Clinical trials: Pregnancy Related Complications
Preeclampsia, Small for Gestational Age at Delivery
Early Vascular Adjustments to Prevent Preeclampsia
Women destined to develop gestational hypertensive complications often exhibit deviant hemodynamic adaptation patterns before overt clinical disease.
- Conditions
- Preeclampsia, Small for Gestational Age at Delivery, HELLP Syndrome
- Trial name
- NCT04216706
- Testing
- tailored pharmaceutical treatment
- Where
- Netherlands
- Volunteers
- 314 people
- Sponsor
- Maastricht University Medical Center
Multiple Sclerosis
Identification of Factors Related to UI in Patients With MS and EMG Assessment of PFM Activity
The study aimed to explore the link between urinary incontinence (UI) severity in patients with multiple sclerosis (PwMS), electromyography (EMG) findings, and other relevant factors.
- Trial name
- NCT07236684
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Artvin Coruh University
Hypoxia, Autophagy
Hypoxia-induced Autophagy in the Pathogenesis of MAP
To investigate the role of HIF 1α and LC3B in the pathogenesis of MAP, to evaluate the role of MMP-9 in the antenatal prediction of MAP, and to compare the expression of HIF1α, LC3B, and level MMP-9 between patients of placenta…
- Conditions
- Hypoxia, Autophagy, Placenta, Morbidly Adherent Placenta
- Trial name
- NCT05817448
- Testing
- HIF 1α and LC3B expression and MMP-9 level
- Volunteers
- 80 people
- Sponsor
- Assiut University
End Stage Kidney Disease
Blood Volume Analysis and Related Outcomes in Hemodialysis
An understanding of fluid changes that occur during hemodialysis (HD) with ultrafiltration (UF) is essential for determining the efficacy of HD, as well as for reducing complications related to hypovolemia or, conversely, chronic…
- Trial name
- NCT01679249
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA New York Harbor Healthcare System
Mild Pre-eclampsia, Severe Preeclampsia
İs There a Relationship Between Severity of Preeclampsia and Maternal Heavy Metal Levels?
The purpose of this study, to investigate whether severity of preeclampsia is associated with altered levels of heavy metals (Cd, Hg, arsenic and Pb) in maternal blood, fetal blood, and maternal hair.
- Trial name
- NCT01906567
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Stress Urinary Incontinence, Pregnancy Related
Pessary Use for Stress Urinary Incontinence in Pregnancy
When women are pregnant they are more likely to leak urine which can severely affect their quality of life. This problem could be fixed by using a pessary.
- Trial name
- NCT04590092
- Testing
- Cooper Surgical Ring Pessary with Incontinence Knob
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Treatment Related Cancer, Ovarian Cancer
SY001 Targets Mesothelin in a Single-arm, Dose-increasing Setting in Subjects With Advanced Solid Tumors
Single-arm, dose-increasing setting study of CAR macrophages in Mesothelin overexpressing solid tumors.
- Trial name
- NCT06562647
- Testing
- SY001
- Where
- 2 sites in China
- Volunteers
- 2 people
- Sponsor
- Cell Origin Biotech (Hangzhou) Co., Ltd.
DSD, 46,XY, DSD, Ovotesticular
Gonadal Tissue Cryopreservation for Fertility Preservation in Children With a Disorder of Sex Development
The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer).
- Conditions
- DSD, 46,XY, DSD, Ovotesticular, DSD, Sex Chromosome, Disorders of Sex Development
- Trial name
- DSD (NCT06692049)
- Testing
- Gonadectomy
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Erin Rowell
Bladder Cancer, Cervical Cancer
Motivational Counseling in Preventing Smoking Relapse After Pregnancy in Pregnant Women Who Quit Smoking During Pregnancy
RATIONALE: Motivational counseling may help prevent pregnant women from smoking again after pregnancy. PURPOSE: This randomized clinical trial is studying three different types of counseling to see how well they work in…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00310115
- Testing
- Smoking Prevention Usual Care, Counseling Intervention
- Where
- United States
- Volunteers
- 469 people
- Sponsor
- M.D. Anderson Cancer Center
Autism Spectrum Disorder, Cerebral Palsy
READYorNot[TM] Brain-Based Disabilities Trial
The purpose of this study is to find out if there is a benefit to using the MyREADY Transition[TM] BBD App for brain-based disabilities, compared to not using it.
- Conditions
- Autism Spectrum Disorder, Cerebral Palsy, Epilepsy, Fetal Alcohol Spectrum Disorders
- Trial name
- NCT03852550
- Testing
- e-health application
- Where
- 9 sites in Canada
- Volunteers
- 52 people
- Sponsor
- McMaster University
Urinary Incontinence, Sarcopenia
Association Between Sarcopenia and Urinary Incontinence And Effect Of Physical Activity Among Over 50 Years Old Adults
As far as the investigators know, until this moment no research has investigated the prevalence of Sarcopenia in both sexes in Hungary.
- Trial name
- NCT05313360
- Where
- Hungary
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Pregnancy Related, Food Insecurity
Nourishing Beginnings: Addressing Food Insecurity During Pregnancy
This is a pilot project designed to test the feasibility of implementing a community health worker (CHW)-led intervention to improve nutritious food access and consumption among pregnant people and to evaluate the effectiveness…
- Conditions
- Pregnancy Related, Food Insecurity, Premature Birth, Pregnancy Complications
- Trial name
- NCT05341960
- Testing
- Food Delivery, Financial Support
- Where
- 2 sites in United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Intraepithelial Neoplasia
Genotypification and Predisposing Factors in Human Papilloma Virus Infection
Objective: Determine the genotypes and risk factors associated with human papilloma virus infection in Mexican women. Methods: It was a cross-sectional study of women attended at the Materno-Perinatal Hospital "Mónica Pretelini"…
- Trial name
- HPV (NCT01924117)
- Testing
- Linear Array HPV Genotyping assay
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Materno-Perinatal Hospital of the State of Mexico
End-stage Renal Disease, Hemodialysis
The Relationship Between Aortic Pulse Wave and Peripheral Artery Occlusion Disease in Hemodialysis Patients
Cardiovascular disease (CVD) is the leading cause of mortality in patients with end-stage renal disease (ESRD), which means that it is important to find out risk factors of CVD in order to prevent or treat it.
- Conditions
- End-stage Renal Disease, Hemodialysis, Aortic Calcification, Peripheral Artery Occlusion
- Trial name
- NCT01945255
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Fetal Hypoxia, Fetal Conditions
The Relationship Between Umbilical Cord ph and Feto-maternal Doppler Studies in Scheduled Nonlaboring Term Singleton Caesarean Deliveries
Perinatal asphyxia is a crucial reason for neonatal and childhood morbidity and death. Fetal and neonatal acidemia can be utilised as predictors for establishing such risk.
- Trial name
- NCT04364308
- Testing
- Fetal Echography
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Postpartum Depression, Pregnancy Related
Nurtured in Nature
The investigators pilot test a Nature Coach Intervention in a population of postpartum women, to increase the amount of time people spend outside in local nature, with the goal of preventing postpartum depression.
- Conditions
- Postpartum Depression, Pregnancy Related, Environmental Exposure
- Trial name
- NCT04146025
- Testing
- Nature Coach Intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Pennsylvania
Carpal Tunnel Syndrome Pregnancy
Pregnancy-Related Carpal Tunnel Syndrome Treatment
The current retrospective study aimed to compare the effectiveness of local steroid injection plus splinting with that of local steroid injection or splinting alone.
- Trial name
- NCT06375291
- Testing
- splint /steroid injection/both
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Mersin Training and Research Hospital
Premature Infants, Parent-Child Relations
Implementation of an Evidence Based Parentally Administered Intervention for Preterm Infants
Early developmentally-based behavioral intervention has well-established positive effects and is recommended as the standard of care to support early brain maturation, health, and development.
- Trial name
- NCT04555590
- Testing
- H-HOPE Intervention
- Where
- 4 sites in United States
- Volunteers
- 1,882 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Postpartum Recovery, Mother-infant Bonding
Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal Delivery
This prospective observational cohort study aims to evaluate the association between postpartum recovery quality and mother-infant bonding in women undergoing vaginal delivery.
- Conditions
- Postpartum Recovery, Mother-infant Bonding, Labor Pain
- Trial name
- NCT07582289
- Testing
- Labor Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ataturk University
Fibromuscular Dysplasia
Cohort Follow-up of Patients With Renal or Craniocervical Fibromuscular Dysplasia
PROFILE is a cohort study evaluating the progression of fibromuscular dysplasia lesions. This study is the prospective dimension of ARCADIA registry (ClinicalTrials.gov Identifier: NCT02884141), which aims to document phenotypic…
- Trial name
- PROFILE (NCT02961868)
- Testing
- Abdominal and supra-aortic trunks vascular imaging, Blood sampling (genetic), Blood sampling (biomarkers)
- Where
- 17 sites in Belgium, France
- Volunteers
- 340 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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