Clinical trials: Pregnancy Related Complications
Lung Transplant; Complications, Acute Kidney Injury
Association Between Renal Regional Oxygen Saturation Measured by Near-InfraRed Spectroscopy and Postoperative Renal Failure After Lung Transplantation Surgery: A Pilot Study
Complications after lung transplantation are almost ubiquitous, among which postoperative acute renal failure may represent more than 50% of lung transplant patients and require extrarenal purification in 5 to 13% of cases.
- Trial name
- SO-AKI-TP (NCT05836922)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Chronic Kidney Disease
Factors Related to the Progression of Chronic Kidney Disease
Chronic kidney disease is a progressive disorder that has been influenced with many factors. Most of the patients has altered Ca P metabolism and these dis orders are the contributing factors of the disease progression.
- Trial name
- NCT01317173
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Education and Research Hospital
Hepatorenal Syndrome
A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin
This study is designed to evaluate the efficacy and safety of intravenous terlipressin versus placebo for the treatment of type 1 hepatorenal syndrome (HRS) in participants receiving standard of care albumin therapy.
- Trial name
- NCT01143246
- Testing
- Terlipressin
- Where
- 73 sites in United States, Canada
- Volunteers
- 196 people
- Sponsor
- Mallinckrodt
Mental Health Issue, Substance Use Disorders
Improving Maternal Mental Health & SUD Screening and Treatment
The purpose of the study is to compare a text message-based mental health and substance use screening and referral to a treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care…
- Conditions
- Mental Health Issue, Substance Use Disorders, Postpartum Depression, Postpartum Anxiety
- Trial name
- NCT05764213
- Testing
- Listening to Women & Pregnant and Postpartum People
- Where
- United States
- Volunteers
- 10,469 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Fall, Congestive Heart Failure
Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase
Polypharmacy is common among older adults in the United States and is associated with harms such as adverse drug reactions and higher costs of care.
- Conditions
- Fall, Congestive Heart Failure, Chronic Kidney Failure, Adverse Drug Event
- Trial name
- NCT03791580
- Testing
- Commitment nudge, Justification nudge
- Where
- United States
- Sponsor
- RAND
Low Birth Weight, Prematurity
The Impact of Extreme Environmental and Security Conditions on Prematurity and Low Birth Weight Rates
Numerous reports indicate that various extreme environmental and security-related situations during pregnancy may increase the risk of prematurity, LBW, and miscarriage, as these events increase both the incidence and intensity…
- Trial name
- NCT07531134
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Acute Kidney Injury, Catheter-Related Complications
Ultrasound-Guided Percutaneous Peritoneal Dialysis Catheter Insertion for Urgent-Start Dialysis
This prospective observational study evaluates the feasibility, technical success, safety, and clinical outcomes of ultrasound-guided percutaneous peritoneal dialysis (PD) catheter insertion for urgent-start dialysis in pediatric…
- Conditions
- Acute Kidney Injury, Catheter-Related Complications, Pediatric Renal Disease
- Trial name
- NCT07847125
- Volunteers
- 50 people
- Sponsor
- Assiut University
Gestational Diabetes, Type 2 Diabetes
Relationship Between Gestational Diabetes and Type 2 Diabetes
The overall objective of this research project is to study the impact of preventive practices on the T2D-related risk profile among women with and without prior GDM and their children exposed and unexposed to GDM.
- Trial name
- GDM (NCT01340924)
- Where
- Canada
- Volunteers
- 450 people
- Sponsor
- Laval University
Severe Preeclampsia
Factors Associated With Blood Pressure Control Failure to Intravenous Labetalol in Severe Preeclampsia
Severe preeclampsia is a serious pregnancy complication that can lead to severe maternal and fetal outcomes, particularly when blood pressure is not adequately controlled.
- Trial name
- RELAPSE (NCT07547046)
- Where
- 14 sites in France
- Volunteers
- 350 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Neoplasms
MRI Functional Imaging Characteristics and Fat Quantification of CT-fat-free Renal Neoplasms: Relationships With Histological Classifications and Molecular Markers
The knowledge of the histological diagnosis and its subtype of a renal parenchymal tumor is important for determine whether the choice of a specific regimen of chemotherapy, target therapy and immunotherapy could be suitable and…
- Trial name
- NCT06126159
- Testing
- multiparametric and fat-detection magnetic resonance imaging (MRI)
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Chang Gung Memorial Hospital
Preterm Labor
Uterocervical Angle and Preterm Labour
To determine whether a novel ultrasonographic marker, uterocervical angle, correlates with risk of spontaneous preterm birth
- Trial name
- NCT04532086
- Testing
- Uterocervical angle
- Volunteers
- 197 people
- Sponsor
- Ain Shams Maternity Hospital
Endometriosis, Pelvic Pain
tDCS Versus tsDCS for Endometriosis-related Chronic Pelvic Pain Treatment
The purpose of the study is to compare the analgesic effect of 2 mA anodal direct current stimulation on the right primary motor cortex (M1) (tDCS) with a similar stimulation on the spine (D10) (tsDCS) in healthy volunteers (HV)…
- Conditions
- Endometriosis, Pelvic Pain, Transcranial Direct Current Stimulation, Spinal Cord Stimulation
- Trial name
- DCSErCPP (NCT02958423)
- Testing
- Transcranial DCS Healthy Volunteers, Transspinal DCS Healthy Volunteers, Transcranial DCS CPP patients
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jean Schoenen
Infertility, Female, Miscarriage
Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?
This study aims to explore the potential correlation between decreased ovarian reserve and previous history of early miscarriage.
- Conditions
- Infertility, Female, Miscarriage, Miscarriage, Recurrent, IVF
- Trial name
- NCT05969574
- Testing
- Transvaginal ultrasound, Blood test AMH
- Where
- 3 sites in United Arab Emirates
- Volunteers
- 2,059 people
- Sponsor
- ART Fertility Clinics LLC
Bladder Cancer
Gender Related Coping and Survivorship for Genitourinary Cancers
This research is being done to learn more about coping and survivorship of women with bladder cancer, specifically regarding psychosocial distress and sexual dysfunction.
- Trial name
- NCT05649306
- Testing
- Additional Education, Questionnaires, Attendance Diary
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Pregnancy Related, Pregnancy Loss
Microbiome and Malnutrition in Pregnancy
This study is being conducted to investigate how a mother's nutritional status and her gut microbiome during pregnancy contribute to the birth outcomes and health of her baby.
- Conditions
- Pregnancy Related, Pregnancy Loss, Pregnancy Complications, Pregnancy; Parasitic Disease
- Trial name
- MMIP (NCT04992104)
- Where
- 2 sites in Canada
- Volunteers
- 800 people
- Sponsor
- The Hospital for Sick Children
Obesity, Hormone Disturbance
Bariatric Surgery, Hormones, and Quality of Life
The purpose of this study is to characterize the hormonal status in fertile women undergoing laparoscopic gastric bypass, pre- and postoperatively, and evaluate if there is a correlation between health-related quality of life and…
- Conditions
- Obesity, Hormone Disturbance, Quality of Life, Hyperandrogenism
- Trial name
- OBLIV (NCT03188640)
- Testing
- Laparoscopic gastric-bypass surgery
- Volunteers
- 68 people
- Sponsor
- Linkoeping University
Preeclampsia
Biomarkers and Preeclampsia Outcomes
Prospective, observational, monocentric, non-interventional study.
- Trial name
- REPORTS (NCT03801447)
- Where
- Tunisia
- Volunteers
- 600 people
- Sponsor
- Dacima Consulting
Non-small Cell Lung Carcinoma (NSCLC), Melanoma
Study of CM-24 (MK-6018) Alone and In Combination With Pembrolizumab (MK-3475) in Participants With Selected Advanced or Recurrent Malignancies (MK-6018-001)
The purpose of this study is to evaluate the safety and tolerability of humanized IgG4 (kappa) isotype monoclonal antibody against CEACAM1 (CM-24 [MK-6018]), administered intravenously as monotherapy and in combination with…
- Conditions
- Non-small Cell Lung Carcinoma (NSCLC), Melanoma, Bladder Cancer, Colorectal Cancer
- Trial name
- NCT02346955
- Testing
- CM-24 (MK-6018), Pembrolizumab (MK-3475)
- Where
- 3 sites in United States, Israel
- Volunteers
- 27 people
- Sponsor
- Famewave Ltd.
Chronic Kidney Diseases, End Stage Renal Disease
The Effect of Exercise on Blood Parameters Related to Dialysis Patients' Survival
The purpose of this study is to check if patients' exercise during their dialysis sessions can improve the blood parameters which affect the heart disease and osteoporosis, so that we can help patients live longer.
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease, Hemodialysis
- Trial name
- NCT04916743
- Testing
- Intradialytic exercise group
- Where
- 2 sites in Iran
- Volunteers
- 44 people
- Sponsor
- Pardis Specialized Wellness Institute
Preterm, Surgery
An Exploratory Study of Arginine Supplementation and the Postoperative Immune REsponse
ASPIRE is a nutrition study focusing on the effect of arginine supplementation on immune function in postoperative infants. The investigators will explore the effect of current intravenous feeding (parenteral nutrition (PN))…
- Conditions
- Preterm, Surgery, Nutritional Deficiency, Immune System and Related Disorders
- Trial name
- ASPIRE (NCT05306925)
- Testing
- Arginine
- Where
- 2 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Liverpool
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