Clinical trials: Pregnancy Termination
Recurrent Implantation Failure, Recurrent Pregnancy Loss
Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss
The IMERR study aims to improve understanding of certain causes of infertility related to recurrent implantation failure (RIF) and/or recurrent pregnancy loss (RPL), conditions that affect many women undergoing assisted…
- Conditions
- Recurrent Implantation Failure, Recurrent Pregnancy Loss, Infertility, Female, Endometrial Diseases
- Trial name
- IMERR (NCT07265505)
- Testing
- Endometrial Biopsy, Vaginal Swab, Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abortion Stigma
Measurement of Individual Level of Abortion Stigma Study
This study is a randomized controlled trial designed to measure abortion stigma related to the Pennsylvania Abortion Control Act.
- Trial name
- NCT02672605
- Testing
- Pennsylvania State Abortion Consent
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Pennsylvania
Threatened Miscarriage in First Trimester
Value of CA125 and Yolk Sac Morphology in Prediction of Pregnancy Outcome in Threatened Miscarriage
evaluation of serum CA125 level and yolk sac morphology in women with threatened miscarriage is very important to predict pregnancy outcome
- Trial name
- NCT03320213
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Therapeutic Abortion With Complications, Personality Disorders
Therapeutic Termination of Pregnancy and Psychiatric Implications
25 parental couples, with a prenatal diagnosis of fetal abnormality, had psychiatric evaluation for eligibility before TToP and after one year from the procedure.
- Conditions
- Therapeutic Abortion With Complications, Personality Disorders, Trauma, Psychological, Reproductive Behavior
- Trial name
- TTOP_PSY (NCT04080141)
- Testing
- Multiple psychometric questionnaire, Clinical psychiatric examination
- Volunteers
- 90 people
- Sponsor
- University of Milano Bicocca
Alive and Viable Births
Prevention of Unexplained Recurrent Abortion by Enoxaparine
Standard investigations fail to reveal any apparent cause in 50% of the cases of recurrent spontaneous abortion. Prothrombotic mechanisms were initially evoked.
- Trial name
- PREFIX (NCT00740545)
- Testing
- enoxaparine 40 mg daily
- Where
- 7 sites in France
- Volunteers
- 258 people
- Sponsor
- University Hospital, Brest
Infertility, Preimplantation Genetic Diagnosis/Screening
Estradiol, Progesterone and Endometrial Thickness in Frozen Euploid Embryo Transfer
The development and improvement in Preimplantation genetic diagnosis/screening (PGS) in association with the efficacy and security of vitrification and trophectoderm biopsy, more efficient stimulation schemes and laboratory…
- Conditions
- Infertility, Preimplantation Genetic Diagnosis/Screening, Miscarriage
- Trial name
- NCT03395665
- Testing
- Estradiol level, Progesterone level, Endometrial thickness
- Where
- Spain
- Volunteers
- 299 people
- Sponsor
- Fundacion Dexeus
Sexual Violence, Abortion
Impact of Sexual Violence on the Incidence of Voluntary Termination of Pregnancy in La Réunion
According to the figures for the last three years collected from the Indian Ocean Regional Health Observatory, it appears to be about twice as many voluntary terminations of pregnancy on the island of Reunion compared with France…
- Trial name
- IVIIRun (NCT05471895)
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pregnancy Loss
Cervical Length on Pregnancy Termination
Cervical length is used as a parameter to predict cervical insufficiency and onset of labor. However, its role in predicting abortion induction is unclear.To investigate the impact of cervical length measurement and fetal…
- Trial name
- NCT04013035
- Testing
- cervical length measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pregnancy Related
Requests for Medical Termination of Pregnancy for Psychological or Social Maternal Reasons
When the request for termination of pregnancy is made at a term of less than sixteen weeks of amenorrhea, the patients have complete decision-making autonomy. This is called voluntary termination of pregnancy.
- Trial name
- NCT05499325
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Pain
Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion
The investigators theorize that the application of a lidocaine-prilocaine cream 5-10 minutes prior to the administration of a paracervical block could decrease pain associated with its administration and pain with abortion…
- Trial name
- NCT03508804
- Testing
- Lidocaine-Prilocaine Cream, 1% Lidocaine Paracervical Block
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Miscarriage
Mucosal-Associated Invariant T Cells in Cases of Miscarriage
Miscarriage is the most frequently encountered complication of pregnancy ranging from 10% to 30%. The etiology of recurrent spontaneous miscarriage (RSM) in 40%-50% of cases cannot be identified.
- Trial name
- NCT04492098
- Testing
- MAIT cells
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Termination of Pregnancy
Comparison of Surgical Versus Medical Termination of Pregnancy Between 13-20 Weeks of Gestation in Ethiopia
The purpose of the study is to determine the safety and effectiveness of dilation and evacuation for surgical abortion as compared to medical abortion
- Trial name
- NCT04602052
- Testing
- Dilation and evacuation
- Where
- Ethiopia
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- St. Paul's Hospital Millennium Medical College, Ethiopia
Abortion in First Trimester
Manual Versus Electric Vacuum Aspiration for Pregnancy Termination Between 10-14 Weeks
The study titled, Manual Versus Electric Vacuum Aspiration for Pregnancy Termination Between 10-14 weeks: A Randomized Trial, is a randomized trial to compare procedure times for manual and electric vacuum aspiration for surgical…
- Trial name
- NCT03079622
- Testing
- Electric Vacuum Aspiration, Manual Vacuum Aspiration
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Washington University School of Medicine
Medical Abortion
Comparison of the Safety and Efficacy of Medical Abortion Provided by Physicians and Midlevel Providers in Nepal
The purpose of the study is to compare the safety, effectiveness, and acceptability of medical abortion provided by doctors and midlevel providers in a developing country where doctors are scarce, such as Nepal.
- Trial name
- NCT01186302
- Testing
- Type of provider
- Where
- Nepal
- Volunteers
- 1,104 people
- Sponsor
- World Health Organization
Painless Abortion, Artificial Intelligence (AI)
Reinforcement Learned Automated Anesthesia Systems During Painless Abortion
This study compares the automated anesthesia systems for painless abortion (AAS-PA) with traditional anesthesia in painless abortions.
- Conditions
- Painless Abortion, Artificial Intelligence (AI), Ciprofol
- Trial name
- AAS-PA (NCT07132151)
- Testing
- AI Controlled General Anesthesia, General Anesthesia
- Where
- 8 sites in China
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Second Trimester Abortion
TENS Unit To Decrease Pain After Laminaria Insertion
The purpose of the study is to learn more about the transcutaneous nerve stimulation (TENS) unit, an over-the-counter option for pain relief that is not a medication.
- Trial name
- NCT06529003
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS) unit
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Queen's Medical Center
Termination of Pregnancy (TOP)
Interest of Cervical Dilators in Second Trimester Termination of Pregnancy
The purpose of this study is to evaluate whether the use of cervical dilators for cervical ripening in case of second trimester medical termination of pregnancy (TOP) is effective to reduce duration of labor.
- Trial name
- DILATOP (NCT03194230)
- Testing
- With cervical dilatator
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy, Ectopic, Early Pregnancy Loss
Beta-HCG Levels in Uterine Cavity Lavage for Pregnancies of Unknown Location
The goal of this interventional study is to investigate the role of beta-hCG levels in uterine cavity lavage for differentiating between ectopic pregnancy and early pregnancy loss in female patients aged 18-45 years.
- Trial name
- BHCG-UCL-DEP (NCT07048587)
- Testing
- Beta-hCG levels in the uterine cavity lavage for differential diagnosis in pregnancy of unknown locations and ectopic pregnancy
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Hypofibrinogenemia, Congenital, Afibrinogenemia, Congenital
Pregnancy and Fibrinogen Disorders
The aim of this observational study is to evaluate the prevalence of uncomplicated pregnancies in women suffering from congenital fibrinogen disorders (i.e, hypofibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia) as well as…
- Conditions
- Hypofibrinogenemia, Congenital, Afibrinogenemia, Congenital, Dysfibrinogenemia, Congenital
- Trial name
- FIBRINOGEST (NCT03920332)
- Where
- 3 sites in France, Slovakia and 1 more
- Volunteers
- 149 people
- Sponsor
- University Hospital, Geneva
Pregnancy
Task Sharing to Improve Post Abortion Care at District Health Care Level- Trial in Uganda
Uganda is one of the countries with highest fertility rate in the world, 6.7 children per women. It is estimated that 56 percent of all pregnancies are unintended and the contraceptive prevalence rate in Uganda is 23 percent.
- Trial name
- NCT01844024
- Testing
- misoprostol by midwife
- Where
- Uganda
- Volunteers
- 1,010 people
- Sponsor
- Karolinska Institutet