Clinical trials: Pregnancy Termination
Reproductive Health
Improving Person Centered Care for Post Abortion Patients in Kenya
The purpose of this study is to understand the effect of a phone based post-abortion intervention on the experience of post-abortion care.
- Trial name
- SPARQ_PACK (NCT04206514)
- Testing
- Person Centered Care - Post Abortion Support
- Where
- Kenya
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Arrhythmia, ECG Changes
Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy
In second trimester abortion above 22 weeks the investigators usually inject intra-cardiac Kcl for feticide. Digoxin intra-amniotic injection has been described in the literature in doses of 1-1.5 mg.
- Conditions
- Arrhythmia, ECG Changes, Hypotension
- Trial name
- NCT01951079
- Testing
- Intra-amniotic injection of DIGOXIN
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Birth Weight, Miscarriage
Micronutrient Supplementation Before and During 1st Pregnancy to Improve Birth Outcomes (JiVitA-5)
The purpose of this cluster-randomized trial is to evaluate the efficacy of daily, multiple micronutrient (MM) supplement versus identical placebo use among nulligravid, recently married women, starting preconceptionally through…
- Conditions
- Birth Weight, Miscarriage, Small-for-gestational Age, Preterm Birth
- Trial name
- JiVitA-5 (NCT03921177)
- Testing
- Multiple micronutrient supplement
- Where
- Bangladesh
- Volunteers
- 9,859 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Pain, Pregnancy
Efficacy Study of Prophylactic Ibuprofen Versus Placebo on Pain Relief and Success Rates of Medical Abortion
In the current study, we want to evaluate the prophylactic use of ibuprofen versus a placebo for medical abortion by mifepristone and misoprostol, at a gestational age of up to 7 weeks, in regard to the effect on pain relief and…
- Trial name
- NCT00997074
- Testing
- ibuprofen
- Where
- Israel
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Spontaneous Abortion
Knowledge, Attitude and Practices of Flemish Midwifes Regarding Spontaneous Abortion
KAP-study in Flemish midwives with intramural employment
- Trial name
- KAP-abortion (NCT02657200)
- Testing
- survey
- Where
- Belgium
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- VakgroepVolksgezondheidEnEerstelijnszorg
Abortion, Second Trimester
Uterocervical Angle in the Termination of Second Trimester Pregnancy
To evaluate the performance of uterocervical angle (UCA) in the prediction of second trimester terminations.
- Trial name
- NCT03220607
- Testing
- uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Hemorrhage
Uterotonic Prophylaxis Trial
Excessive bleeding after dilation and evacuation (D\&E) requiring interventions is common, occurring in approximately 30% of cases at one large abortion-providing clinic.
- Trial name
- UPT (NCT02408965)
- Testing
- Methergine
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cervical Insufficiency, Preterm Birth
Investigation Into the Microorganisms in Pregnant Women
Pregnant women with short cervical length (<25 mm) in second-trimester ultrasonographic assessment are at high risk for preterm birth, a major cause of perinatal mortality and morbidity worldwide.
- Trial name
- NCT04688866
- Testing
- Sequencing
- Where
- Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Recurrent Pregnancy Losses, Positive Anti Phospholipid Syndrome
Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome
Preconceptional use of low molecular weight heparin (enoxaparin) and aspirin in patient with recurrent miscarriages with positive anti phospholipid antibodies increase the implantation rate and the duration of pregnancy with low…
- Trial name
- NCT01661439
- Testing
- low molecular weight heparin (enoxeparine)
- Where
- Egypt
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Pregnancy; Habitual Aborter, Weeks of Gestation 37 or More
Accuracy and Reliability of Fetal Heart Rate and Uterine Contraction Monitoring Method
Clinical Investigation Protocol for a study designed to determine the equivalence of the Monica AN24 monitor to Philips 50XM for fetal heart rate (FHR) and uterine contraction (UC) monitoring during labor.
- Trial name
- NCT01280357
- Testing
- Monica AN24 (K101081), Philips 50XM
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monica Healthcare Ltd
Surgical Abortion, Patient Satisfaction
Effects of Aromatherapy on Patient Satisfaction With Surgical Abortion at Less Than 10 Weeks Gestation
The investigators propose a single-site, double-blinded, placebo-controlled clinical trial of lavender aromatherapy versus placebo for patient satisfaction in adult women having a surgical abortion before 10 weeks and 0 days…
- Conditions
- Surgical Abortion, Patient Satisfaction, Anesthesia, Pain
- Trial name
- NCT04969900
- Testing
- Lavender oil.
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vitamin D Deficiency, Recurrent Miscarriage
The Cohort Study of the Correlation Between Serum 25(OH)D Level and Pregnancy Outcome
The objective of this single-center prospective observational study is to clarify the trend of maternal serum 25(OH)D levels before pregnancy and during pregnancy, and to explore the correlation between serum 25(OH)D levels and…
- Conditions
- Vitamin D Deficiency, Recurrent Miscarriage, Pregnancy Related
- Trial name
- NCT05824897
- Testing
- Serum levels of vitamin D
- Where
- China
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Aimin Zhao
Pregnancy of Unknown Location, Ectopic Pregnancy
Assessment of Biomarkers in Pregnancy on Unknown Location and Ectopic Pregnancy
To further develop the patient care pathway for women classified with a pregnancy of unknown location (PUL) and ectopic pregnancy (EP).
- Conditions
- Pregnancy of Unknown Location, Ectopic Pregnancy, Early Pregnancy, Early Pregnancy Loss
- Trial name
- ABPEP (NCT04738370)
- Testing
- Sample collection
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Abortion Seekers
Mifepristone at Same Time Multicenter Study
This is a multicenter, randomized study. 564 healthy women, age 18 years or older, with an intrauterine pregnancy, and requesting a medical abortion, will be recruited to participate in this prospective clinical trial.
- Trial name
- MAST (NCT00269568)
- Testing
- mifepristone and misoprostol
- Where
- 4 sites in United States
- Volunteers
- 1,128 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Legally Induced Abortion Without Mention of Complication
A Comparison of Sublingual and Buccal Misoprostol Regimens After Mifepristone for Mid-trimester Abortion
The primary goal of this study is to directly compare repeat doses of sublingual and buccal routes of 400 mcg misoprostol following mifepristone for second trimester abortion in order to determine if sublingual route confers an…
- Trial name
- NCT02708446
- Testing
- Mifepristone, Buccal misoprostol, Sublingual misoprostol
- Where
- 4 sites in Armenia, Nepal and 2 more
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Simplifying Menstrual Regulation (MR): Post Abortion Care in Pakistan
This study is an additional component of protocol 6005, titled Simplifying Menstrual Regulation (MR): Exploring the role of at-home semi-quantitative pregnancy tests for follow-up to menstrual regulation service provision in…
- Trial name
- NCT02343913
- Testing
- PAC checklist
- Where
- 15 sites in Pakistan
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Surgical Abortion
Patient Support During Surgical Abortion
This study will be a non-blinded randomized controlled trial (RCT) of women presenting for abortion at <13 6/7 weeks. Women will be randomized either to receive support by a trained abortion doula (intervention) or to have…
- Trial name
- NCT01937988
- Testing
- Doula Arm
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pregnancy Termination
Comparing Two Regimens for Medical Abortion: Mifepristone+Misoprostol Versus Misoprostol Alone
A double blinded, placebo-controlled randomized trial to compare the safety, efficacy and acceptability of two medical abortion regimens up to 63 days' LMP.
- Trial name
- NCT00680394
- Testing
- mifepristone, misoprostol
- Where
- 2 sites in Tunisia, Vietnam
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Infertility
Prevalence of Uterine Malformations in Newly Married Unselected Population
Uterine malformation is occur due to the abnormal development of Mullerian canal during embryogenesis and it is known that it reduces the fertility and live birth rate and also increases the abortion and preterm birth rate.
- Trial name
- NCT04686227
- Testing
- 3D Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pregnancy Complications
Measuring sVAP-1 as a Predictor of Pregnancy Problems
Pre-eclampsia is a common pregnancy disorder defined as high blood pressure and protein in the urine after 20 weeks of pregnancy.
- Trial name
- NCT04891315
- Testing
- Blood test for soluble VAP-1 (sVAP-1).
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Leicester