Clinical trials: Pregnancy Tests
Preterm Labor (24 GA - 32 GA)
Identification of Spontaneous Delivery Markers
The investigators project aims to identify, in pregnant women, discriminating molecules to allow an early detection of women who will spontaneously deliver prematurely, suitable in routine clinical practice.
- Trial name
- TrophY2 (NCT02225717)
- Testing
- Cervicovaginal swab
- Where
- France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer, Breast Cancer
Measuring and Improving the Safety of Test Result Follow-Up
Improving communication is foundational to improving patient safety. Electronic health records (EHRs) can improve communication, but also introduce unique vulnerabilities.
- Conditions
- Lung Cancer, Breast Cancer, Colon Cancer, Bladder Cancer
- Trial name
- NCT04166240
- Testing
- SAFER TRACKS Intervention
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Focal Segmental Glomerulosclerosis (FSGS)
A Study Evaluating the Relative Bioavailability and Food Effect of a Tablet Formulation of VX-147
The purpose of the study is to evaluate the relative bioavailability (BA) and the effect of food on the pharmacokinetics (PK), and the safety and tolerability of VX-147 test tablet formulation.
- Trial name
- NCT05955872
- Testing
- VX-147
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Vertex Pharmaceuticals Incorporated
Stress Urinary Incontinence
Value of Urodynamics Prior to Stress Incontinence Surgery
To test the value of preoperatively performed urodynamics with regard to outcome of surgery for stress urinary incontinence (SUI) and to examine whether not performing urodynamics preoperatively is more cost effective than…
- Trial name
- VUSIS (NCT00509730)
- Testing
- Urodynamics
- Where
- Netherlands
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Weight Reduction
Avoiding Diabetes After Pregnancy Trial
The Avoiding Diabetes After Pregnancy Trial (ADAPT) study was designed to test the effectiveness of interventions that potentially increase the adoption of Diabetes Prevention Program (DPP) elements by women who had a pregnancy…
- Trial name
- ADAPT (NCT01923350)
- Testing
- Weight Reduction Intervention, Weight Reduction Control Arm, Tested for diabetes
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Social & Scientific Systems Inc.
Nephrolithiasis
Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers
Kidney stones continue to affect more and more people in the United States with the most recent estimate being 1 in 9 people will develop a stone in their life.
- Trial name
- NCT06974357
- Testing
- Genetic testing
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ryan L Steinberg
Treponema Pallidum, Treponema Pallidum Infection
This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.
This study will evaluate the clinical performance of two investigational diagnostic kits developed by ALPCO: the Syphilis-T CLIA Kit and the Syphilis-NT CLIA Kit.
- Conditions
- Treponema Pallidum, Treponema Pallidum Infection, Syphilis Infection, Serum
- Trial name
- NCT07089836
- Testing
- ALPCO Syphilis-T, ALPCO Syphilis-NT CLIA Kits
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
This phase II trial tests whether the combination of nivolumab and ipilimumab is better than nivolumab alone to shrink tumors in patients with deficient mismatch repair system (dMMR) endometrial carcinoma that has come back after…
- Conditions
- Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma, Endometrial Endometrioid Adenocarcinoma
- Trial name
- NCT05112601
- Testing
- Biospecimen Collection, Computed Tomography, Ipilimumab
- Where
- 138 sites in United States
- Volunteers
- 81 people
- Sponsor
- National Cancer Institute (NCI)
Cervical Cancer
Self Collected Sampling in Non-attendees Cervical Cancer Screening: DNA Test and Molecular Triage for HPV Positive Women
The aims of the present study are to assess the effects of a hrHPV self-sampling test as strategies to reach non-attending women in organized cervical screening in comparison with standard recall by letter in 8000 women; to…
- Trial name
- NCT03183700
- Testing
- Self sampling device, Cervical ThinPrep sampling
- Where
- Italy
- Volunteers
- 8,000 people
- Sponsor
- Cancer Prevention and Research Institute, Italy
Advanced Endometrial Carcinoma, Metastatic Endometrial Carcinoma
Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
This phase I trial tests the safety, side effects, and best dose of combination therapy with pelcitoclax (APG-1252) and cobimetinib in treating patients with ovarian and endometrial cancers that have come back after a period of…
- Conditions
- Advanced Endometrial Carcinoma, Metastatic Endometrial Carcinoma, Metastatic Fallopian Tube Carcinoma, Metastatic Platinum-Resistant Ovarian Carcinoma
- Trial name
- NCT05691504
- Testing
- Biopsy Procedure, Biospecimen Collection, Cobimetinib
- Where
- 6 sites in United States
- Volunteers
- 42 people
- Sponsor
- National Cancer Institute (NCI)
Schistosomiasis Hematobium, Diagnostic
Schistosomiasis Diagnosis Using a CAA Antigen Test
Schistosomiasis is one of most important human parasitic diseases worldwide. Pregnant women and their infants are two vulnerable population groups, particularly in sub-Saharan Africa, where - amongst other infectious agents …
- Conditions
- Schistosomiasis Hematobium, Diagnostic, Drug Reaction, Pregnancy
- Trial name
- FreebiLyGAB (NCT03779347)
- Testing
- Praziquantel, UCP-LF CAA, composite diagnostic
- Where
- 2 sites in Gabon
- Volunteers
- 100 people
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Infertility, Female
DuoStim in Cases of PGT: Comparison of Embryo Quantity and Embryonic Quality Using MitoScore
Since preimplantation genetic testing (PGT) is being more frequently requested from patients as women pursue infertility treatments at an advanced age with a poorer prognosis, sometimes physicians are compelled to perform several…
- Trial name
- NCT03291821
- Testing
- human menopausal gonadotropin, GnRH antagonist, GnRH analog
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- IVI Madrid
Kidney Failure, Chronic, Olfaction Disorders
Taste And Smell TEsting in End Stage Renal Disease
Malnutrition is an important complication of advanced kidney disease and impairment in smell and taste may affect nutritional status.
- Conditions
- Kidney Failure, Chronic, Olfaction Disorders, Taste Disorders, Malnutrition
- Trial name
- TASTE ESRD (NCT03043144)
- Testing
- Worsening of olfaction from enrollment visit to 6 months, Worsening of taste from enrollment visit to 6 months, Serum Zinc
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Ovarian Neoplasms
A Diagnostic Test to Evaluate Cancer Risk Before Surgery in Women With an Ovarian Mass
Ovarian cancer is a serious health risk with the highest death rate among gynecological cancers. Unfortunately, it's only possible to definitively diagnose ovarian cancer after surgery, as there are no reliable tests to determine…
- Trial name
- NCT06566716
- Testing
- CleoDX ovarian cancer test
- Where
- 19 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Cleo Diagnostics Ltd
Urinary Tract Infection Complicated, Urinary Tract Infection (cUTI)
Clinical Utility of a PCR Compared to Culture and Sensitivity Testing for the Management of cUTI in Adults.
Complicated urinary tract infections (cUTIs) often lead to the overuse of empiric antibiotics, risking inappropriate treatment and contributing to antimicrobial resistance.
- Conditions
- Urinary Tract Infection Complicated, Urinary Tract Infection (cUTI), Urinary Tract Infection (Diagnosis)
- Trial name
- PCR (NCT06996301)
- Testing
- Treatment guided by the PCR results, Treatment guided by the C&S results
- Where
- 6 sites in United States
- Volunteers
- 773 people
- Sponsor
- Doc Lab Inc
Hiv, Sexually Transmitted Infections (Not HIV or Hepatitis)
Improving Perinatal Outcomes Among Kenyan Pregnant Women With an Integrated STI Testing Model
The investigators will conduct a 3-arm individual-level RCT in Kisumu and Siaya, Kenya to compare perinatal outcomes associated with 3 models of STI testing and management in antenatal care.
- Trial name
- PrIMI (NCT06203951)
- Testing
- Xpert® CT/NG and TV testing
- Where
- 8 sites in Kenya
- Volunteers
- 3,132 people, healthy volunteers welcome
- Sponsor
- University of Washington
Platinum-sensitive Recurrent Serous Ovarian Cancer
OSCA - Olaparib Standard of CAre Study
This study will be carried out as a retrospective, non-interventional observational review of medical records for patients in multiple countries with platinum-sensitive recurrent serous ovarian cancer.
- Trial name
- OSCA (NCT02262273)
- Testing
- Data Collection
- Where
- 199 sites in Australia, Belgium and 11 more
- Volunteers
- 2,123 people
- Sponsor
- AstraZeneca
Pregnancy, Sexually Transmitted Diseases
The S.A.F.E. Study : Computer-Aided Counseling to Prevent Teen Pregnancy/Sexually Transmitted Diseases (STDs)
This is a randomized clinical trial assessing the efficacy of two types of counseling (Computer-Assisted Motivational Intervention [CAMI] versus Didactic Educational Counseling [DEC]) to see which can better reduce female…
- Trial name
- NCT00151151
- Testing
- Computer-Assisted Motivational Intervention, Didactic Educational Counseling
- Where
- United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Lung Cancer, Prostate Cancer
Cognitive Testing of Tobacco Use Measurement Items for Administration With Cancer Patients and Survivors
Background: People who have cancer have more medical problems if they smoke. Some studies show that smoking even makes cancer treatment less effective.
- Conditions
- Lung Cancer, Prostate Cancer, Bladder Cancer, Thymic Cancer
- Trial name
- NCT02233842
- Testing
- Participant interview
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Urinary Tract Infections
ADAPT-AST (Adaptive Antimicrobial Susceptibility Testing)
The goal of this study is to improve the way urinary tract infections (UTIs) are tested for antibiotic resistance. The main questions it aims to answer are: Can the investigators use a method called Bayesian causal inference to…
- Trial name
- ADAPT-AST (NCT06297837)
- Where
- United Kingdom
- Volunteers
- 500,000 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
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