Clinical trials: Pregnancy Termination
Miscarriage
Serum Kisspeptin: a Predictive Marker of Miscarriage or Not?
This is a prospective observational study. Eligible women undergo ART treatment in our centre will be recruited for the study and each woman will only be included in the study once. Informed written consent will be obtained.
- Trial name
- NCT03940495
- Where
- China
- Volunteers
- 182 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Recurrent Implantation Failure, Recurrent Pregnancy Loss
Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss
The IMERR study aims to improve understanding of certain causes of infertility related to recurrent implantation failure (RIF) and/or recurrent pregnancy loss (RPL), conditions that affect many women undergoing assisted…
- Conditions
- Recurrent Implantation Failure, Recurrent Pregnancy Loss, Infertility, Female, Endometrial Diseases
- Trial name
- IMERR (NCT07265505)
- Testing
- Endometrial Biopsy, Vaginal Swab, Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Frozen Embryo Transfer, Polycystic Ovarian Disease
Letrozole Versus Hormonal Preparation in Frozen Cycles of PCOS Patients.
One of the indications of freezing is to reduce the risk of ovarian hyperstimulation syndrome particularly in polycystic ovarian disease (PCOS) women.
- Conditions
- Frozen Embryo Transfer, Polycystic Ovarian Disease, Letrozole, Hormone Replacement Therapy
- Trial name
- NCT05168865
- Testing
- Letrozole 2.5mg
- Sponsor
- Dubai Fertility Center
Pregnancy
Techniques to Improve Efficacy of Second Trimester Medical Termination
Interruption of a pregnancy after 14 weeks gestation may be required when the fetus is dead, severely malformed or in cases of maternal illness.
- Trial name
- NCT00864799
- Testing
- Misoprostol
- Where
- Australia
- Volunteers
- 302 people
- Sponsor
- King Edward Memorial Hospital
Medical Abortion
Treatment Regimens for Mifegyne and Cytotec
The purpose of this study is to test two regimens of mifegyne and cytotec for medical abortion. The investigators hypothesize that administration of both medications during one hospital visit will not compromise effectiveness.
- Trial name
- NCT00920465
- Testing
- mifegyne and cytotec
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Western Galilee Hospital-Nahariya
Uterine Curettage, Abortion, Induced
Evaluation of Different Anesthesia for Uterine Curettage
Anesthesia during uterine curettage is a problem. Paracervical block is used in general for such an operation, though, the anesthetic efficacy is incomplete.
- Trial name
- EDAUC (NCT00733564)
- Testing
- Lidocaine, Propofol, Sevoflurane
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanjing Medical University
Female, Recurrent Miscarriage
Assessment of Natural Killer Cells in Unexplained Recurrent Pregnancy Loss
To assess natural killer cells frequency and activation in cases of unexplained recurrent abortion in comparison to fertile cases 2. . To study the expression of stimulatory receptors of natural killer cell.
- Conditions
- Female, Recurrent Miscarriage, Unexplained Pregnancy Loss
- Trial name
- NCT03941470
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Contraception
A Comparison of Continuation Rates for Three Hormonal Contraceptive Methods
This study will assess the continuation rates among women using oral contraceptive pills, Depo-Provera and Ortho Evra following a first trimester abortion.
- Trial name
- NCT00253019
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Emory University
Labor Induction
Factors Influencing the Abortion Interval of Second-trimester Termination of Pregnancy Using Misoprostol
This study aims to analyze the factors influencing the abortion interval of second-trimester termination of pregnancy using misoprostol.
- Trial name
- NCT01927822
- Where
- Taiwan
- Volunteers
- 101 people
- Sponsor
- Far Eastern Memorial Hospital
Maternal-Fetal KIR-HLA-C Compatibility
PREDICTIVE IMMUNOLOGICAL STUDY OF RECURRENT ABORTIONS AND IMPLANTATION FAILURE
The involvement of the immune system in the process of implantation and its modulation as a therapeutic line in these alterations, failure of implantation and repetition abortion are controversial and make it necessary to conduct…
- Trial name
- NCT04052438
- Testing
- HLA-C and KIR determination for patients, couples, oocyte or semen donors, abortive tissue and newborn.
- Volunteers
- 200 people
- Sponsor
- IVI Madrid
Legal Abortion With Complication, Pain
Paracervical Block for Pain Control in First Trimester Abortion
Many woman undergoing a surgical abortion receive a paracervical nerve block for pain reduction, in which lidocaine (a numbing medication) is injected around the cervix.
- Trial name
- NCT01094366
- Testing
- Paracervical Block
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Medical Abortion
The Acceptability and Feasibility of an Alternative to Routine Follow-up Visit After Medical Abortion in Vietnam
This trial will compare the efficacy and acceptability of post-medical abortion follow-up by assigning women to either 1) alternative follow-up via routine semi-quantitative pregnancy test and a self-administered follow-up…
- Trial name
- NCT01150422
- Testing
- Alternative follow-up
- Where
- 4 sites in Vietnam
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Induced
Cervical Priming Before Dilation & Evacuation
The purpose of this study is to compare the efficacy of buccal misoprostol cervical priming to laminaria priming among women undergoing D\&E at 13-20 weeks gestation in the Western Cape Province, South Africa
- Trial name
- NCT01597726
- Testing
- Misoprostol, Laminaria
- Where
- South Africa
- Volunteers
- 159 people
- Sponsor
- Ibis Reproductive Health
Pre-Eclampsia
Hydroxychloroquine May be Beneficial for Preeclampsia
The purpose of this research is to investigate the impact of hydroxychloroquine on the incidence of hypertensive pregnancy disorders in women with a history of recurrent spontaneous abortion (RSA).
- Trial name
- NCT06020378
- Testing
- Hydroxychloroquine
- Where
- China
- Volunteers
- 462 people
- Sponsor
- RenJi Hospital
Maternal Care Patterns, Pregnancy Related
Cash Benefits and Reproductive/Perinatal Health
During the first two years of the COVID-19 pandemic, the City of Chelsea, Massachusetts held a lottery to allocate cash benefits to its residents for ten months.
- Conditions
- Maternal Care Patterns, Pregnancy Related, Miscarriage
- Trial name
- NCT05782660
- Testing
- Cash Benefit, No Cash Benefit
- Where
- United States
- Volunteers
- 3,615 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Abortion
Impact of Video Intervention on Postabortal Uptake of Long Acting Reversible Contraception (LARC)
Primary: To compare rates of immediate postabortal LARC uptake between women exposed to a brief, theory-based, video intervention prior to standard contraceptive counseling and women exposed to standard counseling alone.
- Trial name
- LARC IUD (NCT01945385)
- Testing
- Video intervention
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Abortion, Induced, Abortion, Second Trimester
Mifepristone and Mid-Trimester Termination of Pregnancy
Mid-second trimester medical terminations of pregnancy require admission to the hospital for the length of time it takes a woman to abort.
- Trial name
- NCT00382538
- Testing
- Addition of mifepristone 200 mg 24 hours before induction
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston University
Subclinical Hypothyroidism, Infertility
Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation
Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) with normal free thyroxine (fT4) levels.
- Conditions
- Subclinical Hypothyroidism, Infertility, Assisted Reproductive Technology, In Vitro Fertilization (IVF)
- Trial name
- LESI (NCT07257250)
- Where
- 2 sites in Vietnam
- Volunteers
- 900 people
- Sponsor
- Mỹ Đức Hospital
Incomplete Abortion
Sublingual Misoprostol Versus Standard Surgical Care for the Treatment of Incomplete Abortion in Nigeria
Women diagnosed with incomplete abortion in this health facility will be randomized to receive one of the following regimens: 400 mcg sublingual misoprostol in one dose or standard surgical treatment (MVA).
- Trial name
- NCT01539408
- Testing
- Misoprostol, surgery Manual vacuum aspiration (MVA)
- Where
- 2 sites in Nigeria
- Volunteers
- 90 people
- Sponsor
- Gynuity Health Projects
Abortion
Side Effects and Adherence Associated With Doxycycline Use Following Medical Abortion
The effectiveness of antibiotic treatment at reducing post-abortion infection is unclear. The experiences of women prescribed routine antibiotics after medical abortion is missing from the existing evidence.
- Trial name
- NCT01799252
- Where
- 7 sites in United States
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects