Clinical trials: Pregnancy Termination
Pregnancy, Spontaneous Abortions
Study of the Best Blastocyst Post Transfer by aCGH
An Observational, blind and prospective study of Preimplantational Aneuploidy Screening by aCGH in Trophectoderm Biopsy
- Conditions
- Pregnancy, Spontaneous Abortions, Stillbirth
- Trial name
- NCT01664546
- Testing
- Trophectoderm biopsy
- Where
- Argentina
- Volunteers
- 150 people
- Sponsor
- University of Buenos Aires
Birth Defect, Spontaneous Abortions
Nplate® Pregnancy Exposure Registry
US study to estimate the prevalence at birth of major birth defects (ie, those that cause significant functional or cosmetic impairment, require surgery, or are life-limiting) in children born to mothers who have received Nplate®…
- Conditions
- Birth Defect, Spontaneous Abortions, Low Birth Weight
- Trial name
- NPER (NCT02090088)
- Testing
- Not applicable- observational study
- Volunteers
- 4 people
- Sponsor
- Amgen
Abortion
Gestational Age is Underestimated by Menstrual Dating Compared to Ultrasound Dating in Those Undergoing Abortion up to 20 Weeks
Several large trials report gestational dating by last menstrual period (LMP) overestimates gestational age (GA) vs. ultrasound (US) by approximately one week. Previous studies examined only term pregnancies.
- Trial name
- NCT00884403
- Where
- Canada
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Abortion, Induced
Study of 400mcg Sublingual Versus 400mcg Buccal Misoprostol Following 200mg Mifepristone for Medical Abortion up to 63 Days Last Menstrual Period (LMP)
This open-label, randomized study is being conducted to determine whether a dose of 400 mcg of buccal misoprostol (i.e., in the cheek) taken 24 hours following administration of mifepristone 200 mg is as effective and acceptable…
- Trial name
- NCT00870272
- Testing
- Misoprostol
- Where
- Moldova
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Threatened Abortion
Pregnancy Outcome in Woman With Threatened Abortion
The study aims to quantify the relations between first \& second trimester bleeding and maternal \& neonatal morbidity. Additionally, the study will help in assessing the risk for abortions in women with threatened abortions and…
- Trial name
- POTA (NCT02686112)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Pregnancy Trimester, Second, Induced Abortion
Randomized Trial Comparing Misoprostol and Foley Bulb for Pregnancy Termination in the Second Trimester
The purpose of this study is to compare two methods of pregnancy termination on the time to delivery in the second trimester.
- Trial name
- NCT00324519
- Testing
- Foley bulb, misoprostol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pregnancy Loss, Early
Biochemical Pregnancy Loss. A Multicenter Retrospective Study
Biochemical pregnancy loss (BPL) is a very frequent issue in human reproduction. After the implantation of the embryo, hCG disappears very soon from the maternal bloodstream and no evidence of a clinical pregnancy is seen.
- Trial name
- BPL (NCT04549909)
- Testing
- collect retrospectively data
- Where
- Spain
- Volunteers
- 20,000 people
- Sponsor
- IVI Vigo
Pregnancy, Miscarriage
Aspirin, Heparin and Miscarriage
Efficacy of low dose aspirin (LDA) versus LDA plus low-molecular-weight-heparin (LMWH) in patients with a history of recurrent miscarriages.
- Trial name
- NCT01917799
- Testing
- Aspirin, Heparin
- Where
- Libya
- Volunteers
- 150 people
- Sponsor
- University of Khartoum
Abortion Early
Point of Care Tests in the Management of Very Early Medical Abortion
This study will investigate the use of a point of care test in patients who are having an abortion at a gestation of <6 weeks (known as a very early medical abortion).
- Trial name
- POCT VEMA (NCT07417787)
- Testing
- Blood test, Participant Questionnaire
- Where
- 3 sites in Sweden, United Kingdom
- Volunteers
- 130 people
- Sponsor
- University of Edinburgh
Second Trimester Abortion
Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion
the investigators aimed to study the efficacy and safety of nitric oxide donors when combined with prostaglandins in induction of second trimester abortion expecting that both drugs when used together will be of greater…
- Trial name
- NCT03407521
- Testing
- Misoprostol, isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abortion, Induced
Cervical Priming Before Dilation & Evacuation
The purpose of this study is to compare the efficacy of buccal misoprostol cervical priming to laminaria priming among women undergoing D\&E at 13-20 weeks gestation in the Western Cape Province, South Africa
- Trial name
- NCT01597726
- Testing
- Misoprostol, Laminaria
- Where
- South Africa
- Volunteers
- 159 people
- Sponsor
- Ibis Reproductive Health
Missed Abortion
Comparison of Efficacy and Safety of Oral Versus Vaginal Misoprostol in Missed Abortion in First Trimester of Pregnancy
Incomplete abortion has an eminent clinical diagnosis and is characterized by transvaginal bleeding associated with an open uterine cervix upon physical examination when the products of conception have not been wholly discharged.
- Trial name
- NCT07526064
- Testing
- Oral misoprostol, Misoprostol (given vaginally)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Hamna Khaliq
Abortion, Induced
Comparison of the Safety of First Trimester Abortions Performed by Physicians and Non-Physicians in South Africa and Viet Nam.
There have been no studies in developing countries assessing the safety of midlevel providers (MLP) compared to physicians in performing first-trimester manual vacuum aspiration abortion.
- Trial name
- NCT00370487
- Volunteers
- 2,860 people, healthy volunteers welcome
- Sponsor
- World Health Organization
Abortion Complication
Abortion-related Morbidity and Mortality in Conflict-affected and Fragile Settings Study
To describe and estimate the burden of abortion-related complications, particularly near-miss complications and deaths, and their associated factors among women presenting for abortion-related complications in health facilities…
- Trial name
- AMoCo (NCT04331847)
- Where
- 3 sites in Central African Republic, Democratic Republic of the Congo and 1 more
- Volunteers
- 2,500 people
- Sponsor
- Epicentre
Termination of Pregnancy
Obstetric & Pediatric Evolution Following Parental Refusal for Early Termination of Pregnancy Despite Fetal Risk
More and more parents decide to maintain pregnancy which could have been interrupted because of serious fetal pathologies. In this observational study, the investigators examine obstetrical and pediatric evolution of these…
- Trial name
- NCT03393455
- Testing
- not accurate
- Where
- France
- Volunteers
- 211 people
- Sponsor
- University Hospital, Montpellier
Abortion in First Trimester, Abortion, Second Trimester
Second-trimester TOP : a Retrospective Study Comparing Complications at 12-14 vs 14-16 Weeks of Gestation
In France, the recently adopted law relating to the legal time limit for access to voluntary interruption of pregnancy has set a threshold of the term at which it can be performed up to 16 weeks of gestation.
- Trial name
- NCT05469594
- Volunteers
- 122 people
- Sponsor
- Central Hospital, Nancy, France
Reproductive Health
Improving Person Centered Care for Abortion Clients in India
The purpose of this study is to understand the effect of providing pharmacists in UP, India with additional information about medication abortion.
- Trial name
- SPARQ_ACI (NCT04307641)
- Testing
- 2 Page Information Sheet
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Thrombophilia With Recurrent Pregnancy Loss
Diagnosis and Treatment Strategy of Recurrent Spontaneous Abortion Associated With Thrombophilla
In this clinical cohort study, the investigators observe the efficacy of low molecular weight heparin in the treatment of thrombophilia with recurrent pregnancy loss with a prospective randomized controlled trial.
- Trial name
- NCT02986594
- Testing
- Aspirin, Heparin
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Social Stigma, Pregnancy
A Pre and Post Test Intervention Design to Prevent Abortion and Contraceptive-use Stigma Among School Youths in Kenya
In many low-income countries, unsafe abortion is recognized as a leading cause of maternal morbidity and mortality. Social stigma surrounding abortion and contraceptive use plays a critical role in the social, medical, and legal…
- Conditions
- Social Stigma, Pregnancy, Contraception
- Trial name
- SAC (NCT03065842)
- Testing
- Abortion- and contraceptive-use stigma reduction program, Usual Standards
- Where
- Kenya
- Volunteers
- 1,207 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Focus: Pre-residency Intention to Provide Abortion
Beliefs and Practice Intentions of Future Ob/Gyn Residents Regarding Reproductive Healthcare
The objective of this study is to ascertain factors shaping medical students' pre-residency intention to provide abortion through an in-depth qualitative investigation into the context and experiences that shape intention to…
- Trial name
- NCT01763073
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital