Clinical trials: Pregnancy Outcomes
Cervical Incompetence
Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC)
The investigator aimed to compare the effect of anesthesia on overall postoperative outcomes including post-operative pain score and the fetal well-being (heart rate) in patients undergoing transabdominal cervico isthmic…
- Trial name
- NCT03636048
- Testing
- Bupivacaine Hcl 0.5% Inj, Propofol 10 milligram/ML
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Pre-Eclampsia, Early Onset Preeclampsia
Early Onset Preeclampsia and Nectin-4
Early-onset Preeclampsia (PE) is a pregnancy disorder which may present with adverse pregnancy outcomes. Nectin-4 is an adhesion molecule mainly expressed in placenta.
- Conditions
- Pre-Eclampsia, Early Onset Preeclampsia, Oxidative Stress, Immunologic Diseases in Pregnancy
- Trial name
- NCT05098691
- Testing
- serum marker levels
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Hatice Akkaya
Preeclampsia
Fetal Renal Artery Doppler in Patients With Preeclampsia
Preeclampsia is a major devastating disorder affects 2:10% of pregnancies worldwide. preeclampsia may be associated with placental insufficiency which may cause fetal blood redistribution to essential organs like brain, heart…
- Trial name
- NCT06395974
- Testing
- fetal ultrasound
- Where
- Egypt
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cancer of Cervix
Para-Aortic Lymph Nodal Staging & Evaluation of Treatment Outcome by 18F FDG-PET in Advanced Cancer Cervix
18F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Imaging has been extensively used in the evaluation of various malignancies and is rapidly being recognized as a mandatory investigations.
- Trial name
- NCT00193752
- Testing
- PET IMAGING
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Tata Memorial Hospital
Urinary Bladder, Overactive, Urodynamics
Evaluation the Efficacy Between Botox Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity
To investigates the effects of botulinum toxin type A bladder injection compared to combined pharmacotherapy with Mirabegron and Solifenacin.
- Conditions
- Urinary Bladder, Overactive, Urodynamics, Effect of Drug
- Trial name
- NCT05968885
- Testing
- Intradetrusor Botox® (onabotulinumtoxinA) injection, Combine Mirabegron and Solifenacin.
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Mackay Memorial Hospital
Hypertension Induced by Pregnancy, Pre-Eclampsia
Placental Growth and Adverse Pregnancy Outcomes
The purpose of this study to determine if measurement of maternal serum biomarkers and evaluation of the placenta by ultrasound can improve prediction of adverse pregnancy outcomes.
- Conditions
- Hypertension Induced by Pregnancy, Pre-Eclampsia, IUGR
- Trial name
- NCT01669525
- Where
- United States
- Volunteers
- 1,043 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep Disorder
A Cohort Study on Sleep Disorders During Pregnancy
The goal of this observational study is to: 1) determine the prevalence of sleep disorders in pregnancy and the early postpartum; 2) identify factors associated with sleep disturbance during pregnancy and the early postpartum; 3)…
- Trial name
- NCT05765149
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Adverse Pregnancy Outcomes, Cardiovascular Diseases
A Randomized Trial to Reduce Blood Pressure at One Year Postpartum After Preeclampsia
GESTA-COR is a prospective, randomized clinical trial designed to evaluate whether an early, personalized cardiovascular prevention strategy can achieve a clinically meaningful 6 mmHg reduction in systolic blood pressure at one…
- Trial name
- GESTA-COR (NCT06798649)
- Testing
- The intervention in the GESTACOR study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs).
- Volunteers
- 150 people
- Sponsor
- Maternal-Infantil Vall d´Hebron Hospital
Hypertensive Disorder of Pregnancy, Sleep Apnea, Obstructive
Positive Airway Pressure Treatment of Obstructive Sleep-disordered Breathing in Hypertensive Disorders of Pregnancy
The purpose of this study is to conduct a pilot randomized, controlled trial to evaluate the feasibility and obtain pilot outcome data for a subsequent definitive trial evaluating the effects of postitive airway pressure (PAP)…
- Trial name
- NCT03309826
- Testing
- Positive Airway Pressure, Nasal Dilator Strip
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Dr John Kimoff
Gestational Diabetes Mellitus in Pregnancy, Pregnancy, High Risk
Early Detection of Gestational Diabetes Mellitus in Pregnancy
The purpose of this study is to develop an implementation protocol and test the feasibility and acceptability of a first trimester screening protocol for the early detection of gestational diabetes mellitus (GDM).
- Trial name
- NCT05388643
- Testing
- Enhanced First Trimester GDM Screening, Routine Gestational Diabetes Screening
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Massachusetts, Worcester
Prenatal Education, Pregnancy Related
Effect of Hypnobirthing Training on Fear, Pain, Satisfaction and, Birth Outcomes
Background and Purpose: Hypnobirthing is childbirth education model. This model aims for women to have a painless, calm and more comfortable birth.
- Conditions
- Prenatal Education, Pregnancy Related, Labor Pain
- Trial name
- NCT04838340
- Testing
- Standart care, Hypnobirthig training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Kidney Stones, Renal Calculi
Database and Registry for Renal Diverticulum
Historically, percutaneous treatment of stone-bearing caliceal diverticula has resulted in the best success rates when examining factors such as symptom relief and stone-free rates (Jones, et al, 1991).
- Conditions
- Kidney Stones, Renal Calculi, Tic
- Trial name
- NCT00169715
- Testing
- Percutaneous Caliceal Diverticuli
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Indiana Kidney Stone Institute
Being Diagnosed With Primary Infertility, Having Had an Embryo Transfer for the First Time
Effects of Virtual Reality Glasses and Meditation Music on Anxiety, Pain, Vital Signs, Satisfaction and Pregnancy Outcomes in Embryo Transfer Procedure
The aim of this study is to determine the effects of virtual reality glasses (VRG) and meditation music on anxiety, pain, vital signs, satisfaction and pregnancy outcomes during the embryo transfer (ET) procedure.
- Trial name
- NCT06802692
- Testing
- VR glasses and meditation music group, Meditation music group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Nuh Naci Yazgan University
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Gestational Diabetes Mellitus, Intrauterine Hyperglycemia
Wenzhou Gestational Diabetes Cohort
The Wenzhou Gestational Diabetes Cohort (WGDC) is a prospective cohort study among women with gestational diabetes mellitus (GDM) during pregnancy and their offspring living in Wenzhou, China.
- Conditions
- Gestational Diabetes Mellitus, Intrauterine Hyperglycemia, Birth Outcome, Adverse, Nutrition, Healthy
- Trial name
- WGDC (NCT05794152)
- Testing
- Standardized breakfast, Standardized snack, Standardized lunch
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Westlake University
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
Cervix Cancer
Impact of Erythropoietin Administration During Definitive Cervix Cancer Radiotherapy on Treatment Outcome
The purpose of this study is to determine whether an increase of blood haemoglobin levels through the substitution of erythropoietin during radiotherapy treatment of cervix cancer patients results in improvement for disease…
- Trial name
- NCT00348738
- Testing
- Erythropoietin
- Where
- 4 sites in Austria
- Volunteers
- 300 people
- Sponsor
- Medical University of Vienna
Poor Ovarian Response
Ovarian PRP Injection in Women With POR
Patients with poor ovarian response (POR）is considered one of most challenging tasks in artificial reproductive treatment (ART).
- Trial name
- NCT05601193
- Testing
- autologous platelet-rich plasma
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Chronic Kidney Disease, Frailty
Effect of Synchronized Transcutaneous Electrical Diaphragm Stimulation Using Surged Faradic Current Combined With Inspiratory Muscle Training on Diaphragm Function and Clinical Outcomes in Patients With COPD
Chronic kidney disease (CKD) is a progressive condition that can be associated with reduced physical capacity, muscle weakness, fatigue, respiratory impairment and frailty.
- Trial name
- COPD TEDS (NCT07803900)
- Testing
- Transcutaneous electrical diaphragm stimulation (TEDS), Inspiratory muscle training (IMT)
- Where
- India
- Volunteers
- 42 people
- Sponsor
- Maharashtra University of Health Sciences
Endometriosis, Infertility
Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF
This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the…
- Trial name
- IntegrinIVF (NCT00621179)
- Testing
- Leuprolide acetate in depot suspension, No intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Colorado Center for Reproductive Medicine