Clinical trials: Pregnancy Termination
Uterine Cervical Incompetence
Cervical Occlusion for the Prevention of Preterm Birth
The aim of this study was to evaluate the effect of cervical occlusion versus no cervical occlusion in women with cervical cerclages.
- Trial name
- NCT01737788
- Testing
- Cervical occlusion
- Where
- 23 sites in Australia, Denmark and 7 more
- Volunteers
- 309 people
- Sponsor
- Niels Jørgen Secher
Missed Abortion
Sublingual vs Vaginal Misoprostol for Termination of First Trimesteric Missed Abortion
Efficacy of sublingual versus vaginal misoprostol in termination of first trimester missed abortion
- Trial name
- NCT05001061
- Testing
- Misoprostol Pill
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Cairo University
Induced Abortion
Study of Sublingual Versus Oral Misoprostol Administration Following Mifepristone 200 mg for Abortion up to 63 Days Gestation
This open-label, randomized study is being conducted to determine whether a dose of 400 mcg of sublingual misoprostol (i.e., under the tongue) taken 24 hours following administration of mifepristone 200 mg is effective and…
- Trial name
- NCT00286208
- Testing
- Mifepristone, misoprostol
- Where
- 9 sites in Moldova, Tunisia and 1 more
- Volunteers
- 1,443 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Missed Abortion
Effects of Mandala Coloring in Missed Abortion
This randomized controlled study aims to evaluate the effects of mandala coloring activity on stress, anxiety, pain, and physiological parameters in women diagnosed with missed abortion.
- Trial name
- NCT07420413
- Testing
- Mandala Coloring Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Selcuk University
Missed Abortion, Incomplete Abortion
The Role of Uterine Artery Doppler Parameters in the Management of Retained Products of Conception.
During the recent decades the need for surgical evacuation of the uterus in early miscarriages and incomplete miscarriages has been questioned.
- Conditions
- Missed Abortion, Incomplete Abortion, Uterine Gestational Residua, Uterine Artery Doppler
- Trial name
- NCT01775917
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Carmel Medical Center
Infertility, Aneuploidy
The Effect of Acupuncture on Pregnancy Rates in Women Undergoing in Vitro Fertilization With Preimplantation Genetic Screening
While IVF offers an effective treatment for infertility, a significant proportion of IVF cycles still result in failed implantation and early miscarriage.
- Trial name
- NCT03981120
- Testing
- Laser and Traditional Acupuncture
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chromosome Translocation, Genetic Disorders in Pregnancy
Investigation and Diagnosis of the Chromosome Variation in Donated/abandoned Blastocyst
Blastocysts derived from patients seeking infertility treatment were generated by in vitro fertilization and embryo culture as previously described, and were evaluated using the Gardner system.
- Conditions
- Chromosome Translocation, Genetic Disorders in Pregnancy, Recurrent Miscarriage
- Trial name
- NCT05216068
- Testing
- NGS
- Where
- Taiwan
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Hydatidiform Mole (Diagnosis), Abortion, Spontaneous
The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles
This is a prospective observational study assessing which ultrasound findings are best at excluding a molar pregnancy in first trimester miscarriage.
- Conditions
- Hydatidiform Mole (Diagnosis), Abortion, Spontaneous, Missed Abortion, Incomplete Miscarriage
- Trial name
- NCT05516810
- Where
- 2 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- King's College Hospital NHS Trust
Induced Abortion, First Trimester Abortion
Study of Clinic-based Versus Self-use of Medical Abortion Pills
The goal of the study is to determine whether important clinical outcomes differ among women who access a combined medical abortion regimen from a pharmacy when compared with those who access it from a facility.
- Conditions
- Induced Abortion, First Trimester Abortion, Misoprostol, Mifepristone
- Trial name
- MOC (NCT03727308)
- Testing
- Medical abortion pills sourced from pharmacies, Medical abortion pills sourced from health clinics
- Where
- 2 sites in Cambodia, Ghana
- Volunteers
- 4,196 people, healthy volunteers welcome
- Sponsor
- Ipas
Habitual Abortion
CXCL9 and CXCL11 Levels in Patients With Autoimmune Thyroiditis and Habitual Abortions
The purpose of this study is to measure serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
- Trial name
- NCT01644318
- Where
- Turkey (Türkiye)
- Sponsor
- Ankara Education and Research Hospital
Abortion, Missed
Misopristol Versus Pitocin for Second Trimester Abortion
Second trimester abortion can be done surgically or medically. Medical abortion with mifepristone and misopristol is one of the common protocol, but misopristol have high rate side effect.
- Trial name
- NCT00784797
- Testing
- mifepristone and misopristol, mifepristone and oxytocin
- Where
- Israel
- Volunteers
- 145 people
- Sponsor
- Hadassah Medical Organization
Pregnancy Related
Pharmacological Voluntary Termination of Pregnancy: Predictors of Pelvic Pain During Treatment
Pharmacological treatment for voluntary termination of pregnancy is a safe and effective practice, but has as its limitation a greater need for analgesic coverage than surgical treatment.
- Trial name
- NCT06800287
- Where
- 2 sites in Italy
- Volunteers
- 13 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Early Pregnancy
Conversational AI Platform for Early Pregnancy Care City-wide Recruitment: A Feasibility Study
This study seeks to determine pregnant patients in the Philadelphia area can be recruited to a conversational AI texting platform.
- Trial name
- CIRCA (NCT07197892)
- Testing
- CIRCA Texting Platform
- Where
- United States
- Volunteers
- 2,637 people
- Sponsor
- University of Pennsylvania
Contraception
A Trial of Group Versus Individual Family Planning Counseling in Ghana
This study uses a randomized, noninferiority design to determine whether group family planning counseling is as effective as individual family planning counseling among gynecological patients with unmet need at two teaching…
- Trial name
- GCFP (NCT00814411)
- Testing
- group family planning counseling, Individual family planning counseling
- Where
- 3 sites in United States, Ghana
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Surgical Abortion
Cervical Preparation for Surgical Abortion at 12-14 Weeks: a Prospective, Randomized, Evaluator-blinded, Multicenter, Controlled Comparison Between Mifepristone, Misoprostol and Their Combination
More than 100 000 surgical abortions are annually performed in France. About four in ten women will have an abortion in their life.
- Trial name
- NCT01795599
- Testing
- Mifegyne ®, Gymiso®
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Anesthesia, Abortion Early
Remimazolam Versus Propofol for Painless Abortion
The goal of this clinical trial is to compare the efficacy and safety of propofol vs. remimazolam in combine use of esketamine in women with early pregnancy undergoing painless abortion.
- Trial name
- NCT05635955
- Testing
- Remimazolam, Propofol, Esketamine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Early Abortion
Advance Provision of Medication Abortion
This mixed-methods study follows a prospective cohort of participants receiving Mifeprex® (mifepristone) by a clinician in advance of a potential unintended pregnancy.
- Trial name
- NCT03829696
- Testing
- Mifeprex® (Mifepristone 200 mg), Misoprostol 800 mcg, ella® (ulipristal acetate emergency contraception 30 mg)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Recurrent Pregnancy Loss, Miscarriage
Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss
Recurrent pregnancy loss (RPL) affects 5% of couples trying to achieve parenthood. Most cases of RPL are unexplained and have no effective treatment to improve the likelihood of a pregnancy resulting in a live birth.
- Trial name
- NCT02379650
- Testing
- Hydroxychloroquine (HCQ)
- Where
- 2 sites in United States
- Sponsor
- University of Utah
Salpingectomy, Hysterectomy
Analysis of the Molecular Composition of Tubal Cilia in Patients With or Without Ectopic Pregnancy
Primary Ciliary Dyskinesia associated with abnormalities of lateralization of organs (with existence of a situs inversus in 50% of cases) and secondary fertility disorders related in humans to abnormalities of mobility of sperm…
- Conditions
- Salpingectomy, Hysterectomy, Primary Ciliary Dyskinesia, Ectopic Pregnancy
- Trial name
- CILTUBE (NCT05374720)
- Testing
- salpingectomy, hysterectomy
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Intra Uterine Fetal Death
Misoprostol for Second Trimester Pregnancy Termination
The majority of second-trimester pregnancy termination performed in the United States are performed surgically by dilation and evacuation. The frequency of induction of abortion increases as gestational age advances.
- Trial name
- MIS (NCT02669420)
- Testing
- termination of second trimester pregnancy
- Volunteers
- 180 people
- Sponsor
- Assiut University