Clinical trials: Pregnancy Trimester, Second
Pregnancy
5D Versus Conventional 2D Fetal Echocardiography During Second Trimester of Pregnancy
Hypothesis: In Women in the second trimester of pregnancy 5D offers an alternative method for fetal Echocardiography compared to conventional 2D scanning Question: Does 5D software technology is as efficient as 2D scanning in…
- Trial name
- NCT02675595
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Pregnant Women
Clinical Study on the Effect of Elevit Pregnancy 2nd & 3rd Trimester (Multi-micronutrients & DHA Supplement) on the Nutritional Status of Pregnant Women During Second and Third Trimester
The aim of this study is to collect information how adding a soft gel preparation of micronutrients such as vitamins, dietary minerals plus omega-3 fatty acid (docosahexaenoic acid, DHA) to the diet of pregnant women during the…
- Trial name
- NCT04438928
- Testing
- Elevit Pregnancy 2nd & 3rd Trimester, Non-Supplement
- Where
- 2 sites in Italy
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Bayer
Cervical Preparation
Dilapan Versus Laminaria
This is a randomized, blinded clinical trial comparing overnight laminaria versus same-day Dilapan for cervical preparation for surgical abortions occurring between fourteen and eighteen weeks gestation.
- Trial name
- DvL (NCT00775983)
- Testing
- laminaria, Dilapan-S
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Abortion, Induced
Mifepristone Plus Misoprostol Versus Misoprostol Alone for 2nd Trimester Abortion (14 - 21 Weeks Last Menstrual Period (LMP))
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00969982
- Testing
- mifepristone+misoprostol
- Where
- 2 sites in Moldova, Tunisia
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Late Second Trimester Termination of Pregnancy
Vaginal Misoprostol and Foley Catheter for Late Second Trimester Termination of Pregnancy
Vaginal Misoprostol Versus Combined Low Dose Misoprostol Plus Foley Catheter for Late Second Trimester Termination of Pregnancy With Previous Multiple Cesarean Sections
- Trial name
- NCT02989324
- Testing
- MisoprostoL, Foley Catheter
- Where
- Egypt
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Abortion, Blood Loss
Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion
Misoprostol is a medication used extensively in obstetrics and gynecology for its ability to aid in softening the cervix as well as decreasing blood loss after abortion or vaginal delivery.
- Trial name
- PreopMiso (NCT01436266)
- Testing
- Misoprostol, Folic acid
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston University
Vaginal Bleeding During Pregnancy
Tranexamic Acid in Pregnancies With Vaginal Bleeding
Tranexamic acid has been proposed and used for prevention and management of antepartum and postpartum hemorrhage.
- Trial name
- NCT03632824
- Testing
- Tranexamic Acid
- Where
- Iraq
- Volunteers
- 139 people
- Sponsor
- Hawler Medical University
Gingivitis, Pregnancy
Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)
This study will track changes in oral health in pregnant women. Subjects will be assigned to either regular oral care or advanced oral care and be given oral care products to use until they deliver.
- Trial name
- OHMOM (NCT01549587)
- Testing
- 0.243% sodium fluoride, toothbrush, dental floss
- Where
- 2 sites in United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Pregnancy Related
Comparison of Rocuronium Induced Neuromuscular Blockade in Late Second Trimester Pregnant and Non-pregnant Women
The present study is to compare the onset and duration of rocuronium in late second trimester women and non-pregnant women undergoing general anesthesia.
- Trial name
- NCT04253093
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Miscarriage
Could Colour Dopper Improve the Diagnosis of Retained Placental Fragments After Second Trimester Miscarriage ?
Value of pelvi- abdominal ultrasound and Doppler in diagnosis of retained products of conception after second trimester miscarriage to select who will benefit from surgical evacuations or conservative management.
- Trial name
- NCT02419300
- Testing
- ultrasoungraphy
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Ain Shams University
Abortion Second Trimester
Overnight Pain Treatment Investigating Opioids vs. Nonopioids
The purpose of this study is to compare maximum pain scores between patients seeking induced abortion and requiring cervical preparation with osmotic dilators.
- Trial name
- OPTION (NCT03545893)
- Testing
- Ibuprofen 600 mg, OxyCODONE 5 Mg Oral Tablet
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Pennsylvania
Termination of Pregnancy
Comparison of Surgical Versus Medical Termination of Pregnancy Between 13-20 Weeks of Gestation in Ethiopia
The purpose of the study is to determine the safety and effectiveness of dilation and evacuation for surgical abortion as compared to medical abortion
- Trial name
- NCT04602052
- Testing
- Dilation and evacuation
- Where
- Ethiopia
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- St. Paul's Hospital Millennium Medical College, Ethiopia
Lactation Suppressed, Second Trimester Abortion
Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
The goal of this clinical trial is to compare breast symptoms (lactation, engorgement, etc) of individuals who undergo a procedure for second trimester of pregnancy loss between 16 weeks and 20 weeks gestational age.
- Trial name
- NCT06123026
- Testing
- Cabergoline
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Gestational Diabetes
The Value of Second-trimester Uterine Artery Doppler Analysis in the Prediction of GDM in a Low- Risk Population
In the current literature, there are not enough studies related to the use of uterine artery Doppler indices in the second trimester for the prediction of GDM.
- Trial name
- PS-GDM-2022 (NCT05488197)
- Testing
- uterine artery doppler at 18-23 weeks of pregnancy
- Where
- Turkey (Türkiye)
- Volunteers
- 700 people
- Sponsor
- Haseki Training and Research Hospital
Abortion Induced Complicated, Abortion
Second Trimester Abortion With Letrozole and Misoprostol Compared to Misoprostol Alone
Termination of Second trimester Abortion with Letrozole and Misoprostol Compared to Misoprostol Alone
- Trial name
- NCT07767435
- Testing
- · Misoprostol + letrozole, misoprostol alone
- Volunteers
- 80 people
- Sponsor
- Sohag University
Retained Placenta
Management of Third-stage of Labor After Second Trimester Medical Pregnancy Termination
Prospective randomized trail which compare 2 regimens for third-stage management after second trimester medical pregnancy termination : 10UI intra venous oxytocin or no additional medication after fetal expulsion.
- Trial name
- ANDDROID (NCT02969447)
- Testing
- Administration of 10 units of intra venous oxytocin after fetal expulsion
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Bordeaux
Contraception Behavior
Immediate vs. Delayed Insertion of Copper T 380A IUD After Termination of Pregnancy Over 12-weeks Gestation
The purpose of this study is to compare delayed vs. immediate insertion of the Copper T 380 IUD after termination of pregnancy after 12 weeks.
- Trial name
- NCT00540046
- Testing
- Copper T 380A IUD
- Where
- 2 sites in United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Dilation and Evacuation
Cervical Ripening Balloons for Same-Day Cervical Prep
The goal of this clinical trial is to learn if a cervical ripening balloon (Foley balloon) works to prepare the cervix before same-day outpatient dilation and evacuation (D\&E).
- Trial name
- CRB (NCT06964373)
- Testing
- Cervical Ripening Balloon, Osmotic Dilators
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of New Mexico
Arrhythmia, ECG Changes
Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy
In second trimester abortion above 22 weeks the investigators usually inject intra-cardiac Kcl for feticide. Digoxin intra-amniotic injection has been described in the literature in doses of 1-1.5 mg.
- Conditions
- Arrhythmia, ECG Changes, Hypotension
- Trial name
- NCT01951079
- Testing
- Intra-amniotic injection of DIGOXIN
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Preeclampsia (PE)
Validation of the MaiRa Preeclampsia Test for Screening Early/Late Preeclampsia in First and Second Trimesters
Preeclampsia (PE) is a major obstetric complication with severe short- and long-term consequences for both mother and fetus. Early detection is critical to mitigate PE-related morbidity and mortality.
- Trial name
- iPregnostic (NCT06716242)
- Testing
- Peripheral blood collection
- Where
- 11 sites in Spain
- Volunteers
- 7,473 people
- Sponsor
- iPremom