Mental Health, Maternal and Child Health Outcomes
- Trial name
- MusicMums (NCT07003048)
- Testing
- Singing, dancing in small groups and active listening to live music at the Berlin Philharmony building
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Clara Angela Foundation
Pregnancy Outcome
Foley Balloon Study for Cervical Ripening - Cost Comparison Between Outpatient and Inpatient Cervical Ripening
The objective of this study is to determine the impact of outpatient cervical ripening with transcervical balloon placement for induction of labor at term on the length and cost of inpatient hospitalization when compared to…
- Trial name
- Balloon (NCT05506631)
- Testing
- Outpatient Foley balloon placement, Inpatient Foley Balloon placement
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Lehigh Valley Hospital